Publications

2024

Scholarly publications

Global Lung Function Initiative FENO Task Force, Högman, M., Bowerman, C., Chavez, L., Dressel, H., Malinovschi, A., Radtke, T., Stanojevic, S., Steenbruggen, I., Turner, S., Dinh-Xuan, A. T., Amaral, R., Backer, V., Cameli, P., Duong-Quy, S., Leung, T. F., Gehring, U., Hall, G., Hong, S. J., ... Vinnikov, D. (2024). ERS technical standard: Global Lung Function Initiative reference values for exhaled nitric oxide fraction (FENO50). European Respiratory Journal , 63(1), Article 2300370. https://doi.org/10.1183/13993003.00370-2023
https://research-portal.uu.nl/ws/files/246130105/Eur_Respir_J-2024-H_gman-2300370.pdf
Jacobs, J. H., Strak, M., Velders, G. JM., Zorn, J., Hogerwerf, L., Simões, M., Mijnen-Visser, S., Wesseling, J., Gerlofs-Nijland, M. E., Smit, L. AM., Vermeulen, R., van der Zee, S., Mughini-Gras, L., & Stafoggia, M. (2024). Short-term exposure to ambient air pollution and severe COVID-19: mortality and hospital admission to COVID-19 in the Netherlands from february to december 2020. Environmental Advances, 17, Article 100592. https://doi.org/10.1016/j.envadv.2024.100592
https://research-portal.uu.nl/ws/files/242961720/1-s2.0-S2666765724001108-main.pdf
Bossers, A., de Rooij, M. M., van Schothorst, I., Velkers, F. C., & Smit, L. A. (2024). Detection of airborne wild waterbird-derived DNA demonstrates potential for transmission of avian influenza virus via air inlets into poultry houses, the Netherlands, 2021 to 2022. Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 29(40), Article 2400350. https://doi.org/10.2807/1560-7917.ES.2024.29.40.2400350
https://research-portal.uu.nl/ws/files/241605844/eurosurv-29-40-3.pdf
Cornu Hewitt, B., Bossers, A., van Kersen, W., de Rooij, M. M. T., & Smit, L. A. M. (2024). Associations between acquired antimicrobial resistance genes in the upper respiratory tract and livestock farm exposures: a case-control study in COPD and non-COPD individuals. Journal of Antimicrobial Chemotherapy. Advance online publication. https://doi.org/10.1093/jac/dkae335
Odendaal, M.-L., de Steenhuijsen Piters, W. A. A., Franz, E., Chu, M. L. J. N., Groot, J. A., van Logchem, E. M., Hasrat, R., Kuiling, S., Pijnacker, R., Mariman, R., Trzciński, K., van der Klis, F. R. M., Sanders, E. A. M., Smit, L. A. M., Bogaert, D., & Bosch, T. (2024). Host and environmental factors shape upper airway microbiota and respiratory health across the human lifespan. Cell, 187(17), 4571-4585.e15. https://doi.org/10.1016/j.cell.2024.07.008
https://research-portal.uu.nl/ws/files/237164602/PIIS0092867424007682.pdf
Simões, M., Zorn, J., Hogerwerf, L., Velders, G. J. M., Portengen, L., Gerlofs-Nijland, M., Dijkema, M., Strak, M., Jacobs, J., Wesseling, J., de Vries, W. J., Mijnen-Visser, S., Smit, L. A. M., Vermeulen, R., & Mughini-Gras, L. (2024). Outdoor air pollution as a risk factor for testing positive for SARS-CoV-2: A nationwide test-negative case-control study in the Netherlands. International Journal of Hygiene and Environmental Health, 259, Article 114382. https://doi.org/10.1016/j.ijheh.2024.114382
https://dspace.library.uu.nl/bitstream/handle/1874/451723/1-s2.0-S1438463924000634-main.pdf?sequence=1
Santman-Berends, I. M. G. A., Schaik, G. V., Augustijn-Schretlen, M., Bisschop, I. P. I. H., Rond, J. D., Meijer, P. A., Heijden, H. M. J. F. V. D., Velkers, F. C., Koopmans, M. P. G., Poel, W. H. M. V. D., Smit, L. A. M., Stegeman, A. J. A., Sikkema, R. S., Munnink, B. B. O., Honing, R. W. H. D., & Molenaar, R.-J. (2024). Effectiveness of Passive and Active Surveillance for Early Detection of SARS-CoV-2 in Mink during the 2020 Outbreak in the Netherlands. Transboundary and emerging diseases, 2024, Article 4793475. https://doi.org/10.1155/2024/4793475
https://dspace.library.uu.nl/bitstream/handle/1874/438391/4793475.pdf?sequence=1
de Geus, Y., Scherpenisse, P., Smit, L. A. M., Bossers, A., Stegeman, J. A., Benedictus, L., Spieß, L., & Koop, G. (2024). Total bacterial count and somatic cell count in bulk and individual goat milk around kidding: two longitudinal observational studies. Journal of Dairy Science, 107(8), 5427-5437. https://doi.org/10.3168/jds.2023-24574
https://research-portal.uu.nl/ws/files/233889638/PIIS0022030224007422.pdf
Zorn, J., Simões, M., Velders, G. J. M., Gerlofs-Nijland, M., Strak, M., Jacobs, J., Dijkema, M. B. A., Hagenaars, T. J., Smit, L. A. M., Vermeulen, R., Mughini-Gras, L., Hogerwerf, L., & Klinkenberg, D. (2024). Effects of long-term exposure to outdoor air pollution on COVID-19 incidence: A population-based cohort study accounting for SARS-CoV-2 exposure levels in the Netherlands. Environmental Research, 252(Part 1), 1-13. Article 118812. https://doi.org/10.1016/j.envres.2024.118812, https://doi.org/10.1016/j.envres.2024.118812
https://dspace.library.uu.nl/bitstream/handle/1874/437788/1-s2.0-S0013935124007163-main.pdf?sequence=1
Munk, P., Yang, D., Röder, T., Maier, L., Petersen, T. N., Duarte, A. S. R., Clausen, P. T. L. C., Brinch, C., Van Gompel, L., Luiken, R., Wagenaar, J. A., Schmitt, H., Heederik, D. J. J., Mevius, D. J., Smit, L. A. M., Bossers, A., & Aarestrup, F. M. (2024). The European livestock resistome. mSystems, 9(4), Article e0132823. https://doi.org/10.1128/msystems.01328-23
https://dspace.library.uu.nl/bitstream/handle/1874/438370/munk-et-al-2024-the-european-livestock-resistome.pdf?sequence=1
Hewitt, B. C., Smit, L. A. M., Kersen, W. V., Wouters, I. M., Heederik, D. J. J., Kerckhoffs, J., Hoek, G., & Rooij, M. M. T. D. (2024). Residential exposure to microbial emissions from livestock farms: Implementation and evaluation of land use regression and random forest spatial models. Environmental Pollution, 346, 123590. Article 123590. https://doi.org/10.1016/j.envpol.2024.123590
https://dspace.library.uu.nl/bitstream/handle/1874/436875/1-s2.0-S026974912400304X-main.pdf?sequence=1
van Kersen, W., de Rooij, M. M. T., Portengen, L., Diez, N. S., Pieterson, I., Tewis, M., Boer, J. M. A., Koppelman, G., Vonk, J. M., Vermeulen, R., Gehring, U., Huss, A., & Smit, L. A. M. (2024). Impact of COVID-19 containment measures on perceived health and health-protective behavior: a longitudinal study. Scientific Reports, 14(1), 1-9. Article 419. https://doi.org/10.1038/s41598-023-50542-1
https://dspace.library.uu.nl/bitstream/handle/1874/435271/s41598-023-50542-1.pdf?sequence=1
de Rooij, M. M. T., Erbrink, H. J., Smit, L. A. M., Wouters, I. M., Hoek, G., & Heederik, D. J. J. (2024). Short-term residential exposure to endotoxin emitted from livestock farms in relation to lung function in non-farming residents. Environmental Research, 243, Article 117821. https://doi.org/10.1016/j.envres.2023.117821
https://dspace.library.uu.nl/bitstream/handle/1874/435014/1-s2.0-S0013935123026257-main.pdf?sequence=1
Sandoval-Diez, N., Smit, L. A. M., Boer, J. M. A., de Rooij, M. M. T., Koppelman, G. H., van Kersen, W., Vonk, J. M., Vermeulen, R., Gehring, U., & Huss, A. (2024). Associations of Anti–COVID-19 Measures and Lifestyle Changes During the COVID-19 Pandemic With Sleep Patterns in the Netherlands: A Longitudinal Study. American Journal of Epidemiology, 193(4), 646–659. https://doi.org/10.1093/aje/kwad228
https://dspace.library.uu.nl/bitstream/handle/1874/438071/kwad228.pdf?sequence=1

