Sleutelpublicaties
Perdijk, O., Butler, A., Macowan, M., Chatzis, R., Bulanda, E., Grant, R. D., Harris, N. L., Wypych, T. P., & Marsland, B. J. (2024). Antibiotic-driven dysbiosis in early life disrupts indole-3-propionic acid production and exacerbates allergic airway inflammation in adulthood. Immunity, 57(8), 1939-1954.e7. [DOI]
Perdijk, O., Azzoni, R., & Marsland, B. J. (2024). The microbiome: an integral player in immune homeostasis and inflammation in the respiratory tract. Physiological Reviews, 104(2), 835-879. [DOI]
Wypych, T. P., Pattaroni, C., Perdijk, O., Yap, C., Trompette, A., Anderson, D., Creek, D. J., Harris, N. L., & Marsland, B. J. (2021). Microbial metabolism of l-tyrosine protects against allergic airway inflammation. Nature Immunology, 22(3), 279-286. [DOI]
Publicaties
2025
Wetenschappelijke publicaties
Ding, Z., Adam, W.-V., Downling, M. R., Dvorscek, A. R., Pitt, C., Mulder, J., O'Donnell, K., McKenzie, C., Karaviotis, A. B., Scrofani, J., Perdijk, O., Hill, D. L., Quast , I., Tarlinton, D. M., Allen, C. D. C., & Robinson, M. J. (2025). Long-lived IgE plasma cells persist in secondary lymphoid tissues using a navitoclax-sensitive survival program. Immunity, 58(11). [Portal]
2024
Wetenschappelijke publicaties
Wang, H., Barry, K., Zaini, A., Coakley, G., Moyat, M., Daunt, C. P., Wickramasinghe, L. C., Azzoni, R., Chatzis, R., Yumnam, B., Camberis, M., Le Gros, G., Perdijk, O., Foong, J. P. P., Bornstein, J. C., Marsland, B. J., & Harris, N. L. (2024). Helminth infection driven gastrointestinal hypermotility is independent of eosinophils and mediated by alterations in smooth muscle instead of enteric neurons. PLoS Pathogens, 20(8), Article e1011766. [DOI]
Azzoni, R., Perdijk, O., Harris, N. L., & Marsland, B. J. (2024). Neuroimmunology of the Lung. Annual Review of Immunology, 42(1), 57-81. [DOI]
Perdijk, O., Azzoni, R., & Marsland, B. J. (2024). The microbiome: an integral player in immune homeostasis and inflammation in the respiratory tract. Physiological Reviews, 104(2), 835-879. [DOI]
Perdijk, O., Butler, A., Macowan, M., Chatzis, R., Bulanda, E., Grant, R. D., Harris, N. L., Wypych, T. P., & Marsland, B. J. (2024). Antibiotic-driven dysbiosis in early life disrupts indole-3-propionic acid production and exacerbates allergic airway inflammation in adulthood. Immunity, 57(8), 1939-1954.e7. [DOI]
2022
Wetenschappelijke publicaties
Moyat, M., Lebon, L., Perdijk, O., Wickramasinghe, L. C., Zaiss, M. M., Mosconi, I., Volpe, B., Guenat, N., Shah, K., Coakley, G., Bouchery, T., & Harris, N. L. (2022). Microbial regulation of intestinal motility provides resistance against helminth infection. Mucosal Immunology, 15(6), 1283-1295. [DOI]
Trompette, A., Pernot, J., Perdijk, O., Alqahtani, R. A. A., Domingo, J. S., Camacho-Muñoz, D., Wong, N. C., Kendall, A. C., Wiederkehr, A., Nicod, L. P., Nicolaou, A., von Garnier, C., Ubags, N. D. J., & Marsland, B. J. (2022). Gut-derived short-chain fatty acids modulate skin barrier integrity by promoting keratinocyte metabolism and differentiation. Mucosal Immunology, 15(5), 908-926. [DOI]
2021
Wetenschappelijke publicaties
Wypych, T. P., Pattaroni, C., Perdijk, O., Yap, C., Trompette, A., Anderson, D., Creek, D. J., Harris, N. L., & Marsland, B. J. (2021). Microbial metabolism of l-tyrosine protects against allergic airway inflammation. Nature Immunology, 22(3), 279-286. [DOI]
2019
Wetenschappelijke publicaties
