Dr. D.L. (Daniel) Hurdiss

Assistant Professor
Virology

Link to "Daniel L. Hurdiss" in Google Scholar

 

*=co-first author / ^=co-corresponding author / O=open access.

2023

 

MF Pronker, R Creutznacher, I Drulyte, RJG Hulswit, Z Li, FJM van Kuppeveld, J Snijder, Y Lang, BJ Bosch, GJ Boons, M Frank, RJ de Groot^, DL Hurdiss^. Sialoglycan binding triggers spike opening in a human coronavirus. bioRxiv. 

 

Thijssen V*, Hurdiss DL*, Debski-Antoniak OJ, Spence MA, Franck C, Norman A, Aggarwal A, Mokiem NJ, van Dongen DAA, Vermeir SW, Liu M, Li W, Chatziandreou M, Donselaar T, Du W, Drulyte I, Bosch BJ, Snijder J, Turville SG, Payne RJ, Jackson CJ, van Kuppeveld FJM^, Jongkees SAK^. A broad-spectrum macrocyclic peptide inhibitor of the SARS-CoV-2 spike protein. Proc Natl Acad Sci U S A. 2023 Jun 27;120(26):e2303292120. doi: 10.1073/pnas.2303292120. Epub 2023 Jun 20. PMID: 37339194; PMCID: PMC10293842.

 

Aloise C, Schipper JG, van Vliet A, Oymans J, Donselaar T, Hurdiss DL, de Groot RJ^, van Kuppeveld FJM^. SARS-CoV-2 nucleocapsid protein inhibits the PKR-mediated integrated stress response through RNA-binding domain N2b. PLoS Pathog. 2023 Aug 22;19(8):e1011582. doi: 10.1371/journal.ppat.1011582. PMID: 37607209; PMCID: PMC10473545.

 

W Du, R Janssens, AZ Mykytyn, W Li, D Drabek, R van Haperen, M Chatziandreou, M Rissmann, J van der Lee, M van Dortmondt, I Serna Martin, FJM van Kuppeveld, DL Hurdiss, BL Haagmans, F Grosveld, BJ Bosch. Avidity engineering of human heavy-chain-only antibodies mitigates neutralization resistance of SARS-CoV-2 variants. Frontiers in Immunology. 

 

G Swinscoe, EL Prescott, DL Hurdiss, EL Morgan, SJ Dobson, T Edwards, R Foster, M Welberry Smith, A Macdonald. The virus-encoded ion channel activity of the agnoprotein is required for BK Polyomavirus release from infected kidney cells. bioRxiv. 

 

2022

Rothenberger, S*, Hurdiss, DL*, Walser, M* et al. The trispecific DARPin ensovibep inhibits diverse SARS-CoV-2 variants. Nature Biotechnology (2022). https://doi.org/10.1038/s41587-022-01382-3. O

 

Chunyan Wang, Emma L. Hesketh, Tatiana M. Shamorkina, Wentao Li, Peter J. Franken, Dubravka Drabek, Rien van Haperen, Sarah Townend, Frank J. M. van Kuppeveld, Frank Grosveld, Neil A. Ranson, Joost Snijder, Raoul J. de Groot, Daniel L. Hurdiss^ & Berend-Jan Bosch^. "Antigenic structure of the human coronavirus OC43 spike reveals exposed and occluded neutralizing epitopes." Nature Communications. DOI: 0.1038/s41467-022-30658-0. O

 

Du W, Hurdiss DL, Drabek D, Mykytyn AZ, Kaiser FK, González-Hernández M, Muñoz-Santos D, Lamers MM, van Haperen R, Li W, Drulyte I, Wang C, Sola I, Armando F, Beythien G, Ciurkiewicz M, Baumgärtner W, Guilfoyle K, Smits T, van der Lee J, van Kuppeveld FJM, van Amerongen G, Haagmans BL, Enjuanes L, Osterhaus ADME, Grosveld F, Bosch BJ. "An ACE2-blocking antibody confers broad neutralization and protection against Omicron and other SARS-CoV-2 variants of concern." Science Immunology. DOI: 10.1126/sciimmunol.abp9312. O

 

