dr. E. (Enrico) Mastrobattista
e.mastrobattista@uu.nl
Gegenereerd op 2017-11-19 08:09:52


Profile

Involved in the following study programme(s)
Scientific expertise
Preparation and characterization of nanoparticles for nucleic acid and protein delivery into cells
Skills
Liposome preparation
Particle Sizing
High content imaging
Protein production
Gegenereerd op 2017-11-19 08:09:52
All publications
  2017 - Scholarly publications
Guan, J., Sun, J., Sun, F., Lou, B., Zhang, D., Mashayekhi, V., Sadeghi, N., Storm, G., Mastrobattista, E. & He, Z. (06.07.2017). Hypoxia-induced tumor cell resistance is overcome by synergistic GAPDH-siRNA and chemotherapy co-delivered by long-circulating and cationic-interior liposomes. Nanoscale, 9 (26), (pp. 9190-9201 ).
Tüysüz, Nesrin, van Bloois, Louis, van den Brink, Stieneke, Begthel, Harry, Verstegen, Monique M A, Cruz, Luis J, Hui, Lijian, van der Laan, Luc J W, de Jonge, Jeroen, Vries, Robert, Braakman, Eric, Mastrobattista, Enrico, Cornelissen, Jan J, Clevers, Hans & Ten Berge, Derk (2017). Lipid-mediated Wnt protein stabilization enables serum-free culture of human organ stem cells. Nature Communications, 8.
Schellekens, Huub, Aldosari, Mohammed, Talsma, Herre & Mastrobattista, Enrico (05.06.2017). Making individualized drugs a reality. Nature Biotechnology, 35 (6), (pp. 507-513).
Li, Dandan, Chen, Yinan, Mastrobattista, Enrico, Van Nostrum, Cornelus F., Hennink, Wim E. & Vermonden, Tina (2017). Reduction-sensitive polymer-shell-coated nanogels for intracellular delivery of antigens. ACS Biomaterials Science and Engineering, 3 (1), (pp. 42-48) (7 p.).
Radmalekshahi, Mazda, Fransen, Marieke F, Krawczyk, MaƂgorzata, Mansourian, Mersedeh, Bourajjaj, Meriem, Chen, Jian, Ossendorp, Ferry, Hennink, Wim E, Mastrobattista, Enrico & Amidi, Maryam (27.01.2017). Self-Assembling Peptide Epitopes as Novel Platform for Anticancer Vaccination. Molecular Pharmaceutics, 14, (pp. 1482-1493).
Oude Blenke, E., Sleszynska, M., Evers, M. J W, Storm, G., Martin, Nathaniel & Mastrobattista, E. (15.02.2017). Strategies for the Activation and Release of the Membranolytic Peptide Melittin from Liposomes Using Endosomal pH as a Trigger. Bioconjugate Chemistry, 28 (2), (pp. 574-582) (9 p.).
  2016 - Scholarly publications
Radmalekshahi, Mazda, Lempsink, Ludwijn, Amidi, Maryam, Hennink, Wim E. & Mastrobattista, Enrico (20.01.2016). Biomedical Applications of Self-Assembling Peptides. Bioconjugate Chemistry, 27 (1), (pp. 3-18) (16 p.).
Oude Blenke, Erik E., Van Den Dikkenberg, Joep, Van Kolck, Bartjan, Kros, Alexander & Mastrobattista, Enrico (28.04.2016). Coiled coil interactions for the targeting of liposomes for nucleic acid delivery. Nanoscale, 8 (16), (pp. 8955-8965) (11 p.).
Oude Blenke, Erik, Evers, Martijn J W, Mastrobattista, Enrico & van der Oost, John (04.08.2016). CRISPR-Cas9 gene editing - Delivery aspects and therapeutic potential. Journal of Controlled Release
Janssen, Manoe J, Arcolino, Fanny O, Schoor, Perry, Kok, Robbert Jan & Mastrobattista, Enrico (22.07.2016). Gene based therapies for kidney regeneration. European Journal of Pharmacology, 790, (pp. 99-108). Copyright © 2016. Published by Elsevier B.V..
