Prof. dr. A. (Tassos) Perrakis

Hugo R. Kruytgebouw
Padualaan 8
3584 CH Utrecht

Prof. dr. A. (Tassos) Perrakis

Professor
Structural Biochemistry
a.perrakis@uu.nl

Publications

2022

Scholarly publications

Pataskar, A., Champagne, J., Nagel, R., Kenski, J., Laos, M., Michaux, J., Pak, H. S., Bleijerveld, O. B., Mordente, K., Navarro, J. M., Blommaert, N., Nielsen, M. M., Lovecchio, D., Stone, E., Georgiou, G., de Gooijer, M. C., van Tellingen, O., Altelaar, M., Joosten, R. P., ... Agami, R. (2022). Tryptophan depletion results in tryptophan-to-phenylalanine substitutants. Nature, 603(7902), 721-727. https://doi.org/10.1038/s41586-022-04499-2

2019

Scholarly publications

Morris, C., Andreetto, P., Banci, L., Bonvin, A. M. J. J., Chojnowski, G., Cano, L. D., Carazo, J. M., Conesa, P., Daenke, S., Damaskos, G., Giachetti, A., Haley, N. E. C., Hekkelman, M. L., Heuser, P., Joosten, R. P., Kouřil, D., Křenek, A., Kulhánek, T., Lamzin, V. S., ... Winn, M. (2019). West-Life: A Virtual Research Environment for structural biology. Journal of Structural Biology: X, 1, [100006]. https://doi.org/10.1016/j.yjsbx.2019.100006
Adamopoulos, A., Landskron, L., Heidebrecht, T., Tsakou, F., Bleijerveld, O. B., Altelaar, M., Nieuwenhuis, J., Celie, P. H. N., Brummelkamp, T. R., & Perrakis, A. (2019). Crystal structure of the tubulin tyrosine carboxypeptidase complex VASH1–SVBP. Nature Structural and Molecular Biology, 26(7), 567-570. https://doi.org/10.1038/s41594-019-0254-6

2018

Scholarly publications

van Veen, M., Mans, L. A., Matas-Rico, E., van Pelt, J., Perrakis, T., Moolenaar, W. H., & Haramis, A. P. G. (2018). Glycerophosphodiesterase GDE2/GDPD5 affects pancreas differentiation in zebrafish. International Journal of Biochemistry and Cell Biology, 94, 71-78. https://doi.org/10.1016/j.biocel.2017.11.015

2013

Scholarly publications

Houben, A. J. S., van Wijk, X. M. R., van Meeteren, L. A., van Zeijl, L., van de Westerlo, E. M. A., Hausmann, J., Fish, A., Perrakis, A., van Kuppevelt, T. H., & Moolenaar, W. H. (2013). The Polybasic Insertion in Autotaxin alpha Confers Specific Binding to Heparin and Cell Surface Heparan Sulfate Proteoglycans. Journal of Biological Chemistry. https://doi.org/10.1074/jbc.M112.358416

2011

Scholarly publications

Hausmann, J., Kamtekar, S., Christodoulou, E., Day, J. E., Wu, T., Fulkerson, Z., Albers, H., van Meeteren, L. A., Houben, A. J. S., van Zeijl, L., Jansen, S., Andries, M., Hall, T., Pegg, L. E., Benson, T. E., Kasiem, M., Harlos, K., Kooi, C. W. V., Smyth, S. S., ... Perrakis, A. (2011). Structural basis of substrate discrimination and integrin binding by autotaxin. Nature Structural and Molecular Biology, 18, 198–204. https://doi.org/10.1038/nsmb.1980

2010

Scholarly publications

Hausmann, J., Christodoulou, E., Kasiem, M., De Marco, V., van Meeteren, L. A., Moolenaar, W. H., Axford, D., Owen, R. L., Evans, G., & Perrakis, A. (2010). Mammalian cell expression, purification, crystallization and microcrystal data collection of autotaxin/ENPP2, a secreted mammalian glycoprotein. Acta Crystallographica Section F: Structural Biology and Crystallization Communications. https://doi.org/10.1107/s1744309110032938