Daniel L. Hurdiss*^, Priscila El Kazzi*, Lisa Bauer*, Nicolas Papageorgiou, François P. Ferron, Tim Donselaar, Arno L. W. van Vliet, Bruno Canard, Etienne Decroly, Andrea Brancale, Tzviya Zeev-Ben-Mordehai, Friedrich Förster, Frank J. M. van Kuppeveld^, and Bruno Coutard^. 2021. “Fluoxetine targets an allosteric site in the enterovirus 2C AAA+ ATPase and stabilizes a ring-shaped hexameric complex." Science Advances. DOI: 10.1126/sciadv.abj7615. O

 

2021

 

Juliette Fedry*, Daniel L. Hurdiss*, Chunyan Wang*, Wentao Li*, Gonzalo Obal, Ieva Drulyte,Wenjuan Du, Stuart C. Howes, Frank J. M. van Kuppeveld, Friedrich Förster, and Berend-Jan Bosch. 2021. “Structural Insights into the Cross-Neutralization of SARS-CoV and SARS-CoV-2 by the Human Monoclonal Antibody 47D11.” Science Advances. doi: 10.1126/sciadv.abf5632. O

 

Johansson, E.; Caraballo, R.; Hurdiss, D.L.; Mistry, N.; Andersson, C.D.; Thompson, R.F.; Ranson, N.A.; Zocher, G.; Stehle, T.; Arnberg, N.; Elofsson, M. Exploring the Effect of Structure-Based Scaffold Hopping on the Inhibition of Coxsackievirus A24v Transduction by Pentavalent N-Acetylneuraminic Acid Conjugates. Int. J. Mol. Sci. 2021, 22, 8418. https://doi.org/10.3390/ijms22168418. 

 

C Wang, R van Haperen, J Gutiérrez-Álvarez, W Li, Nisreen MA Okba, I Albulescu, I Widjaja, B van Dieren, R Fernandez-Delgado, I Sola, DL Hurdiss, O Daramola, F Grosveld, FJM van Kuppeveld, BL Haagmans, L Enjuanes, D Drabek & BJ Bosch. A conserved immunogenic and vulnerable site on the coronavirus spike protein delineated by cross-reactive monoclonal antibodies. Nature Communications. March 2021. O

 

2020

 

Daniel L. Hurdiss^, Ieva Drulyte, Yifei Lang, Tatiana M. Shamorkina, Matti F. Pronker, Frank J. M. van Kuppeveld, Joost Snijder, and Raoul J. de Groot^. 2020. “Cryo-EM Structure of Coronavirus-HKU1 Haemagglutinin Esterase Reveals Architectural Changes Arising from Prolonged Circulation in Humans.” Nature Communications 11(1). doi: 10.1038/s41467-020-18440-6. O

 

Lisa Bauer, Roberto Manganaro, Birgit Zonsics, Daniel L. Hurdiss, Marleen Zwaagstra, Tim Donselaar, Naemi G. E. Welter, Regina G. D. M. Van Kleef, Moira Lorenzo Lopez, Federica Bevilacqua, Thamidur Raman, Salvatore Ferla, Marcella Bassetto, Johan Neyts, Jeroen R. P. M. Strating, Remco H. S. Westerink, Andrea Brancale, and Frank J. M. Van Kuppeveld. 2020. “Rational Design of Highly Potent Broad spectrum Enterovirus Inhibitors Targeting the Nonstructural Protein 2C.” PLoS Biology 18(11). doi: 10.1371/journal.pbio.3000904. O

 

Marcel Walser*, Sylvia Rothenberger*, Daniel L. Hurdiss*, Anja Schlegel, Valérie Calabro, Simon Fontaine, Denis Villemagne, Maria Paladino, Tanja Hospodarsch, Alexandra Neculcea, Andreas Cornelius, Patricia Schildknecht, Mirela Matzner, Martin Hänggi, Marco Franchini, Yvonne Kaufmann, Iris Schlegel, Chloe Iss, Thamar Loser, Susanne Mangold, Christel Herzog, Dieter Schiegg, Christian Reichen, Filip Radom, Andreas Bosshart, Andreas Lehmann, Micha A. Haeuptle, Alexander Zürcher, Toni Vagt, Gabriel Sigrist, Marcel Straumann, Karl Proba, Niina Veitonmäki, Keith M. Dawson, Christof Zitt, Jennifer Mayor, Sarah Ryter, Heyrhyoung Lyoo, Chunyan Wang, Wentao Li, Ieva Drulyte, H. Kaspar Binz, Leon de Waal, Koert J. Stittelaar, Seth Lewis, Daniel Steiner, Frank J. M. van Kuppeveld, Olivier Engler, Berend Jan Bosch, Michael T. Stumpp, and Patrick Amstutz. 2020. “Highly Potent Anti-SARS-CoV-2 Multi-DARPin Therapeutic Candidates.” BioRxiv. doi: 10.1101/2020.08.25.256339. O

