Publications
2026
Scholarly publications
Hameete, B. C., Hogenkamp, A., & Groenink, L. (2026). Contributing to a (cell) cultural shift: Human platelet lysate is a suitable replacement for fetal calf serum when culturing the HTR8/SVneo extravillous trophoblast cell line. Toxicology in Vitro, 113, Article 106204. Advance online publication. [DOI] [Portal]
2025
Scholarly publications
Hameete, B. C., Hogenkamp, A., Ploesch, T., & Groenink, L. (2025). Corrigendum to “Poly(I:C) stimulates cytokine production, but not cell migration, in an extravillous trophoblast cell line” [J. Reprod. Immunol. 171 (2025) 104632]. Journal of Reproductive Immunology, 172, 1-1. Article 104799. [DOI] [Portal]
Kniffert, S., Buljan, I., Azevedo, F., Babinčák, P., Batinović, L., Evans, T. R., Garofalo, S., Graham, C., Groenink, L., Ihle, M., Klugar, M., Kočišová, L., Kohút, M., Kostomitsopoulos, N., Lacey, S., Lunić, A., Marušić, A., Nordström, T., Pennington, C. R., ... de Boer, M. R. (2025). Research methodology education in Europe: a multi-country, cross-disciplinary survey of current practices and perspectives. Research integrity and peer review, 10(1), Article 24. [DOI] [Portal]
Salwén, H., Holm, C., Achermann, G., Asaduzzaman, M., Blom, F., Dwojak-Matras, A., Groenink, L., Gruber, B., van den Hoven, M., Ristic, D. I., Iphofen, R., & Priess-Buchheit, J. (2025). Teaching research integrity: a manual of good practices: an outline. International Journal for Educational Integrity, 21(1), Article 13. [DOI] [Portal]
2024
Scholarly publications
2023
Scholarly publications
Kwee, C. M. B., Leen, N. A., Van der Kamp, R. C., Van Lissa, C. J., Cath, D. C., Groenink, L., & Baas, J. M. P. (2023). Anxiolytic effects of endocannabinoid enhancing compounds: A systematic review and meta-analysis. European Neuropsychopharmacology, 72, 79-94. [DOI] [Repository]
Heesbeen, E. J., Bijlsma, E. Y., Verdouw, P. M., van Lissa, C., Hooijmans, C., & Groenink, L. (2023). The effect of SSRIs on fear learning: a systematic review and meta-analysis. Psychopharmacology, 240(11), 2335-2359. [DOI] [Repository]
Groenink, L., Verdouw, P. M., Zhao, Y., Ter Heegde, F., Wever, K. E., & Bijlsma, E. Y. (2023). Pharmacological modulation of conditioned fear in the fear-potentiated startle test: a systematic review and meta-analysis of animal studies. Psychopharmacology, 240(11), 2361-2401. [DOI] [Repository]
Professional publications
Ebbelaar, C., Heersche, A., Buitelaar, N., Spierings, C., Groenink, L., Stroink, T., Sallevelt, B. T. G. M., Lafeber, M., & Pereira, R. R. (2023). Ebbelaar's Klinische psychofarmacologie deel 2: Psychofarmaca bij ADHD. PharmC.
2022
Scholarly publications
Kwee, C., Groenink, L., Leen, N. A., van Gerven, J. M. A., Cath, D. C., & Baas, J. (2022). Cannabidiol in anxiety research: a translational integration of preclinical and clinical studies. Neuroscience Applied, 1(S2), Article 100743. [DOI] [Repository]
Heesbeen, E., Verdouw, M., van Lissa, C., Hooijmans, C., Bijlsma, L., & Groenink, L. (2022). The effect of selective serotonin reuptake inhibitors on fear learning: a systematic review and meta-analysis. Neuroscience Applied, 1(S2), Article 100144. [DOI] [Repository]
Kwee, C. MB., van Gerven, J. MA., Bongaerts, F. LP., Cath, D. C., Jacobs, G., Baas, J. MP., & Groenink, L. (2022). Cannabidiol in clinical and preclinical anxiety research. A systematic review into concentration-effect relations using the IB-de-risk tool. Journal of Psychopharmacology, 36(12), 1299-1314. [DOI] [Repository]
Hart, E., Odé, Z., Derieppe, M. P. P., Groenink, L., Heymans, M. W., Otten, R., Lequin, M. H., Janssens, G. O. R., Hoving, E. W., & van Vuurden, D. G. (2022). Blood-brain barrier permeability following conventional photon radiotherapy - A systematic review and meta-analysis of clinical and preclinical studies. Clinical and Translational Radiation Oncology, 35, 44-55. [DOI] [Repository]
Kwee, C. M., Baas, J. M., van der Flier, F. E., Groenink, L., Duits, P., Eikelenboom, M., van der Veen, D. C., Moerbeek, M., Batelaan, N. M., van Balkom, A. J., & Cath, D. C. (2022). Cannabidiol enhancement of exposure therapy in treatment refractory patients with social anxiety disorder and panic disorder with agoraphobia: A randomised controlled trial. European Neuropsychopharmacology, 59, 58-67. [DOI] [Repository]
Professional publications
Ebbelaar, C., Heersche, A., Sallevelt, B. T. G. M., De Wit, L. E., Groenink, L., & Lafeber, M. (2022). Ebbelaar’s Klinische Psychofarmacologie: Deel 1 Antidepressiva. PharmC.
2021
Scholarly publications
Mantas, I., Millan, M. J., Di Cara, B., Groenink, L., Veiga, S., Cistarelli, L., Brocco, M., Bertrand, M., Svenningsson, P., & Zhang, X. (2021). Trace amine-associated receptor 1 contributes to diverse functional actions of o-phenyl-iodotyramine in mice but not to the effects of monoamine-based antidepressants. International Journal of Molecular Sciences, 22(16), 1-19. Article 8907. [DOI] [Repository]
Hameete, B. C., Fernández Calleja, J. M. S., de Groot, M. W. G. D. M., Oppewal, T. R., Tiemessen, M. M., Hogenkamp, A., de Vries, R. B. M., & Groenink, L. (2021). The poly(I:C)-induced maternal immune activation model; a systematic review and meta-analysis of cytokine levels in the offspring. Brain, Behavior, and Immunity, 11, Article 100192. [DOI] [Repository]
2020
Scholarly publications
Jansen, K., Pou Casellas, C., Groenink, L., Wever, K. E., & Masereeuw, R. (2020). Humans are animals, but are animals human enough? A systematic review and meta-analysis on interspecies differences in renal drug clearance. Drug Discovery Today, 25(4), 706-717. [DOI] [Repository]
2019
Scholarly publications
van der Flier, F. E., Kwee, C. M. B., Cath, D. C., Batelaan, N. M., Groenink, L., Duits, P., van der Veen, D. C., van Balkom, A. J. L. M., & Baas, J. M. P. (2019). Cannabidiol enhancement of exposure therapy in treatment refractory patients with phobias: study protocol of a randomized controlled trial. BMC Psychiatry, 19(69). [DOI] [Repository]
Zhao, Y., Bijlsma, E. Y., Ter Heegde, F., Verdouw, M. P., Garssen, J., Newman-Tancredi, A., & Groenink, L. (2019). Activation of somatodendritic 5-HT1A autoreceptors reduces the acquisition and expression of cued fear in the rat fear-potentiated startle test. Psychopharmacology, 236(4), 1171–1185. [DOI] [Repository]
2018
Scholarly publications
Milienne-Petiot, M., Higa, K. K., Grim, A., Deben, D., Groenink, L., Twamley, E. W., Geyer, M. A., & Young, J. W. (2018). Nicotine improves probabilistic reward learning in wildtype but not alpha7 nAChR null mutants, yet alpha7 nAChR agonists do not improve probabilistic learning. European Neuropsychopharmacology, 28(11), 1217-1231. [DOI] [Repository]
Zhao, Y., Bijlsma, E. Y., Verdouw, M. P., & Groenink, L. (2018). No effect of sex and estrous cycle on the fear potentiated startle response in rats. Behavioural Brain Research, 351, 24-33. [DOI] [Repository]
Zhao, Y., Bijlsma, E. Y., Verdouw, P. M., Garssen, J., & Groenink, L. (2018). The contribution of contextual fear in the anxiolytic effect of chlordiazepoxide in the fear-potentiated startle test. Behavioural Brain Research, 353, 57-61. [DOI] [Repository]
Man, J. H. K., Groenink, L., & Caiazzo, M. (2018). Cell reprogramming approaches in gene- and cell-based therapies for Parkinson's disease. Journal of Controlled Release, 286, 114-124. [DOI] [Repository]
2017
Scholarly publications
Milienne-Petiot, M., Groenink, L., Minassian, A., & Young, J. W. (2017). Blockade of dopamine D1-family receptors attenuates the mania-like hyperactive, risk-preferring, and high motivation behavioral profile of mice with low dopamine transporter levels. Journal of Psychopharmacology, 31(10), 1334-1346. [DOI] [Repository]
Verdouw, P. M., van Esterik, J. C. J., Peeters, B. W. M. M., Millan, M. J., & Groenink, L. (2017). CRF1 but not glucocorticoid receptor antagonists reduce separation-induced distress vocalizations in guinea pig pups and CRF overexpressing mouse pups. A combination study with paroxetine. Pharmacology Biochemistry and Behavior, 154, 11-19. [DOI] [Repository]
Professional publications
van den Hoven, M. A., Bolt, L. L. E., Ebbelaar, C. F., & Groenink, L. (2017). Ethiek voor apothekers. Boom.