Li, Dandan, van Nostrum, Cornelus F, Mastrobattista, Enrico, Vermonden, Tina & Hennink, Wim E (23.12.2016). Nanogels for intracellular delivery of biotherapeutics. Journal of Controlled Release Copyright © 2016 Elsevier B.V. All rights reserved..
  2015 - Scholarly publications
Novo, Luís, Mastrobattista, Enrico, Van Nostrum, Cornelus F., Lammers, Twan & Hennink, Wim E. (01.01.2015). Decationized polyplexes for gene delivery. Expert Opinion on Drug Delivery, 12 (4), (pp. 507-512) (6 p.).
Oude Blenke, Erik, Klaasse, Gruson, Merten, Hannes, Plückthun, Andreas, Mastrobattista, Enrico & Martin, Nathaniel I. (28.03.2015). Liposome functionalization with copper-free "click chemistry". Journal of Controlled Release, 202, (pp. 14-20) (7 p.).
Maas, Sybren L N, De Vrij, Jeroen, Van Der Vlist, Els J., Geragousian, Biaina, Van Bloois, Louis, Mastrobattista, Enrico, Schiffelers, Raymond M., Wauben, Marca H M, Broekman, Marike L D & Nolte-'T Hoen, Esther N M (28.02.2015). Possibilities and limitations of current technologies for quantification of biological extracellular vesicles and synthetic mimics. Journal of Controlled Release, 200, (pp. 87-96) (10 p.).
Novo, Luís, Takeda, Kaori M., Petteta, Tamara, Dakwar, George R., Van Den Dikkenberg, Joep B., Remaut, Katrien, Braeckmans, Kevin, Van Nostrum, Cornelus F., Mastrobattista, Enrico & Hennink, Wim E. (05.01.2015). Targeted decationized polyplexes for siRNA delivery. Molecular Pharmaceutics, 12 (1), (pp. 150-161) (12 p.).
Radmalekshahi, Mazda, Visscher, Koen M., Garcia Lopes Maia Rodrigues, João, De Vries, Renko, Hennink, Wim E., Baldus, Marc, Bonvin, Alexandre M J J, Mastrobattista, Enrico & Weingarth, Markus (24.06.2015). The Supramolecular Organization of a Peptide-Based Nanocarrier at High Molecular Detail. Journal of the American Chemical Society, 137 (24), (pp. 7775-7784) (10 p.).
Duinhouwer, Lucia E., Tüysüz, Nesrin, Rombouts, Elwin W J C, Ter Borg, Mariette N D, Mastrobattista, Enrico, Spanholtz, Jan, Cornelissen, Jan J., Berge, Derk Ten & Braakman, Eric (25.03.2015). Wnt3a protein reduces growth factor-driven expansion of human hematopoietic stem and progenitor cells in serum-free cultures. PLoS One, 10 (3).
  2014 - Scholarly publications
Yousefi, Afrouz, Bourajjaj, Meriem, Babae, Negar, Noort, Paula I Van, Schaapveld, Roel Q J, Beijnum, Judy R Van, Griffioen, Arjan W., Storm, Gert, Schiffelers, Raymond M. & Mastrobattista, Enrico (10.09.2014). Anginex lipoplexes for delivery of anti-angiogenic siRNA. International Journal of Pharmaceutics, 472 (1-2), (pp. 175-184) (10 p.).
Novo, Luís, Rizzo, Larissa Y., Golombek, Susanne K., Dakwar, George R., Lou, Bo, Remaut, Katrien, Mastrobattista, Enrico, Van Nostrum, Cornelus F., Jahnen-Dechent, Wilhelm, Kiessling, Fabian, Braeckmans, Kevin, Lammers, Twan & Hennink, Wim E. (10.12.2014). Decationized polyplexes as stable and safe carrier systems for improved biodistribution in systemic gene therapy. Journal of Controlled Release, 195, (pp. 162-175) (14 p.).
