Publications
2024
Scholarly publications
Stork, E. M., van Rijswijck, D. M. H., van Schie, K. A., Hoek, M., Kissel, T., Scherer, H. U., Huizinga, T. W. J., Heck, A. J. R., Toes, R. E. M., & Bondt, A. (2024). Antigen-specific Fab profiling achieves molecular-resolution analysis of human autoantibody repertoires in rheumatoid arthritis. Nature Communications, 15(1), Article 3114. https://doi.org/10.1038/s41467-024-47337-x
https://dspace.library.uu.nl/bitstream/handle/1874/438266/s41467-024-47337-x.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/438266/s41467-024-47337-x.pdf?sequence=1
van Rijswijck, D. M. H., Bondt, A., de Kat, N., Lood, R., & Heck, A. J. R. (2024). Direct Comparison of the Hinge-Cleaving Proteases IgdE and BdpK for LC-MS-Based IgG1 Clonal Profiling. Analytical Chemistry, 96(1), 23-27. https://doi.org/10.1021/acs.analchem.3c03712
https://dspace.library.uu.nl/bitstream/handle/1874/435150/van-rijswijck-et-al-2023-direct-comparison-of-the-hinge-cleaving-proteases-igde-and-bdpk-for-lc-ms-based-igg1-clonal.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/435150/van-rijswijck-et-al-2023-direct-comparison-of-the-hinge-cleaving-proteases-igde-and-bdpk-for-lc-ms-based-igg1-clonal.pdf?sequence=1
Bondt, A., Hoek, M., Dingess, K., Tamara, S., de Graaf, B., Peng, W., den Boer, M. A., Damen, M., Zwart, C., Barendregt, A., van Rijswijck, D. M. H., Schulte, D., Grobben, M., Tejjani, K., van Rijswijk, J., Völlmy, F., Snijder, J., Fortini, F., Papi, A., ... Heck, A. J. R. (2024). Into the dark serum proteome: personalized features of IgG1 and IgA1 repertoires in severe COVID-19 patients. Molecular and Cellular Proteomics, 23(1), 100690. Article 100690. https://doi.org/10.1016/j.mcpro.2023.100690
https://dspace.library.uu.nl/bitstream/handle/1874/434962/PIIS1535947623002013.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/434962/PIIS1535947623002013.pdf?sequence=1
2023
Scholarly publications
de Graaf, S. C., Bondt, A., van Rijswijck, D. M. H., Juncker, H. G., Mulleners, S. J., Damen, M. J. A., Hoek, M., van Keulen, B. J., van Goudoever, J. B., Heck, A. J. R., & Dingess, K. A. (2023). A case series exploring the human milk polyclonal IgA1 response to repeated SARS-CoV-2 vaccinations by LC-MS based fab profiling. Frontiers in Nutrition, 10, 1305086. https://doi.org/10.3389/fnut.2023.1305086
Oskam, N., den Boer, M. A., Lukassen, M. V., Ooijevaar-De Heer, P., Veth, T. S., van Mierlo, G., Lai, S. H., Derksen, N. I. L., Yin, V., Streutker, M., Franc, V., Šiborová, M., Damen, M. J. A., Kos, D., Barendregt, A., Bondt, A., van Goudoever, J. B., de Haas, C. J. C., Aerts, P. C., ... Heck, A. J. R. (2023). CD5L is a canonical component of circulatory IgM. Proceedings of the National Academy of Sciences of the United States of America, 120(50), 1-7. Article e2311265120. https://doi.org/10.1073/pnas.2311265120
https://dspace.library.uu.nl/bitstream/handle/1874/435151/oskam-et-al-2023-cd5l-is-a-canonical-component-of-circulatory-igm.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/435151/oskam-et-al-2023-cd5l-is-a-canonical-component-of-circulatory-igm.pdf?sequence=1
Peng, W., den Boer, M. A., Tamara, S., Mokiem, N. J., van der Lans, S. P. A., Bondt, A., Schulte, D., Haas, P.-J., Minnema, M. C., Rooijakkers, S. H. M., van Zuilen, A. D., Heck, A. J. R., & Snijder, J. (2023). Direct Mass Spectrometry-Based Detection and Antibody Sequencing of Monoclonal Gammopathy of Undetermined Significance from Patient Serum: A Case Study. Journal of Proteome Research, 22(9), 3022-3028. https://doi.org/10.1021/acs.jproteome.3c00330
https://dspace.library.uu.nl/bitstream/handle/1874/434237/peng-et-al-2023-direct-mass-spectrometry-based-detection-and-antibody-sequencing-of-monoclonal-gammopathy-of.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/434237/peng-et-al-2023-direct-mass-spectrometry-based-detection-and-antibody-sequencing-of-monoclonal-gammopathy-of.pdf?sequence=1
Volkov, M., Brinkhaus, M., van Schie, K. A., Bondt, A., Kissel, T., van der Kooi, E. J., Bentlage, A. E. H., Koeleman, C. A. M., de Taeye, S. W., Derksen, N. I., Dolhain, R. J. E. M., Braig-Scherer, U., Huizinga, T. W. J., Wuhrer, M., Toes, R. E. M., Vidarsson, G., & van der Woude, D. (2023). IgG Fab Glycans Hinder FcRn-Mediated Placental Transport. Journal of Immunology, 210(2), 158-167. https://doi.org/10.4049/jimmunol.2200438
