Publicaties
2022
Wetenschappelijke publicaties
philippens, I., Böszörményi, K., Wubben, J. A. M., Fagrouch, Z. C., Driel, N. V., Mayenburg, A., Lozovagia, D., Roos, E., Schurink, B., Bugiani, M., Bontrop, R. E., Jinte, Bogers, W., Geus-Oei, L-F. D., Langermans, J., Verschoor, E., Stammes, M., & Verstrepen, B. E. (2022). Brain Inflammation and Intracellular α-Synuclein Aggregates in Macaques after SARS-CoV-2 Infection. Viruses, 14(4), 1-15. [776]. https://doi.org/10.3390/v14040776
2021
Wetenschappelijke publicaties
Stammes, M. A., Lee, J. H., Meijer, L., Naninck, T., Doyle-Meyers, L. A., White, A. G., Borish, H. J., Hartman, A. L., Alvarez, X., Ganatra, S., Kaushal, D., Bohm, R. P., le Grand, R., Scanga, C. A., Langermans, J. A. M., Bontrop, R. E., Finch, C. L., Flynn, J. L., Calcagno, C., ... Kuhn, J. H. (2021). Medical imaging of pulmonary disease in SARS-CoV-2-exposed non-human primates. Trends in Molecular Medicine. https://doi.org/10.1016/j.molmed.2021.12.001
de Groot, N. G., Heijmans, C. M. C., Bezstarosti, S., Bruijnesteijn, J., Haasnoot, G. W., Mulder, A., Claas, F. H. J., Heidt, S., & Bontrop, R. E. (2021). Two Human Monoclonal HLA-Reactive Antibodies Cross-React with Mamu-B*008, a Rhesus Macaque MHC Allotype Associated with Control of Simian Immunodeficiency Virus Replication. Journal of Immunology, 206(8), 1957-1965. https://doi.org/10.4049/jimmunol.2001405
Bruijnesteijn, J., van der Wiel, M., de Groot, N. G., & Bontrop, R. E. (2021). Rapid Characterization of Complex Killer Cell Immunoglobulin-Like Receptor (KIR) Regions Using Cas9 Enrichment and Nanopore Sequencing. Frontiers in Immunology, 12, 1-14. [722181]. https://doi.org/10.3389/fimmu.2021.722181
Storm, L., Bruijnesteijn, J., de Groot, N. G., & Bontrop, R. E. (2021). The Genomic Organization of the LILR Region Remained Largely Conserved Throughout Primate Evolution: Implications for Health And Disease. Frontiers in Immunology, 12, 1-19. [716289]. https://doi.org/10.3389/fimmu.2021.716289
Böszörményi, K., Stammes, M., Fagrouch, Z. C., Kiemenyi-Kayere, G., Niphuis, H., Mortier, D., Driel, N. V., Nieuwenhuis, I., Vervenne, R. A. W., Haaksma, T., Ouwerling, B., Adema, D., Acar, R. F., Zuiderwijk-Sick, E., Meijer, L., Mooij, P., Remarque, E. J., Oostermeijer, H., Hoste, A. C. R., ... Verstrepen, B. E. (2021). The Post-Acute Phase of SARS-CoV-2 Infection in Two Macaque Species Is Associated with Signs of Ongoing Virus Replication and Pathology in Pulmonary and Extrapulmonary Tissues. Viruses, 13(8), 1-22. [1673]. https://doi.org/10.3390/v13081673
2020
Wetenschappelijke publicaties
Genzel, L., Adan, R., Berns, A., van den Beucken, J. J. J. P., Blokland, A., Boddeke, E. H. W. G. M., Bogers, W. M., Bontrop, R., Bulthuis, R., Bousema, T., Clevers, H., Coenen, T. C. J. J., van Dam, A. M., Deen, P. M. T., van Dijk, K. W., Eggen, B. J. L., Elgersma, Y., Erdogan, I., Englitz, B., ... Homberg, J. R. (2020). Correction: How the COVID-19 pandemic highlights the necessity of animal research. Current Biology, 30(21), 4328. https://doi.org/10.1016/j.cub.2020.10.033
De Groot, N. G., Heijmans, C. M. C., De Ru, A. H., Otting, N., Koning, F., Van Veelen, P. A., Bontrop, R. E., & Kirchhoff, F. (Ed.) (2020). The HLA A03 Supertype and Several Pan Species Major Histocompatibility Complex Class I A Allotypes Share a Preference for Binding Positively Charged Residues in the F Pocket: Implications for Controlling Retroviral Infections. Journal of Virology, 94(9), [ e01960-19]. https://doi.org/10.1128/JVI.01960-19
