dr. E.G. (Eric G.) Huizinga
Gegenereerd op 2018-09-22 13:51:23

Betrokken bij de opleiding(en)
Gegenereerd op 2018-09-22 13:51:23
Alle publicaties
  2017 - Wetenschappelijke publicaties
Bakkers, Mark J G, Lang, Yifei, Feitsma, Louris J, Hulswit, Ruben J G, de Poot, Stefanie A H, van Vliet, Arno L W, Margine, Irina, de Groot-Mijnes, Jolanda D F, van Kuppeveld, Frank J M, Langereis, Martijn A, Huizinga, Eric G & de Groot, Raoul J (08-03-2017). Betacoronavirus Adaptation to Humans Involved Progressive Loss of Hemagglutinin-Esterase Lectin Activity. Cell Host and Microbe, 21 (3), (pp. 356-366) (11 p.). Copyright © 2017 Elsevier Inc. All rights reserved..
Sivapalaratnam, Suthesh, Westbury, Sarah K., Stephens, Jonathan C., Greene, Daniel, Downes, Kate, Kelly, Anne M., Lentaigne, Claire, Astle, William J., Huizinga, Eric G., Nurden, Paquita, Papadia, Sofia, Peerlinck, Kathelijne, Penkett, Christopher J., Perry, David J., Roughley, Catherine, Simeoni, Ilenia, Stirrups, Kathleen E, Hart, Daniel P., Tait, R. Campbell, Mumford, Andrew D., Laffan, Michael A., Freson, Kathleen, Ouwehand, Willem H., Kunishima, Shinji & Turro, Ernest (26-01-2017). Rare variants in GP1BB are responsible for autosomal dominant macrothrombocytopenia. Blood, 129 (4), (pp. 520-524).
  2016 - Wetenschappelijke publicaties
Bakkers, Mark J G, Zeng, Qinghong, Feitsma, Louris J, Hulswit, Ruben J G, Li, Zeshi, Westerbeke, Aniek, van Kuppeveld, Frank J M, Boons, Geert-Jan, Langereis, Martijn A, Huizinga, Eric G & de Groot, Raoul J (31-05-2016). Coronavirus receptor switch explained from the stereochemistry of protein-carbohydrate interactions and a single mutation. Proceedings of the National Academy of Sciences of the United States of America, 113 (22), (pp. E3111-E3119).
  2015 - Wetenschappelijke publicaties
Langereis, Martijn A, Bakkers, Mark J G, Deng, Lingquan, Padler-Karavani, Vered, Vervoort, Stephin J, Hulswit, Ruben J G, van Vliet, Arno L W, Gerwig, Gerrit J, de Poot, Stefanie A H, Boot, Willemijn, van Ederen, Anne Marie, Heesters, Balthasar A, van der Loos, Chris M, van Kuppeveld, Frank J M, Yu, Hai, Huizinga, Eric G, Chen, Xi, Varki, Ajit, Kamerling, Johannis P & de Groot, Raoul J (18-06-2015). Complexity and Diversity of the Mammalian Sialome Revealed by Nidovirus Virolectins. Cell Reports Copyright © 2015 The Authors. Published by Elsevier Inc. All rights reserved..
Diebolder, Christoph A, Halff, Els F, Koster, Abraham J, Huizinga, Eric G & Koning, Roman I (01-12-2015). Cryoelectron Tomography of the NAIP5/NLRC4 Inflammasome - Implications for NLR Activation. Structure with Folding & design, 23 (12), (pp. 2349-57) (9 p.). Copyright © 2015 Elsevier Ltd. All rights reserved..
Koymans, Kirsten J, Feitsma, Louris J, Brondijk, T Harma C, Aerts, Piet C, Lukkien, Eddie, Lössl, Philip, van Kessel, Kok P M, de Haas, Carla J C, van Strijp, Jos A G & Huizinga, Eric G (01-09-2015). Structural basis for inhibition of TLR2 by staphylococcal superantigen-like protein 3 (SSL3). Proceedings of the National Academy of Sciences of the United States of America, 112 (35), (pp. 11018-23) (6 p.).
  2014 - Wetenschappelijke publicaties
Volokina, E., Jakobi, A.J., Urbanus, R.T, Huizinga, E.G., Sluiter, H., Middel, C., Westra, D., van Heerde, W.L., van de Kar, N. & van den Heuvel, L. (2014). Novel sequence variation affects GPIb α in post-diarrheal hemolytic uremic syndrome. Journal of nephrology & therapeutics, S11 (5 p.).