Dingess, K. A., Hoek, M., van Rijswijk, D. M. H., Tamara, S., den Boer, M. A., Veth, T., Damen, M. J. A., Barendregt, A., Romijn, M., Juncker, H. G., van Keulen, B. J., Vidarsson, G., van Goudoever, J. B., Bondt, A., & Heck, A. J. R. (2023). Identification of common and distinct origins of human serum and breastmilk IgA1 by mass spectrometry-based clonal profiling. Cellular and Molecular Immunology, 20(1), 26-37. https://doi.org/10.1038/s41423-022-00954-2
2022
Scholarly publications
van Rijswijck, D. M. H., Bondt, A., Hoek, M., van der Straten, K., Caniels, T. G., Poniman, M., Eggink, D., Reusken, C., de Bree, G. J., Sanders, R. W., van Gils, M. J., & Heck, A. J. R. (2022). Discriminating cross-reactivity in polyclonal IgG1 responses against SARS-CoV-2 variants of concern. Nature Communications, 13(1), Article 6103. https://doi.org/10.1038/s41467-022-33899-1
2021
Scholarly publications
Bondt, A., Dingess, K. A., Hoek, M., van Rijswijck, D. M. H., & Heck, A. J. R. (2021). A Direct MS-Based Approach to Profile Human Milk Secretory Immunoglobulin A (IgA1) Reveals Donor-Specific Clonal Repertoires With High Longitudinal Stability. Frontiers in Immunology, 12, 1-11. Article 789748. https://doi.org/10.3389/fimmu.2021.789748
Greisch, J.-F., den Boer, M. A., Lai, S.-H., Gallagher, K., Bondt, A., Commandeur, J., & Heck, A. J. R. (2021). Extending Native Top-Down Electron Capture Dissociation to MDa Immunoglobulin Complexes Provides Useful Sequence Tags Covering Their Critical Variable Complementarity-Determining Regions. Analytical Chemistry, 93(48), 16068-16075. https://doi.org/10.1021/acs.analchem.1c03740
Bondt, A., Hoek, M., Tamara, S., de Graaf, B., Peng, W., Schulte, D., van Rijswijck, D. M. H., den Boer, M. A., Greisch, J.-F., Varkila, M. R. J., Snijder, J., Cremer, O. L., Bonten, M. J. M., & Heck, A. J. R. (2021). Human plasma IgG1 repertoires are simple, unique, and dynamic. Cell Systems, 12(12), 1131-1143.e5. https://doi.org/10.1016/j.cels.2021.08.008
van Keulen, B. J., Romijn, M., Bondt, A., Dingess, K. A., Kontopodi, E., van der Straten, K., den Boer, M. A., Burger, J. A., Poniman, M., Bosch, B. J., Brouwer, P. J. M., de Groot, C. J. M., Hoek, M., Li, W., Pajkrt, D., Sanders, R. W., Schoonderwoerd, A., Tamara, S., Timmermans, R. A. H., ... van Goudoever, J. B. (2021). Human Milk from Previously COVID-19-Infected Mothers: The Effect of Pasteurization on Specific Antibodies and Neutralization Capacity. Nutrients, 13(5), 1-14. Article 1645. https://doi.org/10.3390/nu13051645
Greisch, J.-F., den Boer, M. A., Beurskens, F., Schuurman, J., Tamara, S., Bondt, A., & Heck, A. J. R. (2021). Generating Informative Sequence Tags from Antigen-Binding Regions of Heavily Glycosylated IgA1 Antibodies by Native Top-Down Electron Capture Dissociation. Journal of the American Society for Mass Spectrometry, 32(6), 1326-1335. https://doi.org/10.1021/jasms.0c00461
2020
Scholarly publications
den Boer, M. A., Greisch, J.-F., Tamara, S., Bondt, A., & Heck, A. J. R. (2020). Selectivity over coverage in de novo sequencing of IgGs. Chemical Science, 11(43), 11886-11896. https://doi.org/10.1039/d0sc03438j
Momčilović, A., de Haan, N., Hipgrave Ederveen, A. L., Bondt, A., Koeleman, C. A. M., Falck, D., de Neef, L. A., Mesker, W. E., Tollenaar, R., de Ru, A., van Veelen, P., Wuhrer, M., & Dotz, V. (2020). Simultaneous Immunoglobulin A and G Glycopeptide Profiling for High-Throughput Applications. Analytical Chemistry, 92(6), 4518-4526. https://doi.org/10.1021/acs.analchem.9b05722
2018
Scholarly publications
Reiding, K. R., Bondt, A., Franc, V., & Heck, A. J. R. (2018). The benefits of hybrid fragmentation methods for glycoproteomics. TrAC - Trends in Analytical Chemistry, 108, 260-268. https://doi.org/10.1016/j.trac.2018.09.007
2014
Scholarly publications
Pereboom, T. C., Bondt, A., Pallaki, P., Klasson, T. D., Goos, Y. J., Essers, P. B., Groot Koerkamp, M. J. A., Gazda, H. T., Holstege, F. C. P., & Costa, L. D. (2014). Translation of branched-chain aminotransferase-1 transcripts is impaired in cells haploinsufficient for ribosomal protein genes. Experimental Hematology, 42, 394-403. https://doi.org/10.1016/j.exphem.2013.12.010