prof. dr. A.S. (Anna) Akhmanova
a.akhmanova@uu.nl
Gegenereerd op 2017-11-18 18:41:20


Leeropdracht
Celbiologie
Benoemingsdatum 01-01-2011
Oratiedatum 01-02-2012
Profiel

My group studies cytoskeletal organisation and trafficking processes, which 
contribute to cell polarisation, differentiation, vertebrate development and 
human disease. We are interested in understanding, at a systems level, in 
how different aspects of cell architecture are coordinated. The main focus of 
our studies is the microtubule cytoskeleton. Our research relies on combining 
high-resolution live cell imaging and quantitative analysis of cytoskeletal 
dynamics, measurement of protein dynamics using advanced microscopic 
assays, in vitro reconstitution of dynamic cytoskeleton-based processes and 
different methods of identification of protein-protein interactions (in vitro 
binding studies, pull-down assays, yeast two-hybrid screens and mass 
spectrometry-based protein identification). In addition to cultured cells, we 
employ mouse knockout technologies and couple mouse genetic modification 
(such as GFP knock-in technology) to live tissue imaging. In collaboration 
with mathematicians we are working on development of automated analysis 
and modelling of cytoskeletal dynamics and vesicle transport.

Microtubule-based processes are essential for cell division, normal 
functioning of large cells such as neurons and for intracellular transport of 
pathogens; therefore, our studies are relevant for combating abnormal cell 
proliferation, neurodegeneration and infectious diseases.

  • Member of the European Molecular Biology Organization (EMBO)
  • Member the Royal Netherlands Academy of Arts and Sciences (KNAW)
  • ERC Synergy grant 2013 (together with Dr. Marileen Dogterom, TU Delft)
  • ALW Vernieuwingsimpuls VICI 2007 
  • NWO Vernieuwingsimpuls VIDI 2001

Betrokken bij de opleiding(en)
Gegenereerd op 2017-11-18 18:41:20
Curriculum vitae

Anna Akhmanova studied biochemistry and molecular biology at the Moscow State University. She received her PhD in 1997 at the University of Nijmegen. She worked as a post-doc at the Department of Microbiology and Evolutionary Biology at the University of Nijmegen and at the Department of Cell Biology at the Erasmus Medical Center in Rotterdam. In 2001, she started her own research group at the Department of Cell Biology at the Erasmus Medical Center, Rotterdam. Since 2011, Anna Akhmanova is professor of Cell Biology at Utrecht University.

Gegenereerd op 2017-11-18 18:41:20

Selected Publications

2015

Akhmanova A, Hoogenraad CC (2015). Microtubule minus-end-targeting proteins. Curr Biol, 25: R162-71.


2014

Yau KW, van Beuningen SF, Cunha-Ferreira I, Cloin BM, van Battum EY, Will L, Schatzle P, Tas RP, van Krugten J, Katrukha EA, Jiang K, Wulf PS, Mikhaylova M, Harterink M, Pasterkamp RJ, Akhmanova A, Kapitein LC, Hoogenraad CC (2014). Microtubule minus-end binding protein CAMSAP2 controls axon specification and dendrite development. Neuron, 82: 1058-73.

Schlager MA, Serra-Marques A, Grigoriev I, Gumy LF, Esteves da Silva M, Wulf PS, Akhmanova A, Hoogenraad CC (2014). Bicaudal d family adaptor proteins control the velocity of Dynein-based movements. Cell Rep, 8:1248-56.

Preciado Lopez M, Huber F, Grigoriev I, Steinmetz MO, Akhmanova A, Koenderink GH, Dogterom M. (2014). Actin-microtubule coordination at growing microtubule ends. Nat Commun, 5:4778.

Jiang K, Hua S, Mohan R, Grigoriev I, Yau KW, Liu Q, Katrukha EA, Altelaar AF, Heck AJ, Hoogenraad CC, Akhmanova A. 2014. Microtubule minus-end stabilization by polymerization-driven CAMSAP deposition. Dev Cell, 28:295-309.

Doodhi H, Katrukha EA, Kapitein LC, Akhmanova A (2014). Mechanical and geometrical constraints control Kinesin-based microtubule guidance. Curr Biol 24:322-8.

2013

van der Vaart B, van Riel WE, Doodhi H, Kevenaar JT, Katrukha EA, Gumy L, Bouchet BP, Grigoriev I, Spangler SA, Yu KL, Wulf PS, Wu J, Lansbergen G, van Battum EY, Pasterkamp RJ, Mimori-Kiyosue Y, Demmers J, Olieric N, Maly IV, Hoogenraad CC, and Akhmanova A (2013). CFEOM1-associated kinesin KIF21A is a cortical microtubule growth inhibitor. Dev Cell. 27: 145-60.

Mohan R, Katrukha EA, Doodhi H, Smal I, Meijering E, Kapitein LC, Steinmetz MO, and Akhmanova A (2013). End-binding proteins sensitize microtubules to the action of microtubule-targeting agents. Proc Natl Acad Sci U S A. 110: 8900-5.

Hu DJ, Baffet AD, Nayak T, Akhmanova A, Doye V, and Vallee RB (2013). Dynein recruitment to nuclear pores activates apical nuclear migration and mitotic entry in brain progenitor cells. Cell 154: 1300-13.

van Spronsen M, Mikhaylova M, Lipka J, Schlager MA, van den Heuvel DJ, Kuijpers M, Wulf PS, Keijzer N, Demmers J, Kapitein LC, Jaarsma D, Gerritsen HC, Akhmanova A, Hoogenraad CC (2013) TRAK/Milton Motor-Adaptor Proteins Steer Mitochondrial Trafficking to Axons and Dendrites. Neuron 77: 485-502.


