Publications
2023
Scholarly publications
Teunissen, M., Meij, B. P., Snel, L., Coeleveld, K., Popov-Celeketic, J., Ludwig, I. S., Broere, F., Lafeber, F. P. J. G., Tryfonidou, M. A., & Mastbergen, S. C. (2023). The catabolic-to-anabolic shift seen in the canine osteoarthritic cartilage treated with knee joint distraction occurs after the distraction period. Journal of Orthopaedic Translation, 38, 44-55. https://doi.org/10.1016/j.jot.2022.09.003
2022
Scholarly publications
Novak, A., Hindriks, E., Hoek, A., Veraart, C., Broens, E. M., Ludwig, I., Rutten, V., Sloots, A., & Broere, F. (2023). Cellular and humoral immune responsiveness to inactivated Leptospira interrogans in dogs vaccinated with a tetravalent Leptospira vaccine. Vaccine. https://doi.org/10.1016/j.vaccine.2022.11.017
Teunissen, M., Mastbergen, S. C., Spoelman, D., Lafeber, F., Ludwig, I., Broere, F., Tryfonidou, M., & Meij, B. (2022). Knee Joint Distraction in a Dog as Treatment for Severe Osteoarthritis. VCOT Open, 5(1), e11-e17. https://doi.org/10.1055/s-0042-1742471
Novak, A., Pennings, J. L., van der Maas, L., Meiring, H. D., Ludwig, I., Rutten, V. P. M. G., Verkoeijen, S., Broere, F., & Sloots, A. (2022). Transcriptome and proteome analysis of innate immune responses to inactivated Leptospira and bivalent Leptospira vaccines in canine 030-D cells. Scientific Reports, 12(1), 1-14. [13418]. https://doi.org/10.1038/s41598-022-16457-z
2020
Scholarly publications
Lyu, Q., Ludwig, I. S., Kooten, P. J. S., Sijts, A. J. A. M., Rutten, V. P. M. G., van Eden, W., & Broere, F. (2020). Leucinostatin acts as a co-inducer for heat shock protein 70 in cultured canine retinal pigment epithelial cells. Cell Stress & Chaperones, 25, 235-243. https://doi.org/10.1007/s12192-019-01066-z
2019
Scholarly publications
Jansen, M. A. A., Spiering, R., Ludwig, I. S., van Eden, W., Hilkens, C. M. U., & Broere, F. (2019). Matured Tolerogenic Dendritic Cells Effectively Inhibit Autoantigen Specific CD4+ T Cells in a Murine Arthritis Model. Frontiers in Immunology, 10, [2068]. https://doi.org/10.3389/fimmu.2019.02068
van Eden, W., Jansen, M. A. A., Ludwig, I. S., Leufkens, P., van der Goes, M. C., van Laar, J. M., & Broere, F. (2019). Heat Shock Proteins Can Be Surrogate Autoantigens for Induction of Antigen Specific Therapeutic Tolerance in Rheumatoid Arthritis. Frontiers in Immunology, 10, [279]. https://doi.org/10.3389/fimmu.2019.00279
2018
Scholarly publications
Ludwig, I. S., Broere, F., Manurung, S., Lambers, T. T., van der Zee, R., & van Eden, W. (2018). Lactobacillus rhamnosus GG-derived soluble mediators modulate adaptive immune cells. Frontiers in Immunology, 9, 1-6. [1546]. https://doi.org/10.3389/fimmu.2018.01546
van Aalst, S., Jansen, M. A. A., Ludwig, I. S., van der Zee, R., van Eden, W., & Broere, F. (2018). Routing dependent immune responses after experimental R848-adjuvated vaccination. Vaccine, 36(11), 1405-1413. https://doi.org/10.1016/j.vaccine.2018.01.077
2017
Scholarly publications
van Eden, W., Jansen, M. A. A., de Wolf, A. C. M., Ludwig, I. S., Leufkens, P., & Broere, F. (2017). The Immunomodulatory Potential of tolDCs Loaded with Heat Shock Proteins. Frontiers in Immunology, 8, [1690]. https://doi.org/10.3389/fimmu.2017.01690
van Eden, W., Jansen, M. A. A., Ludwig, I., van Kooten, P., van der Zee, R., & Broere, F. (2017). The Enigma of Heat Shock Proteins in Immune Tolerance. Frontiers in Immunology, 8, [1599]. https://doi.org/10.3389/fimmu.2017.01599
