Dr. H. (Hilde) Aardema

Jeannette Donker-Voetgebouw
Yalelaan 104-106
Kamer 2.050
3584 CM Utrecht

Dr. H. (Hilde) Aardema

Associate Professor
Farm Animal Health
+31 30 253 1130
h.aardema@uu.nl

Publications

2025

Scholarly publications

Aardema, H., Vos, P. L. A. M., Luciano, A. M., & Buratini, J. (2025). Metabolic and endocrinologic interplay in the peri-ovulatory follicle to support the cumulus-oocyte-complex towards full competence. Animal Reproduction, 22(3), e20250067. [DOI]
Wicaksono, A., van den Borne, B. H. P., Aardema, H., van Werven, T., Hogeveen, H., & Steeneveld, W. (2025). Estimating the costs of interrelated reproductive disorders in dairy farms. Journal of Dairy Science, 108(8), 8508-8528. [DOI] [Portal]
Piscopo, F., Gasparrini, B., van Halderen, R., Brouwers, J. F., van den Broek, J., van Tol, H. T. A., Vos, P. L. A. M., & Aardema, H. (2025). Periparturient oleic acid-rich fat supplementation affects the lipid profile in blood and results in an increased oocyte yield in postpartum dairy cows. Theriogenology, 236, 33-44. [DOI] [Portal]
Krystek, P., Koelmans, A. A., Quik, J., Swart, E., Krause, S., Legler, J., Aardema, H., & Vethaak, D. (2025). Micro-and nanoplastics in soil: New insights, knowledge gaps and challenges. Chemosphere, 373, Article 144117. [DOI] [Portal]

2024

Scholarly publications

Aardema, H., Vethaak, A. D., Kamstra, J. H., & Legler, J. (2024). Farm animals as a critical link between environmental and human health impacts of micro-and nanoplastics. Microplastics and Nanoplastics, 4(1), Article 5. [DOI] [Repository]
Chen, Y., Steeneveld, W., Frankena, K., Leemans, I., Aardema, H., Vos, P. L. A. M., Nielen, M., & Hostens, M. (2024). Association between days post conception and lactation persistency in dairy cattle. Journal of Dairy Science, 107(8), 5794-5804. [DOI] [Portal]

2023

Scholarly publications

Yang, J., Kamstra, J., Legler, J., & Aardema, H. (2023). The impact of microplastics on female reproduction and early life. Animal Reproduction, 20(2), 1-14. Article e20230037. [DOI] [Repository]
Kosior, M. A., Esposito, R., Cocchia, N., Piscopo, F., Longobardi, V., Cacciola, N. A., Presicce, G. A., Campanile, G., Aardema, H., & Gasparrini, B. (2023). Seasonal variations in the metabolomic profile of the ovarian follicle components in Italian Mediterranean Buffaloes. Theriogenology, 202, 42-50. [DOI] [Repository]

2022

Scholarly publications

Kosior, M. A., Calabria, A., Benitez Mora, M. P., Russo, M., Presicce, G. A., Cocchia, N., Monti, S., Aardema, H., & Gasparrini, B. (2022). Seasonal Variations in the Lipid Profile of the Ovarian Follicle in Italian Mediterranean Buffaloes. Animals, 12(16), 1-12. Article 2108. [DOI] [Repository]
Aardema, H., Bertijn, I., van Tol, HTA., Rijneveld, A., Vernooij, JCM., Gadella, B. M., & Vos, PLAM. (2022). Fatty Acid Supplementation During in vitro Embryo Production Determines Cryosurvival Characteristics of Bovine Blastocysts. Frontiers in Cell and Developmental Biology, 10, 1-14. Article 837405. [DOI] [Repository]
Manalili, D., Berardi, M., Aardema, H., Asimaki, K., Sarmiento, R., & Avci, I. (2022). Parallel-plate compression test for soft materials: confocal microscopy-assisted ferrule-top nanoindentation. Biomedical Optics Express, 13(2), 824-837. [DOI] [Repository]

2021

Scholarly publications

Scheurwater, J., Jorritsma, R., Nielen, M., Heesterbeek, H., van den Broek, J., & Aardema, H. (2021). The effects of cow introductions on milk production and behaviour of the herd measured with sensors. Journal of Dairy Research, 88(4), 374-380. [DOI] [Repository]
Berardi, M., Bielawski, K., Rijnveld, N., Gruca, G., Aardema, H., van Tol, L., Wuite, G., & Acka, I. B. (2021). Interferometry-based Micropipette Aspiration Allows to Study of the Nanoscale Dynamic Mechanical Behavior of Biomaterials. In A. Amelink, S. K. Nadkarni, & G. Scarcelli (Eds.), Proc. SPIE 11921, Emerging Technologies for Cell and Tissue Characterization Article 119210A Society of Photo-Optical Instrumentation Engineers (SPIE) and The Optical Society. [DOI]
van der Laan, J. S. M., Vos, P. L. A. M., van den Borne, B. H. P., Aardema, H., & van Werven, T. (2021). Reproductive hormone use and its association with herd-level factors on Dutch dairy farms. Journal of Dairy Science, 104(10), 10854-10862. [DOI] [Repository]
Scheurwater, J., Hostens, M., Nielen, M., Heesterbeek, H., Schot, A., van Hoeij, R., & Aardema, H. (2021). Pressure measurement in the reticulum to detect different behaviors of healthy cows. PLoS One, 16(7), 1-13. Article e0254410. [DOI] [Repository]
Berardi, M., Bielawski, K., Rijnveld, N., Gruca, G., Aardema, H., van Tol, L., Wuite, G., & Akca, B. I. (2021). Optical interferometry based micropipette aspiration provides real-time sub-nanometer spatial resolution. Communications Biology, 4(1), 1-7. Article 610. [DOI] [Repository]