 

E Johansson, R Caraballo, N Mistry, G Zocher, W Qian, D Andersson, DL Hurdiss, N Chandra, RF Thompson, L Frängsmyr, T Stehle, N Arnberg & M Elofsson. Pentavalent Sialic Acid Conjugates Block Coxsackievirus A24 Variant and Human Adenovirus Type 37–Viruses That Cause Highly Contagious Eye Infections. ACS Chemical Biology. August 2020.

 

R Manganaro*, B Zonsics*, L Bauer*, M Lorenzo, T Donselaar, M Zwaagstra, F Saporito, S Ferla, JRPM Strating, B Coutard, DL Hurdiss, FJM van kuppeveld and A Brancale. Synthesis and antiviral effect of novel fluoxetine analogues as enterovirus 2C inhibitors. Antiviral Research. March 2020.

 

Joseph S. Snowden, Daniel L. Hurdiss, Oluwapelumi O. Adeyemi, Neil A. Ranson, Morgan R. Herod, and Nicola J. Stonehouse. 2020. “Dynamics in the Murine Norovirus Capsid Revealed by High-Resolution Cryo-EM.” PLoS Biology 18(3). doi: 10.1371/journal.pbio.3000649. O

 

2019

 

J Baggen, HJ Thibaut, DL Hurdiss, M Wahedi, CD Marceau, ALW van Vliet, JE Carette and FJM van Kuppeveld. Identification of the Cell-Surface Protease ADAM9 as an Entry Factor for Encephalomyocarditis Virus, mBio. August 2019.

 

J Marsian, DL Hurdiss, NA Ranson, A Ritala, RK Paley, IC Cejas and GP Lomonossoff. Plant-made Nervous Necrosis Virus-like particles protect fish against disease, Frontiers in Plant Science. July 2019. DOI=10.3389/fpls.2019.00880.  O

 

JF Ross, GC Wildsmith, M Johnson, DL Hurdiss, K Hollingsworth, RF Thompson, M Mosayebi, CH Trinh, E Paci, AR Pearson, ME Webb and WB Turnbull. Directed assembly of homo-pentameric cholera toxin B-subunit proteins into higher-order structures using coiled-coil appendages, JACS, March 2019.

 

2018

 

Daniel L. Hurdiss, Martin Frank, Joseph S. Snowden, Andrew Macdonald, and Neil A. Ranson. 2018. “The Structure of an Infectious Human Polyomavirus and Its Interactions with Cellular Receptors.” Structure 26(6). doi: 10.1016/j.str.2018.03.019. O

 

Drulyte I, Johnson RM, Hesketh EL, Hurdiss DL, Scarff CA, Porav SA, Ranson NA, Muench SP and Thompson RF. Approaches to altering particle distributions in cryo-electron microscopy sample preparation, Acta Cryst D, June 2018. O

 

Panou MM*, Prescott EL*, Hurdiss DL, Swinscoe G, Hollinshead M, Caller LG, Morgan EL, Carlisle L, Müller M, Antoni M, Kealy D, Ranson NA, Crump CM, Macdonald A. Agnoprotein Is an Essential Egress Factor during BK Polyomavirus Infection. Int J Mol Sci. 2018 Mar 19;19(3):902. doi: 10.3390/ijms19030902. PMID: 29562663; PMCID: PMC5877763. O

 

Shaun Rawson*, Claudine Bisson*, Daniel L. Hurdiss*, Asif Fazal, Martin J. McPhillie, Svetlana E. Sedelnikova, Patrick J. Baker, David W. Rice, and Stephen P. Muench. 2018. “Elucidating the Structural Basis for Differing Enzyme Inhibitor Potency by Cryo-EM.” Proceedings of the National Academy of Sciences of the United States of America 115(8). doi: 10.1073/pnas.1708839115. O