Lanzi, Anastasia, Fehres, Cynthia M., De Gruijl, Tanja D., Van Kooyk, Yvette & Mastrobattista, Enrico (01.02.2014). Effects of antigen-expressing immunostimulatory liposomes on chemotaxis and maturation of dendritic cells in vitro and in human skin explants. Pharmaceutical Research, 31 (2), (pp. 516-526) (11 p.).
Yousefi, Afrouz, Lauwers, Marianne, Nemes, Reka, van Holten, Thijs, Babae, Negar, Roest, Mark, Storm, Gert, Schiffelers, Raymond & Mastrobattista, Enrico (20.05.2014). Hemocompatibility Assessment of two siRNA Nanocarrier Formulations. Pharmaceutical Research, 31 (11), (pp. 3127-3135) (9 p.).
Rad-Malekshahi, Mazda, Flement, Matthias, Hennink, Wim E. & Mastrobattista, Enrico (31.12.2014). Optimization of the recombinant production and purification of a self-assembling peptide in Escherichia coli. Microbial Cell Factories, 13 (1).
Babae, Negar, Bourajjaj, Meriem, Liu, Yijia, Van Beijnum, Judy R., Cerisoli, Francesco, Scaria, Puthupparampil V., Verheul, Mark, Van Berkel, Maaike P., Pieters, Ebel H E, Van Haastert, Rick J., Yousefi, Afrouz, Mastrobattista, Enrico, Storm, Gert, Berezikov, Eugene, Cuppen, Edwin, Woodle, Martin, Schaapveld, Roel Q J, Prevost, Gregoire P., Griffioen, Arjan W., Van Noort, Paula I. & Schiffelers, Raymond M. (01.01.2014). Systemic miRNA-7 delivery inhibits tumor angiogenesis and growth in murine xenograft glioblastoma. Oncotarget, 5 (16), (pp. 6687-6700) (14 p.).
Novo, Luiìs, Mastrobattista, Enrico, Van Nostrum, Cornelus F. & Hennink, Wim E. (16.04.2014). Targeted decationized polyplexes for cell specific gene delivery. Bioconjugate Chemistry, 25 (4), (pp. 802-812) (11 p.).
  2013 - Scholarly publications
de Raad, M., Kooijmans, S.A.A., Teunissen, E.A. & Mastrobattista, E. (2013). A Solid-Phase Platform for Combinatorial and Scarless Multipart Gene Assembly. ACS Synthetic Biology, 2 (6), (pp. 316-326) (11 p.).
Mastrobattista, E. (2013). Advanced drug delivery in motion. International Journal of Pharmaceutics, 454 (1), (pp. 517-20) (4 p.).
Mastrobattista, E. (2013). Artificial microbes to fight cancer. Nanomedicine, 8 (1), (pp. 5-7) (3 p.).
Novo, L., van Gaal, E.V.B., Mastrobattista, E., van Nostrum, C.F. & Hennink, W.E. (2013). Decationized crosslinked polyplexes for redox-triggered gene delivery. Journal of Controlled Release, 169 (3), (pp. 246-56) (11 p.).
Teunissen, E.A., de Raad, M. & Mastrobattista, E. (2013). Production and biomedical applications of virus-like particles derived from polyomaviruses. Journal of Controlled Release, 172 (1), (pp. 305-21) (17 p.).
Oude Blenke, E., Mastrobattista, E. & Schiffelers, R.M. (2013). Strategies for triggered drug release from tumor targeted liposomes. Expert Opinion on Drug Delivery, 10 (10), (pp. 1399-410) (12 p.).
Yousefi, A., Storm, G., Schiffelers, R.M. & Mastrobattista, E. (2013). Trends in polymeric delivery of nucleic acids to tumors. Journal of Controlled Release, 170 (2), (pp. 209-18) (10 p.).
