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Mies van Steenbergen

Technical Support Assistant for Teaching and Research - O profile 
Science
Pharmaceutical sciences
Pharmaceutics
Pharmaceutics
David de Wiedgebouw
Universiteitsweg 99
Kamer 3.19
3584 CG Utrecht

Mies van Steenbergen

Technical Support Assistant for Teaching and Research - O profile
Pharmaceutics
+31 6 13 091 855
m.j.vansteenbergen@uu.nl
Profile CV Publications Contact
Profile CV Publications Contact
Areas of expertise
Skills
Research areas

Publications

2024

Scholarly publications

Mesquita, B., Singh, A., Masdeu, C. P., Lokhorst, N., Hebels, E. R., van Steenbergen, M., Mastrobattista, E., Heger, M., van Nostrum, C. F., & Oliveira, S. (2024). Nanobody-mediated targeting of zinc phthalocyanine with polymer micelles as nanocarriers. International Journal of Pharmaceutics, 655, 1-12. Article 124004. https://doi.org/10.1016/j.ijpharm.2024.124004
https://dspace.library.uu.nl/bitstream/handle/1874/437680/1-s2.0-S0378517324002382-main.pdf?sequence=1
Viola, M., Ainsworth, M. J., Mihajlovic, M., Cedillo-Servin, G., van Steenbergen, M. J., van Rijen, M., de Ruijter, M., Castilho, M., Malda, J., & Vermonden, T. (2024). Covalent Grafting of Functionalized MEW Fibers to Silk Fibroin Hydrogels to Obtain Reinforced Tissue Engineered Constructs. Biomacromolecules, 25(3), 1563-1577. https://doi.org/10.1021/acs.biomac.3c01147
https://dspace.library.uu.nl/bitstream/handle/1874/436896/viola-et-al-2024-covalent-grafting-of-functionalized-mew-fibers-to-silk-fibroin-hydrogels-to-obtain-reinforced-tissue.pdf?sequence=1

2023

Scholarly publications

Hebels, E. R., van Steenbergen, M. J., Haegebaert, R., Seinen, C. W., Mesquita, B. S., van den Dikkenberg, A., Remaut, K., Rijcken, C. J. F., van Ravensteijn, B. G. P., Hennink, W. E., & Vermonden, T. (2023). Mechanistic Study on the Degradation of Hydrolysable Core-Crosslinked Polymeric Micelles. Langmuir, 39(34), 12132-12143. https://doi.org/10.1021/acs.langmuir.3c01399

2022

Scholarly publications

Evers, M. J. W., Du, W., Yang, Q., Kooijmans, S. A. A., Vink, A., van Steenbergen, M., Vader, P., de Jager, S. C. A., Fuchs, S. A., Mastrobattista, E., Sluijter, J. P. G., Lei, Z., & Schiffelers, R. (2022). Delivery of modified mRNA to damaged myocardium by systemic administration of lipid nanoparticles. Journal of Controlled Release, 343, 207-216. https://doi.org/10.1016/j.jconrel.2022.01.027
Wang, Y., Thies-Weesie, D. M. E., Bosman, E. D. C., van Steenbergen, M. J., van den Dikkenberg, J., Shi, Y., Lammers, T., van Nostrum, C. F., & Hennink, W. E. (2022). Tuning the size of all-HPMA polymeric micelles fabricated by solvent extraction. Journal of controlled release : official journal of the Controlled Release Society, 343, 338-346. https://doi.org/10.1016/j.jconrel.2022.01.042

2021

Scholarly publications

Su, X., Ramírez-Escudero, M., Sun, F., van den Dikkenberg, J. B., van Steenbergen, M. J., Pieters, R. J., Janssen, B. J. C., van Hasselt, P. M., Hennink, W. E., & van Nostrum, C. F. (2021). Internalization and transport of PEGylated lipid-based mixed micelles across Caco-2 cells mediated by scavenger receptor B1. Pharmaceutics, 13(12), 1-22. Article 2022. https://doi.org/10.3390/pharmaceutics13122022
Ojha, T., Hu, Q., Colombo, C., Wit, J., van Geijn, M., van Steenbergen, M. J., Bagheri, M., Königs-Werner, H., Buhl, E. M., Bansal, R., Shi, Y., Hennink, W. E., Storm, G., Rijcken, C. J. F., & Lammers, T. (2021). Lyophilization stabilizes clinical-stage core-crosslinked polymeric micelles to overcome cold chain supply challenges. Biotechnology Journal, 16(6), Article 2000212. https://doi.org/10.1002/biot.202000212
Scheiner, K. C., Maas-Bakker, R. F., van Steenbergen, M. J., Schwendeman, S. P., Hennink, W. E., & Kok, R. J. (2021). Post-loading of proangiogenic growth factors in PLGA microspheres. European Journal of Pharmaceutics and Biopharmaceutics, 158, 1-10. https://doi.org/10.1016/j.ejpb.2020.10.022