Bruijnesteijn, J., De Groot, N., Van Der Wiel, M. K. H., Otting, N., De Vos-rouweler, A. J. M., De Groot, N. G., & Bontrop, R. E. (2020). Unparalleled Rapid Evolution of KIR Genes in Rhesus and Cynomolgus Macaque Populations. Journal of Immunology, 204(7), 1770-1786. https://doi.org/10.4049/jimmunol.1901140
Gokhman, D., Nissim-rafinia, M., Agranat-tamir, L., Housman, G., García-pérez, R., Lizano, E., Cheronet, O., Mallick, S., Nieves-colón, M. A., Li, H., Alpaslan-roodenberg, S., Novak, M., Gu, H., Osinski, J. M., Ferrando-bernal, M., Gelabert, P., Lipende, I., Mjungu, D., Kondova, I., ... Carmel, L. (2020). Differential DNA methylation of vocal and facial anatomy genes in modern humans. Nature Communications, 11(1), [1189 ]. https://doi.org/10.1038/s41467-020-15020-6
Walter, L., & Bontrop, R. (2020). Editorial: Comparative Genetics of NK Cell Receptor Families in Relation to MHC Class I Ligands and Their Function. Frontiers in Immunology, 11, [561]. https://doi.org/10.3389/fimmu.2020.00561
De Groot, N. G., & Bontrop, R. E. (2020). COVID-19 pandemic: is a gender-defined dosage effect responsible for the high mortality rate among males? Immunogenetics, 72(5), 275-277. https://doi.org/10.1007/s00251-020-01165-7
Heijmans, C. M. C., Groot, N. G., & Bontrop, R. E. (2020). Comparative genetics of the major histocompatibility complex in humans and nonhuman primates. International Journal of Immunogenetics, 47(3), 243-260. https://doi.org/10.1111/iji.12490
Vangenot, C., Nunes, J. M., Doxiadis, G. M., Poloni, E. S., Bontrop, R. E., De Groot, N. G., & Sanchez-mazas, A. (2020). Similar patterns of genetic diversity and linkage disequilibrium in Western chimpanzees (Pan troglodytes verus) and humans indicate highly conserved mechanisms of MHC molecular evolution. BMC Evolutionary Biology, 20(1), [119]. https://doi.org/10.1186/s12862-020-01669-6
Bruijnesteijn, J., De Groot, N. G., & Bontrop, R. E. (2020). The Genetic Mechanisms Driving Diversification of the KIR Gene Cluster in Primates. Frontiers in Immunology, 11, [582804]. https://doi.org/10.3389/fimmu.2020.582804
Otting, N., De Groot, N. G., & Bontrop, R. E. (2020). Evolution of HLA-F and its orthologues in primate species: a complex tale of conservation, diversification and inactivation. Immunogenetics, 72, 475–487. https://doi.org/10.1007/s00251-020-01187-1
Genzel, L., Adan, R., Berns, A., van den Beucken, J., Blokland, A., Boddeke, E. H. W. G. M., Bogers, W. M., Bontrop, R., Bulthuis, R., Bousema, T., Clevers, H., Coenen, T. C. J. J., Dam, A-M. V., Deen, P. M. T., van Dijk, K. W., Eggen, B. J. L., Elgersma, Y., Erdogan, I., Englitz, B., ... Homberg, J. R. (2020). How the COVID-19 pandemic highlights the necessity of animal research. Current Biology, 30(18), R1014-R1018. https://doi.org/10.1016/j.cub.2020.08.030
Otting, N., de Groot, N. G., & Bontrop, R. E. (2020). Full-length MHC class II alleles in three New World monkey species. HLA, 95(2), 163-165. https://doi.org/10.1111/tan.13757
2019
Wetenschappelijke publicaties
Otting, N., de Groot, N. G., & Bontrop, R. E. (2019). Limited MHC class II gene polymorphism in the West African chimpanzee is distributed maximally by haplotype diversity. Immunogenetics, 71(1), 13-23. https://doi.org/10.1007/s00251-018-1080-4
