M.R. (Miguel) Leung BSc

David de Wiedgebouw
Universiteitsweg 99
3584 CG Utrecht

M.R. (Miguel) Leung BSc

Onderzoeker
Structural Biochemistry
m.r.leung@uu.nl

Publicaties

2023

Wetenschappelijke publicaties

Leung, M. R., Zeng, J., Wang, X., Roelofs, M. C., Huang, W., Zenezini Chiozzi, R., Hevler, J. F., Heck, A. J. R., Dutcher, S. K., Brown, A., Zhang, R., & Zeev-Ben-Mordehai, T. (2023). Structural specializations of the sperm tail. Cell. https://doi.org/10.1016/j.cell.2023.05.026

2021

Wetenschappelijke publicaties

Leung, M. R., Chiozzi, R. Z., Roelofs, M. C., Hevler, J. F., Ravi, R. T., Maitan, P., Zhang, M., Henning, H., Bromfield, E. G., Howes, S. C., Gadella, B. M., Heck, A. J. R., & Zeev-Ben-Mordehai, T. (2021). In-cell structures of a conserved supramolecular array at the mitochondria-cytoskeleton interface in mammalian sperm. (pp. 1-17). bioRxiv. https://doi.org/10.1101/2021.02.16.431372
Leung, M. R., Ravi, R. T., Gadella, B. M., & Zeev-Ben-Mordehai, T. (2021). Membrane Remodeling and Matrix Dispersal Intermediates During Mammalian Acrosomal Exocytosis. Frontiers in Cell and Developmental Biology, 9, 1-13. [765673]. https://doi.org/10.3389/fcell.2021.765673
Maitan, P. P., Bromfield, E. G., Hoogendijk, R., Leung, M. R., Zeev-Ben-Mordehai, T., van de Lest, C. H., Jansen, J. W. A., Leemans, B., Guimarães, J. D., Stout, T. A. E., Gadella, B. M., & Henning, H. (2021). Bicarbonate-Stimulated Membrane Reorganization in Stallion Spermatozoa. Frontiers in Cell and Developmental Biology, 9, 1-17. [772254]. https://doi.org/10.3389/fcell.2021.772254
Leung, M. R., Zenezini Chiozzi, R., Roelofs, M. C., Hevler, J. F., Ravi, R. T., Maitan, P., Zhang, M., Henning, H., Bromfield, E. G., Howes, S. C., Gadella, B. M., Heck, A. J. R., & Zeev-Ben-Mordehai, T. (2021). In-cell structures of conserved supramolecular protein arrays at the mitochondria-cytoskeleton interface in mammalian sperm. Proceedings of the National Academy of Sciences of the United States of America, 118(45), 1-10. [e2110996118]. https://doi.org/10.1073/pnas.2110996118
Khanal, S., Leung, M. R., Royfman, A., Fishman, E. L., Saltzman, B., Bloomfield-Gadêlha, H., Zeev-Ben-Mordehai, T., & Avidor-Reiss, T. (2021). A dynamic basal complex modulates mammalian sperm movement. Nature Communications, 12(1), 1-11. [3808]. https://doi.org/10.1038/s41467-021-24011-0
Leung, M. R., Roelofs, M. C., Ravi, R. T., Maitan, P., Henning, H., Zhang, M., Bromfield, E. G., Howes, S. C., Gadella, B. M., Bloomfield-Gadêlha, H., & Zeev-Ben-Mordehai, T. (2021). The multi-scale architecture of mammalian sperm flagella and implications for ciliary motility. EMBO Journal, 40(7), 1-17. [e107410]. https://doi.org/10.15252/embj.2020107410
Leung, M. R., & Zeev-Ben-Mordehai, T. (2021). Cryo-electron microscopy of cholinesterases, present and future. Journal of Neurochemistry, 158(6), 1236-1243. https://doi.org/10.1111/jnc.15245

2020

Wetenschappelijke publicaties

Ravi, R. T., Leung, M. R., & Zeev-Ben-Mordehai, T. (2020). Looking back and looking forward: contributions of electron microscopy to the structural cell biology of gametes and fertilization. Biology Open, 10(9), [200186]. https://doi.org/10.1098/rsob.200186

2018

Wetenschappelijke publicaties

Leung, M. R., van Bezouwen, L. S., Schopfer, L. M., Sussman, J. L., Silman, I., Lockridge, O., & Zeev-Ben-Mordehai, T. (2018). Cryo-EM structure of the native butyrylcholinesterase tetramer reveals a dimer of dimers stabilized by a superhelical assembly. Proceedings of the National Academy of Sciences of the United States of America, 115(52), 13270-13275. https://doi.org/10.1073/pnas.1817009115
Zeng, X., Leung, M. R., Zeev-ben-mordehai, T., & Xu, M. (2018). A convolutional autoencoder approach for mining features in cellular electron cryo-tomograms and weakly supervised coarse segmentation. Journal of Structural Biology, 202(2), 150-160. https://doi.org/10.1016/j.jsb.2017.12.015