  2012 - Scholarly publications
de Graaf, A.J., Azevedo Próspero dos Santos, I.I., Pieters, E.H.E., Rijkers, D.T.S., van Nostrum, C.F., Vermonden, T., Kok, R.J., Hennink, W.E. & Mastrobattista, E. (2012). A micelle-shedding thermosensitive hydrogel as sustained release formulation. Journal of Controlled Release, 162, (pp. 582-590) (9 p.).
Verheul, R.J., Hagenaars, N., van Es, T., van Gaal, E.V.B., de Jong, P.H.J.L.F, Bruijns, S., Mastrobattista, E., Slutter, B., Que, I., Heldens, J.G., van den Bosch, H., Glansbeek, H.L., Hennink, W.E. & Jiskoot, W. (2012). A step-by-step approach to study the influence of N-acetylation on the adjuvanticity of N,N,N-trimethyl chitosan (TMC) in an intranasal nanoparticulate influenza virus vaccine. European Journal of Pharmaceutical Sciences, 45 (4), (pp. 467-74) (8 p.).
van Rooy, I., Hennink, W.E., Storm, G., Schiffelers, R.M. & Mastrobattista, E. (2012). Attaching the phage display-selected GLA peptide to liposomes: factors influencing target binding. European Journal of Pharmaceutical Sciences, 45 (3), (pp. 330-5) (6 p.).
de Raad, M., Teunissen, E.A., Lelieveld, D., Egan, D.A. & Mastrobattista, E. (2012). High-content screening of peptide-based non-viral gene delivery systems. Journal of Controlled Release, 158 (3), (pp. 433-442) (10 p.).
Amidi, M., van Helden, M.J.G., Tabataei, N.R., de Goede, A.L., Schouten, M., de Bot, V., Lanzi, A.J.E., Gruters, R.A., Rimmelzwaan, G.F., Sijts, E.J.A.M. & Mastrobattista, E. (2012). Induction of humoral and cellular immune responses by antigen-expressing immunostimulatory liposomes. Journal of Controlled Release, 164, (pp. 323-330) (8 p.).
Mastrobattista, E. & Hennink, W.E. (2012). Polymers for gene delivery: charged for success. Nature Materials, (pp. 10-12) (3 p.).
Joshi, M.D., Unger, W.J., Storm, G., van Kooyk, Y. & Mastrobattista, E. (2012). Targeting tumor antigens to dendritic cells using particulate carriers. Journal of Controlled Release, 161 (1), (pp. 25-37) (13 p.).
de Graaf, A.J., Mastrobattista, E., Vermonden, T., van Nostrum, C.F., Rijkers, D.T.S., Liskamp, R.M.J. & Hennink, W.E. (2012). Thermosensitive peptide-hybrid ABC block copolymers obtained by ATRP: synthesis, self assembly, and enzymatic degradation. Macromolecules, 45, (pp. 842-851) (10 p.).
  2011 - Scholarly publications
Amidi, M., de Raad, M., Crommelin, D.J.A., Hennink, W.E. & Mastrobattista, E. (2011). Antigen-expressing immunostimulatory liposomes as a genetically programmable synthetic vaccine. Systems and Synthetic Biology, 5 (1-2), (pp. 21-31) (11 p.).
de Graaf, A.J., Mastrobattista, E., van Nostrum, C.F., Rijkers, D.T.S., Hennink, W.E. & Vermonden, T. (2011). ATRP, subsequent azide substitution and "click" chemistry: three reactions using one catalyst in a one-pot. Chemical Communications, 47, (pp. 6972-6974) (3 p.).
van Rooy, I., Mastrobattista, E., Storm, G., Hennink, W.E. & Schiffelers, R.M. (2011). Comparison of five different targeting ligands to enhance accumulation of liposomes into the brain. Journal of Controlled Release, 150, (pp. 30-36) (7 p.).