2023

Scholarly publications

Yzermans, C. J., Moleman, Y. P., Spreeuwenberg, P., Nielen, M. M. J., Dückers, M. L. A., Smit, L. A. M., & Baliatsas, C. (2023). Risk of pneumonia in the vicinity of goat farms: a comparative assessment of temporal variation based on longitudinal health data. Pneumonia, 15(1), Article 13. https://doi.org/10.1186/s41479-023-00115-7
https://dspace.library.uu.nl/bitstream/handle/1874/431029/s41479-023-00115-7.pdf?sequence=1
Lotterman, A., Baliatsas, C., de Rooij, M. M. T., Huss, A., Jacobs, J., Dückers, M., Boender, G. J., McCarthy, C., Heederik, D., Hagenaars, T. J., Yzermans, C. J., & Smit, L. A. M. (2023). Increased risk of pneumonia amongst residents living near goat farms in different livestock-dense regions in the Netherlands. PLoS One, 18(7), Article e0286972. https://doi.org/10.1371/journal.pone.0286972
https://dspace.library.uu.nl/bitstream/handle/1874/429321/journal.pone.0286972.pdf?sequence=1
Rittscher, A. E., Vlasblom, A. A., Duim, B., Scherpenisse, P., van Schothorst, I. J., Wouters, I. M., Van Gompel, L., & Smit, L. A. M. (2023). A comparison of passive and active dust sampling methods for measuring airborne methicillin-resistant Staphylococcus aureus in pig farms. Annals of Work Exposures and Health, 67(8), 1004-1010. Article wxad033. https://doi.org/10.1093/annweh/wxad033
https://dspace.library.uu.nl/bitstream/handle/1874/431572/wxad033.pdf?sequence=1
Fakunle, A. G., Jafta, N., Bossers, A., Wouters, I. M., Kersen, W. V., Naidoo, R. N., & Smit, L. A. M. (2023). Childhood lower respiratory tract infections linked to residential airborne bacterial and fungal microbiota. Environmental Research, 231(Part 1), 1-12. Article 116063. https://doi.org/10.1016/j.envres.2023.116063
https://dspace.library.uu.nl/bitstream/handle/1874/429608/1_s2.0_S0013935123008551_main.pdf?sequence=1
Smit, L. A. M., Jacobs, J., da Silva, J., Heederik, D., van Rooy, F. G., Portengen, L., & Houba, R. (2023). Exposure to soluble platinum salts in precious metal refinery workers over a 17-year period. Annals of Work Exposures and Health, 67(6), 720-730. Article wxad023. https://doi.org/10.1093/annweh/wxad023
https://dspace.library.uu.nl/bitstream/handle/1874/429349/wxad023.pdf?sequence=1
Fakunle, A. G., Jafta, N., Okekunle, A. P., Smit, L. A. M., & Naidoo, R. N. (2023). Exposure-response relationship of residential dampness and mold damage with severe lower respiratory tract infections among under-five children in Nigeria. Environmental Epidemiology, 7(2), 1-7. Article e247. https://doi.org/10.1097/EE9.0000000000000247
https://dspace.library.uu.nl/bitstream/handle/1874/428037/Exposure_response_relationship_of_residential.5.pdf?sequence=1
de Rooij, M. M. T., Sikkema, R. S., Bouwknegt, M., de Geus, Y., Stanoeva, K. R., Nieuwenweg, S., van Dam, A. S. G., Raben, C., Dohmen, W., Heederik, D., Reusken, C., Meijer, A., Koopmans, M. P. G., Franz, E., & Smit, L. A. M. (2023). A comprehensive sampling study on SARS-CoV-2 contamination of air and surfaces in a large meat processing plant experiencing COVID-19 clusters in June 2020. Journal of Occupational and Environmental Medicine, 65(4), E227-E233. https://doi.org/10.1097/JOM.0000000000002785
https://dspace.library.uu.nl/bitstream/handle/1874/429483/A_Comprehensive_Sampling_Study_on_SARS_CoV_2.17.pdf?sequence=1
Kiss, P., de Rooij, M. M. T., Koppelman, G. H., Boer, J., Vonk, J. M., Vermeulen, R., Hogerwerf, L., Sterk, H. A. M., Huss, A., Smit, L. A. M., & Gehring, U. (2023). Residential exposure to livestock farms and lung function in adolescence - The PIAMA birth cohort study. Environmental Research, 219, Article 115134. https://doi.org/10.1016/j.envres.2022.115134
https://dspace.library.uu.nl/bitstream/handle/1874/426740/1_s2.0_S0013935122024616_main.pdf?sequence=1

2022

Scholarly publications

Fakunle, A. G., Jafta, N., Smit, L. A. M., & Naidoo, R. N. (2022). Indoor bacterial and fungal aerosols as predictors of lower respiratory tract infections among under-five children in Ibadan, Nigeria. BMC Pulmonary Medicine, 22(1), Article 471. https://doi.org/10.1186/s12890-022-02271-w
https://dspace.library.uu.nl/bitstream/handle/1874/424982/s12890_022_02271_w_1_.pdf?sequence=1
Kwok, K. T. T., de Rooij, M. M. T., Messink, A. B., Wouters, I. M., Smit, L. A. M., Cotten, M., Heederik, D. J. J., Koopmans, M. P. G., & Phan, M. V. T. (2022). Establishing farm dust as a useful viral metagenomic surveillance matrix. Scientific Reports, 12(1), 1-14. Article 16308. https://doi.org/10.1038/s41598-022-20701-x
https://dspace.library.uu.nl/bitstream/handle/1874/423191/s41598_022_20701_x.pdf?sequence=1
Kannekens-Jager, M. M., de Rooij, M. M. T., de Groot, Y., Biesbroeck, E., de Jong, M. K., Pijnacker, T., Smit, L. A. M., Schuurman, N., Broekhuizen-Stins, M. J., Zhao, S., Duim, B., Langelaar, M. F. M., Stegeman, A., Kooistra, H. S., Radstake, C., Egberink, H. F., Wagenaar, J. A., & Broens, E. M. (2022). SARS-CoV-2 infection in dogs and cats is associated with contact to COVID-19 positive household members. Transboundary and emerging diseases, 69(6), 4034-4040. https://doi.org/10.1111/tbed.14713
https://dspace.library.uu.nl/bitstream/handle/1874/431338/Transbounding_Emerging_Dis_-_2022_-_Kannekens_Jager.pdf?sequence=1
van Kersen, W., Bossers, A., de Steenhuijsen Piters, W. A. A., de Rooij, M. M. T., Bonten, M., Fluit, A. C., Heederik, D., Paganelli, F. L., Rogers, M., Viveen, M., Bogaert, D., Leavis, H. L., & Smit, L. A. M. (2022). Air pollution from livestock farms and the oropharyngeal microbiome of COPD patients and controls. Environment international, 169, 1-9. Article 107497. https://doi.org/10.1016/j.envint.2022.107497
https://dspace.library.uu.nl/bitstream/handle/1874/423606/1_s2.0_S016041202200424X_main.pdf?sequence=1
Wolters, W. J., Rooij, M. M. T. D., Molenaar, R. J., Rond, J. D., Vernooij, J., Meijer, P. A., Munnink, B. B. O., Sikkema, R., Spek, A. N. V. D., Spierenburg, M. A. H., Honing, R. H. . V., VanderPoel, W., Koopmans, M., Stegeman, A., Smit, L. AM., Augustijn-Schretlen, M., & Velkers, F. (2022). Manifestation of SARS-CoV-2 Infections in Mink Related to Host-, Virus- and Farm-Associated Factors, The Netherlands 2020. Viruses, 14(8), 1-20. Article 1754. https://doi.org/10.3390/v14081754
https://dspace.library.uu.nl/bitstream/handle/1874/422629/viruses_14_01754_v2.pdf?sequence=1
Wallinga, D., Smit, L. A. M., Davis, M. F., Casey, J. A., & Nachman, K. E. (2022). A Review of the Effectiveness of Current US Policies on Antimicrobial Use in Meat and Poultry Production. Current environmental health reports, 9(2), 339-354. https://doi.org/10.1007/s40572-022-00351-x
https://dspace.library.uu.nl/bitstream/handle/1874/420694/Wallinga2022_Article_AReviewOfTheEffectivenessOfCur.pdf?sequence=1
Yang, D., Heederik, D. J. J., Scherpenisse, P., Van Gompel, L., Luiken, R. E. C., Wadepohl, K., Skarżyńska, M., Van Heijnsbergen, E., Wouters, I. M., Greve, G. D., Jongerius-Gortemaker, B. G. M., Tersteeg-Zijderveld, M., Portengen, L., Juraschek, K., Fischer, J., Zając, M., Wasyl, D., Wagenaar, J. A., Mevius, D. J., ... Schmitt, H. (2022). Antimicrobial resistance genes aph(3')-III, erm(B), sul2 and tet(W) abundance in animal faeces, meat, production environments and human faeces in Europe. Journal of Antimicrobial Chemotherapy, 77(7), 1883-1893. Article dkac133. https://doi.org/10.1093/jac/dkac133
https://dspace.library.uu.nl/bitstream/handle/1874/421443/dkac133.pdf?sequence=1
Simões, M., Janssen, N., Heederik, D. J. J., Smit, L. A. M., Vermeulen, R., & Huss, A. (2022). Residential proximity to livestock animals and mortality from respiratory diseases in The Netherlands: A prospective census-based cohort study. Environment international, 161, 1-8. Article 107140. https://doi.org/10.1016/j.envint.2022.107140
https://dspace.library.uu.nl/bitstream/handle/1874/419724/1_s2.0_S0160412022000666_main.pdf?sequence=1
Smit, L. A. M. (2022). The air we breathe: understanding the impact of the environment on pneumonia. Pneumonia, 14(1), 1-3. Article 2. https://doi.org/10.1186/s41479-022-00094-1
https://dspace.library.uu.nl/bitstream/handle/1874/419386/Smit2022_Article_TheAirWeBreatheUnderstandingTh.pdf?sequence=1
Yang, D., Heederik, D. J. J., Mevius, D. J., Scherpenisse, P., Luiken, R. E. C., Van Gompel, L., Skarżyńska, M., Wadepohl, K., Chauvin, C., Van Heijnsbergen, E., Wouters, I. M., Greve, G. D., Jongerius-Gortemaker, B. G. M., Tersteeg-Zijderveld, M., Zając, M., Wasyl, D., Juraschek, K., Fischer, J., Wagenaar, J. A., ... Schmitt, H. (2022). Risk factors for the abundance of antimicrobial resistance genes aph(3')-III, erm(B), sul2 and tet(W) in pig and broiler faeces in nine European countries. Journal of Antimicrobial Chemotherapy, 77(4), 969-978. Article dkac002. https://doi.org/10.1093/jac/dkac002
https://dspace.library.uu.nl/bitstream/handle/1874/419230/dkac002.pdf?sequence=1
Luiken, R. E., Heederik, D. J., Scherpenisse, P., Van Gompel, L., van Heijnsbergen, E., Greve, G. D., Jongerius-Gortemaker, B. G., Tersteeg-Zijderveld, M. H., Fischer, J., Juraschek, K., Skarżyńska, M., Zając, M., Wasyl, D., EFFORT Group, Wagenaar, J. A., Smit, L. A., Wouters, I. M., Mevius, D. J., & Schmitt, H. (2022). Determinants for antimicrobial resistance genes in farm dust on 333 poultry and pig farms in nine European countries. Environmental Research, 208, 1-9. Article 112715. https://doi.org/10.1016/j.envres.2022.112715
https://dspace.library.uu.nl/bitstream/handle/1874/419195/1_s2.0_S0013935122000421_main.pdf?sequence=1
van Aart, A. E., Velkers, F. C., Fischer, E. A. J., Broens, E. M., Egberink, H., Zhao, S., Engelsma, M., Hakze-van der Honing, R. W., Harders, F., de Rooij, M. M. T., Radstake, C., Meijer, P. A., Munnink, B. B. O., de Rond, J., Sikkema, R. S., van der Spek, A. N., Spierenburg, M., Wolters, W. J., Molenaar, R.-J., ... Smit, L. A. M. (2022). SARS-CoV-2 infection in cats and dogs in infected mink farms. Transboundary and emerging diseases, 69(5), 3001-3007. https://doi.org/10.1111/tbed.14173
https://dspace.library.uu.nl/bitstream/handle/1874/424396/Transbounding_Emerging_Dis_2021_Aart_SARS_CoV_2_infection_in_cats_and_dogs_in_infected_mink_farms.pdf?sequence=1