 

Jim Baggen*, Daniel L. Hurdiss*, Georg Zocher, Nitesh Mistry, Richard W. Roberts, Jasper J. Slager, Hongbo Guo, Arno L. W. Van Vliet, Maryam Wahedi, Kimberley Benschop, Erwin Duizer, Cornelis A. M. De Haan, Erik De Vries, José M. Casasnovas, Raoul J. De Groot, Niklas Arnberg, Thilo Stehle, Neil A. Ranson, Hendrik Jan Thibaut, and Frank J. M. Van Kuppeveld. 2018. “Role of Enhanced Receptor Engagement in the Evolution of a Pandemic Acute Hemorrhagic Conjunctivitis Virus.” Proceedings of the National Academy of Sciences of the United States of America 115(2). doi: 10.1073/pnas.1713284115. O

 

2016

 

Daniel L. Hurdiss, Ethan L. Morgan, Rebecca F. Thompson, Emma L. Prescott, Margarita-Maria Panou, Andrew Macdonald and Neil A. Ranson. New structural insights into the genome and minor capsid proteins of BK polyomavirus using cryo-electron microscopy, Structure, April 2016. O

·       Front cover (April 2016 Issue).

·       Preview article: C Buck. Exposing the Molecular Machinery of BK Polyomavirus, Structure 24 (4), 495, April 2016.

 

 

 

Publications

2022

Scholarly publications

Wang, C., Hesketh, E. L., Shamorkina, T. M., Li, W., Franken, P. J., Drabek, D., van Haperen, R., Townend, S., van Kuppeveld, F. J. M., Grosveld, F., Ranson, N. A., Snijder, J., de Groot, R. J., Hurdiss, D. L., & Bosch, B-J. (2022). Antigenic structure of the human coronavirus OC43 spike reveals exposed and occluded neutralizing epitopes. Nature Communications, 13(1), 1-15. [2921]. https://doi.org/10.1038/s41467-022-30658-0
Du, W., Hurdiss, D. L., Drabek, D., Mykytyn, A. Z., Kaiser, F. K., González-Hernández, M., Muñoz-Santos, D., Lamers, M. M., van Haperen, R., Li, W., Drulyte, I., Wang, C., Sola, I., Armando, F., Beythien, G., Ciurkiewicz, M., Baumgärtner, W., Guilfoyle, K., Smits, T., ... Bosch, B-J. (2022). An ACE2-blocking antibody confers broad neutralization and protection against Omicron and other SARS-CoV-2 variants of concern. Science immunology, [eabp9312]. https://doi.org/10.1126/sciimmunol.abp9312
Hurdiss, D. L., El Kazzi, P., Bauer, L., Papageorgiou, N., Ferron, F. P., Donselaar, T., Van Vliet, A. L. W., Shamorkina, T. M., Snijder, J., Canard, B., Decroly, E., Brancale, A., Zeev-Ben-Mordehai, T., Förster, F., Van Kuppeveld, F. J. M., & Coutard, B. (2022). Fluoxetine targets an allosteric site in the enterovirus 2C AAA+ ATPase and stabilizes a ring-shaped hexameric complex. Science advances, 8(1), [abj7615]. https://doi.org/10.1126/sciadv.abj7615

2021

Scholarly publications

Fedry, J., Hurdiss, D. L., Wang, C., Li, W., Obal, G., Drulyte, I., Du, W., Howes, S. C., van Kuppeveld, F. J. M., Förster, F., & Bosch, B-J. (2021). Structural insights into the cross-neutralization of SARS-CoV and SARS-CoV-2 by the human monoclonal antibody 47D11. Science advances, 7(23), 1-11. [eabf5632]. https://doi.org/10.1126/sciadv.abf5632
Wang, C., van Haperen, R., Gutiérrez-Álvarez, J., Li, W., Okba, N. M. A., Albulescu, I., Widjaja, I., van Dieren, B., Fernandez-Delgado, R., Sola, I., Hurdiss, D. L., Daramola, O., Grosveld, F., van Kuppeveld, F. J. M., Haagmans, B. L., Enjuanes, L., Drabek, D., & Bosch, B-J. (2021). A conserved immunogenic and vulnerable site on the coronavirus spike protein delineated by cross-reactive monoclonal antibodies. Nature Communications, 12(1), 1-15. [1715]. https://doi.org/10.1038/s41467-021-21968-w