de Wolf, A. C. M. T., van Aalst, S., Ludwig, I. S., Bodinham, C. L., Lewis, D. J., van der Zee, R., van Eden, W., & Broere, F. (2017). Regulatory T cell frequencies and phenotypes following anti-viral vaccination. PLoS One, 12(6), [e0179942]. https://doi.org/10.1371/journal.pone.0179942
van Aalst, S., Ludwig, I. S., van Kooten, P. J. S., van der Zee, R., van Eden, W., & Broere, F. (2017). Dynamics of APC recruitment at the site of injection following injection of vaccine adjuvants. Vaccine, 35(12), 1622-1629. https://doi.org/10.1016/j.vaccine.2017.02.005
van Aalst, S., Ludwig, I. S., van der Zee, R., van Eden, W., & Broere, F. (2017). Bystander activation of irrelevant CD4+ T cells following antigen-specific vaccination occurs in the presence and absence of adjuvant. PLoS One, 12(5), 1-13. https://doi.org/10.1371/journal.pone.0177365
2016
Scholarly publications
Kwast, L., Aida, T., Fiechter, D., Kruijssen, L., Bleumink, R., Boon, L., Ludwig, I., & Pieters, R. (2016). Immune responses induced by diclofenac or carbamazepine in an oral exposure model using TNP-Ficoll as reporter antigen. Journal of Immunotoxicology, 13(6), 918-926. https://doi.org/10.1080/1547691X.2016.1247929
De Wolf, C., Van Der Zee, R., Den Braber, I., Glant, T., Maill??re, B., Favry, E., Van Lummel, M., Koning, F., Hoek, A., Ludwig, I., Van Eden, W., & Broere, F. (2016). An Arthritis-Suppressive and Treg Cell-Inducing CD4+ T Cell Epitope is Functional in the Context of HLA-Restricted T Cell Responses. In Arthritis and Rheumatology (pp. 639-647). (Arthritis and Rheumatology; Vol. 68, No. 3). John Wiley and Sons Inc.. https://doi.org/10.1002/art.39444
Kwast, L., Fiechter, D., Kruijssen, L., Bleumink, R., Ludwig, I., Bol-Schoenmakers, M., Smit, J., & Pieters, R. (2016). Oral exposure to immunostimulating drugs results in early changes in innate immune parameters in the spleen. Journal of Immunotoxicology, 13(4), 535-47. https://doi.org/10.3109/1547691X.2016.1139643
2011
Scholarly publications
Bol-Schoenmakers, M., Bleumink, R., Marcondes Rezende, M., Mouser, E., Hassing, I., Ludwig, I. S., Smit, J. J., & Pieters, R. H. H. (2011). Diclofenac enhances allergic responses in a mouse peanut allergy model. Clinical and Experimental Allergy, 41(3), 424-433. https://doi.org/10.1111/j.1365-2222.2010.03594.x
Kwast, L. M., Fiechter, D., Hassing, I., Bleumink, R., Boon, L., Ludwig, I. S., & Pieters, R. H. H. (2011). Oral exposure to drugs with immune-adjuvant potential induces hypersensitivity responses to the reporter antigen TNP-OVA. Toxicological Sciences, 121(2), 312-319. https://doi.org/10.1093/toxsci/kfr052
2010
Scholarly publications
Ludwig, I. S., Kwast, L. M., Fiechter, D., & Pieters, R. H. H. (2010). An in vivo tiered approach to test immunosensitization by low molecular weight compounds. Methods in Molecular Biology, 598(Part 2), 27-37. https://doi.org/10.1007/978-1-60761-401-2_3
Pieters, R., & Ludwig, I. S. (2010). Chemically Induced Allergy and Autoimmunity. In C. A. McQueen (Ed.), Comprehensive Toxicology, volume 5 (pp. 361-374). Academic Press Inc..
2008
Scholarly publications
op den Brouw, M. L., de Jong, M. A., Ludwig, I. S., Molen, R. G., Janssen, H. L. A., Geijtenbeek, T. B. H., & Woltman, A. M. (2008). Branched oligosaccharide structures on HBV prevent interaction with both DC-SIGN and L-SIGN. Journal of Viral Hepatitis, 15(9), 675-683.