2020

Scholarly publications

Wang, Y., van Steenbergen, M. J., Beztsinna, N., Shi, Y., Lammers, T., van Nostrum, C. F., & Hennink, W. E. (2020). Biotin-decorated all-HPMA polymeric micelles for paclitaxel delivery. Journal of controlled release : official journal of the Controlled Release Society, 328, 970-984. https://doi.org/10.1016/j.jconrel.2020.09.013
Liu, Y., Van Steenbergen, M. J., Zhong, Z., Oliveira, S., Hennink, W. E., & Van Nostrum, C. F. (2020). Dithiolane-Crosslinked Poly(ϵ-caprolactone)-Based Micelles: Impact of Monomer Sequence, Nature of Monomer, and Reducing Agent on the Dynamic Crosslinking Properties. Macromolecules, 53(16), 7009–7024. https://doi.org/10.1021/acs.macromol.0c01031
Shi, H., van Steenbergen, M. J., Lou, B., Liu, Y., Hennink, W. E., & Kok, R. J. (2020). Folate decorated polymeric micelles for targeted delivery of the kinase inhibitor dactolisib to cancer cells. International Journal of Pharmaceutics, 582, Article 119305. https://doi.org/10.1016/j.ijpharm.2020.119305
Najafi, M., Asadi, H., Van Den Dikkenberg, J., Van Steenbergen, M. J., Fens, M. H. A. M., Hennink, W. E., & Vermonden, T. (2020). Conversion of an Injectable MMP-Degradable Hydrogel into Core-Cross-Linked Micelles. Biomacromolecules, 21(5), 1739-1751. https://doi.org/10.1021/acs.biomac.9b01675
Jong, J. A. W., Guo, Y., Veenhoven, C., Moret, M.-E., van der Zwan, J., Lucini Paioni, A., Baldus, M., Scheiner, K. C., Dalebout, R., van Steenbergen, M. J., Verhaar, M. C., Smakman, R., Hennink, W. E., Gerritsen, K. G. F., & van Nostrum, C. F. (2020). Phenylglyoxaldehyde-Functionalized Polymeric Sorbents for Urea Removal from Aqueous Solutions. ACS Applied Polymer Materials, 2(2), 515-527. https://doi.org/10.1021/acsapm.9b00948

2019

Scholarly publications

Ojha, T., Pathak, V., Drude, N., Weiler, M., Rommel, D., Rütten, S., Geinitz, B., van Steenbergen, M. J., Storm, G., Kiessling, F., & Lammers, T. (2019). Shelf-Life Evaluation and Lyophilization of PBCA-Based Polymeric Microbubbles. Pharmaceutics, 11(9), Article 433. https://doi.org/10.3390/pharmaceutics11090433
Shi, H., Lou, B., van Steenbergen, M. J., Sijbrandi, N. J., Hennink, W. E., & Kok, R. J. (2019). Polymeric Micelles Employing Platinum(II) Linker for the Delivery of the Kinase Inhibitor Dactolisib. Particle and Particle Systems Characterization, 36(8), Article 1900236. https://doi.org/10.1002/ppsc.201900236
https://dspace.library.uu.nl/bitstream/handle/1874/390418/Shi_et_al_2019_Particle_Particle_Systems_Characterization.pdf?sequence=1
Shi, H., Leonhard, W. N., Sijbrandi, N. J., van Steenbergen, M. J., Fens, M. H. A. M., van de Dikkenberg, J. B., Toraño, J. S., Peters, D. J. M., Hennink, W. E., & Kok, R. J. (2019). Folate-dactolisib conjugates for targeting tubular cells in polycystic kidneys. Journal of controlled release : official journal of the Controlled Release Society, 293, 113-125. https://doi.org/10.1016/j.jconrel.2018.11.019

2018

Scholarly publications

Domínguez Pardo, J. J., Koorengevel, M. C., Uwugiaren, N., Weijers, J., Kopf, A. H., Jahn, H., van Walree, C. A., van Steenbergen, M. J., & Killian, J. A. (2018). Membrane Solubilization by Styrene-Maleic Acid Copolymers: Delineating the Role of Polymer Length. Biophysical Journal, 115(1), 129-138. https://doi.org/10.1016/j.bpj.2018.05.032
https://dspace.library.uu.nl/bitstream/handle/1874/374068/1_s2.0_S0006349518306714_main.pdf?sequence=1
Sun, F., Adrian, M., Beztsinna, N., van den Dikkenberg, J. B., Maas-Bakker, R. F., van Hasselt, P. M., van Steenbergen, M. J., Su, X., Kapitein, L. C., Hennink, W. E., & van Nostrum, C. F. (2018). Influence of PEGylation of vitamin-K-loaded mixed micelles on the uptake by and transport through Caco-2 cells. Molecular Pharmaceutics, 15(9), 3786–3795. https://doi.org/10.1021/acs.molpharmaceut.8b00258