2016
Scholarly publications
Szklany, K., De Theije, C. G. M., De Waard, C., Van Staveren, N. G., Van Wageningen, T. A., Wu, J., Verdouw, M., Van Limpt, K., Wopereis, H., Groenink, L., Oozeer, R., Garssen, J., Knippels, L. M. J., & Kraneveld, A. D. (2016). Effect of early life supplementation of non-digestible oligosaccharides on brain development and behaviour in healthy mice. European Neuropsychopharmacology, 26(S2), 191. [DOI]
Szklany, K., De Theije, C. G. M., De Waard, C., Van Staveren, N. G., Van Wageningen, T., Wu, J., Verdouw, M., Van Limpt, K., Wopereis, H., Groenink, L., Oozeer, R., Knippels, L. M. J., Garssen, J., & Kraneveld, A. D. (2016). Early life supplementation of 3% scGOS: lcGOS (9:1) leads to immuno-and neuromodulatory effects in healthy mice. Allergy: European Journal of Allergy and Clinical Immunology, 71, 291. [DOI]
Heitland, I., Groenink, L., van Gool, J. M., Domschke, K., Reif, A., & Baas, J. M. P. (2016). Human fear acquisition deficits in relation to genetic variants of the corticotropin releasing hormone receptor 1 and the serotonin transporter - revisited. Genes, Brain, and Behavior, 15(2), 209-220. [DOI] [Repository]
2015
Scholarly publications
Groenink, L., Verdouw, P. M., Bakker, B., & Wever, K. E. (2015). Pharmacological and methodological aspects of the separation-induced vocalization test in guinea pig pups; a systematic review and meta-analysis. European Journal of Pharmacology, 753, 191-208. [DOI] [Repository]
Hendriksen, H., & Groenink, L. (2015). Back to the future of psychopharmacology: A perspective on animal models in drug discovery. European Journal of Pharmacology, 759, 30-41. [DOI] [Repository]
Bijlsma, E. Y., Hendriksen, H., Baas, J. M. P., Millan, M. J., & Groenink, L. (2015). Lifelong disturbance of serotonin transporter functioning results in fear learning deficits: Reversal by blockade of CRF1 receptors. European Neuropsychopharmacology, 25(10), 1733-1743. [DOI] [Repository]
Groenink, L., Folkerts, G., & Schuurman, H.-J. (2015). European Journal of Pharmacology, Special issue on translational value of animal models: Introduction. European Journal of Pharmacology, 759, 1-2. [DOI] [Repository]
Kasahara, M., Groenink, L., Bijlsma, E. Y., Olivier, B., & Sarnyai, Z. (2015). Lifelong, central corticotropin-releasing factor (CRF) overexpression is associated with individual differences in cocaine-induced conditioned place preference. European Journal of Pharmacology, 753, 151-157. [DOI] [Repository]
2014
Scholarly publications
Douma, T. N., Millan, M. J., Boulay, D., Griebel, G., Verdouw, P. M., Westphal, K. G., Olivier, B., & Groenink, L. (2014). CRF1 receptor antagonists do not reverse pharmacological disruption of prepulse inhibition in rodents. Psychopharmacology, 231(7), 1289-1303. [DOI]
Douma, T. N., Millan, M. J., Verdouw, P. M., Oosting, R. S., Olivier, B., & Groenink, L. (2014). Valproate improves prepulse inhibition deficits induced by corticotropin-releasing factor independent of GABA(A) and GABA(B) receptor activation. Neuropharmacology, 79, 66-74. [DOI]
Other output
Baas, J. M. P., van Gool, J. M., Heitland, I., & Groenink, L. (2014). GENETIC DIFFERENCES IN THE CB1/CNR1 GENE MODULATE FEAR EXTINCTION IN HUMANS. Abstract from Annual International Cannabinoid Research Society Symposium on the Cannabinoids, Baveno, Italy.
2013
Scholarly publications
Van Gool, J. M., Baas, J. M. P., Heitland, I., Bijlsma, E. Y., & Groenink, L. (2013). A translational look at the serotonin transporter and corticotropin-releasing hormone in the acquisition of adaptive fear responses. European Neuropsychopharmacology, 23, 529-530. [DOI]
Heitland, I., Groenink, L., Bijlsma, E. Y., Oosting, R. S., & Baas, J. M. P. (2013). Corticotropin releasing hormone and serotonin-the neuropsychopharmacology of fear learning deficit from rodents to humans. European Neuropsychopharmacology, 23, 130. [DOI]
Heitland, I., Groenink, L., Bijlsma, E. Y., Oosting, R. S., & Baas, J. M. P. (2013). Human fear acquisition deficits in relation to genetic variants of the corticotropin releasing hormone receptor 1 and the serotonin transporter. PLoS One, 8(5), Article e63772. [DOI]
Other output
Heitland, I., Bijlsma, E. Y., Groenink, L., Evers, D., Oosting, R. S., Kenemans, J. L., & Baas, J. M. P. (2013). Human fear learning deficits depend on genetic variability in corticotropin releasing hormone receptor 1 in interaction with serotonergic polymorphisms. Poster session presented at Society for Neuroscience, San Diego, CA, USA.
Heitland, I., Groenink, L., Bijlsma, E. Y., Oosting, R. S., & Baas, J. M. P. (2013). Human fear learning deficits depend on genetic variability in corticotropin releasing hormone receptor 1 in interaction with serotonergic polymorphisms. Poster session presented at ECNP Workshop on Neuropsychopharmacology for Young Scientists in Europe, Nice, France.
2012
Scholarly publications
Vinkers, C. H., Hendriksen, H., van Oorschot, R., Cook, J. M., Rallipalli, S., Huang, S., Millan, M. J., Olivier, B., & Groenink, L. (2012). Lifelong CRF overproduction is associated with altered gene expression and sensitivity of discrete GABA(A) and mGlu receptor subtypes. Psychopharmacology, 219(3), 897-908. [DOI]
Vinkers, C. H., van Oorschot, R., Nielsen, E. Ø., Cook, J. M., Hansen, H. H., Groenink, L., Olivier, B., & Mirza, N. R. (2012). GABA(A) receptor α subunits differentially contribute to diazepam tolerance after chronic treatment. PLoS One, 7(8), e43054. [DOI]
Other output
Bijlsma, E. Y., van Gool, J. M., Baas, J. M. P., Olivier, B., & Groenink, L. (2012). Lifelong, but not acute or chronic, inactivation of the serotonin transporter hampers fear learning in rat fear-potentiated startle.. Paper presented at Society for Neuroscience, San Diego, CA, USA.