de Winter, I. I., Qurkhuli, T., de Groot, N., de Vos-Rouweler, A. J. M., van Hooft, P., Heitkönig, I. M. A., Prins, H. H. T., Bontrop, R. E., & Doxiadis, G. G. M. (2019). Determining Mhc-DRB profiles in wild populations of three congeneric true lemur species by noninvasive methods. Immunogenetics, 71(2), 97-107. https://doi.org/10.1007/s00251-018-1085-z
de Groot, N., Groen, R., Orie, V., Bruijnesteijn, J., de Groot, N. G., Doxiadis, G. G. M., & Bontrop, R. E. (2019). Analysis of macaque BTN3A genes and transcripts in the extended MHC: conserved orthologs of human γδ T cell modulators. Immunogenetics, 71(8-9), 545-559. https://doi.org/10.1007/s00251-019-01126-9
de Groot, N. G., Otting, N., Maccari, G., Robinson, J., Hammond, J. A., Blancher, A., Lafont, B. A. P., Guethlein, L. A., Wroblewski, E. E., Marsh, S. G. E., Shiina, T., Walter, L., Vigilant, L., Parham, P., O’Connor, D. H., & Bontrop, R. E. (2019). Correction to: Nomenclature report 2019: major histocompatibility complex genes and alleles of great and small ape and old and new world monkey species (Immunogenetics, (2019), 10.1007/s00251-019-01132-x). Immunogenetics, 72, 131-132. https://doi.org/10.1007/s00251-019-01146-5
de Groot, N. G., Otting, N., Maccari, G., Robinson, J., Hammond, J. A., Blancher, A., Lafont, B. A. P., Guethlein, L. A., Wroblewski, E. E., Marsh, S. G. E., Shiina, T., Walter, L., Vigilant, L., Parham, P., O’Connor, D. H., & Bontrop, R. E. (2019). Nomenclature report 2019: major histocompatibility complex genes and alleles of Great and Small Ape and Old and New World monkey species. Immunogenetics, 72, 25–36. https://doi.org/10.1007/s00251-019-01132-x
Bruijnesteijn, J., de Groot, N. G., Otting, N., Maccari, G., Guethlein, L. A., Robinson, J., Marsh, S. G. E., Walter, L., O’Connor, D. H., Hammond, J. A., Parham, P., & Bontrop, R. E. (2019). Nomenclature report for killer-cell immunoglobulin-like receptors (KIR) in macaque species: new genes/alleles, renaming recombinant entities and IPD-NHKIR updates. Immunogenetics, 72(1-2), 37-47. https://doi.org/10.1007/s00251-019-01135-8
Kesmir, C., & Bontrop, R. (2019). Immunogenetics special issue 2020: nomenclature, databases, and bioinformatics in immunogenetics. Immunogenetics, 72(1), 1-3. https://doi.org/10.1007/s00251-019-01150-9
2018
Wetenschappelijke publicaties
Otting, N., de Groot, N. G., & Bontrop, R. E. (2018). Correction to: Limited MHC class II gene polymorphism in the West African chimpanzee is distributed maximally by haplotype diversity (Immunogenetics, (2018), 10.1007/s00251-018-1080-4). Immunogenetics, 70(10), 689-691. https://doi.org/10.1007/s00251-018-1089-8
2017
Wetenschappelijke publicaties
Sterck, E. H. M., Bontrop, R. E., Groot, N., de Vos-Rouweler, A. J. M., & Doxiadis, G. G. M. (2017). No postcopulatory selection against MHC-homozygous offspring: Evidence from a pedigreed captive rhesus macaque colony. Molecular Ecology, 26(14), 3785-3793. https://doi.org/10.1111/mec.14153
Maccari, G., Robinson, J., Ballingall, K., Guethlein, L. A., Grimholt, U., Kaufman, J., Ho, C-S., de Groot, N. G., Flicek, P., Bontrop, R. E., Hammond, J. A., & Marsh, S. G. E. (2017). IPD-MHC 2.0: an improved inter-species database for the study of the major histocompatibility complex. Nucleic Acids Research, 45(D1), D860-D864. https://doi.org/10.1093/nar/gkw1050