van Gaal, E.V.B., Oosting, R.S., van Eijk, R., Bakowska, M., Feyen, D., Kok, R.J., Hennink, W.E., Crommelin, D.J.A. & Mastrobattista, E. (2011). DNA nuclear targeting sequences for non-viral gene delivery. Pharmaceutical Research, 28 (7), (pp. 1707-22) (16 p.).
van Gaal, E.V.B., van Eijk, R., Oosting, R.S., Kok, R.J., Hennink, W.E., Crommelin, D.J.A. & Mastrobattista, E. (2011). How to screen non-viral gene delivery systems in vitro?. Journal of Controlled Release, 154 (3), (pp. 218-32) (15 p.).
van Rooy, I., Cakir-Tascioglu, S., Hennink, W.E., Storm, G., Schiffelers, R.M. & Mastrobattista, E. (2011). In vivo methods to study uptake of nanoparticles into the brain. Pharmaceutical Research, 28 (3), (pp. 456-71) (16 p.).
de Graaf, A.J., Boere, K.W.M., Kemmink, J., Fokkink, R.G., van Nostrum, C.F., Rijkers, D.T.S., van de Gucht, J., Wienk, H.L.J., Baldus, M., Mastrobattista, E., Vermonden, T. & Hennink, W.E. (2011). Looped structure of flowerlike Micelles revealed by 1H NMR relaxometry and light scattering. Langmuir, 27 (16), (pp. 9843-9848) (6 p.).
van Rooy, I., Wu, S.Y., Storm, G., Hennink, W.E., Dinter-Heidorn, H., Schiffelers, R.M. & Mastrobattista, E. (2011). Preparation and characterization of liposomal formulations of neurotensin-degrading enzyme inhibitors. International Journal of Pharmaceutics, 416 (2), (pp. 448-52) (5 p.).
  2010 - Scholarly publications
Amidi, M., Mastrobattista, E., Jiskoot, W. & Hennink, W.E. (2010). Chitosan-based delivery systems for protein therapeutics and antigens. Advanced Drug Delivery Reviews, 62 (1), (pp. 59-82) (24 p.).
van Hell, A.J., Klymchenko, A., Burgers, P.P., Moret, E.E., Jiskoot, W., Hennink, W.E., Crommelin, D.J.A. & Mastrobattista, E. (2010). Conformation and intermolecular interactions of SA2 peptides self-assembled into vesicles. Journal of Physical Chemistry B, 114 (34), (pp. 11046-52) (7 p.).
van Gaal, E.V.B., Spierenburg, G., Hennink, W.E., Crommelin, D.J.A. & Mastrobattista, E. (2010). Flow cytometry for rapid size determination and sorting of nucleic acid containing nanoparticles in biological fluids. Journal of Controlled Release, 141 (3), (pp. 328-38) (11 p.).
van Rooy, I., Cakir-Tascioglu, S., Couraud, P.O., Romero, I.A., Weksler, B., Storm, G., Hennink, W.E., Schiffelers, R.M. & Mastrobattista, E. (2010). Identification of peptide ligands for targeting to the blood-brain barrier. Pharmaceutical Research, 27 (4), (pp. 673-82) (10 p.).
van Gaal, E.V.B., Oosting, R.S., Hennink, W.E., Crommelin, D.J.A. & Mastrobattista, E. (2010). Junk DNA enhances pEI-based non-viral gene delivery. International Journal of Pharmaceutics, 390 (1), (pp. 76-83) (8 p.).
Amidi, M., de Raad, M., de Graauw, H., van Ditmarsch, D., Hennink, W.E., Crommelin, D.J.A. & Mastrobattista, E. (2010). Optimization and quantification of protein synthesis inside liposomes. Journal of Liposome Research, 20 (1), (pp. 73-83) (11 p.).
van Hell, A.J., Fretz, M.M., Crommelin, D.J.A., Hennink, W.E. & Mastrobattista, E. (2010). Peptide nanocarriers for intracellular delivery of photosensitizers. Journal of Controlled Release, 141 (3), (pp. 347-53) (7 p.).
