Publications
2022
Scholarly publications
Exel, C. E., Halasa, T., Koop, G., Steeneveld, W., Lam, T. J. G. M., Benedictus, L., & Gussmann, M. (2022). A stochastic modelling approach to determine the effect of diverse Staphylococcus aureus strains on the economic and epidemiological outcomes of mastitis intervention strategies in dairy cattle. Preventive Veterinary Medicine, 199, 105566. https://doi.org/10.1016/j.prevetmed.2021.105566
2021
Scholarly publications
Robbers, L., Koets, A. P., Benedictus, L., Nielen, M., & Jorritsma, R. (2021). Survey on Colostrum Management by Dairy Farmers in the Netherlands. Frontiers in Veterinary Science, 8, [656391]. https://doi.org/10.3389/fvets.2021.656391
Fisch, A., Reynisson, B., Benedictus, L., Nicastri, A., Vasoya, D., Morrison, W. I., Buus, S., Ferreira, B. R., Santos, I. K. F. D. M., Ternette, N., Connelley, T., & Nielsen, M. (2021). Integral Use of Immunopeptidomics and Immunoinformatics for the Characterization of Antigen Presentation and Rational Identification of BoLA-DR–Presented Peptides and Epitopes. The Journal of Immunology, 206(10), 2489-2497. https://doi.org/10.4049/jimmunol.2001409
Edmans, M. D., Connelley, T. K., Jayaraman, S., Vrettou, C., Vordermeier, M., Mak, J. Y. W., Liu, L., Fairlie, D. P., Maze, E. A., Chrun, T., Klenerman, P., Eckle, S. B. G., Tchilian, E., & Benedictus, L. (2021). Identification and Phenotype of MAIT Cells in Cattle and Their Response to Bacterial Infections. Frontiers in Immunology, 12, [627173]. https://doi.org/10.3389/fimmu.2021.627173
2020
Scholarly publications
Benedictus, L., Steinbach, S., Holder, T., Bakker, D., Vrettou, C., Morrison, W. I., Vordermeier, M., & Connelley, T. (2020). Hydrophobic Mycobacterial Antigens Elicit Polyfunctional T Cells in Mycobacterium bovis Immunized Cattle: Association With Protection Against Challenge? Frontiers in Immunology, 11, [588180]. https://doi.org/10.3389/fimmu.2020.588180
Callaby, R., Kelly, R., Mazeri, S., Egbe, F., Benedictus, L., Clark, E., Doeschl-Wilson, A., Bronsvoort, B., Salavati, M., & Muwonge, A. (2020). Genetic Diversity of Cameroon Cattle and a Putative Genomic Map for Resistance to Bovine Tuberculosis. Frontiers in Genetics, 11, [550215]. https://doi.org/10.3389/fgene.2020.550215
Vrieling, M., Tuffs, S. W., Yebra, G., van Smoorenburg, M. Y., Alves, J., Pickering, A. C., Park, J. Y., Park, N., Heinrichs, D. E., Benedictus, L., Connelley, T., Seo, K. S., McCormick, J. K., & Fitzgerald, J. R. (2020). Population Analysis of Staphylococcus aureus Reveals a Cryptic, Highly Prevalent Superantigen SElW That Contributes to the Pathogenesis of Bacteremia. mBio, 11(5), [ e02082-20]. https://doi.org/10.1128/mBio.02082-20
Hoekstra, J., Zomer, A. L., Rutten, V. P. M. G., Benedictus, L., Stegeman, A., Spaninks, M. P., Bennedsgaard, T. W., Biggs, A., De Vliegher, S., Mateo, D. H., Huber-Schlenstedt, R., Katholm, J., Kovács, P., Krömker, V., Lequeux, G., Moroni, P., Pinho, L., Smulski, S., Supré, K., ... Koop, G. (2020). Genomic analysis of European bovine Staphylococcus aureus from clinical versus subclinical mastitis. Scientific Reports, 10(1), [18172]. https://doi.org/10.1038/s41598-020-75179-2
2019
Scholarly publications
Hoekstra, J., Rutten, V. P. M. G., Lam, T. J. G. M., van Kessel, K., Spaninks, M. P., Stegeman, J. A., Benedictus, L., & Koop, G. (2019). Activation of a Bovine Mammary Epithelial Cell Line by Ruminant-Associated Staphylococcus aureus is Lineage Dependent. Microorganisms, 12(7), [688]. https://doi.org/10.3390/microorganisms7120688
Hoekstra, J., Rutten, V. P. M. G., van den Hout, M., Spaninks, M. P., Benedictus, L., & Koop, G. (2019). Differences between Staphylococcus aureus lineages isolated from ovine and caprine mastitis but not between isolates from clinical or subclinical mastitis. Journal of Dairy Science, 102(6), 5430-5437. https://doi.org/10.3168/jds.2018-16196
Benedictus, L., Ravesloot, L., Poppe, K., Daemen, I., Boerhout, E., van Strijp, J., Broere, F., Rutten, V., Koets, A., & Eisenberg, S. (2019). Immunization of young heifers with staphylococcal immune evasion proteins before natural exposure to Staphylococcus aureus induces a humoral immune response in serum and milk. BMC Veterinary Research, 15, [15]. https://doi.org/10.1186/s12917-018-1765-9
2018
Scholarly publications
Hoekstra, J., Rutten, V., Sommeling, L., van Werven, T., Spaninks, M., Duim, B., Benedictus, L., & Koop, G. (2018). High Production of LukMF' in Staphylococcus aureus Field Strains Is Associated with Clinical Bovine Mastitis. Toxins, 10(5), [200]. https://doi.org/10.3390/toxins10050200
2016
