Dr. S. (Silvia) Mihaila

David de Wiedgebouw
Universiteitsweg 99
3584 CG Utrecht

Dr. S. (Silvia) Mihaila

Universitair docent
Pharmacology
s.mihaila@uu.nl

Publicaties

2024

Wetenschappelijke publicaties

Orge, I. D., Nogueira Pinto, H., Silva, M. A., Bidarra, S. J., Ferreira, S. A., Calejo, I., Masereeuw, R., Mihăilă, S. M., & Barrias, C. C. (2024). Vascular units as advanced living materials for bottom-up engineering of perfusable 3D microvascular networks. Bioactive Materials, 38, 499-511. https://doi.org/10.1016/j.bioactmat.2024.05.021
Janssen, R., Benito‐Zarza, L., Cleijpool, P., Valverde, M. G., Mihăilă, S. M., Bastiaan‐Net, S., Garssen, J., Willemsen, L. E. M., & Masereeuw, R. (2024). Biofabrication Directions in Recapitulating the Immune System‐on‐a‐Chip. Advanced healthcare materials, Article 2304569. Advance online publication. https://doi.org/10.1002/adhm.202304569

2023

Wetenschappelijke publicaties

Faria, J., Calcat-i-Cervera, S., Skovronova, R., Broeksma, B. C., Berends, A. J., Zaal, E. A., Bussolati, B., O’Brien, T., Mihăilă, S. M., & Masereeuw, R. (2023). Mesenchymal stromal cells secretome restores bioenergetic and redox homeostasis in human proximal tubule cells after ischemic injury. Stem cell research & therapy, 14(1), 1-19. Article 353. https://doi.org/10.1186/s13287-023-03563-6
https://dspace.library.uu.nl/bitstream/handle/1874/434991/s13287-023-03563-6.pdf?sequence=1
Ahmed, S., Vries, J. C. D., Lu, J., Stuart, M. H. V., Mihăilă, S. M., Vernooij, R. W. M., Masereeuw, R., & Gerritsen, K. G. F. (2023). Animal Models for Studying Protein-Bound Uremic Toxin Removal—A Systematic Review. International Journal of Molecular Sciences, 24(17), Article 13197. https://doi.org/10.3390/ijms241713197
Faria, J., Ahmed, S., Stamatialis, D., Verhaar, M. C., Masereeuw, R., Gerritsen, K. G. F., & Mihăilă, S. M. (2023). Bioengineered Kidney Tubules Efficiently Clear Uremic Toxins in Experimental Dialysis Conditions. International Journal of Molecular Sciences, 24(15), Article 12435. https://doi.org/10.3390/ijms241512435
Valibeknejad, M., Abdoli, S. M., Alizadeh, R., Mihăilă, S. M., & Raoof, A. (2023). Insights into transport in mucus barrier: Exploring particle penetration through the intestinal mucus layer. Journal of Drug Delivery Science and Technology, 86, 1-10. Article 104752. https://doi.org/10.1016/j.jddst.2023.104752
https://dspace.library.uu.nl/bitstream/handle/1874/430074/1-s2.0-S1773224723006044-main.pdf?sequence=1
Ramada, D. L., de Vries, J., Vollenbroek, J., Noor, N., Ter Beek, O., Mihaila, S., Wieringa, F., Masereeuw, R., Gerritsen, K. G. F., & Stamatialis, D. (2023). Portable, wearable and implantable artificial kidney systems: needs, opportunities and challenges. Nature Reviews Nephrology, 19(8), 481-490. https://doi.org/10.1038/s41581-023-00726-9

2022

Wetenschappelijke publicaties

Lacueva-Aparicio, A., Soares Lindoso, R., Mihaila, S., & Giménez, I. (2022). Role of extracellular matrix components and structure in new renal models in vitro. Frontiers in Physiology, 13, 1-14. Article 1048738. https://doi.org/10.3389%2Ffphys.2022.1048738
Koch, S. E., Verhaegh, F. L. P., Smink, S., Mihăilă, S. M., Bouten, C. V. C., & Smits, A. I. P. M. (2022). Donor Heterogeneity in the Human Macrophage Response to a Biomaterial Under Hyperglycemia In Vitro. Tissue engineering. Part C, Methods, 28(8), 440-456. https://doi.org/10.1089/ten.TEC.2022.0066
Favero, C., Giordano, L., Mihaila, S. M., Masereeuw, R., Ortiz, A., & Sanchez-Niño, M. D. (2022). Postbiotics and Kidney Disease. Toxins, 14(9), 1-17. Article 623. https://doi.org/10.3390/toxins14090623
Genderen, A. M. V., G Valverde, M., Capendale, P. E., Kersten, V., Sendino Garví, E., Schuurmans, C. C. L., Ruelas, M., Soeiro, J. T., Tang, G., Janssen, M. J., Jansen, J., Mihăilă, S. M., Vermonden, T., Zhang, Y. S., & Masereeuw, R. (2022). Co-axial Printing of Convoluted Proximal Tubule for Kidney Disease Modeling. Biofabrication, 14(4), 1-16. Article 044102. https://doi.org/10.1088/1758-5090/ac7895
García Valverde, M., Ferreira Faria, J., Sendino Garví, E., Janssen, M. J., Masereeuw, R., & Mihaila, S. (2022). Organs-on-chip technology: a tool to tackle genetic kidney diseases. Pediatric Nephrology, 37(12), 2985-2996. https://doi.org/10.1007/s00467-022-05508-2
Ahmed, S., Sparidans, R. W., Lu, J., Mihaila, S. M., Gerritsen, K. G. F., & Masereeuw, R. (2022). A robust, accurate, sensitive LC-MS/MS method to measure indoxyl sulfate, validated for plasma and kidney cells. Biomedical Chromatography, 36(5), 1-10. Article e5307. https://doi.org/10.1002/bmc.5307