Hagenaars, N., Mania, M.M., de Jong, P., Que, I., Nieuwland, R., Slutter, B., Glansbeek, H.L., Heldens, J., van den Bosch, H., Lowik, C., Kaijzel, E.L., Mastrobattista, E. & Jiskoot, W. (2010). Role of trimethylated chitosan (TMC) in nasal residence time, local distribution and toxicity of an intranasal influenza vaccine. Journal of Controlled Release, 144, (pp. 17-24) (8 p.).
  2009 - Scholarly publications
Wilschut, K.J., van der Aa, M., Oosting, R.S., Hennink, W.E., Koning, G.A., Crommelin, D.J.A. & Mastrobattista, E. (2009). Fluorescence in situ hybridization to monitor the intracellular location and accessibility of plasmid DNA delivered by cationic polymer-based gene carriers. European Journal of Pharmaceutics and Biopharmaceutics, 72 (2), (pp. 391-396) (6 p.). ISI:000267000800014.
de Graaf, A.J., Kooijman, M., Hennink, W.E. & Mastrobattista, E. (2009). Nonnatural Amino Acids for Site-Specific Protein Conjugation. Bioconjugate Chemistry, 20 (7), (pp. 1281-1295) (15 p.). ISI:000268137700001.
Hagenaars, N., Mastrobattista, E., Verheul, R.J., Mooren, I., Glansbeek, H.L., Heldens, J.G.M., van den Bosch, H. & Jiskoot, W. (2009). Physicochemical and Immunological Characterization of N,N,N-Trimethyl Chitosan-Coated Whole Inactivated Influenza Virus Vaccine for Intranasal Administration. Pharmaceutical Research, 26 (6), (pp. 1353-1364) (12 p.). ISI:000265834600007.
Hagenaars, N., Verheul, R.J., Mooren, I., de Jong, P.H.J.L.F, Mastrobattista, E., Glansbeek, H.L., Heldens, J.G., van den Bosch, H., Hennink, W.E. & Jiskoot, W. (2009). Relationship between structure and adjuvanticity of N,N,N-trimethyl chitosan (TMC) structural variants in a nasal influenza vaccine. Journal of Controlled Release, 140 (2), (pp. 126-33) (8 p.).
van Hell, A.J., Crommelin, D.J., Hennink, W.E. & Mastrobattista, E. (2009). Stabilization of peptide vesicles by introducing inter-peptide disulfide bonds. Pharmaceutical Research, 26 (9), (pp. 2186-93) (8 p.).
  2008 - Scholarly publications
Fens, M.H.A.M., Mastrobattista, E., de Graaff, A.M., Flesch, F.M., Ultee, A., Rasmussen, J., Molema, G., Storm, G. & Schiffelers, R.M. (2008). Angiogenic dndothelium shows lactadherin-dependent phagocytosis of aged erythrocytes and apoptotic cells. Blood, 111 (9), (pp. 4542-4550) (9 p.).
Hagenaars, N., Mastrobattista, E., Glansbeek, H.L., Helden, J., van den Bosch, H., Schijns, V., Betbeder, D., Vromans, H. & Jiskoot, W. (2008). Head-to-head comparison of four nonadjuvanted inactivated cell culture-derived influenza vaccines: Effect of composition, spatial organization and immunization route on the immunogenicity in a murine challenge model. Vaccine, 51, (pp. 6555-6563) (9 p.).
de Wolf, H.K., Johansson, N., Thong, A.T., Snel, C.J., Mastrobattista, E., Hennink, W.E. & Storm, G. (2008). Plasmid CpG depletion improves degree and duration of tumor gene expression after intravenous administration of polyplexes. Pharmaceutical Research, 25, (pp. 1654-1662) (9 p.).