2012

van der Vaart B, Franker MA, Kuijpers M, Hua S, Bouchet BP, Jiang K, Grigoriev I, Hoogenraad CC, Akhmanova A (2012) Microtubule plus-end tracking proteins SLAIN1/2 and ch-TOG promote axonal development. J Neurosci 32: 14722-14728.

Splinter D, Razafsky DS, Schlager MA, Serra-Marques A, Grigoriev I, Demmers J, Keijzer N, Jiang K, Poser I, Hyman AA, Hoogenraad CC, King SJ, Akhmanova A (2012) BICD2, dynactin, and LIS1 cooperate in regulating dynein recruitment to cellular structures. Mol Biol Cell 23: 4226-4241.

Ratheesh A, Gomez GA, Priya R, Verma S, Kovacs EM, Jiang K, Brown NH, Akhmanova A, Stehbens SJ, Yap AS (2012) Centralspindlin and alpha-catenin regulate Rho signalling at the epithelial zonula adherens. Nat Cell Biol 14: 818-828.

Jiang K, Toedt G, Montenegro Gouveia S, Davey NE, Hua S, van der Vaart B, Grigoriev I, Larsen J, Pedersen LB, Bezstarosti K, Lince-Faria M, Demmers J, Steinmetz MO, Gibson TJ, Akhmanova A (2012) A Proteome-wide screen for mammalian SxIP motif-containing microtubule plus-end tracking proteins. Curr Biol 22: 1800-1807.

2011

van der Vaart B, Manatschal C, Grigoriev I, Olieric V, Gouveia SM, Bjelic S, Demmers J, Vorobjev I, Hoogenraad CC, Steinmetz MO, Akhmanova A (2011) SLAIN2 links microtubule plus end-tracking proteins and controls microtubule growth in interphase. J Cell Biol 193: 1083-1099.

Kovacs EM, Verma S, Ali RG, Ratheesh A, Hamilton NA, Akhmanova A, Yap AS (2011) N-WASP regulates the epithelial junctional actin cytoskeleton through a non-canonical post-nucleation pathway. Nat Cell Biol 13: 934-943.

Jiang K, Akhmanova A (2011) Microtubule tip-interacting proteins: a view from both ends. Curr Opin Cell Biol 23: 94-101.

Grigoriev I, Yu KL, Martinez-Sanchez E, Serra-Marques A, Smal I, Meijering E, Demmers J, Peranen J, Pasterkamp RJ, van der Sluijs P, Hoogenraad CC, Akhmanova A (2011) Rab6, Rab8, and MICAL3 cooperate in controlling docking and fusion of exocytotic carriers. Curr Biol 21: 967-974.

Akhmanova A, Dogterom M (2011) Kinesins lead aging microtubules to catastrophe. Cell 147: 966-968.

2010

Splinter D, Tanenbaum ME, Lindqvist A, Jaarsma D, Flotho A, Yu KL, Grigoriev I, Engelsma D, Haasdijk ED, Keijzer N, Demmers J, Fornerod M, Melchior F, Hoogenraad CC, Medema RH, Akhmanova A (2010) Bicaudal D2, dynein, and kinesin-1 associate with nuclear pore complexes and regulate centrosome and nuclear positioning during mitotic entry. PLoS Biol 8: e1000350.

Montenegro Gouveia S, Leslie K, Kapitein LC, Buey RM, Grigoriev I, Wagenbach M, Smal I, Meijering E, Hoogenraad CC, Wordeman L, Steinmetz MO, Akhmanova A (2010) In vitro reconstitution of the functional interplay between MCAK and EB3 at microtubule plus ends. Curr Biol 20: 1717-1722.

Gouveia SM, Akhmanova A (2010) Cell and molecular biology of microtubule plus end tracking proteins: end binding proteins and their partners. Int Rev Cell Mol Biol 285: 1-74.

Akhmanova A, Steinmetz MO (2010) Microtubule +TIPs at a glance. J Cell Sci 123: 3415-3419.

Akhmanova A, Hammer JA, 3rd (2010) Linking molecular motors to membrane cargo. Curr Opin Cell Biol 22: 479-487.

2009

Lomakin AJ, Semenova I, Zaliapin I, Kraikivski P, Nadezhdina E, Slepchenko BM, Akhmanova A, Rodionov V (2009) CLIP-170-dependent capture of membrane organelles by microtubules initiates minus-end directed transport. Dev Cell 17: 323-333.

Komarova Y, De Groot CO, Grigoriev I, Gouveia SM, Munteanu EL, Schober JM, Honnappa S, Buey RM, Hoogenraad CC, Dogterom M, Borisy GG, Steinmetz MO, Akhmanova A (2009) Mammalian end binding proteins control persistent microtubule growth. J Cell Biol 184: 691-706.

Honnappa S, Gouveia SM, Weisbrich A, Damberger FF, Bhavesh NS, Jawhari H, Grigoriev I, van Rijssel FJ, Buey RM, Lawera A, Jelesarov I, Winkler FK, Wuthrich K, Akhmanova A, Steinmetz MO (2009) An EB1-binding motif acts as a microtubule tip localization signal. Cell 138: 366-376.