2021

Scholarly publications

Rooij, M. M. T. D., Sikkema, R. S., Bouwknegt, M., Geus, Y. D., Stanoeva, K. R., Nieuwenweg, S., Dam, A. S. G. V., Raben, C., Dohmen, W., Heederik, D., Reusken, C., Meijer, A., Koopmans, M. P. G., Franz, E., & Smit, L. A. M. (2021). Potential environmental transmission routes of SARS-CoV-2 inside a large meat processing plant experiencing COVID-19 clusters. (pp. 1-23). medRxiv. https://doi.org/10.1101/2021.06.20.21259212
https://dspace.library.uu.nl/bitstream/handle/1874/424260/2021.06.20.21259212v1.full.pdf?sequence=1
Lu, L., Sikkema, R. S., Velkers, F. C., Nieuwenhuijse, D. F., Fischer, E. A. J., Meijer, P. A., Bouwmeester-Vincken, N., Rietveld, A., Wegdam-Blans, M. C. A., Tolsma, P., Koppelman, M., Smit, L. A. M., Honing, R. W. H. D., Poel, W. H. M. V. D., Spek, A. N. V. D., Spierenburg, M. A. H., Molenaar, R. J., Rond, J. D., Augustijn-Schretlen, M., ... Koopmans, M. P. G. (2021). Adaptation, spread and transmission of SARS-CoV-2 in farmed minks and related humans in the Netherlands. (pp. 1-40). bioRxiv. https://doi.org/10.1101/2021.07.13.452160
https://dspace.library.uu.nl/bitstream/handle/1874/422634/2021.07.13.452160v1.full.pdf?sequence=1
Roof, I., van der Hoek, W., Oude Boerrigter, L., Wielders, C. C. H., & Smit, L. A. M. (2021). Use of Antibiotics among Residents Living Close to Poultry or Goat Farms: A Nationwide Analysis in The Netherlands. Antibiotics, 10(11), 1-12. Article 1346. https://doi.org/10.3390/antibiotics10111346
https://dspace.library.uu.nl/bitstream/handle/1874/413648/antibiotics_10_01346.pdf?sequence=1
Lu, L., Sikkema, R. S., Velkers, F. C., Nieuwenhuijse, D. F., Fischer, E. A. J., Meijer, P. A., Bouwmeester-Vincken, N., Rietveld, A., Wegdam-Blans, M. C. A., Tolsma, P., Koppelman, M., Smit, L. A. M., Hakze-van der Honing, R. W., van der Poel, W. H. M., van der Spek, A. N., Spierenburg, M. A. H., Molenaar, R. J., Rond, J. D., Augustijn, M., ... Koopmans, M. P. G. (2021). Adaptation, spread and transmission of SARS-CoV-2 in farmed minks and associated humans in the Netherlands. Nature Communications, 12(1), 1-12. Article 6802. https://doi.org/10.1038/s41467-021-27096-9
https://dspace.library.uu.nl/bitstream/handle/1874/413587/s41467_021_27096_9.pdf?sequence=1
Smit, L. A. M. (2021). Respiratory Diseases in Farmers. In S. Janes (Ed.), Encyclopedia of Respiratory Medicine, Second Edition (2 ed., Vol. 6, pp. 531-542). Academic Press. https://doi.org/10.1016/b978-0-12-801238-3.11500-4
Embregts, C. W. E., Verstrepen, B., Langermans, J. A. M., Böszörményi, K. P., Sikkema, R. S., de Vries, R. D., Hoffmann, D., Wernike, K., Smit, L. A. M., Zhao, S., Rockx, B., Koopmans, M. P. G., Haagmans, B. L., Kuiken, T., & GeurtsvanKessel, C. H. (2021). Evaluation of a multi-species SARS-CoV-2 surrogate virus neutralization test. One Health, 13, 1-8. Article 100313. https://doi.org/10.1016/j.onehlt.2021.100313
https://dspace.library.uu.nl/bitstream/handle/1874/412883/1_s2.0_S2352771421001038_main.pdf?sequence=1
de Rooij, M. M. T., Hakze-Van der Honing, R. W., Hulst, M. M., Harders, F., Engelsma, M., van de Hoef, W., Meliefste, K., Nieuwenweg, S., Oude Munnink, B. B., van Schothorst, I., Sikkema, R. S., van der Spek, A. N., Spierenburg, M., Spithoven, J., Bouwstra, R., Molenaar, R.-J., Koopmans, M., Stegeman, A., van der Poel, W. H. M., & Smit, L. A. M. (2021). Occupational and environmental exposure to SARS-CoV-2 in and around infected mink farms. Occupational and Environmental Medicine, 78(12), 893-899. https://doi.org/10.1136/oemed-2021-107443
https://dspace.library.uu.nl/bitstream/handle/1874/416169/893.full.pdf?sequence=1
Horie, M., Yang, D., Joosten, P., Munk, P., Wadepohl, K., Chauvin, C., Moyano, G., Skarżyńska, M., Dewulf, J., Aarestrup, F. M., Blaha, T., Sanders, P., Gonzalez-Zorn, B., Wasyl, D., Wagenaar, J. A., Heederik, D., Mevius, D., Schmitt, H., Smit, L. AM., & Gompel, L. V. (2021). Risk Factors for Antimicrobial Resistance in Turkey Farms: A Cross-Sectional Study in Three European Countries. Antibiotics, 10(7), 1-20. Article 820. https://doi.org/10.3390/antibiotics10070820
https://dspace.library.uu.nl/bitstream/handle/1874/412601/antibiotics_10_00820.pdf?sequence=1
Fakunle, A. G., Jafta, N., Naidoo, R. N., & Smit, L. A. M. (2021). Association of indoor microbial aerosols with respiratory symptoms among under-five children: a systematic review and meta-analysis. Environmental Health: A Global Access Science Source, 20(1), 1-16. Article 77. https://doi.org/10.1186/s12940-021-00759-2
https://dspace.library.uu.nl/bitstream/handle/1874/412528/s12940_021_00759_2.pdf?sequence=1
Zhao, S., Schuurman, N., Li, W., Wang, C., Smit, L. A. M., Broens, E. M., Wagenaar, J. A., van Kuppeveld, F. J. M., Bosch, B.-J., & Egberink, H. (2021). Serologic Screening of Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Cats and Dogs during First Coronavirus Disease Wave, the Netherlands. Emerging Infectious Diseases, 27(5), 1362-1370. https://doi.org/10.3201/eid2705.204055
https://dspace.library.uu.nl/bitstream/handle/1874/412008/20_4055.pdf?sequence=1
Kwok, K. T. T., de Rooij, M. M. T., Sinartio, F. F., Smit, L. A. M., Koopmans, M. P. G., & Phan, M. V. T. (2021). Genome Sequence of a Minacovirus Strain from a Farmed Mink in The Netherlands. Microbiology Resource Announcements, 10(8), Article e01451-20. https://doi.org/10.1128/MRA.01451-20
https://dspace.library.uu.nl/bitstream/handle/1874/411571/Microbiology_Resource_Announcements_2021_Kwok_e01451_20.full.pdf?sequence=1
Oude Munnink, B. B., Sikkema, R. S., Nieuwenhuijse, D. F., Molenaar, R. J., Munger, E., Molenkamp, R., van der Spek, A., Tolsma, P., Rietveld, A., Brouwer, M., Bouwmeester-Vincken, N., Harders, F., Hakze-van der Honing, R., Wegdam-Blans, M. C. A., Bouwstra, R. J., GeurtsvanKessel, C., van der Eijk, A. A., Velkers, F. C., Smit, L. A. M., ... Koopmans, M. P. G. (2021). Transmission of SARS-CoV-2 on mink farms between humans and mink and back to humans. Science (New York, N.Y.), 371(6525), 172-177. https://doi.org/10.1126/science.abe5901
https://dspace.library.uu.nl/bitstream/handle/1874/416129/science.abe5901.pdf?sequence=1
Post, P. M., Houthuijs, D., Sterk, H. A. M., Marra, M., van de Kassteele, J., van Pul, A., Smit, L. A. M., van der Hoek, W., Lebret, E., & Hogerwerf, L. (2021). Proximity to livestock farms and exposure to livestock-related particulate matter are associated with lower probability of medication dispensing for obstructive airway diseases. International Journal of Hygiene and Environmental Health, 231, Article 113651. https://doi.org/10.1016/j.ijheh.2020.113651
https://dspace.library.uu.nl/bitstream/handle/1874/409404/1_s2.0_S1438463920305976_main.pdf?sequence=1