2017

Scholarly publications

Chen, W., Clauser, J., Thiebes, A. L., McGrath, D. J., Kelly, N., van Steenbergen, M. J., Jockenhoevel, S., Steinseifer, U., McHugh, P. E., Hennink, W. E., & Kok, R. J. (2017). Gefitinib/gefitinib microspheres loaded polyurethane constructs as drug-eluting stent coating. European Journal of Pharmaceutical Sciences, 103, 94-103. https://doi.org/10.1016/j.ejps.2017.02.002
Louage, B., Van Steenbergen, M. J., Nuhn, L., Risseeuw, M. D. P., Karalic, I., Winne, J., Van Calenbergh, S., Hennink, W. E., & De Geest, B. G. (2017). Micellar paclitaxel-initiated raft polymer conjugates with acid-sensitive behavior. ACS Macro Letters, 6(3), 272-276. https://doi.org/10.1021/acsmacrolett.6b00977
https://dspace.library.uu.nl/bitstream/handle/1874/359092/acsmacrolett.6b00977.pdf?sequence=1
Kasmi, S., Louage, B., Nuhn, L., Verstraete, G., Van Herck, S., Van Steenbergen, M. J., Vervaet, C., Hennink, W. E., & De Geest, B. G. (2017). Acrylamides with hydrolytically labile carbonate ester side chains as versatile building blocks for well-defined block copolymer micelles via RAFT polymerization. Polymer Chemistry, 8(42), 6544-6557. https://doi.org/10.1039/c7py01345k
Dominguez Pardo, J. J., Dörr, J. M., Renne, M. F., Ould-Braham , T., Koorengevel, M. C., van Steenbergen, M., & Killian, J. A. (2017). Thermotropic properties of phosphatidylcholine nanodiscs bounded by styrene-maleic acid copolymers. Chemistry and Physics of Lipids, 208, 58-64. https://doi.org/10.1016/j.chemphyslip.2017.08.010

2016

Scholarly publications

Liu, J., Hennink, W. E., Van Steenbergen, M. J., Zhuo, R., & Jiang, X. (2016). A facile modular approach toward multifunctional supramolecular polyplexes for targeting gene delivery. Journal of Materials Chemistry B, 4(43), 7022-7030. https://doi.org/10.1039/c6tb01671e
https://dspace.library.uu.nl/bitstream/handle/1874/344547/facile.pdf?sequence=1
Liu, J., Hennink, W. E., Van Steenbergen, M. J., Zhuo, R., & Jiang, X. (2016). Versatile Supramolecular Gene Vector Based on Host-Guest Interaction. Bioconjugate Chemistry, 27(4), 1143-1152. https://doi.org/10.1021/acs.bioconjchem.6b00094
https://dspace.library.uu.nl/bitstream/handle/1874/346103/Versatile.pdf?sequence=1
Chen, Y., van Steenbergen, M. J., Li, D., van den Dikkenberg, J., Lammers, T., van Nostrum, C. F., Metselaar, J. M., & Hennink, W. E. (2016). Polymeric Nanogels with Tailorable Degradation Behavior. Macromolecular Bioscience, 16(8), 1122-1137. https://doi.org/10.1002/mabi.201600031
https://dspace.library.uu.nl/bitstream/handle/1874/344546/Polymeric.pdf?sequence=1
Chen, Y., van Steenbergen, M. J., Li, D., van den Dikkenberg, J., Lammers, T., van Nostrum, C. F., Metselaar, J. M., & Hennink, W. E. (2016). Macromol. Biosci. 8/2016. Macromolecular Bioscience, 16(8), 1097. https://doi.org/10.1002/mabi.201670029
https://dspace.library.uu.nl/bitstream/handle/1874/344545/Chen_et_al_2016_Macromolecular_Bioscience.pdf?sequence=1
Naksuriya, O., van Steenbergen, M. J., Sastre Torano, J., Okonogi, S., & Hennink, W. E. (2016). A Kinetic Degradation Study of Curcumin in Its Free Form and Loaded in Polymeric Micelles. The AAPS journal, 18(3), 777-787. https://doi.org/10.1208/s12248-015-9863-0
https://dspace.library.uu.nl/bitstream/handle/1874/341355/A_Kinetic_Degradation_Study_of_Curcumin_in_Its_Free_Form_and_Loaded.pdf?sequence=1