2008

Grigoriev I, Gouveia SM, van der Vaart B, Demmers J, Smyth JT, Honnappa S, Splinter D, Steinmetz MO, Putney JW, Jr., Hoogenraad CC, Akhmanova A (2008) STIM1 is a MT-plus-end-tracking protein involved in remodeling of the ER. Curr Biol 18: 177-182.

Akhmanova A, Yap AS (2008) Organizing junctions at the cell-cell interface. Cell 135: 791-793.

Akhmanova A, Steinmetz MO (2008) Tracking the ends: a dynamic protein network controls the fate of microtubule tips. Nat Rev Mol Cell Biol 9: 309-322.

2007

Grigoriev I, Splinter D, Keijzer N, Wulf PS, Demmers J, Ohtsuka T, Modesti M, Maly IV, Grosveld F, Hoogenraad CC, Akhmanova A (2007) Rab6 regulates transport and targeting of exocytotic carriers. Dev Cell 13: 305-314.

2006

Lansbergen G, Grigoriev I, Mimori-Kiyosue Y, Ohtsuka T, Higa S, Kitajima I, Demmers J, Galjart N, Houtsmuller AB, Grosveld F, Akhmanova A (2006) CLASPs attach microtubule plus ends to the cell cortex through a complex with LL5beta. Dev Cell 11: 21-32.

2005

Mimori-Kiyosue Y, Grigoriev I, Lansbergen G, Sasaki H, Matsui C, Severin F, Galjart N, Grosveld F, Vorobjev I, Tsukita S, Akhmanova A (2005) CLASP1 and CLASP2 bind to EB1 and regulate microtubule plus-end dynamics at the cell cortex. J Cell Biol 168: 141-153.

Akhmanova A, Mausset-Bonnefont AL, van Cappellen W, Keijzer N, Hoogenraad CC, Stepanova T, Drabek K, van der Wees J, Mommaas M, Onderwater J, van der Meulen H, Tanenbaum ME, Medema RH, Hoogerbrugge J, Vreeburg J, Uringa EJ, Grootegoed JA, Grosveld F, Galjart N (2005) The microtubule plus-end-tracking protein CLIP-170 associates with the spermatid manchette and is essential for spermatogenesis. Genes Dev 19: 2501-2515.

Akhmanova A, Hoogenraad CC (2005) Microtubule plus-end-tracking proteins: mechanisms and functions. Curr Opin Cell Biol 17: 47-54.

2004

Lansbergen G, Komarova Y, Modesti M, Wyman C, Hoogenraad CC, Goodson HV, Lemaitre RP, Drechsel DN, van Munster E, Gadella TW, Jr., Grosveld F, Galjart N, Borisy GG, Akhmanova A (2004) Conformational changes in CLIP-170 regulate its binding to microtubules and dynactin localization. J Cell Biol 166: 1003-1014.

 

 