Halff, Els F., Versteeg, Marian, Brondijk, T. Harma C & Huizinga, Eric G. (01-01-2014). When less becomes more - Optimization of protein expression in HEK293-EBNA1 cells using plasmid titration - A case study for NLRs. Protein Expression and Purification, 99, (pp. 27-34) (8 p.).
  2013 - Wetenschappelijke publicaties
Karper, J.C., Ewing, M.M., de Vries, M.R., de Jager, S.C.A., Peters, E.A.B., de Boer, H.C., van Zonneveld, A.J., Kuiper, J., Huizinga, E.G., Brondijk, T.H.C., Jukema, J.W. & Quax, P.H.A. (2013). TLR accessory molecule RP105 (CD180) is involved in post-interventional vascular remodeling and soluble RP105 modulates neointima formation. PLoS One, 8 (7), (pp. 1-9) (9 p.).
  2012 - Wetenschappelijke publicaties
Jakobi, A.J. & Huizinga, E.G. (2012). A rapid cloning method employing orthogonal end protection. PLoS One, 7 (6), (pp. 1-9) (9 p.).
Bardoel, B.W., de Vos, R., Bouman, T., Aerts, P.C., Bestebroer, J., Huizinga, E.G., Brondijk, T.H.C., van Strijp, J.A.G. & de Gosselaar - de Haas, C.J.C. (2012). Evasion of Toll-like receptor 2 activation by staphylococcal superantigen-like protein 3. Journal of Molecular Medicine, 90 (10), (pp. 1109-1120) (11 p.).
Halff, Els F., Diebolder, Christoph A., Versteeg, Marian, Schouten, Arie, Brondijk, T. Harma C. & Huizinga, Eric G. (09-11-2012). Formation and structure of a NAIP5-NLRC4 inflammasome induced by direct interactions with conserved N- and C-terminal regions of flagellin. Journal of Biological Chemistry, 287 (46), (pp. 38460-38472) (13 p.).
Brondijk, T.H.C., Bihan, D., Farndale, R.W. & Huizinga, E.G. (2012). Implications for collagen I chain registry from the structure of the collagen von Willebrand factor A3 domain complex. Proceedings of the National Academy of Sciences of the United States of America, 109 (14), (pp. 5353-5258) (6 p.).
Volokhina, E.B., Jakobi, A.J., Huizinga, E.G., Sluiter, H.E., Middel, C., Westra, D., Van Heerde, W.L., Van De Kar, N.C.A.J. & Van Den Heuvel, L.P. (01-07-2012). Novel sequence variation affects GPIbα in typical HUS patient. Zoonoses and Public Health, 59, (pp. 55) (1 p.).
Langereis, M.A., Zeng, Q., Heesters, B., Huizinga, E.G. & de Groot, R.J. (2012). The murine coronavirus hemagglutinin-esterase receptor-binding site: a major shift in ligand specificity through modest changes in architecture. PLoS Pathogens, 8 (1), (pp. 1-8) (8 p.).
  2011 - Wetenschappelijke publicaties
Jakobi, A.J., Mashaghi, A., Tans, S.J. & Huizinga, E.G. (2011). Calcium modulates force sensing by the von Willebrand factor A2 domain. Nature Communications, 2:385, (pp. 1-9) (9 p.).
  2010 - Wetenschappelijke publicaties
Brondijk, T.H.C., de Ruiter, T., Ballering, J., Wienk, H., Lebbink, R.J., van Ingen, H., Boelens, R., Farndale, R.W., Meyaard, L. & Huizinga, E.G. (2010). Crystal structure and collagen-binding site of immune inhibitory receptor LAIR-1: unexpected implications for collagen binding by platelet receptor GPVI. Blood, 115 (7), (pp. 1364-1373) (10 p.).
van Wijk, R., Sutherland, S., van Wesel, A.C.W., Huizinga, E.G., Percy, M.J., Bierings, M.B. & Lee, F.S. (2010). Erythrocytosis associated with a novel missense mutation in the HIF2A gene. Haematologica, 95 (5), (pp. 829-832) (4 p.).