2020

Scholarly publications

Gerbecks, J., Baliatsas, C., Yzermans, C. J., Smit, L. A. M., Huss, A., Heederik, D. J. J., & Dückers, M. L. A. (2020). Prevalence of non-specific health symptoms in livestock dense areas: Looking beyond respiratory conditions. International Journal of Hygiene and Environmental Health, 230, Article 113603. https://doi.org/10.1016/j.ijheh.2020.113603
https://dspace.library.uu.nl/bitstream/handle/1874/431912/1-s2.0-S1438463920305496-main.pdf?sequence=1
Luiken, R. E. C., Van Gompel, L., Bossers, A., Munk, P., Joosten, P., Hansen, R. B., Knudsen, B. E., García-Cobos, S., Dewulf, J., Aarestrup, F. M., Wagenaar, J. A., Smit, L. A. M., Mevius, D. J., Heederik, D. J. J., & Schmitt, H. (2020). Farm dust resistomes and bacterial microbiomes in European poultry and pig farms. Environment international, 143, Article 105971. https://doi.org/10.1016/j.envint.2020.105971
https://dspace.library.uu.nl/bitstream/handle/1874/408665/1_s2.0_S0160412020319267_main.pdf?sequence=1
Yang, D., Van Gompel, L., Luiken, R. E. C., Sanders, P., Joosten, P., van Heijnsbergen, E., Wouters, I. M., Scherpenisse, P., Chauvin, C., Wadepohl, K., Greve, G. D., Jongerius-Gortemaker, B. G. M., Tersteeg-Zijderveld, M., Soumet, C., Skarżyńska, M., Juraschek, K., Fischer, J., Wasyl, D., Wagenaar, J. A., ... Smit, L. A. M. (2020). Association of antimicrobial usage with faecal abundance of aph(3')-III, ermB, sul2 and tetW resistance genes in veal calves in three European countries. International Journal of Antimicrobial Agents, 56(4), Article 106131. https://doi.org/10.1016/j.ijantimicag.2020.106131
https://dspace.library.uu.nl/bitstream/handle/1874/408664/1_s2.0_S0924857920303149_main.pdf?sequence=1
Van Gompel, L., Luiken, R. E. C., Hansen, R. B., Munk, P., Bouwknegt, M., Heres, L., Greve, G. D., Scherpenisse, P., Jongerius-Gortemaker, B. G. M., Tersteeg-Zijderveld, M. H. G., García-Cobos, S., Dohmen, W., Dorado-García, A., Wagenaar, J. A., Urlings, B. A. P., Aarestrup, F. M., Mevius, D. J., Heederik, D. J. J., Schmitt, H., ... Smit, L. A. M. (2020). Description and determinants of the faecal resistome and microbiome of farmers and slaughterhouse workers: A metagenome-wide cross-sectional study. Environment international, 143, Article 105939. https://doi.org/10.1016/j.envint.2020.105939
https://dspace.library.uu.nl/bitstream/handle/1874/408585/1_s2.0_S0160412020318948_main.pdf?sequence=1
Molenaar, R. J., Vreman, S., Hakze-van der Honing, R. W., Zwart, R., de Rond, J., Weesendorp, E., Smit, L. A. M., Koopmans, M., Bouwstra, R., Stegeman, A., & van der Poel, W. H. M. (2020). Clinical and Pathological Findings in SARS-CoV-2 Disease Outbreaks in Farmed Mink (Neovison vison). Veterinary Pathology, 57(5), 653-657. https://doi.org/10.1177/0300985820943535
https://dspace.library.uu.nl/bitstream/handle/1874/408552/0300985820943535.pdf?sequence=1
Heederik, D. J. J., Smit, L. A. M., & Vermeulen, R. C. H. (2020). Go slow to go fast: A plea for sustained scientific rigour in air pollution research during the COVID-19 pandemic. European Respiratory Journal, 56(1), 1-4. Article 2001361. https://doi.org/10.1183/13993003.01361-2020
https://dspace.library.uu.nl/bitstream/handle/1874/408415/2001361.full.pdf?sequence=1
Oreshkova, N., Molenaar, R. J., Vreman, S., Harders, F., Oude Munnink, B. B., Van Der Honing, R. W. H., Gerhards, N., Tolsma, P., Bouwstra, R., Sikkema, R. S., Tacken, M. G. J., De Rooij, M. M. T., Weesendorp, E., Engelsma, M. Y., Bruschke, C. J. M., Smit, L. A. M., Koopmans, M., Van Der Poel, W. H. M., & Stegeman, A. (2020). SARS-CoV-2 infection in farmed minks, the Netherlands, April and May 2020. Eurosurveillance, 25(23), Article 2001005. https://doi.org/10.2807/1560-7917.ES.2020.25.23.2001005
https://dspace.library.uu.nl/bitstream/handle/1874/408412/eurosurv_25_23_1.pdf?sequence=1
Klous, G., Smit, L. A., van der Hoek, W., Kretzschmar, M. E., Vellema, P., Coutinho, R. A., Heederik, D. J., & Huss, A. (2020). Relationship between Coxiella burnetii (Q fever) antibody serology and time spent outdoors. The Journal of Infection, 81(1), 90-97. https://doi.org/10.1016/j.jinf.2020.04.013
https://dspace.library.uu.nl/bitstream/handle/1874/408147/1_s2.0_S0163445320302243_main.pdf?sequence=1
Fakunle, A. G., Olusola, B., Jafta, N., Faneye, A., Heederik, D., Smit, L. A. M., & Naidoo, R. N. (2020). Home Assessment of Indoor Microbiome (HAIM) in Relation to Lower Respiratory Tract Infections among Under-Five Children in Ibadan, Nigeria: The Study Protocol. International Journal of Environmental Research and Public Health, 17(6), Article 1857. https://doi.org/10.3390/ijerph17061857
https://dspace.library.uu.nl/bitstream/handle/1874/408056/ijerph_17_01857.pdf?sequence=1
Baliatsas, C., Dückers, M., Smit, L., Heederik, D., & Yzermans, J. (2020). Morbidity Rates in an Area with High Livestock Density: A Registry-Based Study Including Different Groups of Patients with Respiratory Health Problems. International Journal of Environmental Research and Public Health, 17(5), Article 1591. https://doi.org/10.3390/ijerph17051591
https://dspace.library.uu.nl/bitstream/handle/1874/408025/ijerph_17_01591_v3.pdf?sequence=1
Hordijk, J., Farmakioti, E., Smit, L. A., Duim, B., Graveland, H., Theelen, M. J. P., & Wagenaar, J. A. (2020). Fecal carriage of Extended Spectrum ß-Lactamase (ESBL)/AmpC-producing Escherichia coli in horses. Applied and Environmental Microbiology, 86(8), 1-9. Article e02590-19. https://doi.org/10.1128/AEM.02590-19
https://dspace.library.uu.nl/bitstream/handle/1874/407974/Applied_and_Environmental_Microbiology_2020_Hordijk_e02590_19.full.pdf?sequence=1
Van Gompel, L., Dohmen, W., Luiken, R. E. C., Bouwknegt, M., Heres, L., Van Heijnsbergen, E., Jongerius-Gortemaker, B. G. M., Scherpenisse, P., Greve, G. D., Tersteeg-Zijderveld, M. H. G., Wadepohl, K., Ribeiro Duarte, A. S., Muñoz-Gómez, V., Fischer, J., Skarżyńska, M., Wasyl, D., Wagenaar, J. A., Urlings, B. A. P., Dorado-García, A., ... Smit, L. A. M. (2020). Occupational Exposure and Carriage of Antimicrobial Resistance Genes (tetW, ermB) in Pig Slaughterhouse Workers. Annals of Work Exposures and Health, 64(2), 125-137. https://doi.org/10.1093/annweh/wxz098
https://dspace.library.uu.nl/bitstream/handle/1874/394091/wxz098.pdf?sequence=1

2019

Scholarly publications

van Kersen, W., Oldenwening, M., Aalders, B., Bloemsma, L. D., Borlée, F., Heederik, D., & Smit, L. A. M. (2019). Acute respiratory effects of livestock-related air pollution in a panel of COPD patients. Environment international, 136, Article 105426. https://doi.org/10.1016/j.envint.2019.105426
https://dspace.library.uu.nl/bitstream/handle/1874/389397/Acute_respiratory_effects.pdf?sequence=1
Post, P. M., Hogerwerf, L., Huss, A., Petie, R., Boender, G. J., Baliatsas, C., Lebret, E., Heederik, D., Hagenaars, T. J., IJzermans, C. J., & Smit, L. A. M. (2019). Risk of pneumonia among residents living near goat and poultry farms during 2014-2016. PLoS One, 14(10), Article 0223601. https://doi.org/10.1371/journal.pone.0223601
https://dspace.library.uu.nl/bitstream/handle/1874/386493/journal.pone.0223601.pdf?sequence=1
de Rooij, M. M. T., Smit, L. A. M., Erbrink, H. J., Hagenaars, T. J., Hoek, G., Ogink, N. W. M., Winkel, A., Heederik, D. J. J., & Wouters, I. M. (2019). Endotoxin and particulate matter emitted by livestock farms and respiratory health effects in neighboring residents. Environment international, 132, Article 105009. https://doi.org/10.1016/j.envint.2019.105009
https://dspace.library.uu.nl/bitstream/handle/1874/384918/Endotoxin_and_particulate_matter.pdf?sequence=1
Baliatsas, C., Smit, L. A. M., Dückers, M. L. A., van Dijk, C. E., Heederik, D., & Yzermans, C. J. (2019). Patients with overlapping diagnoses of asthma and COPD: is livestock exposure a risk factor for comorbidity and coexisting symptoms and infections? BMC Pulmonary Medicine, 19(1), Article 105. https://doi.org/10.1186/s12890-019-0865-z
https://dspace.library.uu.nl/bitstream/handle/1874/381544/Patients_with_overlapping_diagnoses.pdf?sequence=1
Luiken, R. E. C., Van Gompel, L., Munk, P., Sarrazin, S., Joosten, P., Dorado-García, A., Borup Hansen, R., Knudsen, B. E., Bossers, A., Wagenaar, J. A., Aarestrup, F. M., Dewulf, J., Mevius, D. J., Heederik, D. J. J., Smit, L. A. M., & Schmitt, H. (2019). Associations between antimicrobial use and the faecal resistome on broiler farms from nine European countries. Journal of Antimicrobial Chemotherapy, 74(9), 2596–2604. https://doi.org/10.1093/jac/dkz235
https://dspace.library.uu.nl/bitstream/handle/1874/407635/dkz235.pdf?sequence=1
Borlée, F., Yzermans, C. J., Oostwegel, F. S. M., Schellevis, F., Heederik, D., & Smit, L. A. (2019). Attitude toward livestock farming does not influence the earlier observed association between proximity to goat farms and self-reported pneumonia. Environmental Epidemiology, 3(2). https://doi.org/10.1097/EE9.0000000000000041
https://dspace.library.uu.nl/bitstream/handle/1874/380534/2019_Borlee_EnvEpidemiol.pdf?sequence=1
Van Gompel, L., Luiken, R. E. C., Sarrazin, S., Munk, P., Knudsen, B. E., Hansen, R. B., Bossers, A., Aarestrup, F. M., Dewulf, J., Wagenaar, J. A., Mevius, D. J., Schmitt, H., Heederik, D. J. J., Dorado-García, A., & Smit, L. A. M. (2019). The antimicrobial resistome in relation to antimicrobial use and biosecurity in pig farming, a metagenome-wide association study in nine European countries. Journal of Antimicrobial Chemotherapy, 74(4), 865-876. https://doi.org/10.1093/jac/dky518
https://dspace.library.uu.nl/bitstream/handle/1874/378894/dky518.pdf?sequence=1