Alle publicaties
  2017 - Wetenschappelijke publicaties
Atherton, Joseph, Jiang, Kai, Stangier, Marcel M, Luo, Yanzhang, Hua, Shasha, Houben, Klaartje, van Hooff, Jolien J E, Joseph, Agnel-Praveen, Scarabelli, Guido, Grant, Barry J, Roberts, Anthony J, Topf, Maya, Steinmetz, Michel O., Baldus, Marc, Moores, Carolyn A & Akhmanova, Anna (2017). A structural model for microtubule minus-end recognition and protection by CAMSAP proteins. Nature Structural and Molecular Biology, 24 (11), (pp. 931-943).
Au, F.K., Jia, Y., Jiang, K., Grigoriev, I.S., Hau, B.K., Shen, Y., Du, S., Akhmanova, A.S. & Qi, R.Z. (09-01-2017). GAS2L1 Is a Centriole-Associated Protein Required for Centrosome Dynamics and Disjunction. Developmental Cell, 40 (1), (pp. 81-94) (14 p.).
van Riel, Wilhelmina E, Rai, Ankit, Bianchi, Sarah, Katrukha, Eugene A, Liu, Qingyang, Heck, Albert Jr, Hoogenraad, Casper C, Steinmetz, Michel O, Kapitein, Lukas C & Akhmanova, Anna (2017). Kinesin-4 KIF21B is a potent microtubule pausing factor. eLife, 6 (30 p.).
Jiang, Kai, Rezabkova, Lenka, Hua, Shasha, Liu, Qingyang, Capitani, Guido, Altelaar, Maarten, Heck, Albert J R, Kammerer, Richard A, Steinmetz, Michel O & Akhmanova, Anna (2017). Microtubule minus-end regulation at spindle poles by an ASPM-katanin complex. Nature Cell Biology, 19 (5), (pp. 480-492) (13 p.).
  2016 - Wetenschappelijke publicaties
Hoogenraad, Casper C & Akhmanova, Anna (2016). Bicaudal D Family of Motor Adaptors - Linking Dynein Motility to Cargo Binding. Trends in Cell Biology, 26 (5), (pp. 327-40) (14 p.). Copyright © 2016 Elsevier Ltd. All rights reserved..
Rezabkova, Lenka, Kraatz, Sebastian H W, Akhmanova, Anna, Steinmetz, Michel O & Kammerer, Richard A (26-08-2016). Biophysical and Structural Characterization of the Centriolar Protein Cep104 Interaction Network. Journal of Biological Chemistry, 291 (35), (pp. 18496-504) (9 p.). © 2016 by The American Society for Biochemistry and Molecular Biology, Inc..
Sharma, Ashwani, Aher, Amol, Dynes, Nicola J, Frey, Daniel, Katrukha, Eugene A, Jaussi, Rolf, Grigoriev, Ilya, Croisier, Marie, Kammerer, Richard A, Akhmanova, Anna, Gönczy, Pierre & Steinmetz, Michel O (2016). Centriolar CPAP/SAS-4 Imparts Slow Processive Microtubule Growth. Developmental Cell, 37 (4), (pp. 362-76) (15 p.). Copyright © 2016 The Authors. Published by Elsevier Inc. All rights reserved..
Noordstra, Ivar, Liu, Qingyang, Nijenhuis, Wilco, Hua, Shasha, Jiang, Kai, Baars, Matthijs, Remmelzwaal, Sanne, Martin, Maud, Kapitein, Lukas & Akhmanova, Anna (15-11-2016). Control of apico-basal epithelial polarity by the microtubule minus-end-binding protein CAMSAP3 and spectraplakin ACF7. Journal of Cell Science, 129 (22), (pp. 4278-4288) (11 p.). © 2016. Published by The Company of Biologists Ltd..
Kuijpers, Marijn, van de Willige, Dieudonnée, Freal, Amélie, Chazeau, Anaël, Franker, Mariella A, Hofenk, Jasper, Rodrigues, Ricardo J Cordeiro, Kapitein, Lukas C, Akhmanova, Anna, Jaarsma, Dick & Hoogenraad, Casper C (03-02-2016). Dynein Regulator NDEL1 Controls Polarized Cargo Transport at the Axon Initial Segment. Neuron, 89 (3), (pp. 461-71) (11 p.). Copyright © 2016 Elsevier Inc. All rights reserved..
Guesdon, Audrey, Bazile, Franck, Buey, Rubén M, Mohan, Renu, Monier, Solange, García, Ruddi Rodríguez, Angevin, Morgane, Heichette, Claire, Wieneke, Ralph, Tampé, Robert, Duchesne, Laurence, Akhmanova, Anna, Steinmetz, Michel O & Chrétien, Denis (2016). EB1 interacts with outwardly curved and straight regions of the microtubule lattice. Nature Cell Biology, 18 (10), (pp. 1102-8) (7 p.).
Kevenaar, Josta T, Bianchi, Sarah, van Spronsen, Myrrhe, Olieric, Natacha, Lipka, Joanna, Frias, Cátia P, Mikhaylova, Marina, Harterink, Martin, Keijzer, Nanda, Wulf, Phebe S, Hilbert, Manuel, Kapitein, Lukas C, de Graaff, Esther, Akhmanova, Anna, Steinmetz, Michel O & Hoogenraad, Casper C (04-04-2016). Kinesin-Binding Protein Controls Microtubule Dynamics and Cargo Trafficking by Regulating Kinesin Motor Activity. Current Biology, 26 (7), (pp. 849-861) (13 p.). Copyright © 2016 Elsevier Ltd. All rights reserved..
Bouchet, Benjamin P, Noordstra, Ivar, van Amersfoort, Miranda, Katrukha, Eugene A, Ammon, York-Christoph, Ter Hoeve, Natalie D, Hodgson, Louis, Dogterom, Marileen, Derksen, Patrick W B & Akhmanova, Anna (19-12-2016). Mesenchymal Cell Invasion Requires Cooperative Regulation of Persistent Microtubule Growth by SLAIN2 and CLASP1. Developmental Cell, 39 (6), (pp. 708-723) (16 p.). Copyright © 2016 Elsevier Inc. All rights reserved..