2021

Wetenschappelijke publicaties

King, J., Mihaila, S. M., Ahmed, S., Truckenmüller, R., Giselbrecht, S., Masereeuw, R., & Carlier, A. (2021). The Influence of OAT1 Density and Functionality on Indoxyl Sulfate Transport in the Human Proximal Tubule: An Integrated Computational and In Vitro Study. Toxins, 13(10), 1-19. Article 674. https://doi.org/10.3390/toxins13100674
Faria, J., Gerritsen, K. G. F., Nguyen, T. Q., Mihaila, S. M., & Masereeuw, R. (2021). Diabetic proximal tubulopathy: Can we mimic the disease for in vitro screening of SGLT inhibitors? European Journal of Pharmacology, 908, 1-11. Article 174378. https://doi.org/10.1016/j.ejphar.2021.174378
Giordano, L., Mihaila, S. M., Eslami Amirabadi, H., & Masereeuw, R. (2021). Microphysiological Systems to Recapitulate the Gut–Kidney Axis. Trends in Biotechnology, 39(8), 811-823. https://doi.org/10.1016/j.tibtech.2020.12.001

2020

Wetenschappelijke publicaties

Pot, M. W., Mihaila, S. M., Te Brinke, D., van der Borg, G., Oosterwijk, E., Daamen, W. F., & van Kuppevelt, T. H. (2020). Introduction of Specific 3D Micromorphologies in Collagen Scaffolds Using Odd and Even Dicarboxylic Acids. ACS Omega, 5(8), 3908-3916. https://doi.org/10.1021/acsomega.9b03350
Liu, K., Veenendaal, T., Wiendels, M., Ruiz-Zapata, A. M., van Laar, J., Kyranas, R., Enting, H., van Cranenbroek, B., Koenen, H. J. P. M., Mihaila, S. M., Oosterwijk, E., & Kouwer, P. H. J. (2020). Synthetic Extracellular Matrices as a Toolbox to Tune Stem Cell Secretome. ACS applied materials & interfaces, 12(51), 56723-56730. https://doi.org/10.1021/acsami.0c16208
Mihaila, S. M., Faria, J., Stefens, M. F. J., Stamatialis, D., Verhaar, M. C., Gerritsen, K. G. F., & Masereeuw, R. (2020). Drugs commonly applied to kidney patients may compromise renal tubular uremic toxins excretion. Toxins, 12(6), Article 391. https://doi.org/10.3390/toxins12060391

2019

Wetenschappelijke publicaties

Liu, K., Mihaila, S. M., Rowan, A., Oosterwijk, E., & Kouwer, P. H. J. (2019). Synthetic Extracellular Matrices with Nonlinear Elasticity Regulate Cellular Organization. Biomacromolecules, 20(2), 826-834. https://doi.org/10.1021/acs.biomac.8b01445
Faria, J., Ahmed, S., Gerritsen, K. G. F., Mihaila, S. M., & Masereeuw, R. (2019). Kidney-based in vitro models for drug-induced toxicity testing. Archives of Toxicology, 93, 3397–3418. https://doi.org/10.1007/s00204-019-02598-0

2018

Wetenschappelijke publicaties

Sloff, M., Janke, H. P., de Jonge, P. K. J. D., Tiemessen, D. M., Kortmann, B. B. M., Mihaila, S. M., Geutjes, P. J., Feitz, W. F. J., & Oosterwijk, E. (2018). The Impact of γ-Irradiation and EtO Degassing on Tissue Remodeling of Collagen-based Hybrid Tubular Templates. ACS Biomaterials Science and Engineering, 4(9), 3282-3290. https://doi.org/10.1021/acsbiomaterials.8b00369
van Gelder, M. K., Mihaila, S. M., Jansen, J., Wester, M., Verhaar, M. C., Joles, J. A., Stamatialis, D., Masereeuw, R., & Gerritsen, K. G. F. (2018). From portable dialysis to a bioengineered kidney. Expert Review of Medical Devices, 15(5), 323-336. https://doi.org/10.1080/17434440.2018.1462697