2018

Scholarly publications

Munk, P., Knudsen, B. E., Lukjancenko, O., Duarte, A. S. R., Van Gompel, L., Luiken, R. E. C., Smit, L. A. M., Schmitt, H., Garcia, A. D., Hansen, R. B., Petersen, T. N., Bossers, A., Ruppé, E., Lund, O., Hald, T., Pamp, S. J., Vigre, H., Heederik, D., Wagenaar, J. A., ... Stärk, K. D. C. (2018). Erratum to: Abundance and diversity of the faecal resistome in slaughter pigs and broilers in nine European countries (Nature Microbiology, (2018), 3, 8, (898-908), 10.1038/s41564-018-0192-9). Nature Microbiology, 3(10), 1186. https://doi.org/10.1038/s41564-018-0241-4
https://dspace.library.uu.nl/bitstream/handle/1874/408488/s41564_018_0241_4.pdf?sequence=1
Munk, P., Knudsen, B. E., Lukjacenko, O., Duarte, A. S. R., Van Gompel, L., Luiken, R. E. C., Smit, L. A. M., Schmitt, H., Garcia, A. D., Hansen, R. B., Petersen, T. N., Bossers, A., Ruppé, E., Graveland, H., van Essen, A., Gonzalez-Zorn, B., Moyano, G., Sanders, P., Chauvin, C., ... Aarestrup, F. M. (2018). Abundance and diversity of the faecal resistome in slaughter pigs and broilers in nine European countries. Nature Microbiology, 3(8), 898-908. https://doi.org/10.1038/s41564-018-0192-9
https://dspace.library.uu.nl/bitstream/handle/1874/374667/munk.pdf?sequence=1
Kalkowska, D. A., Boender, G. J., Smit, L. A. M., Baliatsas, C., Yzermans, J., Heederik, D. J. J., & Hagenaars, T. J. (2018). Associations between pneumonia and residential distance to livestock farms over a five-year period in a large population-based study. PLoS One, 13(7), Article e0200813. https://doi.org/10.1371/journal.pone.0200813
https://dspace.library.uu.nl/bitstream/handle/1874/376511/journal.pone.0200813.pdf?sequence=1
Spierenburg, E. A. J., Portengen, L., Smit, L. A. M., Krop, E. J. M., Hylkema, M. N., Rijkers, G. T., Heederik, D., & Wouters, I. M. (2018). Stability of individual LPS-induced ex vivo cytokine release in a whole blood assay over a five-year interval. Journal of Immunological Methods, 460, 119-124. https://doi.org/10.1016/j.jim.2018.06.018
https://dspace.library.uu.nl/bitstream/handle/1874/376509/1_s2.0_S0022175918301960_main.pdf?sequence=1
Borlée, F., Yzermans, C. J., Krop, E. J. M., Maassen, C. B. M., Schellevis, F. G., Heederik, D. J. J., & Smit, L. A. M. (2018). Residential proximity to livestock farms is associated with a lower prevalence of atopy. Occupational and Environmental Medicine, 75(6), 453-460. https://doi.org/10.1136/oemed-2017-104769
https://dspace.library.uu.nl/bitstream/handle/1874/375891/residential.pdf?sequence=1
van der Star, B. J., van Dijk, C. E., Zock, J.-P., Smit, L. A. M., Baliatsas, C., Heederik, D. J. J., & Yzermans, C. J. (2018). Healthcare utilisation prior to the diagnosis of inflammatory bowel diseases and the influence of livestock exposure: A longitudinal case-control study. PLoS One, 13(4), Article e0195305. https://doi.org/10.1371/journal.pone.0195305
https://dspace.library.uu.nl/bitstream/handle/1874/375283/journal.pone.0195305.pdf?sequence=1
Klous, G., Smit, L. A. M., Freidl, G. S., Borlée, F., van der Hoek, W., IJzermans, C. J., Kretzschmar, M. E. E., Heederik, D. J. J., Coutinho, R. A., & Huss, A. (2018). Pneumonia risk of people living close to goat and poultry farms - Taking GPS derived mobility patterns into account. Environmental International, 115, 150-160. https://doi.org/10.1016/j.envint.2018.03.020
https://dspace.library.uu.nl/bitstream/handle/1874/375277/1_s2.0_S0160412017317907_main.pdf?sequence=1
Farokhi, A., Heederik, D., & Smit, L. A. M. (2018). Respiratory health effects of exposure to low levels of airborne endotoxin - a systematic review. Environmental Health: A Global Access Science Source, 17(1), Article 14. https://doi.org/10.1186/s12940-018-0360-7
https://dspace.library.uu.nl/bitstream/handle/1874/374957/farokhi.pdf?sequence=1
Strassle, P. D., Smit, L. A. M., & Hoppin, J. A. (2018). Endotoxin enhances respiratory effects of phthalates in adults: Results from NHANES 2005-6. Environmental Research, 162, 280-286. https://doi.org/10.1016/j.envres.2018.01.017
https://dspace.library.uu.nl/bitstream/handle/1874/374953/strassle.pdf?sequence=1
van Duijkeren, E., Wielders, C. C. H., Dierikx, C. M., van Hoek, A. H. A. M., Hengeveld, P., Veenman, C., Florijn, A., Lotterman, A., Smit, L. A. M., van Dissel, J. T., Maassen, C. B. M., & de Greeff, S. C. (2018). Long-term carriage of extended-spectrum β-lactamase-producing Escherichia coli and Klebsiella pneumoniae in the general population in the Netherlands. Clinical Infectious Diseases, 66(9), 1368-1376. https://doi.org/10.1093/cid/cix1015
https://dspace.library.uu.nl/bitstream/handle/1874/375244/cix1015.pdf?sequence=1
Downward, G. S., van der Zwaag, H. P., Simons, L., Meliefste, K., Tefera, Y., Carreon, J. R., Vermeulen, R., & Smit, L. A. M. (2018). Occupational exposure to indoor air pollution among bakery workers in Ethiopia; A comparison of electric and biomass cookstoves. Environmental Pollution, 233, 690-697. https://doi.org/10.1016/j.envpol.2017.10.094
https://dspace.library.uu.nl/bitstream/handle/1874/362134/downward.pdf?sequence=1

