Publicaties
2021
Wetenschappelijke publicaties
Calero Rodriguez, A., de Grauw, J. C., & van Loon, J. P. A. M. (2021). Effect of different inspired fractions of oxygen on F-shunt and arterial partial pressure of oxygen in isoflurane-anaesthetized and mechanically ventilated Shetland ponies. Veterinary Anaesthesia and Analgesia, 48(6), 930-934. https://doi.org/10.1016/j.vaa.2021.05.005
Calero Rodriguez, A., van Zeeland, Y. R., Schoemaker, N. J., & de Grauw, J. C. (2021). Agreement between invasive and oscillometric arterial blood pressure measurement using a high-definition oscillometric device in normotensive New Zealand White rabbits using two different anaesthetic protocols. Veterinary Anaesthesia and Analgesia, 48(5), 679-687. https://doi.org/10.1016/j.vaa.2021.03.016
Cokelaere, S. M., Groen, W. M. G. A. C., Plomp, S. G. M., Grauw, J. C. D., Midwoud, P. M. V., Weinans, H. H., Lest, C. H. A. V. D., Tryfonidou, M. A., Weeren, P. R. V., & Korthagen, N. M. (2021). Sustained Intra-Articular Release and Biocompatibility of Tacrolimus (FK506) Loaded Monospheres Composed of [PDLA-PEG1000]-b-[PLLA] Multi-Block Copolymers in Healthy Horse Joints. Pharmaceutics, 13(9), 1-18. [1438]. https://doi.org/10.3390/pharmaceutics13091438
2020
Wetenschappelijke publicaties
Kearney, C. M., Korthagen, N. M., Plomp, S. G. M., Labberté, M. C., de Grauw, J. C., van Weeren, P. R., & Brama, P. A. J. (2020). Treatment effects of intra-articular triamcinolone acetonide in an equine model of recurrent joint inflammation. Equine Veterinary Journal. https://doi.org/10.1111/evj.13396
de Grauw, J., & van Loon, T. (2020). Clinical effects of two doses of butorphanol with detomidine for intravenous premedication of healthy warmblood horses. Veterinary Anaesthesia and Analgesia, 47(5), 681-685. https://doi.org/10.1016/j.vaa.2019.11.010
van Loon, J., Verhaar, N., van den Berg, E., Ross, S., & de Grauw, J. (2020). Objective assessment of acute pain in foals using a facial expression-based pain scale. Animals, 10(9), [1610]. https://doi.org/10.3390/ani10091610
Stas, E., Kranenburg, L., Witt, P., de Grauw, J., van den Brand, J., Ensink, J., & Brommer, H. (2020). An atypical presentation of a mesenteric Meckel's diverticulum in a 7-year-old warmblood mare: case report. BMC Veterinary Research, 16(1), [409]. https://doi.org/10.1186/s12917-020-02631-w
Van den Brom, R., Greijdanus-van der Putten, S., Van der Heijden, M., Lievaart-Peterson, K., Vellema, P., & De Grauw, J. (2020). Thermal disbudding in goat kids in the Netherlands: Current practice, complications and considerations. Small Ruminant Research, 183, 1-5. [106036]. https://doi.org/10.1016/j.smallrumres.2019.106036
Diloksumpan, P., Bolaños, R. V., Cokelaere, S., Pouran, B., de Grauw, J., van Rijen, M., van Weeren, R., Levato, R., & Malda, J. (2020). Orthotopic Bone Regeneration within 3D Printed Bioceramic Scaffolds with Region-Dependent Porosity Gradients in an Equine Model. Advanced healthcare materials, 9(10), 1-11. [e1901807]. https://doi.org/10.1002/adhm.201901807
Bolaños, R. V., Castilho, M., de Grauw, J., Cokelaere, S., Plomp, S., Groll, J., van Weeren, P. R., Gbureck, U., & Malda, J. (2020). Long-Term in Vivo Performance of Low-Temperature 3D-Printed Bioceramics in an Equine Model. ACS Biomaterials Science and Engineering, 6(3), 1681-1689. https://doi.org/10.1021/acsbiomaterials.9b01819
2019
Wetenschappelijke publicaties
De Grauw, J., & Van Loon, T. (2019). Successful treatment of prolonged postoperative ileus following resection of a small intestinal spindle cell sarcoma in a horse. Veterinary Record Case Reports, 7(3), [e000899]. https://doi.org/10.1136/vetreccr-2019-000899
Boere, J., van de Lest, C. H. A., de Grauw, J. C., Plomp, S. G. M., Libregts, S. F. W. M., Arkesteijn, G. J. A., Malda, J., Wauben, M. H. M., & van Weeren, P. R. (2019). Extracellular vesicles in synovial fluid from juvenile horses: No age-related changes in the quantitative profile. Veterinary Journal, 244, 91-93. https://doi.org/10.1016/j.tvjl.2018.12.010
2018
Wetenschappelijke publicaties
de Grauw, J. C., van Loon, J. P. A. M., & van Oostrom, H. (2018). Comparison of different methods to calculate venous admixture in anaesthetized horses. Veterinary Anaesthesia and Analgesia, 45(5), 640-647. https://doi.org/10.1016/j.vaa.2018.02.010
2016
Wetenschappelijke publicaties
Frisbie, D. D., McIlwraith, C. W., & de Grauw, J. C. (2016). Synovial fluid and serum biomarkers. In C. W. McIlwraith, D. D. Frisbie, C. W. Kawcak, & P. R. van Weeren (Eds.), Joint disease in the horse (2 ed., pp. 179-191). Elsevier.