2011
Scholarly publications
Vinkers, C. H., Hendriksen, H., Cook, J., Rallipalli, S., Millan, M., Olivier, B., & Groenink, L. (2011). Life long crf overproduction is associated with changes in functional sensitivity and gene expression of GABAA and mglur receptor. Behavioural Pharmacology, 22, 41. [DOI]
Vinkers, C. H., Hendriksen, H., Cook, J., Rallipalli, S., Millan, M., Olivier, B., & Groenink, L. (2011). Life-long CRF overproduction is associated with changes in functional sensitivity and gene expression of GABA-A and mGluR receptor subtypes. European Neuropsychopharmacology, 21(S3), 542-543. [DOI]
Douma, T. N., Millan, M. J., Verdouw, P. M., Olivier, B., & Groenink, L. (2011). Valproic acid improves prepulse inhibition deficits in mice over-expressing corticotropin-releasing factor independent of GABA-A and GABA-B receptor activation. Behavioural Pharmacology, 22, 37-38. [DOI]
Groenink, L., Bijlsma, E. Y., van Bogaert, M. J. V., Oosting, R. S., & Olivier, B. (2011). Serotonin1A receptor deletion does not interact with maternal separation-induced increases in startle reactivity and prepulse inhibition deficits. Psychopharmacology, 214(1), 353-365. [DOI]
Kasahara, M., Groenink, L., Kas, M. J. H., Bijlsma, E. Y., Olivier, B., & Sarnyai, Z. (2011). Influence of transgenic corticotropin-releasing factor (CRF) over-expression on social recognition memory in mice. Behavioural Brain Research, 218(2), 357-362. [DOI]
Bijlsma, E. Y., van Leeuwen, M. L. F., Westphal, K. G. C., Olivier, B., & Groenink, L. (2011). Local repeated corticotropin-releasing factor infusion exacerbates anxiety- and fear-related behavior: differential involvement of the basolateral amygdala and medial prefrontal cortex. Neuroscience, 173, 82-92. [DOI]
Kasahara, M., Groenink, L., Olivier, B., & Sarnyai, Z. (2011). Corticotropin-releasing factor (CRF) over-expression down-regulates hippocampal dopamine receptor protein expression and CREB activation in mice. Neuroendocrinology Letters, 32(2), 193-198.
Vinkers, C. H., Groenink, L., Pattij, T., Olivier, B., & Bouwknecht, J. A. (2011). 5-HT(1A) receptor sensitivity in 5-HT(1B) receptor KO mice is unaffected by chronic fluvoxamine treatment. European Journal of Pharmacology, 667(1-3), 250-257. [DOI]
Douma, T. N., Kolarz, A., Postma, Y., Olivier, B., & Groenink, L. (2011). The amphetamine-chlordiazepoxide mixture, a pharmacological screen for mood stabilizers, does not enhance amphetamine-induced disruption of prepulse inhibition. Behavioural Brain Research, 225(1), 377-81. [DOI]
Douma, T. N., Millan, M. J., Olivier, B., & Groenink, L. (2011). Linking Stress and Schizophrenia: A Focus on Prepulse Inhibition. In T. Uehara (Ed.), Psychiatric Disorders - Trends and Developments (pp. 107-130). InTech.
Di Cara, B., Maggio, R., Aloisi, G., Rivet, J. M., Gregorsson Lundius, E., Yoshitake, T., Svenningsson, P., Brocco, M., Gobert, A., de Groote, L., Cistarelli, L., Veiga, S., de Montrion, C., Rodriguez, M., Galizzi, J. P., Lockhart, B. P., Cogé, F., Boutin, J. A., Vayer, P., ... Millan, M. J. (2011). Genetic Deletion of Trace Amine 1 Receptors Reveals Their Role in Auto-Inhibiting the Actions of Ecstasy (MDMA). Journal of Neuroscience, 31, 16928-16940.
Vinkers, C. H., Hendriksen, H., van Oorschot, R., Cook, J. M., Rallipalli, S., Huang, S., Millan, M. J., Olivier, B., & Groenink, L. (2011). Lifelong CRF overproduction is associated with altered gene expression and sensitivity of discrete GABAA and mGlu receptor subtypes. Psychopharmacology.
2010
Scholarly publications
Vinkers, C. H., Oosting, R. S., van Bogaert, M. J. V., Olivier, B., & Groenink, L. (2010). Early-Life Blockade of 5-HT1A Receptors Alters Adult Anxiety Behavior and Benzodiazepine Sensitivity. Biological Psychiatry, 67(4), 309-316. [DOI]
Vinkers, C. H., Olivier, B., Bouwknecht, J. A., Groenink, L., & Olivier, J. D. A. (2010). Stress-induced hyperthermia, the serotonin system and anxiety. Open Pharmacology Journal, 4(1), 15-29.
Vinkers, C. H., van Oorschot, R., Korte, S. M., Olivier, B., & Groenink, L. (2010). 5-HT1A receptor blockade reverses GABA(A) receptor alpha(3) subunit-mediated anxiolytic effects on stress-induced hyperthermia. Psychopharmacology, 211(2), 123-130. [DOI]
Vinkers, C. H., Oosting, R. S., van Bogaert, M. J. V., Olivier, B., & Groenink, L. (2010). Early-life blockade of 5-HT(1A) receptors alters adult anxiety behavior and benzodiazepine sensitivity. Biological Psychiatry, 67(4), 309-16.
Vinkers, C. H., Bijlsma, E. Y., Houtepen, L. C., Westphal, K. G. C., Veening, J. G., Groenink, L., & Olivier, B. (2010). Medial amygdala lesions differentially influence stress responsivity and sensorimotor gating in rats. Physiology & behavior, 99(3), 395-401.
Bijlsma, E. Y., Oosting, R. S., Olivier, B., & Groenink, L. (2010). Disrupted startle modulation in animal models for affective disorders. Behavioural Brain Research, 208(2), 383-90.
Vinkers, C. H., van Oorschot, R., Korte, S. M., Olivier, B., & Groenink, L. (2010). 5-HT1A receptor blockade reverses GABA(A) receptor alpha3 subunit-mediated anxiolytic effects on stress-induced hyperthermia. Psychopharmacology, 211(2), 123-30.
Prins, J., Denys, D. A., Westphal, K. G., Korte-Bouws, G. A., Quinton, M. S., Schreiber, R., Groenink, L., Olivier, B., & Korte, S. M. (2010). The putative antidepressant DOV 216,303, a triple reuptake inhibitor, increases monoamine release in the prefrontal cortex of olfactory bulbectomized rats. European Journal of Pharmacology, 633(1-3), 55-61. [DOI]
Bijlsma, E. Y., de Jongh, R., Olivier, B., & Groenink, L. (2010). Fear-potentiated startle, but not light-enhanced startle, is enhanced by anxiogenic drugs. Pharmacology, Biochemistry and Behavior, 96(1), 24-31.
Bijlsma, E. Y., Olivier, B., & Groenink, L. (2010). Cocaine-induced changes in affective state modulate the light-enhanced startle response. Behavioural Brain Research, 213(1), 117-20.