2017

Scholarly publications

Munk, P., Knudsen, B. E., Lukjacenko, O., Duarte, A. S. R., Luiken, R. E. C., Gompel, L. V., Smit, L. A. M., Schmitt, H., Garcia, A. D., Hansen, R. B., Petersen, T. N., Bossers, A., Ruppé, E., Lund, O., Tine, H., Pamp, S. J., Vigre, H., Heederik, D., Wagenaar, J. A., ... Aarestrup, F. M. (2017, Sept 28). Abundance and diversity of the fecal resistome in slaughter pigs and broilers in nine European countries. bioRxiv. https://doi.org/10.1101/194647
Spierenburg, E. A. J., Smit, L. A. M., Krop, E. J. M., Heederik, D., Hylkema, M. N., & Wouters, I. M. (2017). Occupational endotoxin exposure in association with atopic sensitization and respiratory health in adults: Results of a 5-year follow-up. PLoS One, 12(12), Article e0189097. https://doi.org/10.1371/journal.pone.0189097
https://dspace.library.uu.nl/bitstream/handle/1874/360482/endotoxin.pdf?sequence=1
Kramer, T., Jansen, L. E., Lipman, L. J. A., Smit, L. A. M., Heederik, D. J. J., & Dorado-García, A. (2017). Farmers' knowledge and expectations of antimicrobial use and resistance are strongly related to usage in Dutch livestock sectors. Preventive Veterinary Medicine, 147, 142-148. https://doi.org/10.1016/j.prevetmed.2017.08.023
https://dspace.library.uu.nl/bitstream/handle/1874/359806/1_s2.0_S0167587717304804_main.pdf?sequence=1
Pijnacker, R., Reimerink, J. H. J., Smit, L. A. M., van Gageldonk-Lafeber, A. B., Zock, J.-P., Borlée, F., Yzermans, C. J., Heederik, D. J. J., Maassen, C. B. M., & van der Hoek, W. (2017). Remarkable spatial variation in the seroprevalence of Coxiella burnetii after a large Q fever epidemic. BMC Infectious Diseases, 17(1), Article 725. https://doi.org/10.1186/s12879-017-2813-y
https://dspace.library.uu.nl/bitstream/handle/1874/359773/s12879_017_2813_y.pdf?sequence=1
Smit, L. A., & Heederik, D. J. J. (2017). Impacts of intensive livestock production on human health in densely populated regions. GeoHealth, 1(7), 272-277. https://doi.org/10.1002/2017GH000103
https://dspace.library.uu.nl/bitstream/handle/1874/360877/2017_Smit_GeoHealth.pdf?sequence=1
Timmerman, J. G., Heederik, D., Spee, T., van Rooy, F. G., Krop, E. J. M., Rustemeyer, T., & Smit, L. A. M. (2017). Contact dermatitis is an unrecognized problem in the construction industry: Comparison of four different assessment methods. American Journal of Industrial Medicine, 60(10), 879-888. https://doi.org/10.1002/ajim.22742
https://dspace.library.uu.nl/bitstream/handle/1874/360426/Timmerman_et_al_2017_American_Journal_of_Industrial_Medicine.pdf?sequence=1
Zomer, T. P., van Duijkeren, E., Wielders, C. C. H., Veenman, C., Hengeveld, P., {van der Hoek}, W., de Greeff, S. C., Smit, L. A. M., Heederik, D. J., Yzermans, C. J., Kuijper, E. J., & Maassen, C. B. M. (2017). Prevalence and risk factors for colonization of Clostridium difficile among adults living near livestock farms in the Netherlands. Epidemiology and Infection, 145(13), 2745-2749. https://doi.org/10.1017/S0950268817001753
https://dspace.library.uu.nl/bitstream/handle/1874/360863/prevalence_and_risk_factors_for_colonization_of_clostridium_difficile_among_adults_living_near_livestock_farms_in_the_netherlands.pdf?sequence=1
Klous, G., Smit, L. A. M., Borlée, F., Coutinho, R. A., Kretzschmar, M. E. E., Heederik, D. J. J., & Huss, A. (2017). Mobility assessment of a rural population in the Netherlands using GPS measurements. International Journal of Health Geographics, 16(1), Article 30. https://doi.org/10.1186/s12942-017-0103-y
https://dspace.library.uu.nl/bitstream/handle/1874/359760/s12942_017_0103_y.pdf?sequence=1
Borlée, F., Yzermans, C. J., Aalders, B., Rooijackers, J., Krop, E., Maassen, C. B. M., Schellevis, F., Brunekreef, B., Heederik, D., & Smit, L. A. M. (2017). Air Pollution from Livestock Farms is Associated with Airway Obstruction in Neighboring Residents. American Journal of Respiratory and Critical Care Medicine, 196(9), 1152-1161. https://doi.org/10.1164/rccm.201701-0021OC
https://dspace.library.uu.nl/bitstream/handle/1874/359745/rccm.201701_0021oc.pdf?sequence=1
Freidl, G. S., Spruijt, I. T., Borlée, F., Smit, L. A. M., van Gageldonk-Lafeber, A. B., Heederik, D. J. J., Yzermans, J., van Dijk, C. E., Maassen, C. B. M., & van der Hoek, W. (2017). Livestock-associated risk factors for pneumonia in an area of intensive animal farming in the Netherlands. PLoS One, 12(3), Article e0174796. https://doi.org/10.1371/journal.pone.0174796
https://dspace.library.uu.nl/bitstream/handle/1874/359726/journal.pone.0174796.pdf?sequence=1
Baliatsas, C., Borlée, F., van Dijk, C. E., van der Star, B., Zock, J.-P., Smit, L. A. M., Spreeuwenberg, P., Heederik, D., & Yzermans, C. J. (2017). Comorbidity and coexisting symptoms and infections presented in general practice by COPD patients: Does livestock density in the residential environment play a role? International Journal of Hygiene and Environmental Health, 220(4), 704-710. https://doi.org/10.1016/j.ijheh.2017.02.005
https://dspace.library.uu.nl/bitstream/handle/1874/359720/1_s2.0_S1438463916304722_main.pdf?sequence=1
Borlée, F., Yzermans, C. J., Krop, E., Aalders, B., Rooijackers, J., Zock, J.-P., van Dijk, C. E., Maassen, C. B. M., Schellevis, F., Heederik, D., & Smit, L. A. M. (2017). Spirometry, questionnaire and electronic medical record based COPD in a population survey: Comparing prevalence, level of agreement and associations with potential risk factors. PLoS One, 12(3), Article e0171494. https://doi.org/10.1371/journal.pone.0171494
https://dspace.library.uu.nl/bitstream/handle/1874/359719/journal.pone.0171494.pdf?sequence=1
Smit, L. A., Boender, G. J., de Steenhuijsen Piters, W. A. A., Hagenaars, T. J., Huijskens, E. G. W., Rossen, J. W. A., Koopmans, M., Nodelijk, G., Sanders, E. A. M., Yzermans, J., Bogaert, D., & Heederik, D. (2017). Increased risk of pneumonia in residents living near poultry farms: does the upper respiratory tract microbiota play a role? Pneumonia, 9, 1-9. Article 3. https://doi.org/10.1186/s41479-017-0027-0
https://dspace.library.uu.nl/bitstream/handle/1874/360800/2017_Smit_Pneumonia.pdf?sequence=1
van Gageldonk-Lafeber, A. B., van der Hoek, W., Borlée, F., Heederik, D. J. J., Mooi, S. H., Maassen, C. B. M., Yzermans, C. J., Rockx, B., Smit, L. A. M., & Reimerink, J. H. J. (2017). Hepatitis E virus seroprevalence among the general population in a livestock-dense area in the Netherlands: a cross-sectional population-based serological survey. BMC Infectious Diseases, 17(1). https://doi.org/10.1186/s12879-016-2160-4
https://dspace.library.uu.nl/bitstream/handle/1874/360382/s12879_016_2160_4.pdf?sequence=1
van Dijk, C. E., Zock, J.-P., Baliatsas, C., Smit, L. A. M., Borlée, F., Spreeuwenberg, P., Heederik, D., & Yzermans, C. J. (2017). Health conditions in rural areas with high livestock density: Analysis of seven consecutive years. Environmental Pollution, 222, 374-382. https://doi.org/10.1016/j.envpol.2016.12.023
https://dspace.library.uu.nl/bitstream/handle/1874/345572/1_s2.0_S0269749116310211_main.pdf?sequence=1
Zomer, T. P., Wielders, C. C. H., Veenman, C., Hengeveld, P., van der Hoek, W., de Greeff, S. C., Smit, L. A. M., Heederik, D. J., Yzermans, C. J., Bosch, T., Maassen, C. B. M., & van Duijkeren, E. (2017). MRSA in persons not living or working on a farm in a livestock-dense area: prevalence and risk factors. Journal of Antimicrobial Chemotherapy, 72(3), 893-899. https://doi.org/10.1093/jac/dkw483
https://dspace.library.uu.nl/bitstream/handle/1874/359694/mrsa.pdf?sequence=1
Wielders, C. C. H., van Hoek, A. H. A. M., Hengeveld, P. D., Veenman, C., Dierikx, C. M., Zomer, T. P., Smit, L. A. M., van der Hoek, W., Heederik, D. J., de Greeff, S. C., Maassen, C. B. M., & van Duijkeren, E. (2017). Extended-spectrum β-lactamase- and pAmpC-producing Enterobacteriaceae among the general population in a livestock-dense area. Clinical Microbiology and Infection, 23(2), 120.e1–120.e8. Article 120. https://doi.org/10.1016/j.cmi.2016.10.013
https://dspace.library.uu.nl/bitstream/handle/1874/346793/1_s2.0_S1198743X16304839_main.pdf?sequence=3

2016

Scholarly publications

Basinas, I., Wouters, I. M., Sigsgaard, T., Heederik, D., Spaan, S., Smit, L. A. M., Bønløkke, J. H., Eduard, W., Radon, K., Straumfors, A., Omland, Ø., Duchaine, C., Nowak, D., Schlünssen, V., & Kromhout, H. (2016). Development of a quantitative job exposure matrix for endotoxin exposure in agriculture. Occupational and Environmental Medicine, 73, 87. https://doi.org/10.1136/oemed-2016-103951.235
https://dspace.library.uu.nl/bitstream/handle/1874/407620/A88.1.full.pdf?sequence=1
Bloemsma, L. D., Hoek, G., & Smit, L. A. M. (2016). Panel studies of air pollution in patients with COPD: Systematic review and meta-analysis. Environmental Research, 151, 458-468. https://doi.org/10.1016/j.envres.2016.08.018
https://dspace.library.uu.nl/bitstream/handle/1874/345482/Panel.pdf?sequence=1
de Rooij, M. M. T., Borlée, F., Smit, L. A. M., de Bruin, A., Janse, I., Heederik, D. J. J., & Wouters, I. M. (2016). Detection of Coxiella burnetii in Ambient Air after a Large Q Fever Outbreak. PLoS One, 11(3), Article e0151281. https://doi.org/10.1371/journal.pone.0151281
https://dspace.library.uu.nl/bitstream/handle/1874/344407/Detection.PDF?sequence=1
Hooiveld, M., Smit, L. A. M., van der Sman-de Beer, F., Wouters, I. M., van Dijk, C. E., Spreeuwenberg, P., Heederik, D. J. J., & Yzermans, C. J. (2016). Doctor-diagnosed health problems in a region with a high density of concentrated animal feeding operations: a cross-sectional study. Environmental health, 15(1), 1-9. https://doi.org/10.1186/s12940-016-0123-2
https://dspace.library.uu.nl/bitstream/handle/1874/345431/2016_Hooiveld_EnvHealth.pdf?sequence=1
van Dijk, C. E., Smit, L. A. M., Hooiveld, M., Zock, J.-P., Wouters, I. M., Heederik, D. J. J., & Yzermans, C. J. (2016). Associations between proximity to livestock farms, primary health care visits and self-reported symptoms. BMC Family Practice [E], 17(1), Article 22. https://doi.org/10.1186/s12875-016-0421-3
https://dspace.library.uu.nl/bitstream/handle/1874/345007/2016_van_Dijk_BMCFamilyPractice.pdf?sequence=1
van Dijk, C. E., Garcia-Aymerich, J., Carsin, A.-E., Smit, L. A. M., Borlée, F., Heederik, D. J., Donker, G. A., Yzermans, C. J., & Zock, J.-P. (2016). Risk of exacerbations in COPD and asthma patients living in the neighbourhood of livestock farms: Observational study using longitudinal data. International Journal of Hygiene and Environmental Health, 219(3), 278–287. https://doi.org/10.1016/j.ijheh.2016.01.002
https://dspace.library.uu.nl/bitstream/handle/1874/394561/Risk_of_exacerbations_in_COPD.pdf?sequence=1
Spee, T., Timmerman, J. G., Rühl, R., Kersting, K., Heederik, D. J. J., & Smit, L. A. M. (2016). Determinants of epoxy allergy in the construction industry: a case-control study. Contact Dermatitis, 74(5), 259-266. https://doi.org/10.1111/cod.12529
https://dspace.library.uu.nl/bitstream/handle/1874/344400/Determinants.pdf?sequence=1
Boers, D., Geelen, L., Erbrink, H., Smit, L. A. M., Heederik, D., Hooiveld, M., Yzermans, C. J., Huijbregts, M., & Wouters, I. M. (2016). The relation between modeled odor exposure from livestock farming and odor annoyance among neighboring residents. International Archives of Occupational and Environmental Health, 89(3), 521-530. https://doi.org/10.1007/s00420-015-1092-4
https://dspace.library.uu.nl/bitstream/handle/1874/330829/4.pdf?sequence=1
Timmerman, J. G., Heederik, D., Spee, T., van Rooy, F. G., Krop, E. J. M., Koppelman, G. H., Rustemeyer, T., & Smit, L. A. M. (2016). Contact dermatitis in the construction industry: the role of filaggrin loss-of-function mutations. British Journal of Dermatology, 174(2), 348-355. https://doi.org/10.1111/bjd.14215
Huijskens, E. G. W., Smit, L. A. M., Rossen, J. W. A., Heederik, D., & Koopmans, M. (2016). Evaluation of Patients with Community-Acquired Pneumonia Caused by Zoonotic Pathogens in an Area with a High Density of Animal Farms. Zoonoses and Public Health, 63(2), 160-166. https://doi.org/10.1111/zph.12218
https://dspace.library.uu.nl/bitstream/handle/1874/330597/Huijskens.pdf?sequence=1

Other output

Spierenburg, A., Smit, L., Robbe, P., Krop, E., Heederik, D., Hylkema, M., & Wouters, I. (2016). Occupational endotoxin exposure dose-dependently protects against atopy and hay fever: Results of a longitudinal study. Abstract from ERS International Congress 2016 , London, United Kingdom. https://doi.org/10.1183/13993003.congress-2016.PA391