Liu, Qingyang, Liu, Fan, Yu, Ka Lou, Tas, Roderick, Grigoriev, Ilya, Remmelzwaal, Sanne, Marques, Andrea, Kapitein, Lukas C, Heck, Albert J R & Akhmanova, Anna (15-08-2016). MICAL3 flavoprotein monooxygenase forms a complex with centralspindlin and regulates cytokinesis. Journal of Biological Chemistry (23 p.). Copyright © 2016, The American Society for Biochemistry and Molecular Biology..
van de Willige, Dieudonnée, Hoogenraad, Casper C & Akhmanova, Anna (2016). Microtubule plus-end tracking proteins in neuronal development. Cellular and Molecular Life Sciences, 73 (10), (pp. 2053-77) (25 p.).
Wu, Jingchao, de Heus, Cecilia, Liu, Qingyang, Bouchet, Benjamin P, Noordstra, Ivar, Jiang, Kai, Hua, Shasha, Martin, Maud, Yang, Chao, Grigoriev, Ilya, Katrukha, Eugene A, Altelaar, A F Maarten, Hoogenraad, Casper C, Qi, Robert Z, Klumperman, Judith & Akhmanova, Anna (17-09-2016). Molecular Pathway of Microtubule Organization at the Golgi Apparatus. Developmental Cell, 39 (1), (pp. 44–60). Copyright © 2016 Elsevier Inc. All rights reserved..
Portegijs, Vincent, Fielmich, Lars-Eric, Galli, Matilde, Schmidt, Ruben, Munoz Peralta, Javier, van Mourik, Tim, Akhmanova, Anna, Heck, Albert J R, Boxem, Mike & van den Heuvel, Sander (2016). Multisite Phosphorylation of NuMA-Related LIN-5 Controls Mitotic Spindle Positioning in C. elegans. PLoS Genetics, 12 (10), (pp. 1-32) (32 p.).
Bianchi, Sarah, van Riel, Wilhelmina E, Kraatz, Sebastian H W, Olieric, Natacha, Frey, Daniel, Katrukha, Eugene A, Jaussi, Rolf, Missimer, John, Grigoriev, Ilya, Olieric, Vincent, Benoit, Roger M, Steinmetz, Michel O, Akhmanova, Anna & Kammerer, Richard A (03-08-2016). Structural basis for misregulation of kinesin KIF21A autoinhibition by CFEOM1 disease mutations. Scientific Reports, 6.
Bouchet, Benjamin P, Gough, Rosemarie E, Ammon, York-Christoph, van de Willige, Dieudonnée, Post, Harm, Jacquemet, Guillaume, Altelaar, Maarten, Heck, Albert Jr, Goult, Ben T & Akhmanova, Anna (13-07-2016). Talin-KANK1 interaction controls the recruitment of cortical microtubule stabilizing complexes to focal adhesions. eLife, 5.
Doodhi, Harinath, Prota, Andrea E, Rodríguez-García, Ruddi, Xiao, Hui, Custar, Daniel W, Bargsten, Katja, Katrukha, Eugene A, Hilbert, Manuel, Hua, Shasha, Jiang, Kai, Grigoriev, Ilya, Yang, Chia-Ping H, Cox, David, Horwitz, Susan Band, Kapitein, Lukas C, Akhmanova, Anna & Steinmetz, Michel O (11-07-2016). Termination of Protofilament Elongation by Eribulin Induces Lattice Defects that Promote Microtubule Catastrophes. Current Biology, 26 (13), (pp. 1713-21) (9 p.). Copyright © 2016 Elsevier Ltd. All rights reserved..
Akhmanova, Anna & van den Heuvel, Sander (2016). Tipping the spindle into the right position. Journal of Cell Biology, 213 (3), (pp. 293-5) (3 p.). © 2016 Akhmanova and van den Heuvel..
  2015 - Wetenschappelijke publicaties
Long, Yuchen, Smet, Wouter, Cruz-Ramírez, Alfredo, Castelijns, Bas, de Jonge, Wim, Mähönen, Ari Pekka, Bouchet, Benjamin P, Perez, Gabino Sanchez, Akhmanova, Anna, Scheres, Ben & Blilou, Ikram (2015). Arabidopsis BIRD Zinc Finger Proteins Jointly Stabilize Tissue Boundaries by Confining the Cell Fate Regulator SHORT-ROOT and Contributing to Fate Specification. Plant Cell, 27 (4), (pp. 1185-1199) (15 p.). © 2015 American Society of Plant Biologists. All rights reserved..
Akhmanova, Anna & Steinmetz, Michel O (2015). Control of microtubule organization and dynamics - two ends in the limelight. Nature Reviews Molecular Cell Biology, 16 (12), (pp. 711-26) (16 p.).
Akhmanova, Anna & Hoogenraad, Casper C (16-02-2015). Microtubule minus-end-targeting proteins. Current Biology, 25 (4), (pp. R162-71).
The, Inge, Ruijtenberg, Suzan, Bouchet, Benjamin P, Cristobal Gonzalez de Durana, Alba, Prinsen, Martine B W, van Mourik, Tim, Koreth, John, Xu, Huihong, Heck, Albert J R, Akhmanova, Anna, Cuppen, Edwin, Boxem, Mike, Munoz Murillo, Ara & van den Heuvel, Sander (2015). Rb and FZR1/Cdh1 determine CDK4/6-cyclin D requirement in C. elegans and human cancer cells. Nature Communications, 6, (pp. 5906).
Long, Yuchen, Goedhart, Joachim, Schneijderberg, Martinus, Terpestra, Inez, Shimotohno, Akie, Bouchet, Benjamin P, Akhmanova, Anna, Gadella, Theodorus W J, Heidstra, Renze, Scheres, Ben & Blilou, Ikram (2015). SCARECROW-LIKE23 and SCARECROW jointly specify endodermal cell fate but distinctly control SHORT-ROOT movement. Plant Journal, 84 (4), (pp. 773–784). This article is protected by copyright. All rights reserved..