  2009 - Wetenschappelijke publicaties
van Wijk, H.A., Huizinga, E.G., van Wesel, A.C.W., van Oirschot - Hermans, B.A., Hadders, M.A. & van Solinge, W.W. (2009). Fifteen novel mutations in PKLR associated with pyruvate kinase (PK) deficiency. Structural implications of amino acid substitutions in PK. Human Mutation, 30, (pp. 446-453) (8 p.).
Langereis, M.A., Zeng, Q., Gerwig, G.J., Frey, B., von Itzstein, M., Kamerling, J.P., de Groot, R.J. & Huizinga, E.G. (2009). Structural basis for ligand and substrate recognition by torovirus hemagglutinin esterases. Proceedings of the National Academy of Sciences of the United States of America, 106 (37), (pp. 15897-15902) (6 p.).
  2008 - Wetenschappelijke publicaties
Marx, P.F., Brondijk, T.H.C., Plug, T., Romijn, R.A., Hemrika, W., Meijers, J.C.M. & Huizinga, E.G. (2008). Crystal structures of TAFI elucidate the inactivation mechanism of activated TAFI: a novel mechanism for enzyme autoregulation. Blood, 112, (pp. 2803-2809) (7 p.).
Zeng, Q., Langereis, M.A., van Vliet, A.L., Huizinga, E.G. & de Groot, R.J. (2008). Structure of coronavirus hemagglutinin-esterase offers insight into corona and influenza virus evolution. Proceedings of the National Academy of Sciences of the United States of America, 105 (26), (pp. 9065-9069) (5 p.).
  2007 - Wetenschappelijke publicaties
Milder, F.J., Gomes, L., Schouten, A., Janssen, B.J.C., Huizinga, E.G., Romijn, R.A., Hemrika, W., Roos, A, Daha, M.R. & Gros, P. (2007). Factor B structure provides insights into activation of the central protease of the complement system. Nature Structural and Molecular Biology, 14, (pp. 224-228) (5 p.).
  2006 - Wetenschappelijke publicaties
Lisman, T., Raynal, N., Groeneveld, D., Maddox, B., Peachey, A.R., Huizinga, E.G., de Groot, Ph.G. & Farndale, R.W. (2006). A single high-affinity binding site for von Willebrand factor in collagen III, identified using synthetic triple-helical peptides. Blood, 108, (pp. 3753-3756) (4 p.).
Obert, B., Romijn, R.A.P., Houllier, A., Huizinga, E.G. & Girma, J.P. (2006). Characterization of bitiscetin-2, a second form of bitiscetin from the venom of Bitis Arietans: comparison of its binding site with the collagen-binding site on the von Willebrand Factor A3-domain. Journal of Thrombosis and Haemostasis, 4, (pp. 1596-1601) (6 p.).
Staelens, S., Hadders, M.A., Vauterin, S., Platteau, C., De Maeyer, M., Vanhoorelbeke, K., Huizinga, E.G. & Deckmyn, H. (2006). Paratope Determination of the Antithrombotic Antibody 82D6A3 Based on the Crystal Structure of Its Complex with the von Willebrand Factor A3-Domain. Journal of Biological Chemistry, 281 (4), (pp. 2225-2231) (7 p.).
Milder, F.J., Raaijmakers, H.C.A., Vandeputte, D.A.A., Schouten, A., Huizinga, E.G., Romijn, R.A., Hemrika, W., Roos, A, Daha, M.R. & Gros, P. (2006). Structure of complement component C2a: implications for convertase formation and substrate binding. Structure with Folding & design, 14 (10), (pp. 1587-1597) (11 p.).
  2005 - Wetenschappelijke publicaties
Janssen, B.J.C., Huizinga, E.G., Raaijmakers, H.C.A., Roos, A, Daha, M.R., Nilsson-Ekdahl, K., Nilsson, B. & Gros, P. (2005). Structures of complement component C3 provide insights into the function and evolution of immunity. Nature, 437, (pp. 505-511) (7 p.).
  2004 - Wetenschappelijke publicaties
Lenting, P.J., Westein, E., Terraube, V., Ribba, A.-S., Huizinga, E.G., Meyer, D., de Groot, P.G. & Denis, C.V. (2004). An experimental model to study in vivo survival of Von Willebrand factor - Basic aspects and application to the R1205H mutation. Journal of Biological Chemistry, 279, (pp. 12102-12109) (8 p.).
van Wijk, R., Huizinga, E.G., Prins, I., Kors, W.A., Rijksen, G., Bierings, M.B. & van Solinge, W.W. (2004). Distinct phenotypic expression of two de novo missense mutations affecting the dimer interface of glucose-6-phosphate. Blood Cells, Molecules, and Diseases, 32, (pp. 112-117) (6 p.).