de Grauw, J. C., Visser-Meijer, M. C., Lashley, F., Meeus, P., & van Weeren, P. R. (2016). Intra-articular treatment with triamcinolone compared with triamcinolone with hyaluronate: A randomised open-label multicentre clinical trial in 80 lame horses. Equine Veterinary Journal, 48(2), 152-158. https://doi.org/10.1111/evj.12383
de Grauw, J. C., & van Loon, J. P. A. M. (2016). Systematic pain assessment in horses. Veterinary Journal, 209, 14-22. https://doi.org/10.1016/j.tvjl.2015.07.030
2015
Wetenschappelijke publicaties
de Grauw, J. C. (2015). Analgesia for critical patients: Where internal medicine and anesthesiology meet. In ECEIM annual conference
Visser, J., Levett, P. A., te Moller, N. C. R., Besems, J., Boere, K. W. M., van Rijen, M. H. P., de Grauw, J. C., Dhert, W. J. A., van Weeren, P. R., & Malda, J. (2015). Crosslinkable Hydrogels Derived from Cartilage, Meniscus, and Tendon Tissue. Tissue Engineering. Part A, 21(7-8), 1195-1206. https://doi.org/10.1089/ten.tea.2014.0362
Petit, A., Redout, E. M., van de Lest, C. H., de Grauw, J. C., Müller, B., Meyboom, R., van Midwoud, P., Vermonden, T., Hennink, W. E., & van Weeren, R. (2015). Sustained intra-articular release of celecoxib from in situ forming gels made of acetyl-capped PCLA-PEG-PCLA triblock copolymers in horses. Biomaterials, 53, 426-436. https://doi.org/10.1016/j.biomaterials.2015.02.109
Overige resultaten
Boere, J., van de Lest, C. H. A., de Grauw, J. C., Libregts, S. F. W. M., Arkesteijn, G., Bergman, J., Geerts, W. J., Malda, J., Wauben, M. H. M., & René van Weeren, P. (2015). Quantitative and qualitative analysis of synovial fluid extracellular vesicles in an equine model for acute synovitis. Abstract from Veterinary Science Day, Bunnik, Netherlands.
Boere, J., van de Lest, C. H. A., de Grauw, J. C., Malda, J., van Weeren, P. R., & Wauben, M. H. M. (2015). High-resolution flow cytometric analysis of synovial fluid derived extracellular vesicle populations during joint inflammation. Abstract from ISEV annual meeting 2015, Washington, DC, United States.
2014
Wetenschappelijke publicaties
Higler, M. H., Brommer, H., L'Ami, J. J., de Grauw, J. C., Nielen, M., van Weeren, P. R., Laverty, S., Barneveld, A., & Back, W. (2014). The effects of three-month oral supplementation with a nutraceutical and exercise on the locomotor pattern of aged horses. Equine Veterinary Journal, 46(5), 611-617. https://doi.org/10.1111/evj.12182
de Grauw, J. C., van Loon, J. P. A. M., van de Lest, C. H. A., Brunott, A., & van Weeren, P. R. (2014). In vivo effects of phenylbutazone on inflammation and cartilage-derived biomarkers in equine joints with acute synovitis. Veterinary Journal, 201(1), 51-56. https://doi.org/10.1016/j.tvjl.2014.03.030
Overige resultaten
van Sommeren, A., lamoré, M., Elte, Y., de Grauw, J., de Graaf - Roelfsema, E., & Back, W. (2014). An assessment of equine laminitic patients admitted to a university ambulatory clinic: predisposing field fac tors and underlying endocrinological disorders (2003 - 2013).. Abstract from Voorjaarsdagen 2014, Amsterdam.
