dr. Johanna (Joke) Baas
J.M.P.Baas@uu.nl
Associate Professor
Psychology - Experimental Psychology
Gegenereerd op 2017-09-25 20:36:43


Profile

Joke Baas is experimenteel psycholoog en psychofarmacoloog met een specifieke interesse in angst. Hoe leren mensen angsten aan, en weer af? Welke processen in het brein zijn daarbij betrokken die maken dat sommige mensen banger zijn dan anderen? Wat maakt dat mensen dingen waar ze bang voor waren vermijden, ook als de angst zelf eigenlijk al verdwenen is? Meer kennis over deze vragen kan leiden tot nieuwe ideeen over hoe angst beinvloed kan worden. Een voorbeeld is het nu lopende project waarin onderzocht wordt of cannabidiol (CBD) de uitdoving van angst tijdens cognitieve gedragstherapie gunstig kan beinvloeden. Uit dieronderzoek is al langer bekend dat het cannabinoide systeem (waar ook mariuhana effect op uitoefent) een cruciale rol speelt bij het uitdoven van angst. Het werk van Joke Baas en haar samenwerkingspartners loopt voorop in het vertalen van deze kennis naar een toepassing in de praktijk. Hierin werkt Joke Baas samen met neurowetenschappers. (klinisch) psychologen en psychiaters in binnen en buitenland.

Daarnaast geeft Joke Baas onderwijs in de Bacheloropleiding Psychologie en diverse masteropleidingen en bekleedt zij functies in diverse commissies, waaronder de METC van het Universitair Medisch Centrum Utrecht.

Strategic themes / Focus areas
Scientific expertise
Fear & Anxiety
Fear conditioning
Psychophysiology