2015

Scholarly publications

Rood, J., Nawzad, H., Kalicharan, R., Van Steenbergen, M., & Vromans, H. (2015). Drug release from an oromucosal paste for the selective decontamination of the oropharynx (in ICU patients and healthy volunteers). European Journal of Pharmaceutical Sciences, 73, 88-92. https://doi.org/10.1016/j.ejps.2015.03.025
https://dspace.library.uu.nl/bitstream/handle/1874/314756/1_s2.0_S0928098715001414_main.pdf?sequence=1
Martens, T. F., Remaut, K., Deschout, H., Engbersen, J. F. J., Hennink, W. E., Van Steenbergen, M. J., Demeester, J., De Smedt, S. C., & Braeckmans, K. (2015). Coating nanocarriers with hyaluronic acid facilitates intravitreal drug delivery for retinal gene therapy. Journal of Controlled Release, 202, 83-92. https://doi.org/10.1016/j.jconrel.2015.01.030

2014

Scholarly publications

Fransen, M. F., Cordfunke, R. A., Sluijter, M., Van Steenbergen, M. J., Drijfhout, J. W., Ossendorp, F., Hennink, W. E., & Melief, C. J. M. (2014). Effectiveness of slow-release systems in CD40 agonistic antibody immunotherapy of cancer. Vaccine, 32(15), 1654-1660. https://doi.org/10.1016/j.vaccine.2014.01.056
Samadi, N., van Steenbergen, M. J., van den Dikkenberg, J. B., Vermonden, T., van Nostrum, C. F., Amidi, M., & Hennink, W. E. (2014). Nanoparticles Based on a Hydrophilic Polyester with a Sheddable PEG Coating for Protein Delivery. Pharmaceutical Research, 31(10), 2593-2604. https://doi.org/10.1007/s11095-014-1355-x
Boere, K. W. M., Visser, J., Seyednejad, H., Rahimian, S., Gawlitta, D., Van Steenbergen, M. J., Dhert, W. J. A., Hennink, W. E., Vermonden, T., & Malda, J. (2014). Covalent attachment of a three-dimensionally printed thermoplast to a gelatin hydrogel for mechanically enhanced cartilage constructs. Acta Biomaterialia, 10(6), 2602-2611. https://doi.org/10.1016/j.actbio.2014.02.041

2013

Scholarly publications

Samadi, N., Abbadessa, A., Di Stefano, A., Van Nostrum, C. F., Vermonden, T., Rahimian, S., Teunissen, E. A., Van Steenbergen, M. J., Amidi, M., & Hennink, W. E. (2013). The effect of lauryl capping group on protein release and degradation of poly(d,l-lactic-co-glycolic acid) particles. Journal of Controlled Release, 172(2), 436-443. https://doi.org/10.1016/j.jconrel.2013.05.034
Shi, Y., van Steenbergen, M. J., Teunissen, E. A., Novo, L., Gradmann, S., Baldus, M., van Nostrum, C. F., & Hennink, W. E. (2013). Π−Π Stacking increases the stability and loading capacity of thermosensitive polymeric micelles for chemotherapeutic drugs. Biomacromolecules, 14(6), 1826-1837. https://doi.org/10.1021/bm400234c

2012

Scholarly publications

Ghassemi, A. H., Van Steenbergen, M. J., Barendregt, A., Talsma, H., Kok, R. J., Van Nostrum, C. F., Crommelin, D. J. A., & Hennink, W. E. (2012). Controlled release of octreotide and assessment of peptide acylation from poly(D,L-lactide-co-hydroxymethyl glycolide) compared to PLGA microspheres. Pharmaceutical Research, 29(1), 110-120. https://doi.org/10.1007/s11095-011-0517-3

2011

Scholarly publications

D'Aurizio, E., van Nostrum, C. F., van Steenbergen, M. J., Sozio, P., Siepmann, F., Siepmann, J., Hennink, W. E., & Di Stefano, A. (2011). Preparation and characterization of poly(lactic-co-glycolic acid) microspheres loaded with a labile antiparkinson prodrug. International Journal of Pharmaceutics, 409(1-2), 289-96.
Varkouhi, A. K., Lammers, T., Schiffelers, R. M., van Steenbergen, M. J., Hennink, W. E., & Storm, G. (2011). Gene silencing activity of siRNA polyplexes based on biodegradable polymers. European Journal of Pharmaceutics and Biopharmaceutics, 77(3), 450-7.
Spee, D. A., Bakker, R., van der Werf, C. H. M., van Steenbergen, M. J., Rath, J. K., & Schropp, R. E. I. (2011). Polymer layers by initiated chemical vapor deposition for thin film gas barrier encapsulation. Thin Solid Films, 519(14), 4479-4482. https://doi.org/10.1016/j.tsf.2011.01.297
Bakker, R., Weijers, P., Spee, D. A., van Steenbergen, M. J., van der Werf, C. H. M., Rath, J. K., & Schropp, R. E. I. (2011). Synthesis of poly(meta-diethynyl benzene) with initiated chemical vapour deposition. Thin Solid Films, 519(14), 4418-4420. https://doi.org/10.1016/j.tsf.2011.01.310