Boere, J., de Grauw, J., van de Lest, C., Malda, J., Wauben, M., & van Weeren, R. (2014). Increased concentration of extracellular vesicles in the synovial fluid during synovitis LPS-induced inflammation in the joint. Abstract from Dutch Society for Matrix Biology (NVMB) Symposium, Amersfoort, Netherlands.
Boere, J., van de Lest, C., Nolte - t Hoen, E., Libregts, S., Wubbolts, R., de Grauw, J., Malda, J., Wauben, M., & van Weeren, R. (2014). Cartilage homeostasis might be regulated by extracellular vesicles facilitating intercellular communication between joint cells (3). Abstract from NIRM consortium meeting, Rotterdam, Netherlands.
Boere, J., van de Lest, C., Nolte - t Hoen, E., Libregts, S., Wubbolts, R., de Grauw, J., Malda, J., Wauben, M., & van Weeren, R. (2014). Cartilage homeostasis might be regulated by extracellular vesicles facilitating intercellular communication between joint cells (2). Abstract from FEBS workshop: Lipids as Molecular Switches, Island of Spetses, Greece.
Boere, J., van de Lest, C., Nolte - t Hoen, E., Libregts, S., Wubbolts, R., de Grauw, J., Malda, J., Wauben, M., & van Weeren, R. (2014). Cartilage homeostasis might be regulated by extracellular vesicles facilitating intercellular communication between joint cells. Abstract from 1st Matrix Biology Europe (MBE) conference (XXIVth FECTS meeting), Rotterdam, Netherlands.
Boere, J., van de Lest, C., Nolte - t Hoen, E., Libregts, S., Wubbolts, R., de Grauw, J., Malda, J., Wauben, M., & van Weeren, R. (2014). Extracellular vesicles isolated from equine synovial fluid bind to and are internalized by chondrocytes and synoviocytes in vitro. Abstract from International Society for Extracellular Vesicles (ISEV) Annual Meeting, Rotterdam, Netherlands.
van Weeren, R., de Grauw, J., van de Lest, C., Boere, J., & Redout, E. (2014). New research in equine synovial fluid biomarkers. Abstract from Havemeyer Meeting on Biomarkers, Steamboat Springs, CO, United States.
2013
Wetenschappelijke publicaties
Heinola, T., de Grauw, J. C., Virkki, L., Kontinen, A., Raulo, S. M., Sukura, A., & Konttinen, Y. T. (2013). Bovine chronic osteoarthritis causes minimal change in synovial fluid. Journal of Comparative Pathology, 148(4), 335-44. https://doi.org/10.1016/j.jcpa.2012.08.001
van Loon, J. P. A. M., de Grauw, J. C., Brunott, A., Weerts, E. A. W. S., & van Weeren, P. R. (2013). Upregulation of articular synovial membrane μ-opioid-like receptors in an acute equine synovitis model. Veterinary Journal, 196(1), 40-46. https://doi.org/10.1016/j.tvjl.2012.07.030
Malda, J., de Grauw, J. C., Benders, K. E. M., Kik, M. J. L., van de Lest, C. H. A., Creemers, L. B., Dhert, W. J. A., & van Weeren, P. R. (2013). Of mice, men and elephants: the relation between articular cartilage thickness and body mass. PLoS One, 8(2), e57683. http://www.ncbi.nlm.nih.gov/pubmed/23437402
Overige resultaten
Visser, J., Levett, P. A., Te Moller, N. C. R., Besems, J., de Grauw, J. C., van Weeren, P. R., Dhert, W. J. A., & Malda, J. (2013). Arthroscopic optical coherence tomography provides detailed information on articular cartilage lesions in horses.. Abstract from Ann. Meet. Dutch Soc. Matriox Biol., Lunteren, May 2013..