Vanhoorelbeke, K., Ulrichts, H., Romijn, R.A.P., Huizinga, E.G. & Deckmyn, H. (2004). The GPlbα-thrombin interaction: far from crystal clear. Trends in Molecular Medicine, 10 (1), (pp. 33-39) (7 p.).
  2003 - Wetenschappelijke publicaties
Vanhoorelbeke, K., Depraetere, H., Romijn, R.A.P., Huizinga, E.G., Maeyeri, M.D. & Deckmyn, H. (2003). A Consensus Tetrapeptide Selected by Phage Display Adopts the Conformation of a Dominant Discontinuous Epitope of a Monoclonal Anti-VWF Antibody That Inhibits the von Willebrand Factor-Collagen Interaction. Journal of Biological Chemistry, 278 (39), (pp. 37815-37821) (7 p.).
van Wijk, H.A., Rijksen, G., Huizinga, E.G., Nieuwenhuis, H.K. & van Solinge, W.W. (2003). HK Utrecht: missense mutation in the active site of human hexokinase associated with hexokinase deficiency and severe nonspherocytic hemolytic anemia. Blood, 101, (pp. 345-347) (3 p.).
Romijn, R.A.P., Westein, E., Bouma, B., Schiphorst, M.E., Sixma, J.J., Lenting, P.J. & Huizinga, E.G. (2003). Mapping the collagen-binding site in the von Willebrand Factor-A3 domain. Journal of Biological Chemistry, 278 (17), (pp. 15035-15039) (5 p.).
Tsuji, S. & Huizinga, E.G. (2003). Mechanism of the Glycoprotein Iba-von Willebrand Factor interaction based on crystal structure analysis. Japanese Journal of Thrombosis and Hemostasis, 14, (pp. 101-106) (6 p.).
  2002 - Wetenschappelijke publicaties
Oubrie, Arthur, Rozeboom, Henriëtte J., Kalk, Kor H., Huizinga, Eric G. & Dijkstra, Bauke W. (01-02-2002). Crystal structure of quinohemoprotein alcohol dehydrogenase from Comamonas testosteroni: Structural basis for substrate oxidation and electron transfer. Journal of Biological Chemistry, 277 (5), (pp. 3727-3732) (6 p.).
Huizinga, E.G., Tsuji, S., Romijn, R.A.P., Schiphorst, M.E., de Groot, P.G., Sixma, J.J. & Gros, P. (2002). Structures of glycoprotein Ibα and its complex with von Willebrand Factor A1 domain. Science, 297, (pp. 1176-1179) (4 p.).
  2001 - Wetenschappelijke publicaties
Oubrie, A., Huizinga, E.G., Rozeboom, H.J., Kalk, K.H., De Jong, G.A.H., Duine, J.A. & Dijkstra, B.W. (22-12-2001). Crystallization of quinohaemoprotein alcohol dehydrogenase from Comamonas testosteroni: Crystals with unique optical properties. Acta Crystallographica Section D: Biological Crystallography, 57 (11), (pp. 1732-1734) (3 p.).
Cauwenberghs, Nancy, Vanhoorelbeke, Karen, Vauterin, Stephan, Westra, Douwe F., Romo, Gabriel, Huizinga, Eric G., Lopez, José A., Berndt, Michael C., Harsfalvi, Jolàn & Deckmyn, Hans (01-08-2001). Epitope mapping of inhibitory antibodies against platelet glycoprotein Ibα reveals interaction between the leucine-rich repeat N-terminal and C-terminal flanking domains of glycoprotein Ibα. Blood, 98 (3), (pp. 652-660) (9 p.).
van Wijk, R., Nieuwenhuis, K., van den Berg, H.M., Huizinga, E.G., van der Meijden, B.B., Kraaijenhagen, R.J. & van Solinge, W.W. (2001). Five novel mutations in the gene for human blood coagulation factor V associated with type I factor V deficiency. Blood, 98 (2), (pp. 358-365) (8 p.).
Romijn, R.A.P., Bouma, B., Wuyster, W., Gros, P., Kroon, J., Sixma, J.J. & Huizinga, E.G. (2001). Identification of the collagen-binding site of the von Willebrand Factor A3-domain. Journal of Biological Chemistry, 276, (pp. 9985-9991) (7 p.).