Otting, N., van der Wiel, M. K. H., de Groot, N., de Vos-Rouweler, A. J. M., de Groot, N. G., Doxiadis, G. G. M., Wiseman, R. W., O'Connor, D. H., & Bontrop, R. E. (2017). The orthologs of HLA-DQ and -DP genes display abundant levels of variability in macaque species. Immunogenetics, 69(2), 87-99. https://doi.org/10.1007/s00251-016-0954-6
2016
Wetenschappelijke publicaties
Gallego, A., Melé, M., Balcells, I., García-Ramallo, E., Torruella-Loran, I., Fernández-Bellon, H., Abelló, T., Kondova, I., Bontrop, R., Hvilsom, C., Navarro, A., Marquès-Bonet, T., & Espinosa-Parrilla, Y. (2016). Functional Implications of Human-Specific Changes in Great Ape microRNAs. PLoS One, 11(4), [e0154194]. https://doi.org/10.1371/journal.pone.0154194
Sanchez-Delgado, M., Court, F., Vidal, E., Medrano, J., Monteagudo-Sánchez, A., Martin-Trujillo, A., Tayama, C., Iglesias-Platas, I., Kondova, I., Bontrop, R., Poo-Llanillo, M. E., Marques-Bonet, T., Nakabayashi, K., Simón, C., & Monk, D. (2016). Human Oocyte-Derived Methylation Differences Persist in the Placenta Revealing Widespread Transient Imprinting. PLoS Genetics, 12(11), [e1006427]. https://doi.org/10.1371/journal.pgen.1006427
de Groot, N. G., Heijmans, C. M. C., van der Wiel, M. K. H., Blokhuis, J. H., Mulder, A., Guethlein, L. A., Doxiadis, G. G. M., Claas, F. H. J., Parham, P., & Bontrop, R. E. (2016). Complex MHC Class I Gene Transcription Profiles and Their Functional Impact in Orangutans. Journal of Immunology, 196(2), 750-8. https://doi.org/10.4049/jimmunol.1500820
Otting, N., van der Wiel, M. K. H., Doxiadis, G. G. M., & Bontrop, R. E. (2016). Fifty-one full-length major histocompatibility complex class II alleles in the olive baboon (Papio anubis). HLA, 88(5), 270-271. https://doi.org/10.1111/tan.12906
Vermunt, M. W., Tan, S. C., Castelijns, B., Geeven, G., Reinink, P., de Bruijn, E., Kondova, I., Persengiev, S., Bontrop, R., Cuppen, E., de Laat, W., Creyghton, M. P., & Netherlands Brain Bank (2016). Epigenomic annotation of gene regulatory alterations during evolution of the primate brain. Nature Neuroscience, 9(3), 494–503. https://doi.org/10.1038/nn.4229
2013
Wetenschappelijke publicaties
de Groot, N. G., & Bontrop, R. E. (2013). The HIV-1 pandemic: does the selective sweep in chimpanzees mirror humankind's future? Retrovirology, 10, 53.
Koopman, G., Beenhakker, N., Nieuwenhuis, I., Doxiadis, G. G. M., Mooij, P., Drijfhout, J. W., Koestler, J., Hanke, T., Fagrouch, Z., Verschoor, E. J., Bontrop, R. E., Wagner, R., Bogers, W. M., & Melief, C. J. (2013). DNA/long peptide vaccination against conserved regions of SIV induces partial protection against SIVmac251 challenge. AIDS.
Sudmant, P. H., Huddleston, J., Catacchio, C. R., Malig, M., Hillier, L. W., Baker, C., Mohajeri, K., Kondova, I., Bontrop, R. E., Persengiev, S. P., Antonacci, F., Ventura, M., Prado-Martinez, J., Marques-Bonet, T., & Eichler, E. E. (2013). Evolution and diversity of copy number variation in the great ape lineage. Genome Research, 23, 1373-1382.
Persengiev, S., Kondova, I., & Bontrop, R. E. (2013). Insights on the functional interactions between miRNAs and copy number variations in the aging brain. Frontiers in Neuroscience, 6, 32.
Wiel, M. K., Otting, N., de Groot, N. G., Doxiadis, G. G. M., & Bontrop, R. E. (2013). The repertoire of MHC class I genes in the common marmoset: evidence for functional plasticity. Immunogenetics, 65, 841-849.