  2007 - Scholarly publications
van der Aa, M.A.E.M., Huth, U.S., Häfele, S.Y., Schubert, R., Oosting, R.S., Mastrobattista, E., Hennink, W.E., Peschka-Süss, R., Koning, G.A. & Crommelin, D.J.A. (2007). Cellular uptake of cationic polymer-DNA complexes via caveolae plays a pivotal role in gene transfection in COS-7 cells. Pharmaceutical Research, 24, (pp. 1590-1598) (9 p.).
Mastrobattista, E., Hennink, W.E. & Schiffelers, R.M. (2007). Delivery of nucleic acids. Pharmaceutical Research, 24, (pp. 1561-1563) (3 p.).
van Hell, A.J., Costa, C.I.C.A., Flesch, F.M., Sutter, M., Jiskoot, W., Crommelin, D.J.A., Hennink, W.E. & Mastrobattista, E. (2007). Self-assembly of recombinant amphiphilic oligopeptides into vesicles. Biomacromolecules, 8, (pp. 2753-2761) (9 p.).
  2007 - Professional publications
Schiffelers, R.M. & Mastrobattista, E. (2007). Oligonucleotides. In D.J.A. Crommelin, R.D. Sindelar & B. Meibohm (Eds.), Pharmaceutical Biotechnology, An Introduction for Pharmacists and Pharmaceutical Scientists (pp. 211-223) (13 p.). New York/London: Informa Healthcare.
Jiskoot, W., Kersten, G.F.A. & Mastrobattista, E. (2007). Vaccines. In D.J.A. Crommelin, R.D. Sindelar & B. Meibohm (Eds.), Pharmaceutical Biotechnology, An Introduction for Pharmacists and Pharmaceutical Scientists (pp. 405-427) (23 p.). New York/London: Informa Healthcare.
  2006 - Scholarly publications
Mastrobattista, E., van der Aa, M.A.E.M., Hennink, W.E. & Crommelin, D.J.A. (2006). Artificial viruses: a nanotechnological approach to gene delivery. Nature Reviews Drug Discovery, 5, (pp. 115-121) (7 p.).
Miller, O.J., Bernath, K., Agresti, J.J., Amitai, G., Kelly, B.T., Mastrobattista, E., Taly, V., Magdassi, S., Tawfik, D.S. & Griffiths, A.D. (2006). Direct evolution by in vitro compartmentalization. Nature Methods, 3, (pp. 561-570) (10 p.).
van Gaal, E.V.B., Hennink, W.E., Crommelin, D.J.A. & Mastrobattista, E. (2006). Plasmid engineering for controlled and sustained gene expression for nonviral gene therapy. Pharmaceutical Research, 23, (pp. 1053-1074) (22 p.).
Koning, G.A., Schiffelers, R.M., Wauben, M.H.M., Kok, R.J., Mastrobattista, E., Molema, G., ten Hagen, T.L.M. & Storm, G. (2006). Targeting of angiogenic endothelial cells at sites of inflammation by dexamethasone phosphate-containing RGD peptide liposomes inhibits experimental arthritis. Arthritis and Rheumatism, 54, (pp. 1198-1208) (11 p.).
van der Aa, M.A.E.M., Mastrobattista, E., Oosting, R.S., Hennink, W.E., Koning, G.A. & Crommelin, D.J.A. (2006). The nuclear pore complex: the gateway to successful nonviral gene delivery. Pharmaceutical Research, 23 (3), (pp. 447-459) (13 p.).
  2005 - Scholarly publications
Mastrobattista, E., Taly, V., Chanudet, E., Treacy, P., Kelly, B.T. & Griffiths, A.D. (2005). High-throughput screening of enzyme libraries: in vitro evolution of a b-galactosidase by fluorescence-activated sorting of double emulsiom. Chemistry and Biology, 12, (pp. 1291-1300) (10 p.).
Mastrobattista, E., Bravo, S.A., van der Aa, M.A.E.M. & Crommelin, D.J.A. (2005). Nonviral gene delivery systems: from simple transfection agents to artifical viruses. Drug Discovery Today: Technologies, 2, (pp. 103-109) (7 p.).