2009
Scholarly publications
Vinkers, C. H., Van Oorschot, R., Olivier, B., & Groenink, L. (2009). Stress-induced hyperthermia in the mouse. In T. D. Gould (Ed.), Mood and Anxiety Related Phenotypes in Mice: Characterization Using Behavioral Tests (pp. 139–152). Humana Press. [DOI]
Vinkers, C. H., Van Oorschot, R., Olivier, B., & Groenink, L. (2009). Stress-induced hyperthermia in the mouse. In T. Gould (Ed.), Mood and Anxiety Related Phenotypes in Mice: Characterization Using Behavioral Tests (pp. 139-152). (Neuromethods; Vol. 42). [DOI]
Groenink, L., Vinkers, C., van Oorschot, R., & Olivier, B. (2009). Models of anxiety: Stress-induced hyperthermia (SIH) in singly housed. Current Protocols in Pharmacology, (SUPPL. 45), 5.16.1-5.16.12. [DOI]
Breuer, M. E., Van Gaalen, M. M., Wernet, W., Claessens, S. E. F., Oosting, R. S., Behl, B., Korte, S. M., Schoemaker, H., Gross, G., Olivier, B., & Groenink, L. (2009). SSR149415, a non-peptide vasopressin V1b receptor antagonist, has long-lasting antidepressant effects in the olfactory bulbectomy-induced hyperactivity depression model. Naunyn-Schmiedeberg's Archives of Pharmacology, 379(1), 101-106. [DOI]
Vinkers, C. H., Breuer, M. E., Westphal, K. G. C., Korte, S. M., Oosting, R. S., Olivier, B., & Groenink, L. (2009). Olfactory bulbectomy induces rapid and stable changes in basal and stress-induced locomotor activity, heart rate and body temperature responses in the home cage. Neuroscience, 159(1), 39-46. [DOI]
Vinkers, C. H., Groenink, L., van Bogaert, M. J. V., Westphal, K. G. C., Kalkman, C. J., van Oorschot, R., Oosting, R. S., Olivier, B., & Korte, S. M. (2009). Stress-induced hyperthermia and infection-induced fever: Two of a kind? Physiology & behavior, 98(1-2), 37-43. [DOI]
Breuer, M. E., Groenink, L., Oosting, R. S., Buerger, E., Korte, S. M., Ferger, B., & Olivier, B. (2009). Antidepressant effects of pramipexole, a dopamine D3/D2 receptor agonist, and 7-OH-DPAT, a dopamine D3 receptor agonist, in olfactory bulbectomized rats. European Journal of Pharmacology, 616, 134-140.
Vinkers, C. H., Klanker, M., Groenink, L., Korte, S. M., Cook, J. M., Van Linn, M. L., Hopkins, S. C., & Olivier, B. (2009). Dissociating anxiolytic and sedative effects of GABA(A)ergic drugs using temperature and locomotor responses to acute stress. Psychopharmacology, 204(2), 299-311. [DOI]
Vinkers, C. H., de Jong, N. M., Kalkman, C. J., Westphal, K. G. C., van Oorschot, R., Olivier, B., Korte, S. M., & Groenink, L. (2009). Stress-induced hyperthermia is reduced by rapid-acting anxiolytic drugs independent of injection stress in rats. Pharmacology, Biochemistry and Behavior, 93(4), 413-418. [DOI]
Veening, J. G., Bocker, K. B. E., Oppelaar-Verdouw, P. M., Olivier, B., de Jongh, R., & Groenink, L. (2009). Activation of the septohippocampal system differentiates anxiety from fear in startle paradigms. Neuroscience, 163(4), 1046-1060.
Breuer, M. E., van Gaalen, M. M., Wernet, W., Claessens, S. E. F., Oosting, R. S., Behl, B., Korte, S. M., Schoemaker, H., Gross, G., Olivier, B., & Groenink, L. (2009). SSR149415, a non-peptide vasopressin V(1b) receptor antagonist, has long-lasting antidepressant effects in the olfactory bulbectomy-induced hyperactivity depression model. Naunyn-Schmiedeberg's Archives of Pharmacology, 379, 101-106.
Other output
Vinkers, C. H., Klanker, M., Korte, S. M., Groenink, L., & Olivier, B. (2009). ANXIOLYTIC AND SEDATIVE FUNCTIONS OF GABAA RECEPTOR SUBUNITS IN THE ACUTE STRESS RESPONSE. Naunyn-Schmiedeberg's Archives of Pharmacology, 380(3), 260-260.
2008
Scholarly publications
Groenink, L., Bijlsma, E. Y., & Olivier, B. (2008). Fear-potentiated startle and light-enhanced startle models in drug discovery. Current Protocols in Pharmacology, (SUPPL. 41). [DOI]
Groenink, L., Verdouw, P. M., van Oorschot, R., & Olivier, B. (2008). Models of anxiety: Ultrasonic vocalizations of isolated rat pups. Current Protocols in Pharmacology, (SUPPL. 43), 5.18.1-5.18.14. [DOI]
Vinkers, C. H., van Bogaert, M. J. V., Klanker, M., Korte, S. M., Oosting, R., Hanania, T., Hopkins, S. C., Olivier, B., & Groenink, L. (2008). Translational aspects of pharmacological research into anxiety disorders: The stress-induced hyperthermia (SIH) paradigm. European Journal of Pharmacology, 585(2-3), 407-425. [DOI]
Groenink, L., Bijlsma, E. Y., & Olivier, B. (2008). Fear-potentiated startle and light-enhanced startle models in drug dicovery. Current Protocols in Pharmacology, 5.48.1-5.48.15.
Breuer, M. E., Chan, J. S. W., Oosting, R. S., Groenink, L., Korte, S. M., Campbell, U., Schreiber, R., Hanania, T., Snoeren, E. M. S., Waldinger, M., & Olivier, B. (2008). The triple monoaminergic reuptake inhibitor DOV 216,303 has antidepressant effects in the rat olfactory bulbectomy model and lacks sexual side effects. European Neuropsychopharmacology, 18(12), 908-916. [DOI]
Groenink, L., Dirks, A., Verdouw, P. M., de Graaff, M., Peeters, B. W., Millan, M. J., & Olivier, B. (2008). CRF1 not glucocorticoid receptors mediate prepulse inhibition deficits in mice overexpressing CRF. Biological Psychiatry, 63, 360-368.
2007
Scholarly publications
Breuer, M. E., Groenink, L., Oosting, R. S., Westenberg, H. G. M., & Olivier, B. (2007). Long-term behavioral changes after cessation of chronic antidepressant treatment in olfactory bulbectomized rats. Biological Psychiatry, 61(8), 990-995. [Repository]
Kasahara, M., Groenink, L., Breuer, M. E., Olivier, B., & Sarnyai, Z. (2007). Altered behavioural adaptation in mice with neural corticotrophin-releasing factor overexpression. Genes, Brain, and Behavior, 6, 598-607. [Repository]
2006
Scholarly publications
Dirks, A., Groenink, L., & Olivier, B. (2006). Mutant Mouse Models of Bipolar Disorder: Are There Any? In Contemporary Clinical Neuroscience (pp. 265-285). (Contemporary Clinical Neuroscience). Springer Nature. [DOI]
Van Bogaert, M., Oosting, R., Toth, M., Groenink, L., van Oorschot, R., & Olivier, B. (2006). Effects of genetic background and null mutation of 5-HT1A receptors on basal and stress-induced body temperature: Modulation by serotonergic and GABAA-ergic drugs. European Journal of Pharmacology, 550(1-3), 84-90. [DOI] [Portal]
Dirks, A., Groenink, L., & Olivier, B. (2006). Mutant models of bipolar disorder: Are there any? In G. S. Fish, & J. Flint (Eds.), Transgenic and knockout models of neuropsychiatric disorders (pp. 265-286). Humana Press.
van den Bergh, F. S., Spronk, M., Ferreira, L., Bloemarts, E. M. M., Groenink, L., Olivier, B., & Oosting, R. S. (2006). Relationship of delay aversion and response inhibition to extinction learning, aggression, and sexual behaviour. Behavioural Brain Research, 175, 75-81. [Repository]
van Bogaert, M. J. V., Groenink, L., Oosting, R. S., Westphal, K. G. C., van der Gugten, J., & Olivier, B. (2006). Mouse strain differences in autonomic responses to stress. Genes, Brain, and Behavior, 5, 139-149. [Repository]
van Bogaert, M. J. V., Oosting, R. S., Toth, M., Groenink, L., van Oorschot, R., & Olivier, B. (2006). Effects of genetic background and null mutation of 5-HT(1A) receptors on basal and stress-induced body temperature: Modulation by serotonergic and GABA(A)-ergic drugs. European Journal of Pharmacology, 550, 84-90. [Repository]
van den Bergh, F. S., Bloemarts, E. M. M., Chan, J. S. W., Groenink, L., Olivier, B., & Oosting, R. S. (2006). Spontaneously hypertensive rats do not predict symptoms of attention-deficit hyperactivity disorder. Pharmacology, Biochemistry and Behavior, 83, 380-390. [Repository]
Körösi, A., Veening, J. G., Kozicz, T., Henckens, M., Dederen, P. J. W. C., Groenink, L., van der Gugten, J., Olivier, B., & Roubos, E. W. (2006). Distribution and expression of CRF receptor 1 and 2 mRNAs in the CRF over-expressing mouse brain. Brain Research, 1072, 46-54. [Repository]
van den Bergh, F. S., Bloemarts, E. M. M., Groenink, L., Olivier, B., & Oosting, R. S. (2006). Delay aversion: Effects of 7-OH-DPAT, 5-HT1A/1B-receptor stimulation and d-cycloserine. Pharmacology, Biochemistry and Behavior, 85, 736-743.
