dr. K. (Klaartje) Houben
Gegenereerd op 2018-04-26 15:12:26


Profile

As scientific supervisor of the uNMR-NL consortium, I am responsible for the 950MHz spectrometer that will be installed at Utrecht University in 2015. Peer-reviewed access to this spectrometer will be provided to research institutions as well as companies in the Netherlands. In addition I am facility manager of the Utrecht NMR facility that provides access to both Dutch and European scientists.

My research focusses on the study of the structure and dynamics of membrane proteins with NMR.

Gegenereerd op 2018-04-26 15:12:26
Curriculum vitae Download PDF
Gegenereerd op 2018-04-26 15:12:26
All publications
  2018 - Scholarly publications
Chowdhury, Abhishek Dutta, Houben, Klaartje, Whiting, Gareth T., Chung, Sangho, Baldus, Marc & Weckhuysen, Bert M. (01.01.2018). Electrophilic aromatic substitution over zeolites generates Wheland-type reaction intermediates. Nature Catalysis, 1 (1), (pp. 23-31).
Vollmer, Ina, Li, Guanna, Yarulina, Irina, Kosinov, Nikolay, Hensen, Emiel J M, Houben, Klaartje, Mance, Deni, Baldus, Marc, Gascon, Jorge & Kapteijn, Frederik (2018). Relevance of the Mo-precursor State in H-ZSM-5 for the Methane Dehydroaromatization. Catalysis Science and Technology (3).
  2017 - Scholarly publications
Atherton, Joseph, Jiang, Kai, Stangier, Marcel M, Luo, Yanzhang, Hua, Shasha, Houben, Klaartje, van Hooff, Jolien J E, Joseph, Agnel-Praveen, Scarabelli, Guido, Grant, Barry J, Roberts, Anthony J, Topf, Maya, Steinmetz, Michel O., Baldus, Marc, Moores, Carolyn A & Akhmanova, Anna (2017). A structural model for microtubule minus-end recognition and protection by CAMSAP proteins. Nature Structural and Molecular Biology, 24 (11), (pp. 931-943).
  2016 - Scholarly publications
Medeiros-Silva, João, Mance, Deni, Daniëls, Mark, Jekhmane, Miranda, Houben, Klaartje, Baldus, Marc & Weingarth, Markus (17.10.2016). 1H-Detected Solid-State NMR Studies of Water-Inaccessible Proteins In Vitro and In Situ. Angewandte Chemie-International Edition, 55 (43), (pp. 13606-13610) (5 p.).
Huculeci, Radu, Cilia, Elisa, Lyczek, Agatha, Buts, Lieven, Houben, Klaartje, Seeliger, Markus A, van Nuland, Nico & Lenaerts, Tom (28.09.2016). Dynamically Coupled Residues within the SH2 Domain of FYN Are Key to Unlocking Its Activity. Structure with Folding & design, 24 (11), (pp. 1947–1959) (13 p.). Copyright © 2016 Elsevier Ltd. All rights reserved..
Kaplan, M., Narasimhan, Siddarth, de Heus, Cilia, Mance, Deni, van Doorn, Sander, Houben, Klaartje, Popov-Celeketic, Dusan, Damman, Reinier, Katrukha, Eugene A, Jain, Purvi, Geerts, Willie J C, Heck, Albert J R, Folkers, Gert E, Kapitein, Lukas C, Lemeer, Simone, van Bergen En Henegouwen, Paul M P & Baldus, Marc (17.11.2016). EGFR Dynamics Change during Activation in Native Membranes as Revealed by NMR. Cell, 167 (5), (pp. 1241-1251.e11) (11 p.). Copyright © 2016 Elsevier Inc. All rights reserved..
Chowdhury, Abhishek Dutta, Houben, Klaartje, Whiting, Gareth T, Mokhtar, Mohamed, Asiri, Abdullah M, Al-Thabaiti, Shaeel A, Basahel, Suliman N, Baldus, Marc & Weckhuysen, Bert M (19.12.2016). Initial Carbon-Carbon Bond Formation during the Early Stages of the Methanol-to-Olefin Process Proven by Zeolite-Trapped Acetate and Methyl Acetate. Angewandte Chemie-International Edition, 55 (51), (pp. 15840-15845) (6 p.). © 2016 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA..
Kaplan, M., de Agrela Pinto, Cecilia, Houben, Klaartje & Baldus, Marc (2016). Nuclear magnetic resonance (NMR) applied to membrane-protein complexes. Quarterly Reviews of Biophysics, 49.
Chung, Sangho, Angelici, Carlo, Hinterding, Stijn O. M., Weingarth, Markus, Baldus, Marc, Houben, Klaartje, Weckhuysen, Bert M. & Bruijnincx, Pieter C. A. (2016). Role of Magnesium Silicates in Wet-Kneaded Silica-Magnesia Catalysts for the Lebedev Ethanol-to-Butadiene Process. ACS Catalysis, 6 (6), (pp. 4034-4045) (12 p.).
Yarulina, Irina, Bailleul, Simon, Pustovarenko, Alexey, Martinez, Javier Ruiz, Wispelaere, Kristof De, Hajek, Julianna, Weckhuysen, Bert M., Houben, Klaartje, Baldus, Marc, Van Speybroeck, Veronique, Kapteijn, Freek & Gascon, Jorge (06.10.2016). Suppression of the Aromatic Cycle in Methanol-to-Olefins Reaction over ZSM-5 by Post-Synthetic Modification Using Calcium. ChemCatChem, 8 (19), (pp. 3057-3063) (7 p.).
  2015 - Scholarly publications