We organized the 8th 'European Meeting for Human Fear Conditioning' April 18-20 2016 in Utrecht (Soesterberg).
Gegenereerd op 2017-09-25 20:36:43
All publications
  2016 - Scholarly publications
Duits, P., Cath, D.C., Heitland, I. & Baas, J.M.P. (26.02.2016). High Current Anxiety Symptoms, But Not a Past Anxiety Disorder Diagnosis, are Associated with Impaired Fear Extinction. Frontiers in Psychology, 7, (pp. 1-12).
Heitland, I, Groenink, L, van Gool, J M, Domschke, K, Reif, A & Baas, J M P (2016). Human fear acquisition deficits in relation to genetic variants of the corticotropin releasing hormone receptor 1 and the serotonin transporter - revisited. Genes, Brain and Behavior, 15 (2), (pp. 209-220) (12 p.).
Duits, P., Klein Hofmeijer-Sevink, M., Engelhard, I.M., Baas, J.M.P., Ehrismann, W.A. & Cath, D.C. (2016). Threat expectancy bias and treatment outcome in patients with panic disorder and agoraphobia. Journal of Behavior Therapy and Experimental Psychiatry, 52, (pp. 99-104).
  2015 - Scholarly publications
Klumpers, Floris, Kroes, M., Heitland, I., Everaerd, Daphne, Akkermans, Sophie E.A., Oosting, R.S., van Wingen, Guido, Franke, Barbara, Kenemans, J.L., Fernandez, G. & Baas, J.M.P. (2015). Dorsomedial prefrontal cortex mediates the impact of serotonin transporter linked polymorphic region genotype on anticipatory threat reactions. Biological Psychiatry, 78 (8), (pp. 582-589).
Lonsdorf, Tina & Baas, J.M.P. (2015). Genetics in experimental psychopathology: From laboratory models to therapygenetics. Where do we go from here?. Psychopathology Review, (pp. 1-20).
Bijlsma, Elisabeth Y, Hendriksen, Hendrikus, Baas, Johanna M P, Millan, Mark J & Groenink, Lucianne (2015). Lifelong disturbance of serotonin transporter functioning results in fear learning deficits - Reversal by blockade of CRF1 receptors. European Neuropsychopharmacology, 25 (10), (pp. 1733-1743) (11 p.). Copyright © 2015 Elsevier B.V. and ECNP. All rights reserved..
Baas, J.M.P. & Heitland, I. (2015). The impact of cue learning, trait anxiety and genetic variation in the serotonin 1A receptor on contextual fear. International Journal of Psychophysiology, 98 (3), (pp. 506-514) (9 p.).
Duits, Puck, Cath, Danielle, Lissek, Shmuel, Hox, Joop, Hamm, Alfons, Engelhard, Iris, van den Hout, Marcel & Baas, Joke (20.03.2015). Updated Meta-Analysis of Classical Fear Conditioning in the Anxiety Disorders. Depression and Anxiety, 32 (4), (pp. 239-253).
  2014 - Scholarly publications
Heitland, I., Kenemans, J. L., Böcker, K. B E & Baas, J. M P (01.11.2014). Genetic variability in the human cannabinoid receptor 1 is associated with resting state EEG theta power in humans. Behavioural Brain Research, 274, (pp. 344-348) (5 p.).
Baas, Johanna M P, Klumpers, Floris, Mantione, Mariska H., Figee, Martijn, Vulink, Nienke C., Richard Schuurman, P., Mazaheri, Ali & Denys, Damiaan (09.09.2014). No impact of deep brain stimulation on fear–potentiated startle in obsessive-compulsive disorder. Frontiers in Behavioral Neuroscience, 8 (SEP).
  2013 - Scholarly publications
Heitland, I., Kenemans, J.L., Oosting, R.S., Baas, J.M.P. & Bocker, K.B.E. (2013). Auditory event-related potentials (P3a, P3b) and genetic variants within the dopamine and serotonin system in healthy females. Behavioural Brain Research, 249, (pp. 55-64) (10 p.).
Heitland, Ivo, Groenink, Lucianne, Bijlsma, Elisabeth Y, Oosting, Ronald S & Baas, Johanna M P (2013). Human fear acquisition deficits in relation to genetic variants of the corticotropin releasing hormone receptor 1 and the serotonin transporter. PLoS One, 8 (5).
Sijbrandij, Marit, Engelhard, Iris M, Lommen, Miriam J J, Leer, Arne & Baas, Johanna M P (2013). Impaired fear inhibition learning predicts the persistence of symptoms of posttraumatic stress disorder (PTSD). Journal of Psychiatric Research, 47 (12), (pp. 1991-1997) (7 p.). Copyright © 2013 Elsevier Ltd. All rights reserved..
  2013 - Other output
J.M.P. Baas (22.05.2013) Fear conditioning and context modulation in relation to treatment outcome: a study in treated patients with panic disorder or social phobia
  2012 - Scholarly publications
Heitland, I., Klumpers, F., Oosting, R.S., Evers, D., Kenemans, J.L. & Baas, J.M.P. (2012). Failure to extinguish fear and genetic variability in the human cannabinoid receptor 1. Translational Psychiatry
Heitland, I., Oosting, R.S., Baas, J.M.P., Massar, S., Kenemans, J.L. & Bocker, K.B.E. (2012). Genetic polymorphisms of the dopamine and serotonin systems modulate the neurophysiological response to feedback and risk taking in healthy humans. Cognitive & Behavioral Neurology