2010

Scholarly publications

Varkouhi, A. K., Schiffelers, R. M., van Steenbergen, M. J., Lammers, T., Hennink, W. E., & Storm, G. (2010). Photochemical internalization (PCI)-mediated enhancement of gene silencing efficiency of polymethacrylates and N,N,N-trimethylated chitosan (TMC) based siRNA polyplexes. Journal of controlled release : official journal of the Controlled Release Society, 148(1).
Ghassemi, A. H., van Steenbergen, M. J., Talsma, H., van Nostrum, C. F., Jiskoot, W., Crommelin, D. J., & Hennink, W. E. (2010). Microspheres of hydrophilic PLGA highly attractive for protein delivery. Journal of controlled release : official journal of the Controlled Release Society, 148(1).
Ghassemi, A. H., Van Steenbergen, M. J., Talsma, H., Van Nostrum, C. F., Jiskoot, W., Crommelin, D. J. A., & Hennink, W. E. (2010). Microspheres of hydrophilic PLGA highly atractive for protein delivery. Journal of Controlled Release, 148(1), 39-40. https://doi.org/10.1016/j.jconrel.2010.07.047
Ghassemi, A. H., van Steenbergen, M. J., Talsma, H., van Nostrum, C. F., Crommelin, D. J. A., & Hennink, W. E. (2010). Hydrophilic polyester microspheres: effect of molecular weight and copolymer composition on release of BSA. Pharmaceutical Research, 27(9), 2008-17.

2009

Scholarly publications

Ghassemi, A. H., van Steenbergen, M. J., Talsma, H., van Nostrum, C. F., Jiskoot, W., Crommelin, D. J. A., & Hennink, W. E. (2009). Preparation and characterization of protein loaded microspheres based on a hydroxylated aliphatic polyester, poly(lactic-co-hydroxymethyl glycolic acid). Journal of Controlled Release, 138(1), 57-63. https://doi.org/10.1016/j.jconrel.2009.04.025
Vente, M. A. D., Nijsen, J. F. W., de Roos, R., van Steenbergen, M. J., Kaaijk, C. N. J., Koster-Ammerlaan, M. J. J., de Leege, P. F. A., Hennink, W. E., van het Schip, A. D., & Krijger, G. C. (2009). Neutron activation of holmium poly(L-lactic acid) microspheres for hepatic arterial radioembolization: a validation study. Biomed Microdevices, 11(4), 763-772. http://www.ncbi.nlm.nih.gov/pubmed/19241172
Verheul, R. J., Amidi, M., van Steenbergen, M. J., van Riet, E., Jiskoot, W., & Hennink, W. E. (2009). Influence of the degree of acetylation on the enzymatic degradation and in vitro biological properties of trimethylated chitosans. Biomaterials, 30(18), 3129-3135.
Censi, R., Vermonden, T., van Steenbergen, M. J., Deschout, H., Braeckmans, K., de Smedt, S. C., van Nostrum, C. F., di Martino, P., & Hennink, W. E. (2009). Photopolymerized thermosensitive hydrogels for tailorable diffusion-controlled protein delivery. Journal of Controlled Release, 140(3), 230-6.
Eggenhuisen, T. M., van Steenbergen, M. J., Talsma, H., de Jongh, P. E., & de Jong, K. P. (2009). Impregnation of mesoporous silica for catalyst preparation studied with differential scanning calorimetry. Journal of Physical Chemistry C, 113(38), 16785-16791.
Seyednejad, S. H., Vermonden, T., Fedorovich, N. E., van Eijk, R., van Steenbergen, M. J., Dhert, W. J. A., van Nostrum, C. F., & Hennink, W. E. (2009). Synthesis and characterization of hydroxyl-functionalized caprolactone copolymers and their effect on adhesion, proliferation, and differentiation of human mesenchymal stem cells. Biomacromolecules, 10(11), 3048-3054. https://doi.org/10.1021/bm900693p

2008

Scholarly publications

Lin, C., Blaauboer, C. J., Timoneda, M. M., Lok, M. C., van Steenbergen, M. J., Hennink, W. E., Zhong, Z., Feijen, J., & Engbersen, J. F. J. (2008). Bioreducible poly(amido amine)s with oligoamine side chains: Synthesis, characterization, and structural effects on gene delivery. Journal of Controlled Release, 126, 166-174.
Luten, J., van Steenbergen, M. J., Lok, M. C., de Graaff, A. M., van Nostrum, C. F., Talsma, H., & Hennink, W. E. (2008). Degradable PEG-folate coated poly(DMAEA-co-BA)phosphazene-based polyplexes exhibit receptor-specific gene expression. European Journal of Pharmaceutical Sciences, 33(3), 241-251.