Doxiadis, G. G. M., Groot, N., Otting, N., de Vos-Rouweler, A. J., Bolijn, M. J., Heijmans, C. M., de Groot, N. G., van der Wiel, M. K., Remarque, E. J., Vangenot, C., Nunes, J. M., Sanchez-Mazas, A., & Bontrop, R. E. (2013). Haplotype diversity generated by ancient recombination-like events in the MHC of Indian rhesus macaques. Immunogenetics, 65, 569-584.
Prado-Martinez, J., Sudmant, P. H., Kidd, J. M., Li, H., Kelley, J. L., Lorente-Galdos, B., Veeramah, K. R., Woerner, A. E., O'Connor, T. D., Santpere, G., Cagan, A., Theunert, C., Casals, F., Laayouni, H., Munch, K., Hobolth, A., Halager, A. E., Malig, M., Hernandez-Rodriguez, J., ... Marques-Bonet, T. (2013). Great ape genetic diversity and population history. Nature, 499, 471-475.
Leffler, E. M., Gao, Z., Pfeifer, S., Segurel, L., Auton, A., Venn, O., Bowden, R., Bontrop, R. E., Wall, J. D., Sella, G., Donnelly, P., McVean, G., & Przeworski, M. (2013). Multiple instances of ancient balancing selection shared beteen humans and chimpanzees. Science, 339, 1578-1582.
de Groot, N. G., Heijmans, C. M., de Ru, A. H., Hassan, C., Otting, N., Doxiadis, G. G. M., Koning, F. G., van Veelen, P. A., & Bontrop, R. E. (2013). Unique peptide-binding motif for Mamu-B*037:01: an MHC class I allele common to Indian and Chinese rhesus macaques. Immunogenetics, 65, 897-900.
2012
Wetenschappelijke publicaties
de Groot, N. G., Otting, N., Robinson, J., Blancher, A., Lafont, B. A., Marsh, S. G., O'Connor, D. H., Shiina, T., Walter, L., Watkins, D. I., & Bontrop, R. E. (2012). Nomenclature report on the major histocompatibility complex genes and alleles of Greate Ape, Old and New World monkey species. Immunogenetics, 64, 615-631.
Bowden, R., MacFie, T. S., Myers, S. M., Hellenthal, G., Nerrienet, E., Bontrop, R. E., Freeman, C., Donnelly, P., & Mundy, N. I. (2012). Genomic tools for eovlution and conservation in the chimpanzee: Pan troglodytes ellioti is a genetically distinct population. PLoS Genetics, 8.
Doxiadis, G. G. M., Hoof, I., Groot, N., & Bontrop, R. E. (2012). Evolution of HLA-DRB Genes. Molecular Biology and Evolution, 29, 3843-3853.
Verstrepen, B. E., de Groot, N. G., Groothuismink, Z. M., Verschoor, E. J., Groen, R. A., Bogers, W. M., Janssen, H. L., Mooij, P., Bontrop, R. E., Koopman, G., & Boonstra, A. (2012). Evaluation of IL-28B polymorphysms and serum I_10 in Hepatitis C infected chimpanzees. PLoS One, 7, e46645.
Auton, A., Fledel-Alon, A., Pfeifer, S., Venn, O., Segurel, L., Street, T., Leffler, E. M., Bowden, R., Aneas, I., Broxholme, J., Humburg, P., Iqbal, Z., Lunter, T., Maller, J., Hernandez, R. D., Melton, C., Venkat, A., Nobrega, M. A., Bontrop, R. E., ... McVean, G. (2012). A fine-scale chimpanzee genetic map from population sequencing. Science, 336, 193-198.
Otting, N., Groot, N., de Vos-Rouweler, A. J., Louwerse, A. L., Doxiadis, G. G. M., & Bontrop, R. E. (2012). Multilocus definition of MHC haplotypes in pedigreed cynomolgus macaques (Macaca fascicularis). Immunogenetics, 64, 755-765.
Schneider, E., Mayer, S., El Hajj, N., Jensen, L. R., Kuss, A. W., Zischler, H., Kondova, I., Bontrop, R. E., Navarro, B., Fuchs, E., Zechner, U., & Haaf, T. (2012). Methylation and expression analyses of the 7q autism susceptibility locus genes MEST, COPG2, and TSGA14 in human and anthropoid primate cortices. Cytogenetic and Genome Research, 136, 278-287.