Other output
van Bogaert, M. J. V., Groenink, L., Oosting, R. S., Toth, M., & Olivier, B. (2006). The 5-HT1A receptor knockout mouse and anxiety. 99. Abstract from 4th Dutch Endo-Neuro-Psycho Meeting, Doorwerth.
Kasahara, M., Breuer, M. E., Belfield, J., Chawla, S., Chan, J. S. W., van den Bergh, F. S., Groenink, L., Olivier, B., & Sarnyai, Z. (2006). Enhanced sensitivity to cocaine in mice overexpressing corticotrophin-releasing factor (CRF): possible role of neuroadaptations in intracellular signalling systems. Abstract from SfN Meeting, Atlanta, USA.
Groenink, L., Dirks, A., Peeters, A., Millan, M. J., & Olivier, B. (2006). Prepulse inhibition deficits in mice overexpressing corticotrophin releasing factor (CRF): relative contributions of CRF1 receptors and corticosterone. Abstract from SfN Meeting, Atlanta, USA.
Breuer, M. E., Groenink, L., Oosting, R. S., & Olivier, B. (2006). Long lasting effects of anti-depressants on olfactory bulbectomy induced hyperactivity in the open field. S39-S40. Abstract from 2006 ECNP Workshop on Neuropsychopharmacology, Nice, Frankrijk.
van Bogaert, M. J. V., Groenink, L., Oosting, R. S., & Olivier, B. (2006). Stress-induced hyperthermia paradigm: Hyperthermia or fever?. Abstract from SfN Meeting, Atlanta, USA.
Oosting, R. S., van Bogaert, M. J. V., de Meijer, D., Hendriksen, H., Olivier, B., & Groenink, L. (2006). Postnatal, pharmacological induction of a functional 5-HT1A receptor knock-out mouse. Abstract from SfN Meeting, Atlanta, USA.
2005
Scholarly publications
de Jongh, R., Geyer, M. A., Olivier, B., & Groenink, L. (2005). The effects of sex and neonatal maternal separation on fear-potentiated and light-enhanced startle. Behavioural Brain Research, 161(2), 190-6.
Professional publications
Olivier, B., van Bogaert, M. J. V., van Oorschot, R., Oosting, R. S., & Groenink, L. (2005). Stress-induced hyperthermia. In T. Steckler, N. H. Kalin, & J. M. H. M. Reul (Eds.), Handbook of Stress and the Brain (pp. 135-155). Elsevier.
Other output
Veening, J. G., de Jongh, R., Verdouw, P. M., van der Gugten, J., Olivier, B., & Groenink, L. (2005). Fear-potentiated-startle and light-enhanced-startle induce different patterns of Fos-immunoreactivity in the male rat brain. Abstract from SfN Neuroscience Meeting, Washington DC.
Groenink, L., & Olivier, B. (2005). Translation of animal models to human psychopathology. S93. Abstract from Abstracts of the 8th ECNP Regional Meeting, Moscow, Russia.
van Bogaert, M. J. V., Gerritsen, L., Groenink, L., Oosting, R. S., & Olivier, B. (2005). The 5-HT1A and GABA-A-benzodiazepine receptors: Effects in behavior and pharmacology in female 5HT1A knockout mice. S32. Abstract from ECNP Workshop on Neuropsychopharmacology for Young Scientists in Europe.
Kasahara, M., Chan, J. S. W., Breuer, M. E., van den Bergh, F. S., Belfield, J., Chawla, S., Groenink, L., Olivier, B., & Sarnyai, Z. (2005). Enhanced sensitization to cocaine in mice overexpressing corticotrophin-releasing factor (CRF). Abstract from SfN Neuroscience Meeting, Washington DC.
2004
Scholarly publications
Bouwknecht, J. A., van der Gugten, J., Groenink, L., Olivier, B., & Paylor, R. (2004). Effects of repeated testing in two inbred strains on flesinoxan dose-response curves in three mouse models for anxiety. European Journal of Pharmacology, 494, 35-44.
Veening, J. G., Bouwknecht, J. A., Joosten, H. J. J., Dederen, P. J. W. C., Zethof, T. J. J., Groenink, L., van der Gugten, J., & Olivier, B. (2004). Stress-induced hyperthermia in the mouse: c-fos expression, corticosterone and temperature changes. Progress in Neuro-Psychopharmacology & Biological Psychiatry, 28, 699-707.
Bouwknecht, J. A., van der Gugten, J., Groenink, L., Olivier, B., & Paylor, R. (2004). Behavioral and physiological mouse models for anxiety: effects of flesinoxan in 129S6/SvEvTac and C57BL/6J mice. European Journal of Pharmacology, 494, 45-53.
Kozicz, T., Körösi, A., Korsman, C., Tilburg-Ouwens, D. T. W. M., Groenink, L., Veening, J. G., van der Gugten, J., Roubos, E. W., & Olivier, B. (2004). Urocortin expression in the Edinger-Westphal nucleus is down-regulated in the transgenic mice overexpressing neuronal corticotropin releasing factor. Neuroscience, 123, 589-594.
Other output
Breuer, M. E., Groenink, L., Westenberg, H. G. M., & Olivier, B. (2004). Long-term effects of olfactory bulbectomy on open field hyperactivity in rats. Poster session presented at Society for Neuroscience, San Diego, U.S.A..
van den Bergh, F. S., Bloemarts, E. M. M., Groenink, L., Oosting, R. S., & Olivier, B. (2004). A behavioral and pharmacological assessment of the spontaneously hypertensive rat as a model for attention-deficit hyperactivity disorder. 214. Abstract from 8th Dutch Endo-Neuro-Psycho Meeting, Doorwerth, Netherlands.
van den Bergh, F. S., Bloemarts, E. M. M., Groenink, L., Oosting, R. S., & Olivier, B. (2004). A behavioral and pharmacological assessment of the spontaneously hypertensive rat as a model for attention-deficit hyperactivity disorder. Poster session presented at Society for Neuroscience, San Diego, U.S.A..
Breuer, M. E., Groenink, L., Westenberg, H. G. M., & Olivier, B. (2004). Long-term effects of olfactory bulbectomy on open field hyperactivity in rats. 37. Abstract from FIGON Dutch Medicines Days 2004.
van Bogaert, M. J. V., Groenink, L., Oosting, R. S., & Olivier, B. (2004). Mouse strain differences in sensitivity towards anxiolytic drugs, a telemetric study. Poster session presented at Endo-Neuro-Psycho Meeting, Doorwerth (Parkhotel).
Dirks, A., Groenink, L., & Olivier, B. (2004). Prepulse inhibition and human neuropsychiatric disorders. 119. Abstract from 8th Dutch Endo-Neuro-Psycho Meeting, Doorwerth, Netherlands.
van Bogaert, M. J. V., Groenink, L., Oosting, R. S., & Olivier, B. (2004). Mouse strain differences in sensitivity towards serotonergic drugs, a telemetric study. Poster session presented at Serotonin Club Meeting, Porto, Portugal.
van Bogaert, M. J. V., Groenink, L., Oosting, R. S., & Olivier, B. (2004). Mouse strain differences in autonomic response to both serotonergic and GABA - ergic drugs. Poster session presented at Society for Neuroscience, San Diego, U.S.A..