2017

Wetenschappelijke publicaties

Janke, H. P., Bohlin, J., Lomme, R. M. L. M., Mihaila, S. M., Hilborn, J., Feitz, W. F. J., & Oosterwijk, E. (2017). Bioinspired coupled helical coils for soft tissue engineering of tubular structures - Improved mechanical behavior of tubular collagen type I templates. Acta Biomaterialia, 59, 234-242. https://doi.org/10.1016/j.actbio.2017.06.038
Mihaila, S. M., Resende, M. F., Reis, R. L., Gomes, M. E., & Marques, A. P. (2017). Interactive endothelial phenotype maintenance and osteogenic differentiation of adipose tissue stromal vascular fraction SSEA-4+ -derived cells. Journal of Tissue Engineering and Regenerative Medicine, 11(7), 1998-2013. https://doi.org/10.1002/term.2096

2014

Wetenschappelijke publicaties

Mihaila, S. M., Gaharwar, A. K., Reis, R. L., Khademhosseini, A., Marques, A. P., & Gomes, M. E. (2014). The osteogenic differentiation of SSEA-4 sub-population of human adipose derived stem cells using silicate nanoplatelets. Biomaterials, 35(33), 9087-99. https://doi.org/10.1016/j.biomaterials.2014.07.052
Gaharwar, A. K., Mihaila, S. M., Kulkarni, A. A., Patel, A., Di Luca, A., Reis, R. L., Gomes, M. E., van Blitterswijk, C., Moroni, L., & Khademhosseini, A. (2014). Amphiphilic beads as depots for sustained drug release integrated into fibrillar scaffolds. Journal of controlled release : official journal of the Controlled Release Society, 187, 66-73. https://doi.org/10.1016/j.jconrel.2014.04.035
Gaharwar, A. K., Mukundan, S., Karaca, E., Dolatshahi-Pirouz, A., Patel, A., Rangarajan, K., Mihaila, S. M., Iviglia, G., Zhang, H., & Khademhosseini, A. (2014). Nanoclay-enriched poly(ɛ-caprolactone) electrospun scaffolds for osteogenic differentiation of human mesenchymal stem cells. Tissue Engineering. Part A, 20(15-16), 2088-101. https://doi.org/10.1089/ten.tea.2013.0281
Mihaila, S. M., Popa, E. G., Reis, R. L., Marques, A. P., & Gomes, M. E. (2014). Fabrication of endothelial cell-laden carrageenan microfibers for microvascularized bone tissue engineering applications. Biomacromolecules, 15(8), 2849-60. https://doi.org/10.1021/bm500036a

2013

Wetenschappelijke publicaties

Gaharwar, A. K., Mihaila, S. M., Swami, A., Patel, A., Sant, S., Reis, R. L., Marques, A. P., Gomes, M. E., & Khademhosseini, A. (2013). Bioactive silicate nanoplatelets for osteogenic differentiation of human mesenchymal stem cells. Advanced Materials, 25(24), 3329-36. https://doi.org/10.1002/adma.201300584
Patel, A., Gaharwar, A. K., Iviglia, G., Zhang, H., Mukundan, S., Mihaila, S. M., Demarchi, D., & Khademhosseini, A. (2013). Highly elastomeric poly(glycerol sebacate)-co-poly(ethylene glycol) amphiphilic block copolymers. Biomaterials, 34(16), 3970-3983. https://doi.org/10.1016/j.biomaterials.2013.01.045
Zhang, H., Patel, A., Gaharwar, A. K., Mihaila, S. M., Iviglia, G., Mukundan, S., Bae, H., Yang, H., & Khademhosseini, A. (2013). Hyperbranched polyester hydrogels with controlled drug release and cell adhesion properties. Biomacromolecules, 14(5), 1299-310. https://doi.org/10.1021/bm301825q
Mihaila, S. M., Frias, A. M., Pirraco, R. P., Rada, T., Reis, R. L., Gomes, M. E., & Marques, A. P. (2013). Human adipose tissue-derived SSEA-4 subpopulation multi-differentiation potential towards the endothelial and osteogenic lineages. Tissue Engineering. Part A, 19(1-2), 235-46. https://doi.org/10.1089/ten.TEA.2012.0092
Mihaila, S. M., Gaharwar, A. K., Reis, R. L., Marques, A. P., Gomes, M. E., & Khademhosseini, A. (2013). Photocrosslinkable kappa-carrageenan hydrogels for tissue engineering applications. Advanced healthcare materials, 2(6), 895-907. https://doi.org/10.1002/adhm.201200317