2020

Scholarly publications

Aardema, H., Van Tol, H. T. A., & Vos, P. L. A. M. (2020). 196 Steroid concentrations in bovine follicular fluid are affected by metabolic stress. Reproduction, Fertility and Development, 32(2), 226. [DOI]

2019

Scholarly publications

Aardema, H., van Tol, H. T. A., & Vos, P. L. A. M. (2019). An overview on how cumulus cells interact with the oocyte in a condition with elevated NEFA levels in dairy cows. Animal Reproduction Science, 207, 131-137. [DOI] [Repository]

2018

Scholarly publications

Aardema, H., Vos, P. L. A. M., & Gadella, B. M. (2018). Cumulus cells protect the oocyte against saturated free fatty acids. Animal Reproduction, 15(Supplement 1), 737-750. [DOI] [Repository]

2017

Scholarly publications

Aardema, H., van Tol, H. T. A., Wubbolts, R. W., Brouwers, J. F. H. M., Gadella, B. M., & Roelen, B. A. J. (2017). Stearoyl-CoA desaturase activity in bovine cumulus cells protects the oocyte against saturated fatty acid stress. Biology of Reproduction, 96(5), 982-992. [DOI] [Repository]

2015

Scholarly publications

Aardema, H., Gadella, B. M., van de Lest, C. H. A., Brouwers, J. F. H. M., Stout, T. A. E., Roelen, B. A. J., & Vos, P. L. A. M. (2015). Free fatty acid levels in fluid of dominant follicles at the preferred insemination time in dairy cows are not affected by early postpartum fatty acid stress. Journal of Dairy Science, 98(4), 2322-2336. [DOI] [Repository]
Lolicato, F., Brouwers, J. F., van de Lest, C. H. A., Wubbolts, R., Aardema, H., Priore, P., Roelen, B. A. J., Helms, J. B., & Gadella, B. M. (2015). The Cumulus Cell Layer Protects Bovine Maturing Oocyte Against Fatty Acid-Induced Lipotoxicity. Biology of Reproduction, 92(1), 1-16. Article 16. [DOI] [Repository]

2014

Scholarly publications

Aardema, H. (2014). Impact of free fatty acid composition on oocyte developmental competence in dairy cows. [Doctoral thesis 1 (Research UU / Graduation UU), Utrecht University]. Utrecht University. [Repository]

2013

Scholarly publications

Aardema, H., Lolicato, F., Roelen, B. A. J., Vos, P. L. A. M., Helms, J. B., & Gadella, B. M. (2013). Cumulus cells protect oocytes against potential lipotoxicity from elevated free fatty acid concentrations in follicular fluid. Reproduction Fertility and Development, 25(1), 148-148. [DOI]
Aardema, H., Roelen, B. A. J., van Tol, H. T. A., Oei, C. H. Y., Gadella, B. M., & Vos, P. L. A. M. (2013). Follicular 17β-estradiol and progesterone concentrations and degree of cumulus cell expansion as predictors of in vivo-matured oocyte developmental competence in superstimulated heifers. Theriogenology, 80(6), 576-83. [DOI]
Aardema, H., Lolicato, F., van de Lest, C. H. A., Brouwers, J. F., Vaandrager, A. B., van Tol, H. T. A., Roelen, B. A. J., Vos, P. L. A. M., Helms, J. B., & Gadella, B. M. (2013). Bovine cumulus cells protect maturing oocytes from increased fatty acid levels by massive intracellular lipid storage. Biology of Reproduction, 88(6), 1-15. [DOI] [Repository]

2011

Scholarly publications

Aardema, H., Roelen, B. A. J., Gadella, B. M., & Vos, P. L. A. M. (2011). Metabolic stress impairs follicular growth in superovulated heifers. Reproduction Fertility and Development, 23(1), 189-189. [DOI]
Aardema, H., Vos, P. L. A. M., Lolicato, F., Roelen, B. A. J., Knijn, H. M., Vaandrager, A. B., Helms, J. B., & Gadella, B. M. (2011). Oleic Acid Prevents Detrimental Effects of Saturated Fatty Acids on Bovine Oocyte. Biology of Reproduction, 85(1), 62-69. [Repository]

2010

Scholarly publications

Aardema, H., Vos, P., Knijn, H., Roelen, B., & Gadella, B. (2010). Unsaturated and saturated non-esterified fatty acids differently affect lipid storage and developmental competence of bovine oocytes. Reproduction Fertility and Development, 22(1), 319-320. [DOI]

2009

Scholarly publications

Aardema, H., Vos, P. L. A. M., Roelen, B. A. J., Knijn, H. M., & Gadella, B. M. (2009). Developmental competence and lipid droplet features of maturing bovine oocytes are affected by saturated and not by unsaturated fatty acids. Reproduction in Domestic Animals, 44, 81-81.

2008

Scholarly publications

Aardema, H., Knijn, H. M., Oei, C. H. Y., Vos, P. L. A. M., & Gadella, B. M. (2008). Lipid Droplet Dynamics during In Vitro Maturation of Bovine Oocytes. Reproduction in Domestic Animals, 43, 76-76.