Dirks, A., Olivier, B., van der Gugten, J., Tuinstra, T., & Groenink, L. (2004). Effects of fluvoxamine on HPA-axis reactivity in transgenic mice overexpressing corticotropin-releasing factor. S22-S23. Abstract from ECNP Workshop on Neuropsychopharmacology for Young Scientist in Europe, Nice, France.
van Bogaert, M. J. V., Groenink, L., Oosting, R. S., & Olivier, B. (2004). Mouse strain differences in sensitivity towards anxiolytic drugs, a telemetric study. 168. Abstract from 8th Dutch Endo-Neuro-Psycho Meeting, Doorwerth, Netherlands.
van Bogaert, M. J. V., Groenink, L., Oosting, R. S., & Olivier, B. (2004). Mouse strain differences in autonomic response to both serotonergic and GABA-ergic drugs. Poster session presented at Neuroscience Meeting, San Diego, U.S.A..
Dirks, A., Olivier, B., van der Gugten, J., Tuinstra, T., & Groenink, L. (2004). Effects of fluvoxamine on HPA-axis reactivity in transgenic mice overexpressing corticotropin-releasing factor. Abstract from ISPNE XXXV Annual Meeting, Glasgow, Scotland.
van Bogaert, M. J. V., Groenink, L., Oosting, R. S., & Olivier, B. (2004). Mouse strain differences in sensitivity towards anxiolytic drugs, a telemetric study. 36. Abstract from FIGON Dutch Medicines Days 2004.
Breuer, M. E., Groenink, L., Westenberg, H. G. M., & Olivier, B. (2004). Long-term effects of olfactory bulbectomy on open field hyperactivity in rats. Poster session presented at 8th Dutch Endo-Neuro-Psycho Meeting, Doorwerth, Netherlands.
de Jongh, R., Groenink, L., van der Gugten, J., & Olivier, B. (2004). Fear versus anxiety: sex, drugs and neural pathways. 118. Abstract from 8th Dutch Endo-Neuro-Psycho Meeting, Doorwerth, Netherlands.
2003
Scholarly publications
De Jongh, R., Groenink, L., Van Der Gugten, J., & Olivier, B. (2003). Light-enhanced and fear-potentiated startle: Temporal characteristics and effects of α-helical corticotropin-releasing hormone. Biological Psychiatry, 54(10), 1041-1048. [DOI]
de Jongh, R., Groenink, L., van der Gugten, J., & Olivier, B. (2003). Light-enhanced and fear-potentiated startle: temporal characteristics and effects of alpha-helical corticotropin-releasing hormone. Biological Psychiatry, 54, 1041-1048.
Groenink, L., Pattij, T., de Jongh, R., van der Gugten, J., Oosting, R. S., Dirks, A., & Olivier, B. (2003). 5-HT1A receptor knockout mice and mice overexpressing corticotropin-releasing hormone in models of anxiety. European Journal of Pharmacology, 463, 185-197.
Groenink, L., van Bogaert, M. J. V., van der Gugten, J., Oosting, R. S., & Olivier, B. (2003). 5-HT1A receptor and 5-HT1B receptor knockout mice and stress and anxiety paradigms. Behavioural Pharmacology, 14, 369-383.
Olivier, B., Zethof, T. J. J., Pattij, T., van Bogaert, M. J. V., van Oorschot, R., Leahy, C., Oosting, R. S., Bouwknecht, J. A., Veening, J. G., van der Gugten, J., & Groenink, L. (2003). Stress-induced hyperthermia and anxiety: pharmacological validation. European Journal of Pharmacology, 463, 117-132.
Pattij, T., Broersen, L. M., van der Linde, J., Groenink, L., van der Gugten, J., Maes, R. A. A., & Olivier, B. (2003). Operant learning and differential-reinforcement-of-low-rate 36-s responding in 5-HT1A and 5-HT1B receptor knockout mice. Behavioural Brain Research, 141, 137-145.
Dirks, A., Groenink, L., Westphal, K. G. C., Olivier, J. D. A., Oppelaar-Verdouw, P. M., van der Gugten, J., Geyer, M. A., & Olivier, B. (2003). Reversal of startle gating deficits in transgenic mice overexpressing corticotropin-releasing factor by antipsychotic drugs. Neuropsychopharmacology, 28, 1790-1798.
Other output
Kozicz, T., Groenink, L., Körösi, A., Olivier, B., & Roubos, E. W. (2003). Urocortin expression in the Edinger-Westphal nucleus is down regulated in transgenic mice over-expressing neuronal corticotropin-releasing factor. 168. Abstract from 2nd Dutch Endo-Neuro-Psycho Meeting (7th Endo-Neuro-Meeting).
Diergaarde, L., Groenink, L., & van Ree, J. M. (2003). Effects of neonatal excitotoxic lesions of rat basolateral amygdala on behavioral flexibility. 219. Abstract from 2nd Dutch Endo-Neuro-Psycho Meeting (7th Endo-Neuro-Meeting).
Böcker, K. B. E., Baas, J. M. P., de Jongh, R., van den Bergh, F. S., Bron, L. J. C., Groenink, L., & Kenemans, J. L. (2003). Fear potentiation and dark enhancement of startle in humans. S30. Abstract from Unknown event, Asilomar, USA.
Groenink, L., & Olivier, B. (2003). Transgenic mice overexpressing corticotropin-releasing factor as an animal model for psychotic depression. 47-48. Abstract from Joint meeting of the Turkish and Dutch pharmacological societies.
van den Bergh, F. S., Groenink, L., & Olivier, B. (2003). Effects of methylphenidate on impulsivity of normal rats in an animal model for ADHD. 216. Abstract from 2nd Dutch Endo-Neuro-Psycho Meeting (7th Endo-Neuro-Meeting).
van Bogaert, M. J. V., Groenink, L., Oosting, R. S., & Olivier, B. (2003). Mouse strain differences in sensitivity towards anxiolytic drugs, a telemetric study. S24-S25. Abstract from 10th biennial meeting of the EBPS.
van Bogaert, M. J. V., Groenink, L., van der Gugten, J., & Olivier, B. (2003). Effects of stressful stimuli on physiological and autonomic parameters in three strains of mice: genetic background differences. Abstract from The Society for Neuroscience 33rd Annual Meeting Itinerary, New Orleans, U.S.A..
Groenink, L., de Graaff, M., & Olivier, B. (2003). Differential effects of anxiogenic drugs on acoustic startle response in mice. S39. Abstract from 10th biennial meeting of the EBPS.
van den Bergh, F. S., Groenink, L., Oosting, R. S., & Olivier, B. (2003). Effects of methylphenidate on impulsivity of rats in the five choice serial reaction time task. Abstract from The Society for Neuroscience 33rd Annual Meeting Itinerary, New Orleans, U.S.A..
Dirks, A., Groenink, L., Westphal, K. G. C., de Graaff, M., van der Gugten, J., Tuinstra, T., Herremans, A. H. J., & Olivier, B. (2003). Effects of fluvoxamine on behavior and HPA axis reactivity in transgenic mice overexpressing CRF. 168. Abstract from 2nd Dutch Endo-Neuro-Psycho Meeting (7th Endo-Neuro-Meeting).
Verdouw, P. M., de Jongh, R., Groenink, L., van der Gugten, J., & Olivier, B. (2003). Activatie van hersengebieden tijdens verschillende angstsituaties. Poster session presented at Figon-dag, Leiden.
Dirks, A., Groenink, L., Westphal, K. G. C., Olivier, J. D. A., Oppelaar-Verdouw, P. M., van der Gugten, J., Geyer, M. A., & Olivier, B. (2003). Improvement of startle gating deficits in transgenic mice overexpressing corticotropin-releasing factor by antipsychotic drugs. S41. Abstract from 10th biennial meeting of the EBPS.
Diergaarde, L., Gerrits, M. A. F. M., Groenink, L., van Ree, J. M., & Feenstra, M. G. (2003). Effects of neonatal excitotoxic lesions of the basolateral amygdala on behavioral flexibility in the rat. Abstract from Annual Neuroscience Meeting, New Orleans.
van den Bergh, F. S., Groenink, L., & Olivier, B. (2003). Dose-dependent effects of methylphenidate on performance of rats in the five choice serial reaction time tast. S36. Abstract from 10th biennial meeting of the EBPS.