Huizinga, E.G., Schouten, A., Connolly, T.M., Kroon, J., Sixma, J.J. & Gros, P. (2001). The structure of leech anti-plated protein, an inhibitor of haemostasis. Acta Crystallographica Section D: Biological Crystallography, D 57, (pp. 1071-1078) (8 p.).
  2000 - Wetenschappelijke publicaties
Van Der Plas, R.M., Gomes, L., Marquart, J.A., Vink, T., Meijers, J.C.M., De, GrootP.G., Sixma, J.J. & Huizinga, E.G. (22-12-2000). Binding of von Willebrand factor to collagen type III: Role of specific amino acids in the collagen binding domain of vWF and effects of neighboring domains. Thrombosis and Haemostasis, 84 (6), (pp. 1005-1011) (7 p.).
Vanhoorelbeke, K., van der Plas, R.M., Vandecasteele, G., Vauterin, S., Huizinga, E.G., Sixma, J.J. & Deckmijn, H. (2000). Sequence alignment between vWF and peptides inhibiting the vWF-collagen interaction does not result in the identification of a collagen-binding site in vWF. Thrombosis and Haemostasis, 84, (pp. 621-625) (5 p.).
  1999 - Wetenschappelijke publicaties
Verkley, M.W., IJsseldijk, M.J.W., Heijnen-Snyder, G.J., Huizinga, E.G., Morton, L.F., Knight, C.G., Sixma, J.J., de Groot, P.G. & Barnes, M.J. (1999). Adhesive domains in the collagen III fragment a1 (III)CB4 that support a2b1- and von Willebrand factor-mediated platelet adhesion under flow conditions. Thrombosis and Haemostasis, 82, (pp. 1137-1144) (8 p.).
Van Der Plas, R. Martijn, Schiphorst, Marion E., Huizinga, Eric G., Hené, Ronald J., Verdonck, Leo F., Sixma, Jan J. & Fijnheer, Rob (01-06-1999). von Willebrand factor proteolysis is deficient in classic, but not in bone marrow transplantation-associated, thrombotic thrombocytopenic purpura. Blood, 93 (11), (pp. 3798-3802) (5 p.).
  1997 - Wetenschappelijke publicaties
Huizinga, E.G., van der Plas, R.M., Kroon, J., Sixma, J.J. & Gros, P. (1997). Crystal structure of the A3 domain of human von Willebrand factor: implications for collagen binding. Structure with Folding & design, 5, (pp. 1147-1156) (10 p.).
Sixma, J.J., van Zanten, G.H., Huizinga, E.G., van der Plas, R.M., Verkleij, M., Wu, Y.P., Gros, P. & de Groot, P.G. (1997). Platelet adhesion to collagen: an update. Thrombosis and Haemostasis, 78, (pp. 434-438) (5 p.).
  1992 - Wetenschappelijke publicaties
Huizinga, E.G., Van Zanten, B.A.M., Duine, J.A., Jongejan, J.A., Huitema, F., Wilson, K.S. & Hol, W.G.J. (22-12-1992). Active site structure of methylamine dehydrogenase: Hydrazines identify C6 as the reactive site of the tryptophan-derived quinone cofactor. Biochemistry, 31 (40), (pp. 9789-9795) (7 p.).
Chen, L., Mathews, F.S., Davidson, V.L., Huizinga, E.G., Vellieux, F.M.D. & Hol, W.G.J. (22-12-1992). Three-dimensional structure of the quinoprotein methylamine dehydrogenase from Paracoccus denitrificans determined by molecular replacement at 2.8 Å resolution. Proteins: Structure, Function and Genetics, 14 (2), (pp. 288-299) (12 p.).
  1991 - Wetenschappelijke publicaties
Chen, L., Mathews, F.S., Davidson, V.L., Huizinga, E.G., Vellieux, F.M.D., Duine, J.A. & Hol, W.G.J. (22-12-1991). Crystallographic investigations of the tryptophan-derived cofactor in the quinoprotein methylamine dehydrogenase. FEBS Letters, 287 (1-2), (pp. 163-166) (4 p.).
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Gegenereerd op 2018-09-22 13:51:23
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dr. E.G. Huizinga Contactgegevens
Hugo R. Kruytgebouw

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Telefoonnummer direct 030 253 2866
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Gegenereerd op 2018-09-22 13:51:23
Laatst bijgewerkt op 09-03-2018