Scholarly publications
Vrieling, M., Boerhout, E. M., van Wigcheren, G. F., Koymans, K. J., Mols-Vorstermans, T. G., de Haas, C. J. C., Aerts, P. C., Daemen, I. J. J. M., van Kessel, K. P. M., Koets, A. P., Rutten, V. P. M. G., Nuijten, P. J. M., van Strijp, J. A. G., & Benedictus, L. (2016). LukMF' is the major secreted leukocidin of bovine Staphylococcus aureus and is produced in vivo during bovine mastitis. Scientific Reports, 6, [37759]. https://doi.org/10.1038/srep37759
Eisenberg, S. W. F., Boerhout, E. M., Ravesloot, L., Daemen, A. J. J. M., Benedictus, L., Rutten, V. P. M. G., & Koets, A. P. (2016). Diurnal differences in milk composition and its influence on in vitro growth of Staphylococcus aureus and Escherichia coli in bovine quarter milk. Journal of Dairy Science, 99(7), 5690–5700. https://doi.org/10.3168/jds.2015-10757
Benedictus, L., Rutten, V. P. M. G., & Koets, A. P. (2016). Pregnancy boosts vaccine-induced Bovine Neonatal Pancytopenia-associated alloantibodies. Vaccine, 34(8), 1002-1005. https://doi.org/10.1016/j.vaccine.2016.01.013
2015
Scholarly publications
Boerhout, E., Vrieling, M., Benedictus, L., Daemen, I., Ravesloot, L., Rutten, V., Nuijten, P., van Strijp, J., Koets, A., & Eisenberg, S. (2015). Immunization routes in cattle impact the levels and neutralizing capacity of antibodies induced against S. aureus immune evasion proteins. Veterinary Research, 46(1), [115]. https://doi.org/10.1186/s13567-015-0243-7
Benedictus, L., Luteijn, R. D., Otten, H., Jan Lebbink, R., van Kooten, P. J. S., Wiertz, E. J. H. J., Rutten, V. P. M. G., & Koets, A. P. (2015). Pathogenicity of Bovine Neonatal Pancytopenia-associated vaccine-induced alloantibodies correlates with Major Histocompatibility Complex class I expression. Scientific Reports, 5, [12748]. https://doi.org/10.1038/srep12748
Benedictus, L., Koets, A. P., & Rutten, V. P. M. G. (2015). The role of placental MHC class I expression in immune-assisted separation of the fetal membranes in cattle. Journal of Reproductive Immunology, 112, 11-19. https://doi.org/10.1016/j.jri.2015.05.003
Benedictus, L. (2015). Bovine materno-fetal alloimmune mediated disorders: MHC class I (in)compatibility in Retained Fetal Membranes and Bovine Neonatal Pancytopenia. Uitgeverij BOXPress. https://dspace.library.uu.nl/handle/1874/310576
2014
Scholarly publications
Benedictus, L., Otten, H. G., van Schaik, G., van Ginkel, W. G., Heuven, H. C., Nielen, M., Rutten, V. P., & Koets, A. P. (2014). Bovine Neonatal Pancytopenia is a heritable trait of the dam rather than the calf and correlates with the magnitude of vaccine induced maternal alloantibodies not the MHC haplotype. Veterinary Research, 45, [45:129]. https://doi.org/10.1186/s13567-014-0129-0
2013
Scholarly publications
Benedictus, L., Koets, A. P., Kuijpers, F. H. J., Joosten, I., van Eldik, P., & Heuven, H. C. M. (2013). Heritable and non-heritable genetic effects on retained placenta in Meuse-Rhine-Yssel cattle. Animal Reproduction Science, 137(1-2), 1-7. https://doi.org/10.1016/j.anireprosci.2012.12.006
Other output
Benedictus, L., Rutten, V., Nielen, M., van Schaik, G., Heuven, H., & Koets, A. (2013). Bovine Neonatal Pancytopenia is a heritable trait for dams. Poster session presented at 10th International Veterinary Immunology Symposium (IVIS), Milan, Netherlands.
https://dspace.library.uu.nl/bitstream/handle/1874/415537/LB130812_IVIS_Poster_BNP4.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/415537/LB130812_IVIS_Poster_BNP4.pdf?sequence=1
2012
Scholarly publications
Benedictus, L., Thomas, A. J., Jorritsma, R., Davies, C. J., & Koets, A. P. (2012). Two-Way Calf to Dam Major Histocompatibility Class I Compatibility Increases Risk for Retained Placenta in Cattle. American Journal of Reproductive Immunology, 67(6), 179-183. https://doi.org/10.1111/j.1600-0897.2011.01085.x
Other output
Benedictus, L., Koets, A. P., van Eldik, P., & Heuven, H. C. M. (2012). Retained placenta in MRIJ cattle is affected by heritable and non-heritable factors. Poster session presented at Unknown event.
https://dspace.library.uu.nl/bitstream/handle/1874/315457/Poster%2520-%2520Retained%2520placenta%2520in%2520MRIJ%2520cattle....doc?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/315457/Poster%2520-%2520Retained%2520placenta%2520in%2520MRIJ%2520cattle....doc?sequence=1
2011
Scholarly publications
Benedictus, L., Jorritsma, R., Vos, P. L. A. M., & Koets, A. P. (2011). Chemotactic activity of cotyledons for mononuclear leukocytes related to occurrence of retained placenta in dexamethasone induced parturition in cattle. Theriogenology, 76, 802-809.