Boere, J., van de Lest, C. H. A., de Grauw, J. C., Wauben, M. H. M., Malda, J., & van Weeren, P. R. (2013). Intercellular communication in the equine joint: lipidome analysis of cell-derived vesicles. Abstract from Dutch Society for Biomaterials and Tissue Engineering (NBTE) Annual Meeting, Lunteren, Netherlands.
Boere, J., van de Lest, C. H. A., de Grauw, J. C., Wauben, M. H. M., Malda, J., & van Weeren, P. R. (2013). Lipidome analysis of cell-derived vesicles in the equine joint. Abstract from Veterinary Science Day November 14th.
2012
Wetenschappelijke publicaties
Malda, J., Benders, K. E. M., Klein, T. J., de Grauw, J. C., Kik, M. J. L., Hutmacher, D. W., Saris, D. B. F., van Weeren, P. R., & Dhert, W. J. A. (2012). Comparative study of depth-dependent characteristics of equine and human osteochondral tissue from the medial and lateral femoral condyles. Osteoarthritis and Cartilage, 20(10), 1147-1151. https://doi.org/10.1016/j.joca.2012.06.005
Overige resultaten
Boere, J., van de Lest, C., Redout, E., de Grauw, J., Malda, J., & van Weeren, R. (2012). Similar effects of interleukin-1beta on cartilage explant cultures in media supplemented with adult serum, adult synovial fluid or immature serum. Abstract from 21st Ann. Meet. Dutch Society for Biomaterials and Tissue Engineering (NBTE) (Lunteren The Netherlands).
2011
Wetenschappelijke publicaties
de Grauw, J. C., Donabédion, M., van de Lest, C. H. A., Perona, G., Robert, C., Lepage, O., Martin-Rosset, W., & van Weeren, P. R. (2011). Assessment of synovial fluid biomarkers in healthy foals and in foals with tarsocrural osteochondrosis. Veterinary Journal, dec 190(3), 390-395. https://doi.org/10.1016/j.tvjl.2010.12.001
de Grauw, J. C., van de Lest, C. H. A., & van Weeren, P. R. (2011). A targeted lipidomics approach to the study of eicosanoid release in synovial joints. Arthritis Research & Therapy, 13((4):R123), 1-30. https://doi.org/10.1186/ar3427
de Grauw, J. C. (2011). Molecular monitoring of equine joint homeostasis. Veterinary Quarterly, 31(2), 77-86. https://doi.org/10.1080/01652176.2011.565546
Overige resultaten
Benders, K. E. M., Klein, T. J., de Grauw, J. C., Hutmacher, D. W., van Weeren, P. R., Saris, D. B. F., Dhert, W. J. A., & Malda, J. (2011). Depth-dependent Similarities of Equine and Human Osteochondral Tissue from the Femoral Condyles. Abstract from UK Matrix Biology meeting, Bristol, UK.
2010
Wetenschappelijke publicaties
de Grauw, J. C., Heinola, T., van Weeren, R., Kiviranta, I., & Konttinen, Y. T. (2010). Rapid release of high mobility group box protein-1 (HMGB-1) in transient arthritis. Clinical and Experimental Rheumatology, 28(2), 292-3.
l'Ami, J. J., Higler, M. H., Brommer, H., de Grauw, J. C., & van Weeren, P. R. (2010). Kinematic evaluation of the effect of a 3-month oral glucosamine/chondroitin supplement on the locomotor pattern of a veteran horse population. In ECVS 2010 (pp. 79-80)
van Weeren, P. R., & de Grauw, J. C. (2010). Pain in osteoarthritis. Veterinary Clinics of North America-Equine Practice, 26, 619-642.
de Grauw, J. C. (2010). Molecular monitoring of equine joint homeostasis. Utrecht University.
https://dspace.library.uu.nl/bitstream/handle/1874/188215/Grauw.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/188215/Grauw.pdf?sequence=1
de Grauw, J. C., Heinola, T., van Weeren, P. R., Kiviranta, I., & Konttinen, Y. T. (2010). Rapid relaese of high mobility group box protein-1 (HMGB-1) in transient arthritis. Clinical and Experimental Rheumatology, 28(2), 292-293.
van Loon, J. P. A. M., de Grauw, J. C., van Dierendonck, M. C., l' Ami, J. J., Back, W., & van Weeren, P. R. (2010). Intra-articular opioid analgesia is effective in reducing pain and inflammation in an equine LPS induced synovitis model. Equine Veterinary Journal, 42(5), 412-419.