Klumpers, F., Heitland, I., Oosting, R.S., Kenemans, J.L. & Baas, J.M.P. (2012). Genetic variation in serotonin transporter function affects human fear expression indexed by fear-potentiated startle. Biological Psychology, 89 (2), (pp. 277-82) (6 p.).
Klumpers, F., Denys, D.A.J.P., Kenemans, J.L., Grillon, C., van der Aart, J. & Baas, J.M.P. (2012). Testing the effects of Δ9-THC and D-cycloserine on extinction of conditioned fear in humans. Journal of Psychopharmacology, 26 (4), (pp. 471-478) (7 p.).
  2011 - Scholarly publications
Kenemans, J.L. & Baas, J.M.P. (2011). Mechanisme van angstreacties en farmacologische beïnvloeding. Psyfar
  2011 - Professional publications
Kenemans, J.L. & Baas, J.M.P. (2011). Angstreacties en farmacologische beinvloeding. Psyfar, 6 (4), (pp. 26-30) (5 p.).
  2010 - Scholarly publications
Massar, S.A.A., Mol, N., Kenemans, J.L. & Baas, J.M.P. (2010). Attentional bias in high- and low-anxious individuals: Evidence for threat-induced effects on engagement and disengagement. Cognition and Emotion (13-10-2010 online), (pp. 1464-0600) (865 p.).
Klumpers, F., van Gerven, J.M., Prinssen, E.P., Niklson, I., Roesch, F., Riedel, J.L., Kenemans, J.L. & Baas, J.M.P. (2010). Method development studies for repeatedly measuring anxiolytic drug effects in healthy humans. Journal of Psychopharmacology, 24 (5), (pp. 657-66) (10 p.).
Klumpers, F., Raemaekers, M.A.H.L.L., Hermans, E.J., Kenemans, J.L. & Baas, J.M.P. (2010). Prefrontal mechanisms of fear reduction after threat offset. Biological Psychiatry, 68 (11), (pp. 1931-8) (8 p.).
  2009 - Scholarly publications
Baas, J.M.P., Mol, N., Kenemans, J.L., Prinssen, E.P., Niklson, I., Xia-Chen, C., Broeyer, F.J.F. & van Gerven, J. (2009). Validating a human model for anxiety using startle potentiated by cue and context: the effects of alprazolam, pregabalin, and diphenhydramine. Psychopharmacology, 205 (1), (pp. 73-84) (12 p.).
  2008 - Scholarly publications
Melis, C., Baas, J.M.P., Kenemans, J.L. & Mangun, G.R. (2008). A decomposition of electrocortical activity as a function of spatial frequency: A weighted multidimensional scaling analysis. Brain Research, 1214, (pp. 116-126) (11 p.).
Hermans, E.J., Putman, P.L.J., Baas, J.M.P., Gecks, N.M., Kenemans, J.L. & Van Honk, E.J. (2008). Exogenous testosterone attenuates the integrated central stress response in healthy young woman. Psychoneuroendocrinology, 32 (8-10), (pp. 1052-1061) (10 p.).
Baas, J.M.P., van Ooijen, L., Goudriaan, A. & Kenemans, J.L. (2008). Failure to condition to a cue is associated with sustained contextual fear. Acta Psychologica, 127 (3), (pp. 581-592) (12 p.).
  2007 - Scholarly publications
Lissek, S., Orme, K., McDowell, J., Johnson, L.L., Luckenbaugh, D.A., Baas, J.M.P., Cornwell, B.R. & Grillon, C. (2007). Emotion regulation and potentiated startle across affective picture and threat-of-shock paradigms. Biological Psychology, 76 (1-2), (pp. 124-133) (10 p.).
Cornwell, B.R., Baas, J.M.P., Johnson, L., Holroyd, T., Carver, F.W., Lissek, S. & Grillon, C. (2007). Neural responses to auditory stimulus deviance under threat of electric shock revealed by spatially-filtered magnetoencephalography. NeuroImage, 37 (1), (pp. 282-289) (8 p.).
Mol, N., Baas, J.M.P., Grillon, C., van Ooijen, L. & Kenemans, J.L. (2007). Startle potentiation in rapidly alternating conditions of high and low predictability of threat. Biological Psychology, 76, (pp. 43-51) (9 p.).
  2006 - Scholarly publications
Hermans, E.J., Putman, P.L.J., Baas, J.M.P., Koppeschaar, H.P.F. & Van Honk, E.J. (2006). A single administration of testosterone reduces fear-potentiated startle in humans. Biological Psychiatry, 59 (9), (pp. 872-874) (3 p.).
Baas, Johanna M P, Milstein, Jean, Donlevy, Meghan & Grillon, Christian (01.04.2006). Brainstem correlates of defensive states in humans. Biological Psychiatry, 59 (7), (pp. 588-93) (6 p.).
Grillon, Christian, Baas, Johanna M P, Cornwell, Brian & Johnson, Linda (2006). Context conditioning and behavioral avoidance in a virtual reality environment - effect of predictability. Biological Psychiatry, 60 (7), (pp. 752-9) (8 p.).
Grillon, Christian, Baas, Johanna M P, Pine, Daniel S, Lissek, Shmuel, Lawley, Megan, Ellis, Valerie & Levine, Jessica (2006). The benzodiazepine alprazolam dissociates contextual fear from cued fear in humans as assessed by fear-potentiated startle. Biological Psychiatry, 60 (7), (pp. 760-6) (7 p.).
  2005 - Scholarly publications
