My group performs fundamental research on viruses, with the ultimate goal of translating this knowledge into new approaches to prevent or treat infections. Specifically, we aim to determine the three-dimensional structures of viral proteins and understand how these relate to their functions. To achieve this, we use cryo-electron microscopy in combination with biochemical and molecular virology techniques.

By gaining mechanistic insights into how viruses invade, hijack, and escape host cells, we hope to identify new targets for antiviral intervention using small molecules or biologics.

Our current research interests fall into three main areas:

1) Virus structure, receptors, and entry mechanisms
2) Virus replication and assembly
3) Development of antiviral drugs

Through our work in these areas, we aim to advance understanding of viral pathogenesis and contribute to the development of effective antiviral therapies.

Research Highlights