Publicaties
2022
Wetenschappelijke publicaties
Silva, J., Alkan, F., Ramalho, S., Snieckute, G., Prekovic, S., Garcia, A. K., Hernández-Pérez, S., Kammen, R. V. D., Barnum, D., Hoekman, L., Altelaar, M., Zwart, W., Suijkerbuijk, S. J. E., Bekker-Jensen, S., & Faller, W. J. (2022). Ribosome impairment regulates intestinal stem cell identity via ZAKɑ activation. Nature Communications. https://doi.org/10.1038/s41467-022-32220-4
2021
Wetenschappelijke publicaties
Krotenberg Garcia, A., van Rheenen, J., & Suijkerbuijk, S. (2021). Generation of mixed murine organoids to model cellular interactions. STAR Protocols. https://doi.org/10.1016/j.xpro.2021.100997
2020
Wetenschappelijke publicaties
Fumagalli, A., Oost, K., Kester, L., Morgner, J., Bornes, L., Bruens, L., Spaargaren, L., Azkanaz, M., Schelfhorst, T., Beerling, E., Heinz, M., Postrach, D., Seinstra, D., Sieuwerts, A., Martens, J., van der Elst, S., van Baalen, M., Bhowmick, D., Vrisekoop, N., ... van Rheenen, J. (2020). Plasticity of Lgr5-Negative Cancer Cells Drives Metastasis in Colorectal Cancer. Cell Stem Cell. https://doi.org/10.1016/j.stem.2020.02.008
Bruens, L., Ellenbroek, S. I. J., Suijkerbuijk, S. J. E., Azkanaz, M., Hale, A. J., Toonen, P., Flanagan, D. J., Sansom, O. J., Snippert, H. J., & Rheenen, J. V. (2020). Calorie Restriction Increases the Number of Competing Stem Cells and Decreases Mutation Retention in the Intestine. Cell Reports. https://doi.org/10.1016/j.celrep.2020.107937
Garcia, A. K., Fumagalli, A., Le, H. Q., Sansom, O. J., Rheenen, J. V., & Suijkerbuijk, S. J. E. (2020). Active elimination of intestinal cells drives oncogenic growth in organoids. Cell Reports. https://doi.org/10.1101/2020.11.14.378588
2018
Wetenschappelijke publicaties
Fumagalli, A., Suijkerbuijk, S. J. E., Begthel, H., Beerling, E., Oost, K. C., Snippert, H. J., Rheenen, J. V., & Drost, J. (2018). A surgical orthotopic organoid transplantation approach in mice to visualize and study colorectal cancer progression. Nature Protocols. https://doi.org/10.1038/nprot.2017.137
2017
Wetenschappelijke publicaties
Fumagalli, A., Drost, J., Suijkerbuijk, S. J. E., Van Boxtel, R., De Ligt, J., Offerhaus, G. J., Begthel, H., Beerling, E., Tan, E. H., Sansom, O. J., Cuppen, E., Clevers, H., & Van Rheenen, J. (2017). Genetic dissection of colorectal cancer progression by orthotopic transplantation of engineered cancer organoids. Proceedings of the National Academy of Sciences of the United States of America. https://doi.org/10.1073/pnas.1701219114
Suijkerbuijk, S., & van Rheenen, J. (2017). From good to bad: Intravital imaging of the hijack of physiological processes by cancer cells. Developmental Biology. https://doi.org/10.1016/j.ydbio.2017.04.015
2016
Wetenschappelijke publicaties
Suijkerbuijk, S. J. E., Kolahgar, G., Kucinski, I., & Piddini, E. (2016). Cell competition drives the growth of intestinal adenomas in Drosophila. Current Biology. https://doi.org/10.1016/j.cub.2015.12.043