Fretz, M.M., Mastrobattista, E., Koning, G.A., Jiskoot, W. & Storm, G. (2005). Strategies for cytosolic delivery of liposomal macromolecules. International Journal of Pharmaceutics, 298 (2), (pp. 305-309) (5 p.).
  2004 - Scholarly publications
Fretz, M.M., Koning, G.A., Mastrobattista, E., Jiskoot, W. & Storm, G. (2004). Ovcar-3 cells internalise TAT-peptide modified lipsomoes by endocytosis. Biochimica et Biophysica Acta - Biomembranes, 1665, (pp. 48-56) (9 p.).
  2003 - Scholarly publications
Crommelin, D.J.A., Storm, G., Jiskoot, W., Stenekes, R.J.H., Mastrobattista, E. & Hennink, W.E. (2003). Nanotechnological approaches for the delivery of macromolecules. Journal of Controlled Release, 87, (pp. 81-88) (8 p.).
  2002 - Scholarly publications
Mastrobattista, E., Koning, G.A., van Bloois, L., Filipe, A.C.S., Jiskoot, W. & Storm, G. (2002). Functional characterization of an endosome-disruptive peptide and its application in cytosolic delivery of immunoliposome-entrapped proteins. Journal of Biological Chemistry, 277, (pp. 27135-27143) (9 p.).
Metselaar, J.M., Mastrobattista, E. & Storm, G. (2002). Liposomes for intravenous drug targeting: design and applications. Mini-Reviews in Medicinal Chemistry, 2, (pp. 319-329) (11 p.).
Mastrobattista, E., Crommelin, D.J.A., Wilschut, J. & Storm, G. (2002). Targeted liposomes for delivery of protein-based drugs into the cytoplasm of tumor cells. Journal of Liposome Research, 12, (pp. 57-65) (9 p.).
  2001 - Scholarly publications
Storm, G., Mastrobattista, E., Verbaan, F.J., Crommelin, D.J.A. & Hennink, W.E. (2001). Design of methacrylate-based polyplexes for tumor targeting. Gene Therapy, 6, (pp. 143-148) (6 p.).
Mastrobattista, E., Kapel, R.H.G., Eggenhuisen, M.H., Roholl, P.J.M., Crommelin, D.J.A., Hennink, W.E. & Storm, G. (2001). Lipid-coated polyplexes for targeted gene delivery to ovarian carcinoma cells. Cancer Gene Therapy, 8, (pp. 405-413) (9 p.).
Mastrobattista, E., Schoen, P., Wilschut, J., Crommelin, D.J.A. & Storm, G. (2001). Targeting influenza vitrosomes to ovarian carcinoma cells. FEBS Letters, 509, (pp. 71-76) (6 p.).
  1999 - Scholarly publications
Mastrobattista, E., Storm, G., van Bloois, L., Reszka, R., Bloemen, P.G.M., Crommelin, D.J.A. & Henricks, P.A.J. (1999). Cellular uptake of liposomes targeted to intercellular adhesion molecule-1 (ICAM-1) on bronchial epithelial cells. Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 1419, (pp. 353-363) (11 p.).
Mastrobattista, E., Koning, G.A. & Storm, G. (1999). Immunoliposomes for the targeted deliverey of antitumor drugs. Advanced Drug Delivery Reviews, 40, (pp. 103-127) (25 p.).
^ top
Gegenereerd op 2017-11-19 08:09:52
Additional functions and activities

Board member of the Netherlands Society of Gene and Cell Therapy (honorary)

Gegenereerd op 2017-11-19 08:09:52
Full name
dr. E. Mastrobattista Contact details
David de Wiedgebouw

Universiteitsweg 99
Room 3.86
3584 CG  UTRECHT
The Netherlands


Phone number (direct) +31 6 22 736 567
Mobile phone +31 6 22 736 567
Gegenereerd op 2017-11-19 08:09:52
Last updated 22.05.2017