2015

Scholarly publications

Borlée, F., Yzermans, C. J., van Dijk, C. E., Heederik, D., & Smit, L. A. M. (2015). Increased respiratory symptoms in COPD patients living in the vicinity of livestock farms. European Respiratory Journal, 46(6), 1605-1614. https://doi.org/10.1183/13993003.00265-2015
https://dspace.library.uu.nl/bitstream/handle/1874/329372/COPD.pdf?sequence=1
Heederik, D., & Smit, L. A. M. (2015). Gender differences in lung function recovery after cessation of occupational endotoxin exposure: a complex story. Occupational and Environmental Medicine, 72(8), 543-4. https://doi.org/10.1136/oemed-2014-102783
https://dspace.library.uu.nl/bitstream/handle/1874/329336/Gender.pdf?sequence=1
Spierenburg, E. A. J., Smit, L. A. M., Heederik, D., Robbe, P., Hylkema, M. N., & Wouters, I. M. (2015). Healthy worker survivor analysis in an occupational cohort study of Dutch agricultural workers. International Archives of Occupational and Environmental Health, 88(8), 1165-1173. https://doi.org/10.1007/s00420-015-1047-9
https://dspace.library.uu.nl/bitstream/handle/1874/329335/art_3A10.pdf?sequence=1
Bouzigon, E., Nadif, R., Le Moual, N., Dizier, M.-H., Aschard, H., Boudier, A., Bousquet, J., Chanoine, S., Donnay, C., Dumas, O., Gormand, F., Jacquemin, B., Just, J., Margaritte-Jeannin, P., Matran, R., Pison, C., Rage, E., Rava, M., Sarnowski, C., ... Siroux, V. (2015). Facteurs génétiques et environnementaux de l'asthme et de l'allergie: synthèse des résultats de l'étude EGEA. Revue des Maladies Respiratoires, 32(8), 822-840. https://doi.org/10.1016/j.rmr.2014.12.005
Hooiveld, M., van Dijk, C., van der Sman-de Beer, F., Smit, L. A. M., Vogelaar, M., Wouters, I. M., Heederik, D. J., & Yzermans, C. J. (2015). Odour annoyance in the neighbourhood of livestock farming - perceived health and health care seeking behaviour. Annals of Agricultural and Environmental Medicine, 22(1), 55-61. https://doi.org/10.5604/12321966.1141369
https://dspace.library.uu.nl/bitstream/handle/1874/327547/Odour.pdf?sequence=1
Smit, L. A. M., Lenters, V., Høyer, B. B., Lindh, C. H., Pedersen, H. S., Liermontova, I., Jönsson, B. A. G., Piersma, A. H., Bonde, J. P., Toft, G., Vermeulen, R., & Heederik, D. (2015). Prenatal exposure to environmental chemical contaminants and asthma and eczema in school-age children. Allergy, 70(6), 653-660. https://doi.org/10.1111/all.12605
https://dspace.library.uu.nl/bitstream/handle/1874/329306/Smit.pdf?sequence=1
Lenters, V., Portengen, L., Smit, L. A. M., Jönsson, B. A. G., Giwercman, A., Rylander, L., Lindh, C. H., Spanò, M., Pedersen, H. S., Ludwicki, J. K., Chumak, L., Piersma, A. H., Toft, G., Bonde, J. P., Heederik, D., & Vermeulen, R. (2015). Phthalates, perfluoroalkyl acids, metals and organochlorines and reproductive function: a multipollutant assessment in Greenlandic, Polish and Ukrainian men. Occupational and Environmental Medicine, 72(6), 385-393. https://doi.org/10.1136/oemed-2014-102264
https://dspace.library.uu.nl/bitstream/handle/1874/307775/Lenters_OEM_2014_sPLSR_contaminants_male_repro_CLEAR_.pdf?sequence=2
Rava, M., Smit, L. A. M., & Nadif, R. (2015). Gene-environment interactions in the study of asthma in the postgenomewide association studies era. Current Opinion in Allergy and Clinical Immunology, 15(1), 70-78. https://doi.org/10.1097/ACI.0000000000000131
https://dspace.library.uu.nl/bitstream/handle/1874/329273/00130832.pdf?sequence=1

2014

Scholarly publications

Smit, L. A. M., & Heederik, D. (2014). Are neighboring residents at risk of health effects from animal farm emissions? Tijdschrift voor Diergeneeskunde, 138(10), 22-26.
Smit, L. A. M., Hooiveld, M., van der Sman-de Beer, F., Opstal-van Winden, A. W. J., Beekhuizen, J., Wouters, I. M., Yzermans, C. J., & Heederik, D. (2014). Air pollution from livestock farms, and asthma, allergic rhinitis and COPD among neighbouring residents. Occupational and Environmental Medicine, 71(2), 134-140. https://doi.org/10.1136/oemed-2013-101485
https://dspace.library.uu.nl/bitstream/handle/1874/305125/134.full.pdf?sequence=1
Timmerman, J. G., Heederik, D., Spee, T., & Smit, L. A. M. (2014). Skin symptoms in the construction industry: occurrence and determinants. American Journal of Industrial Medicine, 57(6), 660-668. https://doi.org/10.1002/ajim.22314
https://dspace.library.uu.nl/bitstream/handle/1874/305097/14.pdf?sequence=1
Smit, L. A. M., Strachan, D. P., Vermeulen, R., de Bakker, P. I. W., Demenais, F., Dumas, O., Carsin, A.-E., Cullinan, P., Curjuric, I., Ghosh, R. E., Heederik, D., Imboden, M., Jarvis, D., Lathrop, M., Le Moual, N., Mehta, A., Miedinger, D., Sigsgaard, T., Siroux, V., ... Bouzigon, E. (2014). Human leukocyte antigen class II variants and adult-onset asthma: does occupational allergen exposure play a role? European Respiratory Journal, 44(5), 1234-1242. https://doi.org/10.1183/09031936.00068014
https://dspace.library.uu.nl/bitstream/handle/1874/305075/1234.full.pdf?sequence=1
Timmerman, J. G., Zilaout, H., Heederik, D., Spee, T., & Smit, L. A. M. (2014). Validation of a questionnaire on hand hygiene in the construction industry. Annals of Occupational Hygiene, 58(8), 1046-1056. https://doi.org/10.1093/annhyg/meu053
https://dspace.library.uu.nl/bitstream/handle/1874/304936/Ann_Occup_Hyg_2014_Timmerman_1046_56.pdf?sequence=1

2013

Scholarly publications

Lenters, V. C., Thomsen, C., Smit, L. A., Jönsson, B. A. G., Pedersen, H. S., Ludwicki, J. K., Zviezdai, V., Piersma, A. H., Toft, G., Bonde, J. P., Becher, G., Vermeulen, R., & Heederik, D. (2013). Serum concentrations of polybrominated diphenyl ethers (PBDEs) and a polybrominated biphenyl (PBB) in men from Greenland, Poland and Ukraine. Environment international, 61, 8-16. https://doi.org/10.1016/j.envint.2013.09.001
https://dspace.library.uu.nl/bitstream/handle/1874/304044/1.pdf?sequence=4

2012

Scholarly publications

Smit, L. A., van der Sman-de Beer, F., Opstal-van Winden, A. W. J., Hooiveld, M., Beekhuizen, J., Wouters, I. M., Yzermans, J., & Heederik, D. J. J. (2012). Q Fever and pneumonia in an area with a high livestock density: a large population-based study. PLoS One, 7(6), Article e38843. https://doi.org/10.1371/journal.pone.0038843
https://dspace.library.uu.nl/bitstream/handle/1874/259893/Smit-Plos-ONE_2012_7_e38843.pdf?sequence=1
Smit, L. A., Kogevinas, M., Antó, J., Bouzigon, E., González, J. R., Le Moual, N., Kromhout, J., Carsin, A., Pin, I., Jarvis, D., Vermeulen, R. C. H., Janson, C., Heinrich, J., Gut, I., Lathrop, M., Valverde, M. A., Demenais, F., & Kauffmann, F. (2012). Transient receptor potential genes, smoking, occupational exposures and cough in adults. Respiratory Research, 13(1), 26. https://doi.org/10.1186/1465-9921-13-26
https://dspace.library.uu.nl/bitstream/handle/1874/259894/Smit-Respir_Res_2012_13_26pages.pdf?sequence=1
Noss, I., Wouters, I. M., Smit, L. A., Meijer, E., Pronk, A., Heederik, D. J. J., & Doekes, G. (2012). IgG to Various Beta-Glucans in a Human Adult Population. International Archives of Allergy and Immunology, 157(1), 98-108. https://doi.org/10.1159/000324674
https://dspace.library.uu.nl/bitstream/handle/1874/273396/Noss-Int_Arch_Allergy_Immunol_2012_157_98-108.pdf?sequence=1
Smit, L. A. (2012). Respiratory health effects in agricultural workers: are some more susceptible than others? Expert Review of Respiratory Medicine, 6(1), 7-10. https://doi.org/10.1586/ers.11.86
Basinas, I., Schlünssen, V., Heederik, D., Sigsgaard, T., Smit, L. A., Samadi, S., Omland, O., Hjort, C., Madsen, A. M., Skov, S., & Wouters, I. M. (2012). Sensitisation to common allergens and respiratory symptoms in endotoxin exposed workers: a pooled analysis. Occupational and Environmental Medicine, 69(2), 99-106. https://doi.org/10.1136/oem.2011.065169
https://dspace.library.uu.nl/bitstream/handle/1874/272804/99.full.pdf?sequence=2

Professional publications

Uijt de Haag, P. A. M., Bellamy, L. J., Burdorf, A., Ter burg, W., Eysink, P., Heederik, D. J. J., Klein Entink, R. H., Manuel, H. J., Papazoglou, I. A., Pronk, A., Smit, L. A., Tielemans, E., & Timmerman, J. (2012). Occupational health or occupational safety: which impact is larger? (RIVM report ed.) Rijksinstituut voor Volksgezondheid en Milieu.

