Dr. H.D. (Harold) Mac Gillavry

Dr. H.D. (Harold) Mac Gillavry

Universitair hoofddocent
Cell Biology, Neurobiology and Biophysics
h.d.macgillavry@uu.nl

Publicaties

2022

Wetenschappelijke publicaties

Indonesia Schizophrenia Consortium, Mac Gillavry, H., & de Jong, A. (2022). Mapping genomic loci implicates genes and synaptic biology in schizophrenia. Nature, 604, 502-508. https://doi.org/10.1038/s41586-022-04434-5
Bodzęta, A., Berger, F., & MacGillavry, H. D. (2022). Subsynaptic mobility of presynaptic mGluR types is differentially regulated by intra- and extracellular interactions. Molecular Biology of the Cell, 33(8), [ar66]. https://doi.org/10.1091/mbc.E21-10-0484
Willems, J., Westra, M., & MacGillavry, H. D. (2022). Single-Molecule Localization Microscopy of Subcellular Protein Distribution in Neurons. In Fluorescent Microscopy (pp. 271-288). (Methods in Molecular Biology). Humana Press. https://doi.org/10.1007/978-1-0716-2051-9_16
Westra, M., & MacGillavry, H. D. (2022). Precise Detection and Visualization of Nanoscale Temporal Confinement in Single-Molecule Tracking Analysis. Membranes, 12(7), [650]. https://doi.org/10.3390/membranes12070650
Catsburg, L., Westra, M., van Schaik, A. M., & MacGillavry, H. D. (2022). Dynamics and nanoscale organization of the postsynaptic endocytic zone at excitatory synapses. eLife, 11. https://doi.org/10.7554/eLife.74387
Droogers, W. J., Willems, J., MacGillavry, H. D., & de Jong, A. P. H. (2022). Duplex Labeling and Manipulation of Neuronal Proteins Using Sequential CRISPR/Cas9 Gene Editing. eNeuro, 9(4). https://doi.org/10.1523/ENEURO.0056-22.2022
Willems, J., & Mac Gillavry, H. (2022). A coordinate-based co-localization index to quantify and visualize spatial associations in single-molecule localization microscopy. Scientific Reports, 12, [4676]. https://doi.org/https://www.nature.com/articles/s41598-022-08746-4, https://doi.org/10.1038/s41598-022-08746-4
Shukla, R., Lavore, F., Maity, S., Derks, M. G. N., Jones, C. R., Vermeulen, B. J. A., Melcrová, A., Morris, M. A., Becker, L. M., Wang, X., Kumar, R., Medeiros-Silva, J., van Beekveld, R. A. M., Bonvin, A. M. J. J., Lorent, J. H., Lelli, M., Nowick, J. S., MacGillavry, H. D., Peoples, A. J., ... Weingarth, M. (2022). Teixobactin kills bacteria by a two-pronged attack on the cell envelope. Nature, 608(7922), 390-396. https://doi.org/10.1038/s41586-022-05019-y

2021

Wetenschappelijke publicaties

Westra, M., Gutierrez, Y., & MacGillavry, H. D. (2021). Contribution of Membrane Lipids to Postsynaptic Protein Organization. Frontiers in Synaptic Neuroscience, 13, 1-14. [790773]. https://doi.org/10.3389/fnsyn.2021.790773
Bodzęta, A., Scheefhals, N., & MacGillavry, H. D. (2021). Membrane trafficking and positioning of mGluRs at presynaptic and postsynaptic sites of excitatory synapses. Neuropharmacology, 200, 1-17. [108799]. https://doi.org/10.1016/j.neuropharm.2021.108799
Bodzeta, A., Berger, F., & MacGillavry, H. D. (2021). Subsynaptic mobility of presynaptic mGluR types is differentially regulated by intra- and extracellular interactions. (pp. 1-60). bioRxiv. https://doi.org/10.1101/2020.07.06.188995
https://dspace.library.uu.nl/bitstream/handle/1874/415162/2020.07.06.188995v2.full.pdf?sequence=1
Lindhout, F. W., Portegies, S., Kooistra, R., Herstel, L. J., Stucchi, R., Hummel, J. J. A., Scheefhals, N., Katrukha, E. A., Altelaar, M., MacGillavry, H. D., Wierenga, C. J., & Hoogenraad, C. C. (2021). Centrosome-mediated microtubule remodeling during axon formation in human iPSC-derived neurons. EMBO Journal, 40(10), 1-17. [e106798]. https://doi.org/10.15252/embj.2020106798

2020

Wetenschappelijke publicaties

van Gelder, C. A. G. H., Penning, R., Veth, T. S., Catsburg, L. A. E., Hoogenraad, C. C., MacGillavry, H. D., & Altelaar, M. (2020). Temporal Quantitative Proteomics of mGluR-induced Protein Translation and Phosphorylation in Neurons. Molecular and Cellular Proteomics, 19(12), 1952-1967. https://doi.org/10.1074/mcp.RA120.002199
Lindhout, F. W., Kooistra, R., Portegies, S., Herstel, L. J., Stucchi, R., Snoek, B. L., Altelaar, M., MacGillavry, H. D., Wierenga, C. J., & Hoogenraad, C. C. (2020). Quantitative mapping of transcriptome and proteome dynamics during polarization of human iPSC-derived neurons. eLife, 9. https://doi.org/10.7554/eLife.58124
Willems, J., de Jong, A. P. H., Scheefhals, N., Mertens, E., Catsburg, L. A. E., Poorthuis, R. B., de Winter, F., Verhaagen, J., Meye, F. J., & MacGillavry, H. D. (2020). ORANGE: A CRISPR/Cas9-based genome editing toolbox for epitope tagging of endogenous proteins in neurons. PLoS Biology, 18(4), [e3000665]. https://doi.org/10.1371/journal.pbio.3000665
Cao, Y., Lipka, J., Stucchi, R., Burute, M., Pan, X., Portegies, S., Tas, R., Willems, J., Will, L., MacGillavry, H., Altelaar, M., Kapitein, L. C., Harterink, M., & Hoogenraad, C. C. (2020). Microtubule Minus-End Binding Protein CAMSAP2 and Kinesin-14 Motor KIFC3 Control Dendritic Microtubule Organization. Current Biology, 30(5), 899-908.e6. https://doi.org/10.1016/j.cub.2019.12.056