2020

Scholarly publications

Snowden, J. S., Chiu, W., Hurdiss, D. L., Adeyemi, O. O., Ranson, N. A., Herod, M. R., & Stonehouse, N. J. (2020). Dynamics in the murine norovirus capsid revealed by high-resolution cryo-EM. PLoS Biology, 18(3), [e3000649]. https://doi.org/10.1371/journal.pbio.3000649
Bauer, L., Manganaro, R., Zonsics, B., Hurdiss, D. L., Zwaagstra, M., Donselaar, T., Welter, N. G. E., van Kleef, R. G. D. M., Lopez, M. L., Bevilacqua, F., Raman, T., Ferla, S., Bassetto, M., Neyts, J., Strating, J. R. P. M., Westerink, R. H. S., Brancale, A., & van Kuppeveld, F. J. M. (2020). Rational design of highly potent broad-spectrum enterovirus inhibitors targeting the nonstructural protein 2C. PLoS Biology, 18(11), [e3000904]. https://doi.org/10.1371/journal.pbio.3000904
Hurdiss, D. L., Drulyte, I., Lang, Y., Shamorkina, T. M., Pronker, M. F., van Kuppeveld, F. J. M., Snijder, J., & de Groot, R. J. (2020). Cryo-EM structure of coronavirus-HKU1 haemagglutinin esterase reveals architectural changes arising from prolonged circulation in humans. Nature Communications, 11(1), 1-10. [4646]. https://doi.org/10.1038/s41467-020-18440-6
Manganaro, R., Zonsics, B., Bauer, L., Lorenzo Lopez, M., Donselaar, T., Zwaagstra, M., Saporito, F., Ferla, S., Strating, J. R. P. M., Coutard, B., Hurdiss, D. L., van Kuppeveld, F. J. M., & Brancale, A. (2020). Synthesis and antiviral effect of novel fluoxetine analogues as enterovirus 2C inhibitors. Antiviral Research, [104781]. https://doi.org/10.1016/j.antiviral.2020.104781

2019

Scholarly publications

Baggen, J., Thibaut, H. J., Hurdiss, D. L., Wahedi, M., Marceau, C. D., van Vliet, A. L. W., Carette, J. E., & van Kuppeveld, F. J. M. (2019). Identification of the Cell-Surface Protease ADAM9 as an Entry Factor for Encephalomyocarditis Virus. mBio, 10(4), [e01780-19]. https://doi.org/10.1128/mBio.01780-19

2018

Scholarly publications

Rawson, S., Bisson, C., Hurdiss, D. L., Fazal, A., McPhillie, M. J., Sedelnikova, S. E., Baker, P. J., Rice, D. W., & Muench, S. P. (2018). Elucidating the structural basis for differing enzyme inhibitor potency by cryo-EM. Proceedings of the National Academy of Sciences, 115(8), 1795-1800. https://doi.org/10.1073/pnas.1708839115
Baggen, J., Hurdiss, D. L., Zocher, G., Mistry, N., Roberts, R. W., Slager, J. J., Guo, H., van Vliet, A. L. W., Wahedi, M., Benschop, K., Duizer, E., de Haan, C. A. M., de Vries, E., Casasnovas, J. M., de Groot, R. J., Arnberg, N., Stehle, T., Ranson, N. A., Thibaut, H. J., & van Kuppeveld, F. J. M. (2018). Role of enhanced receptor engagement in the evolution of a pandemic acute hemorrhagic conjunctivitis virus. Proceedings of the National Academy of Sciences of the United States of America, 115(2), 397-402. https://doi.org/10.1073/pnas.1713284115

2016

Scholarly publications

Hurdiss, D. L., Morgan, E. L., Thompson, R. F., Prescott, E. L., Panou, M. M., Macdonald, A., & Ranson, N. A. (2016). New Structural Insights into the Genome and Minor Capsid Proteins of BK Polyomavirus using Cryo-Electron Microscopy. Structure, 24(4), 528-536. https://doi.org/10.1016/j.str.2016.02.008