2011
Wetenschappelijke publicaties
Doxiadis, G. G. M., de Vos-Rouweler, A. J., De Groot, N., Otting, N., & Bontrop, R. E. (2011). DR haplotype diversity of the cynomolgus macaque as defined by its transcriptome. Immunogenetics, 0.
de Groot, N. G., Heijmans, C. M., Koopman, G., Verschoor, E. J., Bogers, W. M., & Bontrop, R. E. (2011). TRIM5 allelic polymorphism in macaque species/populations of differnt geographic origins: its impact on SIV vaccine studies. Tissue Antigens, 78, 256-262.
Blokhuis, J. H., Wiel, M. K., Doxiadis, G. G. M., & Bontrop, R. E. (2011). The expreme plasticity of killer cell Ig-like receptor (KIR) haplotypes differentiates rhesus macaques from humans. European Journal of Immunology, 41, 2719-2728.
Persengiev, S. P., Kondova, I., Otting, N., Koeppen, A. H., & Bontrop, R. E. (2011). Genome-wide analysis of miRNA expression reveals a potential role for miR-144 in brain aging and spinocerebellar ataxia pathogenesis. Neurobiology of Aging, 32, 2316-2317.
Otting, N., Morner, A., & Bontrop, R. E. (2011). Novel major histocompatibility complex class I alleles extracted from two rhesus macaque populations. Tissue Antigens, 77, 79-80.
Doxiadis, G. G. M., de Vos-Rouweler, A. J., De Groot, N., Otting, N., Blokhuis, J. H., & Bontrop, R. E. (2011). Genomic plasticity of the MHC class I A region in rhesus macaques: extensive haplotype diversity at the population level as revealed by microsatellites. Immunogenetics, 63, 73-83.
van Deutekom, H. W. M., Hoof, I., Bontrop, R. E., & Kesmir, C. (2011). A comparative analysis of viral peptides presented by contemporary human and chimpanzee MHC class I molecules. Journal of Immunology, 187, 5995-6001.
2010
Overige resultaten
Blokhuis, J. H., van der Wiel, M. K., Doxiadis, G. G. M., & Bontrop, R. E. (2010). The mosaic of KIR haplotypes in rhesus macaques. Immunogenetics, 62(DOI> MEDLINE. DownLoad PDF), 295-306.
Otting, N., Morner, A., & Bontrop, R. E. (2010). Novel major histocompatibility complex class I alleles extraxted from two rhesus macaque populations. Tissue Antigens, 77(DOI. MEDLINE. DownLoad PDF.), 78-80.
Doxiadis, G. G. M., Groot, N., Otting, N., Blokhuis, J. H., & Bontrop, R. E. (2010). Genomic plasticity of the MHC class 1 A region in rhesus macaques: extensive haplotype diversity at the population level as revealed by microsatellites. Immunogenetics, 63(DOI. MEDLINE. DownLoad PDF.), 73-83.
Meyers, S., Bowden, R., Tumian, A., Bontrop, R. E., Freeman, C., MacFie, T. S., McVean, G., & Donnelly, P. (2010). Drive against hotspot motifs in primates implicates the PRDM9 gene in meiotic recombination. Science and Technology Libraries, 327(DOI. MEDLINE. DownLoad PDF.), 876-879.
Marsh, S. G., Albert, E. D., Bodmer, W. F., Bontrop, R. E., Dupunt, B., Erlich, H. A., Fernandez-Vina, M., Geraghty, D. E., Holdsworth, R., Hurley, C. K., Lau, M., Lee, K. W., Mach, B., Maiers, M., Mayr, W. R., Muller, C. R., Parham, P., Petersdorf, E. W., Sasazuki, T., ... Trowsdale, J. (2010). An update to HLA nomenclature. Bone Marrow Transplantation, 45(DOI. MEDLINE. DownLoad PDF.), 846-848.
Menheniott, T. R., Peterson, A. J., O'Connor, L., Lee, K. S., Kalantzis, A., Kondova, I., Bontrop, R. E., Bell, K. M., & Giraud, A. S. (2010). A novel gastrokine, Gkn3, marks gastric atrophy and shows evidence of adaptive gene loss in humans. Gastroenterology, 138(DOI. MEDLINE. DownLoad PDF.), 1823-1835.