Diergaarde, L., Groenink, L., Gerrits, M. A. F. M., & van Ree, J. M. (2003). Neonatal amygdala lesions in the rat: Effects on social behavior and cognition. Abstract from Summerschool Rudolf Magnus Institute of Neuroscience, Zeist.
2002
Scholarly publications
Dirks, A., Groenink, L., Schipholt, M. I., Van Der Gugten, J., Hijzen, T. H., Geyer, M. A., & Olivier, B. (2002). Reduced startle reactivity and plasticity in transgenic mice overexpressing corticotropin-releasing hormone. Biological Psychiatry, 51(7), 583-590. [DOI]
Pattij, T., Groenink, L., Oosting, R. S., Van der Gugten, J., Maes, R. A. A., & Olivier, B. (2002). GABAA-benzodiazepine receptor complex sensitivity in 5-HT1A receptor knockout mice on a 129/Sv background. European Journal of Pharmacology, 447(1), 67-74. [DOI]
Groenink, L., Dirks, A., Verdouw, P. M., lutje Schipholt, M., Veening, J. G., van der Gugten, J., & Olivier, B. (2002). HPA Axis dysregulation in mice overexpressing corticotropin releasing hormone. Biological Psychiatry, 51, 875-881.
de Jongh, R., Groenink, L., van der Gugten, J., & Olivier, B. (2002). The light-enhanced startle paradigm as a putative animal model for anxiety: effects of chlordiazepoxide, flesinoxan and fluvoxamine. Psychopharmacology, 159, 176-180.
Dirks, A., Fish, E. W., Kikusui, T., van der Gugten, J., Groenink, L., Olivier, B., & Miczek, K. A. (2002). Effects of corticotropin-releasing hormone on distress vocalizations and locomotion in maternally separated mouse pups. Pharmacology, Biochemistry and Behavior, 72, 993-999.
Dirks, A., Groenink, L., lutje Schipholt, M., van der Gugten, J., Hijzen, T. H., Geyer, M. A., & Olivier, B. (2002). Reduced startle reactivity and plasticity in transgenic mice overexpressing corticotropin-releasing hormone. Biological Psychiatry, 51, 583-590.
Dirks, A., Groenink, L., Bouwknecht, J. A., Hijzen, T. H., van der Gugten, J., Ronken, E., Verbeek, J. S., Veening, J. G., Dederen, P. J. W. C., Körösi, A., Schoolderman, L. F., Roubos, E. W., & Olivier, B. (2002). Overexpression of corticotropin-releasing hormone in transgenic mice and chronic stress-like autonomic and physiological alterations. European Journal of Neuroscience, 16, 1751-1760.
Dirks, A., Groenink, L., Verdouw, P. M., lutje Schipholt, M., van der Gugten, J., Hijzen, T. H., & Olivier, B. (2002). Behavioral analysis of transgenic mice overexpressing corticotropin-releasing hormone in paradigms emulating aspects of stress, anxiety, and depression. International Journal of Comparative Psychology, 14, 123-135.
Pattij, T., Groenink, L., Oosting, R. S., van der Gugten, J., Maes, R. A. A., & Olivier, B. (2002). GABA-A-benzodiazepine receptor complex sensitivity in 5-HT1A receptor knockout mice on a 129/Sv background. European Journal of Pharmacology, 447, 67-74.
Pattij, T., Groenink, L., Hijzen, T. H., Oosting, R. S., Maes, R. A. A., van der Gugten, J., & Olivier, B. (2002). Autonomic changes associated with enhanced anxiety in 5-HT1A receptor knockout mice. Neuropsychopharmacology, 27, 380-390.
Other output
Dirks, A., Groenink, L., Westphal, K. G. C., de Graaff, M., van der Gugten, J., Tuinstra, T., Herremans, A. H. J., & Olivier, B. (2002). Effects of fluvoxamine on behavior and HPA axis reactivity in transgenic mice overexpressing CRH. Abstract from Society for Neuroscience, 2002 CD-ROM, Washington, DC.
de Jongh, R., Groenink, L., van der Gugten, J., & Olivier, B. (2002). The effects of alpha-helical CRH on fear-potentiated versus light-enhanced startle. Abstract from Society for Neuroscience, 2002 CD-ROM, Washington, DC.
Pattij, T., van der Linde, J., Groenink, L., van der Gugten, J., Sarnyai, Z., & Olivier, B. (2002). Serotonin-1B receptor knockout mice display increased impulsive behavior in operant paradigms. Abstract from Society for Neuroscience, 2002 CD-ROM, Washington, DC.
Olivier, B., Groenink, L., & van der Gugten, J. (2002). 5-HT1A receptor knockout mice and anxiety: Is the GABAA-benzodiazepine receptor complex involved?. S153-S154. Abstract from 15th Congress of the European College of Neuropsychopharmacology.
Veening, J. G., Schoolderman, L. F., Körösi, A., Dederen, P. J. W. C., Dirks, A., Groenink, L., van der Gugten, J., Roubos, E. W., & Olivier, B. (2002). Transgenic mice overexpressing CRH reveal changed CRH and stress-related FOS - IR. Abstract from Society for Neuroscience, 2002 CD-ROM, Washington, DC.
2001
Scholarly publications
Dirks, A., de Jongh, R., Groenink, L., van der Gugten, J., Hijzen, T. H., & Olivier, B. (2001). Footshock-induced sensitization of the acoustic startle response in two strains of mice. Behavioural Brain Research, 123, 17-21.
Pattij, T., Hijzen, T. H., Groenink, L., Oosting, R. S., van der Gugten, J., Maes, R. A. A., Hen, R., & Olivier, B. (2001). Stress-induced hyperthermia in the 5-HT1A receptor knockout mouse is normal. Biological Psychiatry, 49, 569-574.
Dirks, A., Pattij, T., Bouwknecht, J. A., Westphal, T. T., Hijzen, T. H., Groenink, L., van der Gugten, J., Oosting, R. S., Hen, R., Geyer, M. A., & Olivier, B. (2001). 5-HT1B receptor knockout, but not 5-HT1A receptor knockout mice, show reduced startle reactivity and footshock-induced sensitization, as measured with the acoustic startle response. Behavioural Brain Research, 118, 169-178.
Other output
Dirks, A., Groenink, L., lutje Schipholt, M., Oppelaar-Verdouw, P. M., van der Gugten, J., Hijzen, T. H., Veening, J. G., & Olivier, B. (2001). Altered startle reactivity, prepulse inhibition and behavior in transgenic mice overexpressing corticotropin-releasing hormone. Abstract from 31th Annual Meeting of Society for Neuroscience Meeting.
Pattij, T., Groenink, L., van der Gugten, J., & Olivier, B. (2001). GABAA-BDZ receptor sensitivity is not changed in 5-HT1A R KO on a 129/Sv genetic background. Abstract from Neuroscience meeting 2001, San Diego, USA.
de Jongh, R., Groenink, L., van der Gugten, J., & Olivier, B. (2001). The light-enhanced startle paradigm as a putative animal model for anxiety; a pharmacological validation. Abstract from Neuroscience meeting 2001, San Diego, USA.
de Jongh, R., Groenink, L., van der Gugten, J., & Olivier, B. (2001). The effects of CRH-overexpression on context and auditory cue conditioning. 149. Abstract from 5th Dutch Endo-Neuro-Psycho meeting, Doorwerth, Netherlands, Netherlands.
de Jongh, R., Groenink, L., van der Gugten, J., & Olivier, B. (2001). The effects of chlordiazepoxide, flesinoxan and fluvoxamine on the light-enhanced startle reflex in rats. Abstract from Farmacologiedagen 2001.
Groenink, L., Dirks, A., Oppelaar-Verdouw, P. M., lutje Schipholt, M., van der Gugten, J., & Olivier, B. (2001). HPA-axis dysregulation in CRH-overexpressing mice. 116. Abstract from 5th Dutch Endo-Neuro-Psycho meeting, Doorwerth, Netherlands, Netherlands.
Pattij, T., Groenink, L., van der Gugten, J., & Olivier, B. (2001). 5-HT1A receptor KO mice display a context-dependent anxiety. Abstract from Farmacologiedagen 2001.