van Beuningen, Sam F B, Will, Lena, Harterink, Martin, Chazeau, Anaël, van Battum, Eljo Y, Frias, Cátia P, Franker, Mariella A M, Katrukha, Eugene A, Stucchi, Riccardo, Vocking, Karin, Antunes, Ana T, Slenders, Lotte, Doulkeridou, Sofia, Sillevis Smitt, Peter, Altelaar, A F Maarten, Post, Jan A, Akhmanova, Anna, Pasterkamp, R Jeroen, Kapitein, Lukas C, de Graaff, Esther & Hoogenraad, Casper C (06-12-2015). TRIM46 Controls Neuronal Polarity and Axon Specification by Driving the Formation of Parallel Microtubule Arrays. Neuron, (pp. 1208-1226). Copyright © 2015 Elsevier Inc. All rights reserved..
  2014 - Wetenschappelijke publicaties
Akhmanova, A.S. (27-01-2014) Invited speaker Seminar at Instituto Gulbenkian de Ciencia Lisbon (27-01-2014)
Akhmanova, A.S. (25-09-2014) Participant 1st International SBCF Meeting "Building the Cell" Paris (25-09-2014)
Jaarsma, Dick, van den Berg, Robert, Wulf, Phebe S, van Erp, Susan, Keijzer, Nanda, Schlager, Max A, de Graaff, Esther, De Zeeuw, Chris I, Pasterkamp, R Jeroen, Akhmanova, Anna & Hoogenraad, Casper C (2014). A role for Bicaudal-D2 in radial cerebellar granule cell migration. Nature Communications, 5, (pp. 3411).
Preciado Lopez, M., Huber, F. Huber, Grigoriev, Ilya, Steinmetz, M.O., Akhmanova, Anna, Koenderink, G.H. & Dogterom, M. (27-08-2014). Actin-microtubule coordination at growing microtubule ends. Nature Communications, 5 (4778) (9 p.).
Akhmanova, A.S. (2014) Member Agence Nationale de la Recherche (External organisation) Grant Panel Member Agence Nationale de la Recherche
Akhmanova, A.S. (2014) Referee Agence Nationale de la Recherche France (Publisher)
Akhmanova, A.S. (2014) Referee BBSRC UK (Publisher)
Schlager, M.A., Serra-Marquez, A., Grigoriev, Ilya, Gumy, Laura, Estevez da Silva, M., Wulf, Phebe, Akhmanova, Anna & Hoogenraad, Casper (11-09-2014). Bicaudal d family adaptor proteins control the velocity of Dynein-based movements. Cell Reports, 8 (5), (pp. 1248-1256).
Akhmanova, A.S. (2014) Editorial board member Bioarchitecture (Journal)
Akhmanova, A.S. (2014) Editorial board member Bioarchitecture (Journal)
Akhmanova, A.S. (11-10-2014) Organiser Biophysical Society Thematic Meeting "Disordered Motifs and Domains in Cell Control" Dublin (11-10-2014 - 15-10-2014)
Akhmanova, A.S. (2014) Guest editor BMC Cell Biology (Journal) Section editor
Akhmanova, A.S. (2014) Peer reviewer Cell Reports [E] (Journal)
Akhmanova, A.S. (13-10-2014) Invited speaker Biophysical Society Thematic Meeting "Disordered Motifs and Domains in Cell Control" Dublin (11-10-2014 - 15-10-2014) Control of protein localization to microtubule tips by disordered motifs
Akhmanova, A.S. (2014) Peer reviewer Current Biology (Journal)
Akhmanova, A.S. (2014) Peer reviewer Current Biology (Journal)
Akhmanova, A.S. (16-07-2014) Invited speaker QBio Summer School Utrecht (14-07-2014 - 18-07-2014) Cytoskeletal dynamics in cells
Akhmanova, A.S. (2014) Peer reviewer Developmental Cell (Journal)
Akhmanova, A.S. (2014) Peer reviewer Developmental Cell (Journal)
Akhmanova, A.S. (2014) Chair Dutch Microscopical Society (External organisation) Chair of the Board of the Dutch Microscopical Society<br/><br/>Chair of the board
Akhmanova, A.S. (2014) Referee Dynasty Foundation Russia (Publisher)
Akhmanova, A.S. (2014) Peer reviewer eLife (Journal)
Akhmanova, A.S. (2014) Editorial board member eLife (Journal)
Akhmanova, A.S. (2014) Member EMBO Long Term Fellowship (External organisation) Grant Panel member EMBO Long Term Fellowship
Akhmanova, A.S. (2014) Editorial board member Encyclopedia of Cell Biology (Journal) Section editor
Akhmanova, A.S. (2014) Referee ERC Consolidator grant (Publisher)
Akhmanova, A.S. (2014) Member ERC starting grant (External organisation) Grant Panel member ERC starting grant
Akhmanova, A.S. (2014) Editorial board member Frontiers in Cell and Developmental Biology (Journal)
Preciado Lopez, M., Huber, F., Grigoriev, Ilya, Steinmetz, M.O., Akhmanova, Anna, Dogterom, M. & Koenderink, G.H. (2014). In vitro reconstitution of dynamic microtubules interacting with actin filament networks. Methods in Enzymology, 540, (pp. 301-320) (20 p.).
Akhmanova, A.S. (2014) Member Institute Curie Orsay (External organisation) Faculty search committee
Akhmanova, A.S. (2014) Member Institute Curie Orsay (External organisation) AERES evoluation committee
Akhmanova, A.S. (01-07-2014) Invited speaker Invited seminar at University of Illinois at Chicago Chicago (01-07-2014)
Akhmanova, A.S. (2014) Referee Israel Science Foundation (Publisher)
Akhmanova, A.S. (2014) Peer reviewer Journal of Biological Chemistry (Journal)
Akhmanova, A.S. (2014) Editorial board member Journal of Biological Chemistry (Journal)
Akhmanova, A.S. (2014) Peer reviewer Journal of Cell Biology (Journal)
Akhmanova, A.S. (2014) Peer reviewer Journal of Cell Science (Journal)
Pedersen, L.B. & Akhmanova, Anna (2014). Kif7 keeps cilia tips in shape. Nature Cell Biology, 16, (pp. 623-625) (3 p.).