2007

Scholarly publications

Loontjens, C. A. M., Vermonden, T., Leemhuis, M., Van Steenbergen, M. J., Van Nostrum, C. F., & Hennink, W. E. (2007). Synthesis and characterization of random and triblock copolymers of ε-caprolactone and (benzylated)hydroxymethyl glycolide. Macromolecules, 40(20), 7208-7216. https://doi.org/10.1021/ma071165w
Carstens, M. G., Bevernage, J. J. L., van Nostrum, C. F., van Steenbergen, M. J., Flesch, F. M., Verrijk, R., de Leede, L., Crommelin, D. J. A., & Hennink, W. E. (2007). Small oligomeric micelles based on end group modified mPeg-oligocaprolactone with monodisperse hydrophobic blocks. Macromolecules, 40, 116-122.
Vugt-Wensink, K. D. F., Meijer, Y. J., van Steenbergen, M. J., Verrijk, R., Jiskoot, W., Crommelin, D. J. A., & Hennink, W. E. (2007). Effect of excipients on the encapsulation efficiency and release of human growth hormone from dextran microspheres. European Journal of Pharmaceutics and Biopharmaceutics, 67, 589-596.
Hiemstra, C., Zhong, Z., van Tomme, S. R., van Steenbergen, M. J., Jacobs, J. J., den Otter, W., Hennink, W. E., & Feijen, J. (2007). In vitro and in vivo protein delivery from in situ forming poly(ethylene glycol)-poly lactide hydrogels. Journal of Controlled Release, 119, 320-327.
de Wolf, H. K., de Raad, M., Snel, C. J., van Steenbergen, M. J., Fens, M. H. A. M., Storm, G., & Hennink, W. E. (2007). Biodegradable poly(2-dimethylamino ethylamino)phosphazene for in vivo gene delivery to tumor cells. Effect of polymer molecular weight. Pharmaceutical Research, 24, 1572-1580.
Hiemstra, C., Zhong, Z., van Steenbergen, M. J., Hennink, W. E., & Feijen, J. (2007). Release of model proteins and basic fibroblast growth factor from in situ forming degradable dextran hydrogels. Journal of Controlled Release, 122, 71-78.
Loontjens, C. A. M., Vermonden, T., Leemhuis, M., van Steenbergen, M. J., van Nostrum, C. F., & Hennink, W. E. (2007). Synthesis and characterization of random and triblock copolymers of -caprolactone and (benzylated)hydroxymethyl glycolide. Macromolecules, 40, 7208-7216.
de Jong, W. H., Dormans, J. A. M. A., van Steenbergen, M. J., Verharen, H. W., & Hennink, W. E. (2007). Tissue response in the rat and the mouse to degradable dextran hydrogels. Journal of Biomedical Materials Research, 83, 538-545.

2006

Scholarly publications

Jiang, X., van der Horst, A., van Steenbergen, M. J., Akeroyd, N., van Nostrum, C. F., Schoenmakers, P. J., & Hennink, W. E. (2006). Aqueous size-exclusion chromatography of cationic polymers for gene delivery. Journal of controlled release : official journal of the Controlled Release Society, 116(2). https://doi.org/10.1016/j.jconrel.2006.09.055
Vermonden, T., Besseling, N. A. N., van Steenbergen, M. J., & Hennink, W. E. (2006). Rheological studies of thermosensitive triblock copolymer hydrogels. Langmuir, 22, 10180-10184.
Metz, B., Kersten, G. F. A., Baart, G. J. E., de Jong, A., Meiring, H. D., ten Hove, J., van Steenbergen, M. J., Hennink, W. E., Crommelin, D. J. A., & Jiskoot, W. (2006). Identification of formaldehyde-induced modifications in proteins: reactions with insulin. Bioconjugate Chemistry, 17, 815-822.
Jiang, X., van der Horst, A., van Steenbergen, M. J., Akeroyd, N., van Nostrum, C. F., Schoenmakers, P. J., & Hennink, W. E. (2006). Molar-mass characterization of cationic polymers for gene delivery by aqueous size-exclusion chromatography. Pharmaceutical Research, 23, 595-603.