Overige resultaten
de Grauw, J. C., van Loon, J. P. A. M., van de Lest, C. H. A., & van Weeren, P. R. (Accepted/In press). The effects of IA morphine vs. saline injection on inflammation and cartilage turnover in equine joints with acute synovitis.. Abstract from The European Veterinary Conference Voorjaarsdagen.
de Grauw, J. C., van Loon, J. P. A. M., van de Lest, C. H. A., & van Weeren, P. R. (Accepted/In press). The effects of IA morphine vs. saline injection on synovial fluid biomarkers in equine joints with acute synovitis.. Abstract from the 56th annual conference of the Orthopaedic Research Society..
de Grauw, J. C., Bastiaansen-Jenniskens, Y., van de Lest, C. H. A., van Osch, G., & van Weeren, P. R. (Accepted/In press). The effects of lipoxin A4 on il-1b induced catabolic changes in equine articular cartilage.. Abstract from Annual conference of the dutch society for matrix biology..
de Grauw, J. C., Donabédian, M., van de Lest, C. H. A., Perona, G., Robert, C., Lepage, O., Martin-Rosset, W., & van Weeren, P. R. (Accepted/In press). Longitudinal monitoring of synovial fluid biomarkers over the first year of life in foals that do or do not go on to develop tarsocrural osteochondrosis.. 94-94. Abstract from British Equine Veterinary Association (BEVA 2010), Birmingham, United Kingdom.
2009
Wetenschappelijke publicaties
de Grauw, J. C., van de Lest, C. H. A., & van Weeren, P. R. (2009). Inflammatory mediators and cartilage biomarkers in synovial fluid after a single inflammatory insult: a longitudinal experimental study. Arthritis Research & Therapy, 11, R35.
https://dspace.library.uu.nl/bitstream/handle/1874/39575/Inflammatory%2520mediators%2520and%2520cartilage%2520biomarkers%2520in%2520synovial%2520fluid%2520after.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/39575/Inflammatory%2520mediators%2520and%2520cartilage%2520biomarkers%2520in%2520synovial%2520fluid%2520after.pdf?sequence=1
de Grauw, J. C., van de Lest, C. H. A., Brama, P. A. J., Rambags, B. P. B., & van Weeren, P. R. (2009). In vivo effects of meloxicam on inflammatory mediators, mmp activity and cartilage biomarkers in equine joints with acute synovitis. Equine Veterinary Journal, 41(7), 693-699.
Vakpublicaties
de Grauw, J., Brommer, H., & van Weeren, R. (2009). Gewrichtsaandoeningen, bewegen is leven. Paard en Sport, 2-5.
2008
Vakpublicaties
de Grauw, J. C., & Lipman, L. J. A. (2008). Fenylbutazon, het zwarte 'paard' in de NSAID-familie? Tijdschrift voor Diergeneeskunde, 133(6), 232-235.
2007
Wetenschappelijke publicaties
Brama, P. A. J., de Grauw, J. C., Brommer, H., & van Weeren, P. R. (2007). Cartilage degeneration in fetlock osteoarthritis - what have we learned? In M. Schramme, H. Tremaine, J. Walmsley, & J. Houlton (Eds.), 16th Annual Scientific Meeting European College of Veterinary Surgeons. (pp. 123-129).
2006
Wetenschappelijke publicaties
de Grauw, J. C., Brama, P. A., Wiemer, P., Brommer, H., van de Lest, C. H., & van Weeren, P. R. (2006). Cartilage-derived biomarkers and lipid mediators of inflammation in horses with osteochondritis dissecans of the distal intermediate ridge of the tibia. American Journal of Veterinary Research, 67(7), 1156-62. https://doi.org/10.2460/ajvr.67.7.1156
de Grauw, J. C., van de Lest, C. H. A., van Weeren, R., Brommer, H., & Brama, P. A. J. (2006). Arthrogenic lameness of the fetlock: synovial fluid markers of inflammation and cartilage turnover in relation to clinical joint pain. Equine Veterinary Journal, 38(4), 305-11.
de Grauw, J. C., van de Lest, C. H. A., van Weeren, P. R., Brommer, H., & Brama, P. A. J. (2006). Arthrogenic lameness of the fetlock: synovial fluid markers of inflammation and cartilage turnover in relation to clinical joint pain. Equine Veterinary Journal, 38(4), 305-311.