Lisek, S., Baas, J.M.P., Pine, D.S., Orme, K., Dvir, S., Nugent, M., Rosenberger, E., Rawson, E. & Grillon, C. (2005). Airpuff startle probes: an efficacious and less aversive alternative to white-noise. Biological Psychology, 68, (pp. 283-297) (15 p.).
Grillon, C., Pine, D.S., Baas, J.M.P., Lawley, M., Ellis, V. & Charney, D.S. (2005). Cortisol and DHEA-S are associated with startle potentiation during aversive conditioning in humans. Psychopharmacology, 29, (pp. 1-8) (8 p.). Epub ahead of print.
Lissek, Shmuel, Baas, Johanna M P, Pine, Daniel S, Orme, Kaebah, Dvir, Sharone, Rosenberger, Emily & Grillon, Christian (2005). Sensation seeking and the aversive motivational system. Emotion, 5 (4), (pp. 396-407) (12 p.). Copyright (c) 2005 APA, all rights reserved..
  2004 - Scholarly publications
Grillon, C., Baas, J.M.P., Lissek, S. & Milstein, J. (2004). Anxious responses to predictable and unpredictable aversive events. Behavioral Neuroscience, 118 (5), (pp. 916-24) (9 p.).
Böcker, K.B.E., Baas, J.M.P., Kenemans, J.L. & Verbaten, M.N. (2004). Differences in startle modulation during instructed threat and selective attention. Biological Psychology, 67, (pp. 343-358) (16 p.).
Baas, J.M.P., Nugent, M., Lissek, S. & Pine, D.S. (2004). Fear conditioning in virtual reality contexts: a new tool for the study of anxiety. Biological Psychiatry, 55 (11), (pp. 1056-1060) (5 p.).
Böcker, K.B.E., Baas, J.M.P., van Boxtel, G.J.M. & Kenemans, J.L. (2004). Stimulus-preceding negativities as manifestations of affect and attention. Psychophysiology (pp. S6) (1 p.). Congres voordracht.
  2003 - Scholarly publications
Monk, C., Grillon, C., Baas, J.M.P., McClure, E., Nelson, E, Zarahn, E, Charney, D.S., Ernst, M & Pine, D.A. (2003). A neuroimaging method for the study of threat in adolescents. Developmental Psychobiology, 43 ((4)), (pp. 359-366) (8 p.).
Grillon, C. & Baas, J.M.P. (2003). A review of the modulation of the startle reflex by affective states and its application in psychiatry. Clinical Neurophysiology, 114 ((9)), (pp. 1557-1579) (23 p.).
  2002 - Scholarly publications
Baas, J.M.P., Grillon, C., Böcker, K.B.E., Brack, A.A., Morgan III, C.A., Kenemans, J.L. & Verbaten, M.N. (2002). Benzodiazepines have no effect on fear-potentiated startle in humans. Psychopharmacology, 161, (pp. 233-247) (15 p.).
Grillon, C & Baas, J M P (2002). Comments on the use of the startle reflex in psychopharmacological challenges - impact of baseline startle on measurement of fear-potentiated startle. Psychopharmacology, 164 (2), (pp. 236-8) (3 p.).
Baas, J.M.P., Kenemans, J.L. & Mangun, G.R. (2002). Selective attention to spatial frequency: an ERP and source localization analysis. Clinical Neurophysiology, 113, (pp. 1840-1854) (15 p.).
Baas, J.M.P., Kenemans, J.L., Böcker, K.B.E. & Verbaten, M.N. (2002). Threat-induced cortical processing and startle potentiation. NeuroReport, 13 (1), (pp. 133-137) (5 p.).
  2001 - Scholarly publications
Böcker, K.B.E., Baas, J.M.P., Kenemans, J.L., Verbaten, M.N. & Huizenga, H.M. (2001). Electrophysiological manifestations of fear-induced selective attention. Biomedizinische Technik. Biomedical engineering, 46(2), (pp. 239-241) (3 p.).
Böcker, K.B.E., Baas, J.M.P., Kenemans, J.L. & Verbaten, M.N. (2001). Stimulus-Preceding Negativity Induced by Fear: a manifestation of affective anticipation. International Journal of Psychophysiology, 43, (pp. 77-90) (14 p.).
  2000 - Scholarly publications
Kenemans, J.L., Baas, J.M.P., Mangun, G.R., Lijffijt, M. & Verbaten, M.N. (2000). On the processing of spatial frequencies as revealed by evoked-potential source modeling. Clinical Neurophysiology, 111, (pp. 1113-1123) (11 p.).
  1999 - Other output
J.M.P. Baas (18.06.1999) Startle potentiation in an ERP compatible paradigm
  1997 - Professional publications
Baas, J.M.P., Kenemans, J.L. & Verbaten, M.N. (1997). Probing anxiety with the acoustic startle reflex: Potentiation of the human blink reflex by aversive conditioning. Nieuwsbrief Nederlandse Vereniging voor Psychonomie, 12.
  0 - Other output
Baas, J.M.P. 2014 Recipient "Translationeel Onderzoek" - Cannabidiol enhancement of exposure therapy in treatment refractory patients with phobias NWO
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Gegenereerd op 2017-09-25 20:36:43
Full name
dr. J.M.P. Baas Contact details
Martinus J. Langeveldgebouw

Heidelberglaan 1
Room H0.46
3584 CS  UTRECHT
The Netherlands


Phone number (direct) +31 30 253 3018
Phone number (department) +31 30 253 4281
Gegenereerd op 2017-09-25 20:36:44
Last updated 06.06.2016