Mance, Deni, Sinnige, Tessa, Kaplan, M., Narasimhan, Siddarth, Daniëls, Mark, Houben, Klaartje, Baldus, Marc & Weingarth, Markus (2015). An Efficient Labelling Approach to Harness Backbone and Side-Chain Protons in 1H-Detected Solid-State NMR Spectroscopy. Angewandte Chemie-International Edition, 54 (52), (pp. 15799-15803) (5 p.).
Sinnige, Tessa, Weingarth, Markus, Daniels, Mark, Boelens, Rolf, Bonvin, Alexandre M. J. J., Houben, Klaartje & Baldus, Marc (07.07.2015). Conformational Plasticity of the POTRA 5 Domain in the Outer Membrane Protein Assembly Factor BamA. Structure with Folding & design, 23 (7), (pp. 1317-1324) (8 p.).
Sinnige, Tessa, Houben, Klaartje, Pritisanac, Iva, Renault, Marie, Boelens, Rolf & Baldus, Marc (2015). Insight into the conformational stability of membrane-embedded BamA using a combined solution and solid-state NMR approach. Journal of Biomolecular NMR, 61 (3-4), (pp. 321-32) (12 p.).
Baker, Lindsay A., Folkers, Gert E., Sinnige, Tessa, Houben, Klaartje, Kaplan, M., van der Cruijsen, Elwin A W & Baldus, Marc (01.01.2015). Magic-Angle-Spinning Solid-State NMR of Membrane Proteins. Methods in Enzymology, 557, (pp. 307-328) (22 p.).
  2010 - Scholarly publications
Jensen, Malene Ringkjøbing, Bernadó, Pau, Houben, Klaartje, Blanchard, Laurence, Marion, Dominque, Ruigrok, Rob W. H. & Blackledge, Martin (30.04.2010). Structural disorder within sendai virus nucleoprotein and phosphoprotein: Insight into the structural basis of molecular recognition. Protein and Peptide Letters, 17 (8), (pp. 952-960) (9 p.).
  2008 - Scholarly publications
Jensen, Malene Ringkjøbing, Houben, Klaartje, Lescop, Ewen, Blanchard, Laurence, Ruigrok, Rob W. H. & Blackledge, Martin (25.06.2008). Quantitative conformational analysis of partially folded proteins from residual dipolar couplings: Application to the molecular recognition element of Sendai virus nucleoprotein. Journal of the American Chemical Society, 130 (25), (pp. 8055-8061) (7 p.).
  2007 - Scholarly publications
Houben, Klaartje, Marion, Dominique, Tarbouriech, Nicolas, Ruigrok, Rob W. H. & Blanchard, Laurence (01.07.2007). Interaction of the C-terminal domains of sendai virus N and P proteins: Comparison of polymerase-nucleocapsid interactions within the paramyxovirus family. Journal of Virology, 81 (13), (pp. 6807-6816) (10 p.).
Houben, Klaartje, Blanchard, Laurence, Blackledge, Martin & Marion, Dominique (01.10.2007). Intrinsic dynamics of the partly unstructured PX domain from the Sendai Virus RNA polymerase cofactor P. Biophysical Journal, 93 (8), (pp. 2830-2844) (15 p.).
Pannetier, Nicolas, Houben, Klaartje, Blanchard, Laurence & Marion, Dominique (01.05.2007). Optimized 3D-NMR sampling for resonance assignment of partially unfolded proteins. Journal of Magnetic Resonance, 186 (1), (pp. 142-149) (8 p.).
  2005 - Scholarly publications
Houben, Klaartje, Wasielewski, Emeric, Dominguez, Cyril, Kellenberger, Esther, Atkinson, R. Andrew, Timmers, H. Th. Marc, Kieffer, Bruno & Boelens, Rolf (10.06.2005). Dynamics and metal exchange properties of C4C4 RING domains from CNOT4 and the p44 subunit of TFIIH. Journal of Molecular Biology, 349 (3), (pp. 621-637) (17 p.).
Bernard, C., Houben, K., Derix, N.M., Marks, D.R.A., van der Horst, M.A., Hellingwerf, K.J., Boelens, R., Kaptein, R. & van Nuland, N.A.J. (2005). The solution structure of a transient photoreceptor intermediate: Δ25-Photoactive Yellow Protein. Structure with Folding & design, 13, (pp. 953-962) (10 p.).
  2004 - Scholarly publications
Houben, K. & Boelens, R. (2004). Side chain dynamics monitored by 13C-13C cross-relaxation. Journal of Biomolecular NMR, 29, (pp. 151-166) (16 p.).
Houben, K., Dominguez, C., van Schaik, F.M.A., Timmers, H.T.M., Bonvin, A.M.J.J. & Boelens, R. (2004). Solution structure of the ubiquitin-conjugating enzyme UbcH5B. Journal of Molecular Biology, 344, (pp. 513-526) (14 p.).
  2001 - Scholarly publications
Bonvin, A.M.J.J., Houben, K., Guenneugues, M.N.L., Kaptein, R. & Boelens, R. (2001). Rapid protein fold determination using secondary chemical shifts and cross-hydrogen bond 15N-13C’ scalar couplings (3hbJNC’). Journal of Biomolecular NMR, 21 (3), (pp. 221-233) (13 p.).
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Gegenereerd op 2018-04-26 15:12:26
Full name
dr. K. Houben Contact details
Nicolaas Bloembergengebouw

Padualaan 12
Room 1.20
3584 CH  UTRECHT
The Netherlands


Phone number (direct) +31 30 253 9940
Phone number (department) +31 30 253 2652
Nicolaas Bloembergengebouw

Padualaan 12
Room 1.20
3584 CH  UTRECHT
The Netherlands


Phone number (direct) +31 30 253 9940
Phone number (department) +31 30 253 2652
Gegenereerd op 2018-04-26 15:12:26
Last updated 07.02.2018