2005

Scholarly publications

den Brok, M. W. J., Nuijen, B., Kettenes-van den Bosch, J. J., van Steenbergen, M. J., Buluran, J. N., Harvey, M. D., Grieshaber, C. K., & Beijnen, J. H. (2005). Pharmaceutical development of a parenteral lyophilised dosage form for the novel anticancer agent C1311. PDA Journal of Pharmaceutical Science and Technology, 59(5), 285-297.
van Tomme, S. R., van Steenbergen, M. J., de Smedt, S. C., van Nostrum, C. F., & Hennink, W. E. (2005). Self-gelling hydrogels based on oppositely charged dextran microspheres. Biomaterials, 26(14), 2129-2135.
https://dspace.library.uu.nl/bitstream/handle/1874/11899/tomme_05_selfgellinghydrogels.pdf?sequence=2

2004

Scholarly publications

Vermonden, T., Van Steenbergen, M. J., Besseling, N. A. M., Marcelis, A. T. M., Hennink, W. E., Sudhölter, E. J. R., & Cohen Stuart, M. A. (2004). Linear rheology of water-soluble reversible neodymium(III) coordination polymers. Journal of the American Chemical Society, 126(48), 15802-15808.
Arigita, C., van den Berg, J., Wensink, K. D. F., van Steenbergen, M. J., Hennink, W. E., Crommelin, D. J. A., Kersten, G. F. A., & Jiskoot, W. (2004). Immunogenicity of meningococcal PorA formulations encapsulated in biodegradable microspheres. European Journal of Pharmaceutical Sciences, 21, 131-141.
Janssen, A. H., Talsma, H., van Steenbergen, M. J., & de Jong, K. P. (2004). Homogeneous nucleation of water in mesoporous zeolite cavities. Langmuir, 20, 41-45.
https://dspace.library.uu.nl/bitstream/handle/1874/14450/Langmuir-Janssen-2004.pdf?sequence=1

Other output

Hennink, W. E., van Nostrum, C. F., van Steenbergen, M. J., Soga, S. O., & Rijcken, C. J. F. (2004). Temperature sensitive polymers. (Patent No. 10/804,302).

2003

Scholarly publications

Neradovic, D., van Steenbergen, M. J., Vansteelant, L., Meijer, Y. J., van Nostrum, C. F., & Hennink, W. E. (2003). Degradation mechanism and kinetics of thermosensitive polyacrylamides containing lactic acid side chains. Macromolecules, 36, 7491-7498.
Bouma, M., Nuijen, B., Harms, R., Rice, J. R., Nowotnik, D. P., Stewart, D. R., Jansen, B. A. J., van Zutphen, S., Reedijk, J., van Steenbergen, M. J., Talsma, H., Bult, A., & Beijnen, J. H. (2003). Pharmaceutical development of a parenteral lyophilized formulation of the investigational polymer-conjugated platinum anticancer agent AP5280. Drug Development and Industrial Pharmacy, 29, 981-995.

2002

Scholarly publications

Nijsen, J. F. W., Van Het Schip, A. D., Van Steenbergen, M. J., Zielhuis, S. W., Kroon-Batenburg, L. M. J., Van De Weert, M., Van Rijk, P. P., & Hennink, W. E. (2002). Influence of neutron irradiation on holmium acetylacetonate loaded poly(L-lactic acid) microspheres. Biomaterials, 23(8), 1831-1839. https://doi.org/10.1016/S0142-9612(01)00309-X
van de Weert, M., van Steenbergen, M. J., Cleland, J. L., Heller, J., Hennink, W. E., & Crommelin, D. J. A. (2002). Semisolid, self-catalyzed poly(ortho ester)s as controlled-release systems: protein release and protein stability issues. Journal of Pharmaceutical Sciences, 91, 1065-1074.
Meyvis, T. K. L., Stubbe, B., van Steenbergen, M. J., Hennink, W. E., de Smedt, S. C., & Demeester, J. (2002). A comparison between the use of dynamic mechanical analysis and oscillatory shear rheometry for the characterisation of hydrogels. International Journal of Pharmaceutics, 244, 163-168.
Bouma, M., Nuijen, B., Sava, G., Perbellini, A., Flaibani, A., van Steenbergen, M. J., Talsma, H., Kettenes-van den Bosch, J. J., Bult, A., & Beijnen, J. H. (2002). Pharmaceutical development of a parenteral lyophilized formulation of the antimetastatic ruthenium complex NAMI-A. International Journal of Pharmaceutics, 248, 247-259.