Bontrop, R. E. (2010). Verschil moet er zijn. Universiteit Utrecht.
https://dspace.library.uu.nl/bitstream/handle/1874/204071/OratieRB.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/204071/OratieRB.pdf?sequence=1
Marsh, S. G., Albert, E. D., Bodmer, W. F., Bontrop, R. E., Dupont, B., Erlich, H. A., Fernandez-Vina, M., Geraghty, D. E., Holdsworth, R., Hurley, C. K., Lau, M., Lee, K. W., Mach, B., Maiers, M., Mayr, W. R., Muller, C. R., Parham, P., Petersdorf, E. W., Sasazuki, T., ... Trowsdale, J. (2010). Nomenclature for factors of the HLA system. Tissue Antigens, 75(DOI. MEDLINE. DownLoad PDF.), 291-455.
Doxiadis, G. G. M., Groot, N., de Groot, N. G., Rotmans, G., de Vos-Rouweler, A. J., & Bontrop, R. E. (2010). Extensive DRB region diversity in cynomolgus macaques: recombination as a driving force. Immunogenetics, 62(DOI. MEDLINE. DownLoad PDF), 137-147.
de Groot, N. G., Heijmans, C. M., Zoet, Y. M., de Ru, A. H., Verreck, F. A. W., van Veelen, P. A., Drijfhout, J. W., Doxiadis, G. G. M., Remarque, E. J., Doxiadis, I. I., Rood, J. J., Koning, F., & Bontrop, R. E. (2010). AIDS-protective HLA-B*27/B*57 and chimpanzee MHC class I molecules target analogous conserved areas of HIV-1/SIVcpz. Proceedings of the National Academy of Sciences of the United States of America, 107(DOI. MEDLINE. DownLoad PDF), 15175-15180.
Nieuwenhuis, I., Beenhakker, N., Bogers, W. M., Otting, N., Bontrop, R. E., Dubois, P., Mooij, P., Heeney, J. L., & Koopman, G. (2010). No difference in Gag and Env immune-response profiles between vaccinated and non-vaccinated rhesus macaques that control immunodeficiency virus replication. Journal of General Virology, 91(DOI. MEDLINE. DownLoad PDF), 2974-2984.
2001
Wetenschappelijke publicaties
't Hart, L. A., Brok, H. P. M., Amor, S., & Bontrop, R. E. (2001). The major histocompatibility complex influences the ethiopathogenesis of MS-like disease in primates at multiple levels. Human Immunology, 62, 1371-1381.
2000
Wetenschappelijke publicaties
't Hart, L. A., van Meurs, M., Brok, H. P. M., Massacesi, L., Bauer, J., Boon, L., Bontrop, R. E., & Laman, J. D. (2000). A new primate model for multiple sclerosis in the common marmoset. Immunology Today, 21, 290-297.
Brok, H. P. M., Uccelli, A., Kerlero de Rosbo, N., Bontrop, R. E., Roccatagliata, L., de Groot, N. G., Capello, E., Laman, J. D., Nicolay, K., Mancardi, G. L., Ben-Nun, A., & 't Hart, L. A. (2000). Myelin/oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis in common marmosets: The encephalitogenic T cell epitope pMOG24-36 is presented by a monomorphic MHC class II molecule. Journal of Immunology, 165, 1093-1101.
1998
Wetenschappelijke publicaties
't Hart, L. A., Bauer, J., Muller, H. J., Melchers, B. P. C., Nicolay, K., Bontrop, R. E., Lassmann, H., & Massacesi, L. (1998). Experimental autoimmune encephalomyelitis in the common marmose (Callithrix jacchus) induced without Bordatella pertussis. Analysis of brain white matter lesions with MRI and histology. American Journal of Pathology, 153, 649-663.
Otting, N., Doxiadis, G. G. M., Versluis, L., de Groot, N. G., Anholts, J., Verduin, W., Rozemuller, E. H., Claas, F., Tilanus, M. G. J., & Bontrop, R. E. (1998). Characterization and Distribution of MHC-DPB1 alleles in chimpanzee and rhesus macaque populations. Human Immunology, 59, 656-664.
1997
Wetenschappelijke publicaties
't Hart, L. A., Elferink, D. G., Drijfhout, J. W., Storm, G., van Bloois, L., Bontrop, R. E., & de Vries, R. R. P. (1997). Liposome-mediated peptide loading of MHC-DR molecules in vivo. FEBS Letters, 409, 91-95.