Publications
2022
Scholarly publications
Thorn-Seshold, O., & Meiring, J. C. M. (2022). Photocontrolling Microtubule Dynamics with Photoswitchable Chemical Reagents. In Microtubules: Methods and Protocols (pp. 403-430). (Methods in Molecular Biology; Vol. 2430). https://doi.org/10.1007/978-1-0716-1983-4_26
Rushworth, J. L., Thawani, A. R., Fajardo-Ruiz, E., Meiring, J. C. M., Heise, C., White, A. J. P., Akhmanova, A., Brandt, J. R., Thorn-Seshold, O., & Fuchter, M. J. (2022). [5]-Helistatins: Tubulin-Binding Helicenes with Antimitotic Activity. JACS Au, 2(11), 2561-2570. https://doi.org/10.1021/jacsau.2c00435
Gao, L., Meiring, J. C. M., Varady, A., Ruider, I. E., Heise, C., Wranik, M., Velasco, C. D., Taylor, J. A., Terni, B., Weinert, T., Standfuss, J., Cabernard, C. C., Llobet, A., Steinmetz, M. O., Bausch, A. R., Distel, M., Thorn-Seshold, J., Akhmanova, A., & Thorn-Seshold, O. (2022). In Vivo Photocontrol of Microtubule Dynamics and Integrity, Migration and Mitosis, by the Potent GFP-Imaging-Compatible Photoswitchable Reagents SBTubA4P and SBTub2M. Journal of the American Chemical Society, 144(12), 5614-5628. https://doi.org/10.1021/jacs.2c01020
Meiring, J. C. M., Grigoriev, I., Nijenhuis, W., Kapitein, L. C., & Akhmanova, A. (2022). Opto-katanin, an optogenetic tool for localized, microtubule disassembly. Current Biology, 32(21), 4660-4674.e6. https://doi.org/10.1016/j.cub.2022.09.010
Gao, L., Meiring, J. C. M., Heise, C., Rai, A., Müller-Deku, A., Akhmanova, A., Thorn-Seshold, J., & Thorn-Seshold, O. (2022). Photoswitchable epothilone-based microtubule stabilisers allow GFP-imaging-compatible, optical control over the microtubule cytoskeleton. Angewandte Chemie-International Edition, 61(10), 1-11. [e202114614]. https://doi.org/10.1002/anie.202114614
2021
Scholarly publications
Sailer, A., Meiring, J. C. M., Heise, C., Pettersson, L. N., Akhmanova, A., Thorn-Seshold, J., & Thorn-Seshold, O. (2021). Pyrrole Hemithioindigo Antimitotics with Near-Quantitative Bidirectional Photoswitching that Photocontrol Cellular Microtubule Dynamics with Single-Cell Precision*. Angewandte Chemie-International Edition, 60(44), 23695-23704. https://doi.org/10.1002/anie.202104794
Gao, L., Meiring, J. C. M., Kraus, Y., Wranik, M., Weinert, T., Pritzl, S. D., Bingham, R., Ntouliou, E., Jansen, K. I., Olieric, N., Standfuss, J., Kapitein, L. C., Lohmüller, T., Ahlfeld, J., Akhmanova, A., Steinmetz, M. O., & Thorn-Seshold, O. (2021). A Robust, GFP-Orthogonal Photoswitchable Inhibitor Scaffold Extends Optical Control over the Microtubule Cytoskeleton. Cell Chemical Biology, 28(2), 228-241.e6. https://doi.org/10.1016/j.chembiol.2020.11.007
https://dspace.library.uu.nl/bitstream/handle/1874/410295/PIIS2451945620304700.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/410295/PIIS2451945620304700.pdf?sequence=1
2020
Scholarly publications
Meiring, J. C. M., & Akhmanova, A. (2020). Microtubules keep large cells in shape. Journal of Cell Biology, 219(6). https://doi.org/10.1083/jcb.202004031
Müller-Deku, A., Meiring, J. C. M., Loy, K., Kraus, Y., Heise, C., Bingham, R., Jansen, K. I., Qu, X., Bartolini, F., Kapitein, L. C., Akhmanova, A., Ahlfeld, J., Trauner, D., & Thorn-Seshold, O. (2020). Photoswitchable paclitaxel-based microtubule stabilisers allow optical control over the microtubule cytoskeleton. Nature Communications, 11, [4640]. https://doi.org/10.1038/s41467-020-18389-6
Meiring, J. C. M., Shneyer, B. I., & Akhmanova, A. (2020). Generation and regulation of microtubule network asymmetry to drive cell polarity. Current Opinion in Cell Biology, 62, 86-95. https://doi.org/10.1016/j.ceb.2019.10.004