2011

Scholarly publications

Smit, L. A., Heederik, D., Doekes, G., Koppelman, G. H., Bottema, R. W. B., Postma, D. S., & Wouters, I. M. (2011). Endotoxin exposure, CD14 and wheeze among farmers: a gene--environment interaction. Occupational and Environmental Medicine, 68(11), 826-831. https://doi.org/10.1136/oem.2010.060038
https://dspace.library.uu.nl/bitstream/handle/1874/407262/826.full.pdf?sequence=1
Smit, L. A., Bouzigon, E., Bousquet, J., le Moual, N., Nadif, R., Pin, I., Lathrop, M., Demenais, F., Kauffmann, F., & Siroux, V. (2011). Mold allergen sensitization in adult asthma according to integrin β3 polymorphisms and Toll-like receptor 2/+596 genotype. Journal of Allergy and Clinical Immunology, 128(1), 185-191.e7. https://doi.org/10.1016/j.jaci.2011.04.007
Dumas, O., Smit, L. A., Pin, I., Kromhout, H., Siroux, V., Nadif, R., Vermeulen, R., Heederik, D., Hery, M., Choudat, D., Kauffmann, F., & le Moual, N. (2011). Do young adults with childhood asthma avoid occupational exposures at first hire? European Respiratory Journal, 37(5), 1043-1049. https://doi.org/10.1183/09031936.00057610
https://dspace.library.uu.nl/bitstream/handle/1874/407037/1043.full.pdf?sequence=1

Professional publications

Heederik, D., IJzermans, C. J., Opstal - van Winden, A. W. J., Smit, L. A., Wouters, I. M., Hooiveld, M., van der Sman, F., Spreeuwenberg, P. P. M., de Bruin, A., & Rotterdam, B. (2011). Mogelijke effecten van intensieve veehouderij op de gezondheid van omwonenden. IRAS, Nivel, RIVM. http://www.rijksoverheid.nl/documenten-en-publicaties/rapporten/2011/06/21/mogelijke-effecten-intensieve-veehouderij-op-gezondheid-omwonenden.html

2010

Scholarly publications

Smit, L. A., Bouzigon, E., Pin, V., Siroux, V., Monier, F., Aschard, H., Bousquet, J., Gormand, F., Just, J., le Moual, N., Nadif, R., Scheinmann, P., Vervloet, D., Lathrop, M., Demenais, F., & Kauffmann, F. (2010). 17q21 variants modify the association between early respiratory infections and asthma. European Respiratory Journal, 36(1), 57-64. https://doi.org/10.1183/09031936.00154509
Cantero-Recasens, G., Gonzalez, J. R., Fandos, C., Duran-Tauleria, E., Smit, L. A., Kauffmann, F., Anto, J. M., & Valverde, M. A. (2010). Loss of function of transient receptor potential vanilloid 1 (TRPV1) genetic variant is associated with lower risk of active childhood asthma. Journal of Biological Chemistry, 285(36), 27532-27535. https://doi.org/10.1074/jbc.C110.159491
Smit, L. A., Heederik, D., Doekes, G., Lammers, J. W. J., & Wouters, I. M. (2010). Occupational endotoxin exposure reduces the risk of atopic sensitization but increases the risk of bronchial hyperresponsiveness. International Archives of Allergy and Immunology, 152(2), 151-158. https://doi.org/10.1159/000265536
https://dspace.library.uu.nl/bitstream/handle/1874/204564/Smit-Int_Arch_Allergy_Immunol_2010_152_151-158.pdf?sequence=1

2009

Scholarly publications

Smit, L. A., Heederik, D. J. J., Doekes, G., & Wouters, I. M. (2009). Exhaled nitric oxide in endotoxin-exposed adults: effect modification by smoking and atopy. Occupational and Environmental Medicine, 66(4), 251-255. https://doi.org/10.1136/oem.2008.042465
https://dspace.library.uu.nl/bitstream/handle/1874/39542/Smit-Occup_Environ_Med_2009_66_251-255.pdf?sequence=1
Smit, L. A., Heederik, D. J. J., Doekes, G., Krop, E. J. M., Rijkers, G. T., & Wouters, I. M. (2009). Ex vivo cytokine release reflects sensitivity to occupational endotoxin exposure. European Respiratory Journal, 34(4), 795-802. https://doi.org/10.1183/09031936.00161908
https://dspace.library.uu.nl/bitstream/handle/1874/39434/Smit-Eur_Respir_J_2009_34_795-802.pdf?sequence=1
van Rooy, F. G., Smit, L. A., Houba, R., Zaat, V. A., Rooijackers, J. M., & Heederik, D. J. J. (2009). A cross-sectional study of lung function and respiratory symptoms among chemical workers producing diacetyl for food flavourings. Occupational and Environmental Medicine, 66(2), 105-110. https://doi.org/10.1136/oem.2008.039560
https://dspace.library.uu.nl/bitstream/handle/1874/39446/Rooy-Occup_Environ_Med_2009_66_105-110.pdf?sequence=1
Smit, L. A., Siroux, V., Bouzigon, E., Oryszczyn, M. P., Lathrop, M., Demenais, F., & Kauffmann, F. (2009). CD14 and toll-like receptor gene polymorphisms, country living, and asthma in adults. American Journal of Respiratory and Critical Care Medicine, 179(5), 363-368.

Professional publications

Douwes, J., Smit, L. A., & Heederik, D. J. J. (2009). Beschermende effecten van het opgroeien en werken op een boerderij op de ontwikkeling van atopische ziekten. Nederlands Tijdschrift voor Allergie, 9(1), 3-15. https://www.ariez.nl/wp-content/uploads/2018/08/3-15.pdf
https://dspace.library.uu.nl/bitstream/handle/1874/407278/3_15.pdf?sequence=1
Smit, L. A., Wouters, I. M., Heederik, D., & Douwes, J. (2009). Gezondheidseffecten van blootstelling aan endotoxine. Een overzicht en de relevantie voor de veterinaire praktijk. Tijdschrift voor Diergeneeskunde, 134(20), 840-846.

2008

Scholarly publications

Smit, L. A., Heederik, D., Doekes, G., Blom, C., van Zweden, I., & Wouters, I. M. (2008). Exposure-response analysis of allergy and respiratory symptoms in endotoxin-exposed adults. European Respiratory Journal, 31(6), 1241-1248. https://doi.org/10.1183/09031936.00090607
https://dspace.library.uu.nl/bitstream/handle/1874/407163/1241.full.pdf?sequence=1
Spaan, S., Smit, L. A., Eduard, W., Larsson, L., Arts, H. J., Wouters, I. M., & Heederik, D. (2008). Endotoxin Exposure in Sewage Treatment Workers: Investigation of Exposure Variability and Comparison of Analytical Techniques. Annals of Agricultural and Environmental Medicine, 15(2), 251-261.
https://dspace.library.uu.nl/bitstream/handle/1874/407143/15251.pdf?sequence=1
Smit, L. A. (2008). Respiratory effects of endotoxin exposure : Individual susceptibility and gene-environment interactions. [Doctoral thesis 1 (Research UU / Graduation UU), Utrecht University]. Utrecht University.
https://dspace.library.uu.nl/bitstream/handle/1874/31142/smit.pdf?sequence=2

2007

Scholarly publications

Smit, L. A., Zuurbier, M., Doekes, G., Wouters, I. M., Heederik, D. J. J., & Douwes, J. (2007). Hay fever and asthma symptoms in conventional and organic farmers in the Netherlands. Occupational and Environmental Medicine, 64(2), 101-107. https://doi.org/10.1136/oem.2006.028167
https://dspace.library.uu.nl/bitstream/handle/1874/407189/101.full.pdf?sequence=1
van Rooy, F. G., Rooyackers, J. M., Prokop, W. M., Houba, R., Smit, L. A., & Heederik, D. J. J. (2007). Bronchiolitis obliterans syndrome in chemical workers producing diacetyl for food flavorings. American Journal of Respiratory and Critical Care Medicine, 176(5), 498-504. https://doi.org/10.1164/rccm.200611-1620OC
https://dspace.library.uu.nl/bitstream/handle/1874/407050/rccm.200611_1620oc.pdf?sequence=1
Smit, L. A., Bongers, S. I. M., Ruven, H. J., Rijkers, G. T., Wouters, I. M., Heederik, D. J. J., Omland, O., & Sigsgaard, T. (2007). Atopy and new-onset asthma in young Danish farmers in the Netherlands and CD14, TLR2, and TLR4 genetic polymorphisms: a nested case‐control study. Clinical and Experimental Allergy, 37(11), 1602-1608. https://doi.org/10.1111/j.1365-2222.2007.02831.x
https://dspace.library.uu.nl/bitstream/handle/1874/407047/Atopy.pdf?sequence=1

2006

Scholarly publications

Visser, M. J., Spaan, S., Arts, H. J., Smit, L. A., & Heederik, D. J. J. (2006). Influence of different cleaning practices on endotoxin exposure at sewage treatment plants. Annals of Occupational Hygiene, 50(7), 731-736. https://doi.org/10.1093/annhyg/mel026
https://dspace.library.uu.nl/bitstream/handle/1874/407276/mel026.pdf?sequence=1
Smit, L. A., Wouters, I. M., Hobo, M. M., Eduard, W., Doekes, G., & Heederik, D. J. J. (2006). Agricultural seed dust as a potential cause of organic dust toxic syndrome. Occupational and Environmental Medicine, 63(1), 59-67. https://doi.org/10.1136/oem.2005.021527
https://dspace.library.uu.nl/bitstream/handle/1874/407240/59.pdf?sequence=1

2005

Scholarly publications

Smit, L. A., Spaan, S., & Heederik, D. J. J. (2005). Endotoxin exposure and symptoms in wastewater treatment workers. American Journal of Industrial Medicine, 48(1), 30-39. https://doi.org/10.1002/ajim.20176
https://dspace.library.uu.nl/bitstream/handle/1874/395969/ajim.20176.pdf?sequence=1

2003

Scholarly publications

Smit, L. A. M., van-Wendel-de-Joode, B. N., Heederik, D., Peiris-John, R. J., & van der Hoek, W. (2003). Neurological symptoms among Sri Lankan farmers occupationally exposed to acetylcholinesterase-inhibiting insecticides. American Journal of Industrial Medicine, 44(3), 254-264. https://doi.org/10.1002/ajim.10271
https://dspace.library.uu.nl/bitstream/handle/1874/406997/ajim.10271.pdf?sequence=1

2002

Scholarly publications

Eddleston, M., Karalliedde, L., Buckley, N., Fernando, R., Hutchinson, G., Isbister, G., Konradsen, F., Murray, D., Piola, JC., Senanyake, N., Sheriff, R., Singh, S., Siwach, SB., & Smit, L. (2002). Pesticide poisoning in the developing world - a minimum pesticides list. The Lancet, 360(9340), 1163-1167.
Peiris-John, R. J., Ruberu, D. K., Wickremasinghe, A. R., Smit, L. A. M., & van der Hoek, W. (2002). Effects of occupational exposure to organophosphate pesticides on nerve and neuromuscular function. Journal of Occupational and Environmental Medicine, 44(4), 352-7.