2019

Wetenschappelijke publicaties

Berdenis Van Berlekom, A., Muflihah, C. H., Snijders, G. J. L. J., Macgillavry, H. D., Middeldorp, J., Hol, E. M., Kahn, R. S., & De Witte, L. D. (2019). Synapse Pathology in Schizophrenia: A Meta-analysis of Postsynaptic Elements in Postmortem Brain Studies. Schizophrenia Bulletin, [sbz060]. https://doi.org/10.1093/schbul/sbz060
Scheefhals, N., Catsburg, L. A. E., Westerveld, M. L., Blanpied, T. A., Hoogenraad, C. C., & Macgillavry, H. D. (2019). Shank Proteins Couple the Endocytic Zone to the Postsynaptic Density to Control Trafficking and Signaling of Metabotropic Glutamate Receptor 5. Cell Reports, 29(2), 258-269, e8. https://doi.org/10.1016/j.celrep.2019.08.102
Lindhout, F. W., Cao, Y., Kevenaar, J. T., Bodzęta, A., Stucchi, R., Boumpoutsari, M. M., Katrukha, E. A., Altelaar, M., MacGillavry, H. D., & Hoogenraad, C. C. (2019). VAP-SCRN1 interaction regulates dynamic endoplasmic reticulum remodeling and presynaptic function. EMBO Journal, 38(20), [e101345]. https://doi.org/10.15252/embj.2018101345
Koopmans, F., van Nierop, P., Andres-Alonso, M., Byrnes, A., Cijsouw, T., Coba, M. P., Cornelisse, L. N., Farrell, R. J., Goldschmidt, H. L., Howrigan, D. P., Hussain, N. K., Imig, C., de Jong, A. P. H., Jung, H., Kohansalnodehi, M., Kramarz, B., Lipstein, N., Lovering, R. C., MacGillavry, H., ... Verhage, M. (2019). SynGO: An Evidence-Based, Expert-Curated Knowledge Base for the Synapse. Neuron, 103(2), 217-234. https://doi.org/10.1016/j.neuron.2019.05.002

2018

Wetenschappelijke publicaties

MacGillavry, H. D., & Hoogenraad, C. C. (2018). Membrane trafficking and cytoskeletal dynamics in neuronal function. Molecular and Cellular Neurosciences, 91, 1-2. https://doi.org/10.1016/j.mcn.2018.08.003
Scheefhals, N., & MacGillavry, H. D. (2018). Functional organization of postsynaptic glutamate receptors. Molecular and Cellular Neurosciences, 91, 82-94. https://doi.org/10.1016/j.mcn.2018.05.002

2017

Wetenschappelijke publicaties

Post, H., Penning, R., Fitzpatrick, M., Garrigues, L. B., Wu, W., Mac Gillavry, H. D., Hoogenraad, C. C., Heck, A. J. R., & Altelaar, A. F. M. (2017). Robust, Sensitive, and Automated Phosphopeptide Enrichment Optimized for Low Sample Amounts Applied to Primary Hippocampal Neurons. Journal of Proteome Research, 16(2), 728-737. https://doi.org/10.1021/acs.jproteome.6b00753
https://dspace.library.uu.nl/bitstream/handle/1874/359699/10.1021acs.jproteome.6b00753_Post_et_al._2017.pdf?sequence=3

2016

Wetenschappelijke publicaties

Tang, AH., Chen, H., Li, TP., Metzbower, SR., Mac Gillavry, H. D., & Blanpied, TA. (2016). A trans-synaptic nanocolumn aligns neurotransmitter release to receptors. Nature, 536, 210-214. https://doi.org/10.1038/nature19058
Li, TP., Song, Y., Mac Gillavry, H. D., Blanpied, TA., & Raghavachari, S. (2016). Protein Crowding within the Postsynaptic Density Can Impede the Escape of Membrane Proteins. Journal of Neuroscience, 36(15), 4276-4295. https://doi.org/10.1523/JNEUROSCI.3154-15.2016
Mac Gillavry, H. D., Kerr, JM., Kassner, J., Frost, NA., & Blanpied, TA. (2016). Shank-cortactin interactions control actin dynamics to maintain flexibility of neuronal spines and synapses. European Journal of Neuroscience, 43(2), 179-193. https://doi.org/10.1111/ejn.13129

2014

Overige resultaten

Mac Gillavry, H., Kerr, J., Frost, N., & Blanpied, T. (2014). Triple miRNA Shank knockdown shows that Shank-cortactin interactions control actin dynamics. Poster session presented at 44th Annual Meeting of the Society for Neuroscience, Washington DC, United States.