Dirks, A., Groenink, L., lutje Schipholt, M., van der Gugten, J., Hijzen, T. H., & Olivier, B. (2001). Reduced startle reactivity and plasticity in transgenic mice overexpressing corticotropin-releasing hormone. 116. Abstract from 5th Dutch Endo-Neuro-Psycho meeting, Doorwerth, Netherlands, Netherlands.
Pattij, T., Groenink, L., van der Gugten, J., & Olivier, B. (2001). Serotonin 1A receptor knockout mice display a context-dependent enhanced anxiety. 150. Abstract from 5th Dutch Endo-Neuro-Psycho meeting, Doorwerth, Netherlands, Netherlands.
2000
Scholarly publications
Groenink, L., Joordens, R. J. E., Hijzen, T. H., Dirks, A., & Olivier, B. (2000). Infusion of flesinoxan into the amygdala blocks the fear-potentiated startle. NeuroReport, 11(10), 2285-2288.
Other output
Dirks, A., Bouwknecht, J. A., Ronken, E., Oosting, R. S., Hijzen, T. H., Groenink, L., van der Gugten, J., & Olivier, B. (2000). Overexpression of CRH results in altered physiology as determined by radiotelemetry. 47. Abstract from Unknown event, Asilomar, USA.
Pattij, T., Hijzen, T. H., Oosting, R. S., Groenink, L., van der Gugten, J., & Olivier, B. (2000). 5-HT1A receptor knockout mice display a normal stress-induced hyperthermia response. 54. Abstract from Unknown event, Asilomar, USA.
Groenink, L., Oppelaar-Verdouw, P. M., Westphal, T. T., van der Gugten, J., & Olivier, B. (2000). Repeated restraint stress induces long lasting changes in basal plasma corticosterone levels and behaviour in rats. Abstract from 3rd World Congress on Stress, Dublin.
Pattij, T., Hijzen, T. H., Groenink, L., & Oosting, R. S. (2000). Effects of flesinoxan, mCPP and diazepam on stress-induced hyperthermia and heart rate in 5-HT1A receptor knockout mice. 395. Abstract from Unknown event, Asilomar, USA.
Geyer, M. A., Pattij, T., Hijzen, T. H., Groenink, L., Dirks, A., van der Gugten, J., & Olivier, B. (2000). Startle responsivity in mice lacking the 5-HT1A receptor. 395. Abstract from Unknown event, Asilomar, USA.
Pattij, T., Hijzen, T. H., Groenink, L., Dirks, A., van der Gugten, J., & Olivier, B. (2000). Startle reactivity and startle plasticity are unaffected in serotonin 1A receptor knockout mice. SA37. Abstract from Unknown event, Asilomar, USA.
1999
Other output
Schlotter, R., Groenink, L., Westphal, T. T., Hijzen, T. H., van der Gugten, J., & Olivier, B. (1999). The forced swimming test: effects of different waterdepths. 139. Abstract from Unknown event, Asilomar, USA.
Menzen, G. H., Schlotter, R., Groenink, L., Hijzen, T. H., & Olivier, B. (1999). Effects of ageing, gender and CRF over-expression on performance and velocity in a continuous alternation task in the T-maze. 40. Abstract from 19th Low Countries Meeting, University of Nijmegen, Nijmegen.
Compaan, J. C., Dederen, P. J. W. C., Groenink, L., Hijzen, T. H., van der Gugten, J., Oosting, R. S., Ronken, E., Olivier, B., & Veening, J. G. (1999). Restraint stress enhances CRH and CRH-R1 mRNA in rat brain. Abstract from Neuroscience Meeting, Miami, Miami.
1998
Scholarly publications
Groenink, L., Schlotter, R., Oppelaar-Verdouw, P. M., Hijzen, T. H., van der Gugten, J., & Olivier, B. (1998). Dexamethasone suppression test - a tool for studying "depression" in rats. Fundamental and Clinical Pharmacology, 12, 107-107.
1997
Scholarly publications
Compaan, J. C., Groenink, L., van der Gugten, J., Maes, R. A. A., & Olivier, B. (1997). Flesinoxan treatment reduces hippocampal 5-HT1A receptor mRNA independent of high plasma corticosterone levels. Neuroscience, 23, 651-651.
Compaan, J. C., Groenink, L., van der Gugten, J., Maes, R. A. A., & Olivier, B. (1997). Pretreatment with 5-HT1A receptor agonist flesinoxan attenuates for protein in rat hypothalamus. European Journal of Pharmacology, 324, 161-168.
Groenink, L., van der Gugten, J., Compaan, J. C., Maes, R. A. A., & Olivier, B. (1997). Flesinoxan pretreatment differentially affects corticosterone, prolactin and behavioural responses to a flesinoxan challenge. Psychopharmacology, 131(1), 93-100.
Professional publications
Compaan, J. C., Groenink, L., van der Gugten, J., & Olivier, B. (1997). Pretreatment with 5-HT1A receptor agonist flesionoxan attenuates fos-immunoreactivity in the hypothala-mus, but not in limbic areas of the rat brain. In Pharmacological Meeting Lunteren 20 - 21 Februari
1996
Scholarly publications
Compaan, J. C., Groenink, L., Van der Gugten, J., Maes, R. A. A., & Olivier, B. (1996). 5-HT(1A) receptor agonist flesinoxan enhances Fos immunoreactivity in rat central amygdala, bed nucleus of the stria terminalis and hypothalamus. European Journal of Neuroscience, 8(11), 2340-2347. [DOI] [Portal]
Groenink, L., Mos, J., Van Der Gugten, J., & Olivier, B. (1996). The 5-HT(1A) receptor is not involved in emotional stress-induced rises in stress hormones. Pharmacology Biochemistry and Behavior, 55(2), 303-308. [DOI]
Groenink, L., Van Der Gugten, J., Zethof, T. J. J., van der Heyden, J. A. M., & Olivier, B. (1996). Neuroendocrine effects of diazepam and flesinoxan in the stress-induced hyperthermia test in mice. Pharmacology Biochemistry and Behavior, 54(1), 249-254. [DOI]
Olivier, B., Groenink, L., & Molewijk, H. E. (1996). Experimental models of human anxiety - efficacy of antipanic agents. European Neuropsychopharmacology, 4, 268-270.
Groenink, L. (1996). 5-HT1A receptors, stress and anxiety - neuroendocrine and behavioural interrelationships. [Doctoral thesis 1 (Research UU / Graduation UU), Universiteit Utrecht].
Groenink, L., Mos, J., van der Gugten, J., & Olivier, B. (1996). The 5-HT1A receptor is not involved in stress-induced rises in stress hormones. Pharmacology, Biochemistry and Behavior, 55, 303-308.
Compaan, J. C., Groenink, L., van der Gugten, J., Maes, R. A. A., & Olivier, B. (1996). 5HT1A Receptor agonist flesinoxan enhances FoS immunoreactivity in rat central amygdala, bed nucleus of the Stria terminalis and hypothalamus. European Journal of Neuroscience, 8, 2340-2347.
Professional publications
Olivier, B., Molewijk, E., Groenink, L., Joordens, R. J. E., Zethof, T. J. J., & Mos, J. (1996). Potential animal models for the study of anti-panic and anti-phobic treatments. Advances in the neurobiology of anxiety disorders, 83-105.
Other output
Groenink, L., van der Gugten, J., Long, S. K., & Olivier, B. (1996). Neuroendocrine effects induced by 5-HT1A receptor agonists are mediated by centrally located postsynaptic 5-HT1A receptors. 2014. Abstract from Unknown event, Asilomar, USA.
1995
Scholarly publications
1994
Scholarly publications
Groenink, L., van der Gugten, J., Zethof, T., Van Der Heyden, J., & Olivier, B. (1994). Stress-induced hyperthermia in mice: Hormonal correlates. Physiology and Behavior, 56(4), 747-749. [DOI]
Groenink, L., Van Der Gugten, J., Mos, J., Maes, R. A. A., & Olivier, B. (1994). (S)-UH301, a silent 5-HT(1A) receptor antagonist, enhances plasma cortiocosterone levels in the rat. Life Sciences, 55(5), 99-103. [DOI]