Dr. Q.G. (Quentin) Faucher

David de Wiedgebouw
Universiteitsweg 99
3584 CG Utrecht

Dr. Q.G. (Quentin) Faucher

Onderzoeker
Pharmacology
q.g.faucher@uu.nl

Publicaties

2025

Wetenschappelijke publicaties

Petit, I., Faucher, Q., Bernard, J. S., Giunchi, P., Humeau, A., Sauvage, F. L., Marquet, P., Védrenne, N., & Di Meo, F. (2025). Proximal tubule-on-chip as a model for predicting cation transport and drug transporter dynamics. Scientific Reports, 15(1), 2580. https://doi.org/10.1038/s41598-025-85653-4
https://research-portal.uu.nl/ws/files/255295632/s41598-025-85653-4.pdf

2023

Wetenschappelijke publicaties

Faucher, Q., Stéphanie Chadet, Antoine Humeau, Sauvage, F.-L., Arnion, H., Gatault, P., Buchler, M., Roger, S., Lawson, R., Marquet, P., & Barin-Le Guellec, C. (2023). Impact of hypoxia and reoxygenation on the extra/intracellular metabolome and on transporter expression in a human kidney proximal tubular cell line. Metabolomics, 19. https://doi.org/10.1007/s11306-023-02044-4
https://dspace.library.uu.nl/bitstream/handle/1874/435896/s11306-023-02044-4.pdf?sequence=1
Aouad, H., Faucher, Q., Sauvage, F.-L., Pinault, E., Barrot, C.-C., Arnion, H., Essig, M., & Marquet, P. (2023). A multi-omics investigation of tacrolimus off-target effects on a proximal tubule cell-line. Pharmacological Research, 192, Article 106794. https://doi.org/10.1016/j.phrs.2023.106794
https://dspace.library.uu.nl/bitstream/handle/1874/428668/1_s2.0_S1043661823001500_main.pdf?sequence=1
Faucher, Q., van der Made, T. K., De Lange, E., & Masereeuw, R. (2023). Blood-brain barrier perturbations by uremic toxins: key contributors in chronic kidney disease-induced neurological disorders? European Journal of Pharmaceutical Sciences, 187, 1-8. Article 106462. https://doi.org/10.1016/j.ejps.2023.106462
https://dspace.library.uu.nl/bitstream/handle/1874/429610/1_s2.0_S0928098723000921_main.pdf?sequence=1
Janaszkiewicz, A., Tóth, Á., Faucher, Q., Arnion, H., Védrenne, N., Barin-Le Guellec, C., Marquet, P., & Florent , D. M. (2023). Substrate binding and lipid-mediated allostery in the human organic anion transporter 1 at the atomic-scale. Biomedicine and Pharmacotherapy, 160, 1-10. Article 114342. https://doi.org/10.1016/j.biopha.2023.114342
https://dspace.library.uu.nl/bitstream/handle/1874/427055/Substrate_binding_and_lipid_mediated_allostery_in_the_human_organic_anion_transporter_1_at_the_atomic_scale.pdf?sequence=1

2022

Wetenschappelijke publicaties

Jardou, M., Brossier, C., Kenza, G., Faucher, Q., & Lawson, R. (2022). Pharmacological hypothesis: A recombinant probiotic for taming bacterial β-glucuronidase in drug-induced enteropathy. Pharmacology Research and Perspectives, 10(5), 1-7. Article e00998. https://doi.org/10.1002/prp2.998
https://dspace.library.uu.nl/bitstream/handle/1874/426307/Pharmacology_Res_Perspec_2022_Jardou_Pharmacological_hypothesis_A_recombinant_probiotic_for_taming_bacterial_.pdf?sequence=1
Faucher, Q., Jardou, M., Brossier, C., Picard, N., Marquet, P., & Lawson, R. (2022). Is Intestinal Dysbiosis-Associated With Immunosuppressive Therapy a Key Factor in the Pathophysiology of Post-Transplant Diabetes Mellitus? Frontiers in Endocrinology, 13, 1-9. Article 898878. https://doi.org/10.3389/fendo.2022.898878
https://dspace.library.uu.nl/bitstream/handle/1874/426306/fendo_13_898878.pdf?sequence=1
Janaszkiewicz, A., Tóth, Á., Faucher, Q., Marving , M., Chantemargue, B., Barin-Le Guellec, C., Marquet, P., & Florent , D. M. (2022). Insights into the structure and function of the human organic anion transporter 1 in lipid bilayer membranes. Scientific Reports, 12, 1-15. Article 7057. https://doi.org/10.1038/s41598-022-10755-2
https://dspace.library.uu.nl/bitstream/handle/1874/426305/s41598_022_10755_2.pdf?sequence=1
Faucher, Q., Alarcan, H., Sauvage, F.-L., Forestier, L., Miquelestorena-Standley, E., Nadal-Desbarats, L., Arnion, H., Venhard, J.-C., Brichart, N., Bruyère, F., Marquet, P., & Barin-Le Guellec, C. (2022). Perfusate Metabolomics Content and Expression of Tubular Transporters During Human Kidney Graft Preservation by Hypothermic Machine Perfusion. Transplantation, 106(9), 1831-1843. https://doi.org/10.1097/TP.0000000000004129
https://dspace.library.uu.nl/bitstream/handle/1874/426304/Perfusate_Metabolomics_Content_and_Expression_of.26.pdf?sequence=1

2020

Wetenschappelijke publicaties

Faucher, Q., Alarcan, H., Marquet, P., & Barin-Le Guellec, C. (2020). Effects of Ischemia-Reperfusion on Tubular Cell Membrane Transporters and Consequences in Kidney Transplantation. Journal of Clinical Medicine, 9(8), Article 2610. https://doi.org/10.3390/jcm9082610

2019

Wetenschappelijke publicaties

Burat, B., Faucher, Q., Čechová, P., Arnion, H., Di Meo, F., Sauvage, FL., Marquet, P., & Essig, M. (2019). Cyclosporine A inhibits MRTF-SRF signaling through Na+/K+ ATPase inhibition and actin remodeling. FASEB BioAdvances, 1(9), 561-578. https://doi.org/10.1096/fba.2019-00027