van Splunter, M., Perdijk, O., Fick-Brinkhof, H., Floris-Vollenbroek, E. G., Meijer, B., Brugman, S., Savelkoul, H. F. J., van Hoffen, E., & Joost van Neerven, R. J. (2019). Plasmacytoid dendritic cell and myeloid dendritic cell function in ageing: A comparison between elderly and young adult women. PLoS One, 14(12), Article e0225825. [DOI]
Perdijk, O., Baarlen, P. V., Fernandez-Gutierrez, M. M., Brink, E. V., Schuren, F. H. J., Brugman, S., Savelkoul, H. F. J., Kleerebezem, M., & Neerven, R. J. J. V. (2019). Sialyllactose and galactooligosaccharides promote epithelial barrier functioning and distinctly modulate microbiota composition and short chain fatty acid production in vitro. Frontiers in Immunology, 10, Article 94. [DOI]
Perdijk, O., & Marsland, B. J. (2019). The microbiome: toward preventing allergies and asthma by nutritional intervention. Current Opinion in Immunology, 60, 10-18. [DOI]
2018
Wetenschappelijke publicaties
Perdijk, O., Joost Van Neerven, R. J., Meijer, B., Savelkoul, H. F. J., & Brugman, S. (2018). Induction of human tolerogenic dendritic cells by 3′-sialyllactose via TLR4 is explained by LPS contamination. Glycobiology, 28(3), 126-130. [DOI]
Perdijk, O., van Splunter, M., Savelkoul, H. F. J., Brugman, S., & van Neerven, R. J. J. (2018). Cow's milk and immune function in the respiratory tract: Potential mechanisms. Frontiers in Immunology, 9, Article 143. [DOI]
Perdijk, O., Neerven, R. J. J. V., den Brink, E. V., Savelkoul, H. F. J., & Brugman, S. (2018). Bovine Lactoferrin Modulates Dendritic Cell Differentiation and Function. Nutrients, 10(7), Article 848. [DOI]
Perdijk, O., van Neerven, R. J. J., van den Brink, E., Savelkoul, H. F. J., & Brugman, S. (2018). The oligosaccharides 6’-sialyllactose, 2’-fucosyllactose or galactooligosaccharides do not directly modulate human dendritic cell differentiation or maturation. PLoS One, 13(7), Article e0200356. [DOI]
Van Splunter, M., Perdijk, O., Fick-Brinkhof, H., Feitsma, A. L., Floris-Vollenbroek, E. G., Meijer, B., Brugman, S., Savelkoul, H. F. J., Van Hoffen, E., & Van Neerven, R. J. J. (2018). Bovine lactoferrin enhances TLR7-mediated responses in plasmacytoid dendritic cells in elderly women: Results from a nutritional intervention study with bovine lactoferrin, GOS and Vitamin D. Frontiers in Immunology, 9, Article 2677. [DOI]
2017
Wetenschappelijke publicaties
van Beek, A. A., Hugenholtz, F., Meijer, B., Sovran, B., Perdijk, O., Vermeij, W. P., Brandt, R. M. C., Barnhoorn, S., Hoeijmakers, J. H. J., de Vos, P., Leenen, P. J. M., Hendriks, R. W., & Savelkoul, H. F. J. (2017). Frontline science: Tryptophan restriction arrests B cell development and enhances microbial diversity in WT and prematurely aging Ercc1<sup>-/∆7</sup> mice. Journal of Leukocyte Biology, 101(4), 811-821. [DOI]
Teodorowicz, M., Perdijk, O., Verhoek, I., Govers, C., Savelkoul, H. F. J., Tang, Y., Wichers, H., & Broersen, K. (2017). Optimized triton X-114 assisted lipopolysaccharide (LPS) removal method reveals the immunomodulatory effect of food proteins. PLoS One, 12(3), e0173778. [DOI]
2015
Wetenschappelijke publicaties
Brugman, S., Perdijk, O., van Neerven, R. J. J., & Savelkoul, H. F. J. (2015). Mucosal Immune Development in Early Life: Setting the Stage. Archivum Immunologiae et Therapiae Experimentalis, 63, 251-268. [DOI]
2013
Wetenschappelijke publicaties
Perdijk, O., Arama, C., Giusti, P., Maiga, B., Troye-Blomberg, M., Dolo, A., Doumbo, O., Persson, J.-O., & Boström, S. (2013). Haptoglobin phenotype prevalence and cytokine profiles during Plasmodium falciparum infection in Dogon and Fulani ethnic groups living in Mali. Malaria Journal, 12, 1-12. Article 432. [DOI]