Doodhi, Harinath, Katrukha, Eugene, Kapitein, Lukas & Akhmanova, Anna (2014). Mechanical and geometrical constraints control kinesin-based microtubule guidance. Current Biology, 24, (pp. 322) (328 p.).
Akhmanova, A.S. (18-02-2014) Invited speaker Invited seminar at University of Dundee Dundee (18-02-2014) Microtubule dynamics: a tale of two ends
Akhmanova, A.S. (06-11-2014) Invited speaker Invited seminar at Radboud University Medical Center Nijmegen (06-11-2014) Microtubule dynamics: a tale of two ends
Akhmanova, A.S. (06-02-2014) Invited speaker Seminar at Institute Curie Orsay Paris (06-02-2014) Microtubule dynamics: a tale of two ends
Yau, Kah Wai, van Beuningen, Sam F B, Cunha-Ferreira, Inês, Cloin, Bas M C, van Battum, Eljo Y, Will, Lena, Schätzle, Philipp, Tas, Roderick P, van Krugten, Jaap, Katrukha, Eugene A, Jiang, Kai, Wulf, Phebe S, Mikhaylova, Marina, Harterink, Martin, Pasterkamp, R Jeroen, Akhmanova, Anna, Kapitein, Lukas C & Hoogenraad, Casper C (04-06-2014). Microtubule minus-end binding protein CAMSAP2 controls axon specification and dendrite development. Neuron, 82 (5), (pp. 1058-73) (16 p.). Copyright © 2014 Elsevier Inc. All rights reserved..
Jiang, Kai, Hua, Shasha, Mohan, Renu, Grigoriev, Ilya, Yau, Kah Wai, Liu, Qingyang, Katrukha, Eugene A, Altelaar, A F Maarten, Heck, Albert J R, Hoogenraad, Casper C & Akhmanova, Anna (10-02-2014). Microtubule minus-end stabilization by polymerization-driven CAMSAP deposition. Developmental Cell, 28 (3), (pp. 295-309) (15 p.). Copyright © 2014 Elsevier Inc. All rights reserved..
Akhmanova, A.S. (2014) Peer reviewer Molecular Biology of the Cell (Journal)
Akhmanova, A.S. (2014) Referee National Science Center Poland (Publisher)
Akhmanova, A.S. (2014) Peer reviewer PloS Biology [E] (Journal)
Akhmanova, A.S. (2014) Peer reviewer PLoS One (Journal)
Akhmanova, A.S. (2014) Peer reviewer Proceedings of the National Academy of Sciences of the United States of America (Journal)
Akhmanova, A.S. (14-07-2014 14-07-2018) Organiser QBio Summer School Utrecht (14-07-2014 - 18-07-2014)
Akhmanova, A.S. (09-12-2014) Invited speaker Invited seminar at Institut Albert Bonniot, Grenoble Grenoble (09-12-2014) Regulation of cell architecture by microtubule end-binding proteins
Akhmanova, A.S. (11-11-2014) Invited speaker Invited seminar at ETH, Zurich Zurich (11-11-2014) Regulation of cell architecture by microtubule end-binding proteins
Akhmanova, A.S. (24-04-2014) Invited speaker Invited seminar at Scripps Institute, San Diego San Diego (24-04-2014) Regulation of cell architecture by microtubule end-binding proteins
Akhmanova, A.S. (30-12-2014) Invited speaker Invited seminar at Northwestern University, Chicago (30-06-2014) Regulation of cell architecture by microtubule end-binding proteins
Akhmanova, A.S. (28-04-2014) Invited speaker Invited seminar at University of Pennsylvania, Philadelphia Philadelphia (28-04-2014) Regulation of cell architecture by microtubule end-binding proteins
Akhmanova, A.S. (15-04-2014) Invited speaker 20th Bijvoet Tutorial Symposium Soesterberg (15-04-2014) Regulation of cell architecture by microtubule end-binding proteins
Akhmanova, A.S. (28-04-2014) Invited speaker Invited seminar at University of Pennsylvania (28-04-2014) Regulation of cell architecture by microtubule end-binding proteisn
Akhmanova, A.S. (10-07-2014) Invited speaker Gordon Conference "Muscles and Molecular Motors" West Dover (10-07-2014) Regulation of microtubule dynamics by kinesin-4 family members
Akhmanova, A.S. (28-01-2014) Invited speaker IGC PhD Course on Structural and Molecular Biology (28-01-2014) Regulation of microtubule skeleton
Akhmanova, A.S. (2014) Member Several national PhD committees (External organisation) Several national PhD committees
Akhmanova, A.S. (04-04-2014) Invited speaker Symposium "Life Simplified" Amsterdam (04-04-2014) The dark end of the microtubule: lessons from in vitro reconstitution
Van Battum, Eljo Y, Gunput, Rou-Afza F, Lemstra, Suzanne, Groen, Ewout J N, Yu, Ka Lou, Adolfs, Youri, Zhou, Yeping, Hoogenraad, Casper C, Yoshida, Yukata, Schachner, Melitta, Akhmanova, Anna & Pasterkamp, R Jeroen (2014). The intracellular redox protein MICAL-1 regulates the development of hippocampal mossy fibre connections. Nature Communications, 5 (17 p.).
Akhmanova, A.S. (25-06-2014) Invited speaker Gordon Conference "Signaling by Adhesion Receptors" Lewiston (25-04-2014) The role of microtubules in regulation of epithelial organization and migration in 3D environment
  2013 - Wetenschappelijke publicaties