2001

Scholarly publications

Nijsen, J. F. W., Van Steenbergen, M. J., Kooijman, H., Talsma, H., Kroon-Batenburg, L. M. J., Van De Weert, M., Van Rijk, P. P., De Witte, A., Van Het Schip, A. D., & Hennink, W. E. (2001). Characterization of poly(L-lactic acid) microspheres loaded with holmium acetylacetonate. Biomaterials, 22(22), 3073-3081. https://doi.org/10.1016/S0142-9612(01)00055-2
Cadee, J. A., van Steenbergen, M. J., Versluis, C., Heck, A. J. R., Underberg, W. J. M., den Otter, W., Jiskoot, W., & Hennink, W. E. (2001). Oxidation of Recombinant Human interleukin-2 by Potassium Peroxodisulfate. Pharmaceutical Research, 18, 1461-1467.
Nijsen, J. F. W., van Steenbergen, M. J., Kooijman, H., Talsma, H., Kroon-Batenburg, L. M. J., van de Weert, M., van Rijk, P. P., de Witte, A., van het Schip, A. D., & Hennink, W. E. (2001). Characterization of poly (L-lactic acid) microspheres loaded with holmium aceylacetonate. Biomaterials, 22, 3073-3081.
Steendam, R., van Steenbergen, M. J., Hennink, W. E., Frijlink, H. W., & Lerk, C. F. (2001). Effect of molecular weight and glass transition on relaxation and release behaviour of poly(dl-lactic acid) tablets. Journal of Controlled Release, 70, 71-82.

2000

Scholarly publications

van de Wetering, P., Schuurmans-Nieuwenbroek, N. M. E., van Steenbergen, M. J., Crommelin, D. J. A., & Hennink, W. E. (2000). Copolymers of 2-(dimethylamino)ethyl methacrylate with ethoxytriethylene glycol methacrylate or N-vinyl-pyrrolidone as gene transfer agents. Journal of Controlled Release, 64, 193-203.

1999

Scholarly publications

van de Wetering, P., Moret, E. E., Schuurmans-Nieuwenbroek, N. M. E., van Steenbergen, M. J., & Hennink, W. E. (1999). Structure-activity relationships of water-soluble cationic methacrylate/methacrylamide polymers for nonviral gene delivery. Bioconjugate Chemistry, 10, 687-692.

1998

Scholarly publications

van de Wetering, P., Zuidam, N. J., van Steenbergen, M. J., van der Houwen, O. A. G. J., Underberg, W. J. M., & Hennink, W. E. (1998). A mechanistic study of the hydroltic stability of Poly(2-(dimethyl)aminoethyl methacrylate). Macromolecules, 31, 8063-8068.
van de Wetering, P., Zuidam, N. J., van Steenbergen, M. J., van der Houwen, O. A. G. J., Underberg, W. J. M., & Hennink, W. E. (1998). A mechanistic study of the hydrolytic stability of poly (2-(dimethylamino) ethyl methacrylate). Macromolecules, 31, 8063-8068.

1997

Scholarly publications

van der Voort Maarschalk, K., Zuurman, K., van Steenbergen, M. J., Hennink, W. E., Vromans, H., Bolhuis, G. K., & Lerk, C. F. (1997). Effect of compaction temperature on consolidation of amorphous copolymers with different glass transition temperatures. Pharmaceutical Research, 14, 415-419.
van Dijk-Wolthuis, W. N. E., van de Water, L., van de Wetering, P., van Steenbergen, M. J., Kettenes-van den Bosch, J. J., Schuyl, P. J. W., & Hennink, W. E. (1997). Synthesis and characterization of poly-L-lysine with controlled low molecular weight. Macromolecular Chemistry and Physics, 198, 3893-3907.
van Dijk-Wolthuis, W. N. E., van Steenbergen, M. J., Underberg, W. J. M., & Hennink, W. E. (1997). Degradation kinetics of methacrylated dextrans in aqueous solution. Journal of Pharmaceutical Sciences, 86, 413-417.
van Dijk-Wolthuis, W. N. E., Tsang, S. K. Y., van Steenbergen, M. J., Hoogeboom, C., & Hennink, W. E. (1997). Degradation and release behavior of dextran-based hydrogels. Macromolecules, 30, 4639-4645.

1995

Scholarly publications

van Dijk-Wotthuis, W. N. E., Franssen, O., Talsma, H., van Steenbergen, M. J., Kettenes-van den Bosch, J. J., & Hennink, W. E. (1995). Synthesis, Characterization, and Polymerization of Glycidyl Methacrylate Derivatized Dextran. Macromolecules, 28(18), 6317-6322. https://doi.org/10.1021/ma00122a044
Hennink, W. E., Franssen, O., Overbeek, A. Y., Van Steenbergen, M. J., & Talsma, H. (1995). Enzymatic degradation of dextran hydrogels. Proceedings of the Controlled Release Society, (22), 23-24.
De Smedt, S. C., Lauwers, A., Demeester, J., Van Steenbergen, M. J., Hennink, W. E., & Roefs, S. P. F. M. (1995). Characterization of the Network Structure of Dextran Glycidyl Methacrylate Hydrogels by Studying the Rheological and Swelling Behavior. Macromolecules, 28(14), 5082-5088. https://doi.org/10.1021/ma00118a042
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