Akhmanova, A.S. (2013) Invited speaker The British Society for Cell Biology meeting on Mechanochemical Cell Biology. Windermere, U.K. (01-01-2013) "Control of cytoskeletal organization by microtubule end-binding proteins"
Akhmanova, A.S. (2013) Invited speaker The 5th EMBO meeting Amsterdam, The Netherlands (30-08-2013 - 04-09-2013) "Control of cytoskeletal organization by microtubule end-binding proteins"
Akhmanova, A.S. (2013) Invited speaker Gordon Research conference on Molecular Membrane Biology. Proctor Academy, USA. (01-01-2013) "Control of microtubule-membrane interactions by microtubule end-binding proteins"
Larsen, J., Grigoriev, I., Akhmanova, A.S. & Pedersen, L.B. (2013). Analysis of microtubule plus-end-tracking proteins in cilia. Methods in Enzymology, 524, (pp. 105-122) (18 p.).
Molina, A., Velot, L., Ghouinem, L., Abdelkarim, M., Bouchet, B.P., Luissint, A.C., Bouhlel, I., Morel, M., Sapharikas, E., Di Tommaso, A., Honore, S., Braguer, D., Gruel, N., Vincent-Salomon, A., Delattre, O., Sigal-Zafrani, B., Andre, F., Terris, B., Akhmanova, A.S., Di Benedetto, M., Nahmias, C. & Rodrigues-Ferreira, S. (2013). ATIP3, a novel prognostic marker of breast cancer patient survival, limits cancer cell migration and slot metastatic progression by regulating microtubule dynamics. Cancer Research, 73 (9), (pp. 2905-2915) (11 p.).
Ferreira, J.G., Pereira, A.J., Akhmanova, A.S. & Maiato, H. (2013). Aurora B spatally regulates EB3 phosphorylation to coordinate daughter cell adhesion with cytokinesis. Journal of Cell Biology, 201 (5), (pp. 709-724) (16 p.).
Akhmanova, A.S. & Stearns, T. (2013). Cell architecture: putting the building blocks together. Current Opinion in Cell Biology, 25 (1), (pp. 3-5) (3 p.).
Jeffery, J.M., Grigoriev, I., Poser, I., van der Horst, A., Hamilton, N., Waterhouse, N., Bleier, J., Subramaniam, V.N., Maly, I.V., Akhmanova, A.S. & Khanna, K.K. (2013). Centrobin regulates centrosome function in interphase cells by limiting pericentriolar matrix recruitment. Cell Cycle, 12 (6), (pp. 899-906) (8 p.).
van der Vaart, Babet, van Riel, Wilhelmina E, Doodhi, Harinath, Kevenaar, Josta T, Katrukha, Eugene A, Gumy, Laura, Bouchet, Benjamin P, Grigoriev, Ilya, Spangler, Samantha A, Yu, Ka Lou, Wulf, Phebe S, Wu, Jingchao, Lansbergen, Gideon, van Battum, Eljo Y, Pasterkamp, R Jeroen, Mimori-Kiyosue, Yuko, Demmers, Jeroen, Olieric, Natacha, Maly, Ivan V, Hoogenraad, Casper C & Akhmanova, Anna (2013). CFEOM1-Associated Kinesin KIF21A Is a Cortical Microtubule Growth Inhibitor. Developmental Cell, 27 (2), (pp. 145-160) (16 p.). Copyright © 2013 Elsevier Inc. All rights reserved..
Shahbazi, M.N., Megias, D., Epifano, C., Akhmanova, A.S., Gundersen, G.G., Fuchs, E. & Perez-Moreno, M. (2013). CLASP2 interacts with p120-catenin and governs microtubule dynamics at adherens junctions. Journal of Cell Biology, 203 (6), (pp. 1043-1061) (19 p.).
Lui-Roberts, W.W., Stinchcombe, J.C., Ritter, A.T., Akhmanova, A.S., Karakesisoglou, I. & Griffiths, G.M. (2013). Cytotoxic T lymphocyte effector function is independent of nucleus-centrosome dissociation. European Journal of Immunology, 42 (8), (pp. 2132-2141) (10 p.).
van Spronsen, C.S.A.M., van Battum, E.Y., Kuijpers, M., Vangoor, V.R., rietman, M.L., Pothof, J., Gumy, L.F., van IJcken, W., Akhmanova, A.S., Pasterkamp, R.J. & Hoogenraad, C.C. (2013). Developmental and Activity-Dependent miRNA Expression Profiling in Primary Hippocampal Neuron Cultures. PLoS One, 8 (10), (pp. e74907) (1 p.).
Bulgakova, N.A., Grigoriev, I.S., Yap, A.S., Akhmanova, A.S. & Brown, N.H. (2013). Dynamic microtubules produce an asymmetric E-cadherin-Bazooka complex to maintain segment boundaries. Journal of Cell Biology, 201 (6), (pp. 887-901) (15 p.).
Hu, D.J., Baffet, A.D., Nayak, T., Akhmanova, A.S., Doye, V. & Vallee, R.B. (2013). Dynein recruitment to nuclear pores activates apical nuclear migration and mitotic entry in brain progenitor cells. Cell, 154 (6), (pp. 1300-1313) (14 p.).
Sen, I., Veprintsev, D., Akhmanova, A.S. & Steinmetz, M.O. (2013). End binding proteins are obligatory dimers. PLoS One, 8 (9), (pp. e74448) (1 p.).
Mohan, R., Katrukha, Y., Doodhi, H., Smal, I., Meijering, E., Kapitein, L.C., Steinmetz, M.O. & Akhmanova, A.S. (2013). End-binding proteins sensitize microtubules to the action of microtubule-targeting agents. Proceedings of the National Academy of Sciences of the United States of America, 110 (22), (pp. 8900-8905) (6 p.).
Berends, C.W.H., Muñoz, J., Portegijs, V.C., Schmidt, R., Grigoriev, I.S., Boxem, M., Akhmanova, A.S., Heck, A.J.R. & van den Heuvel, S. (2013). F-actin asymmetry and the endoplasmic reticulum-associated TCC-1 protein contribute to stereotypic spindle movements in the Caenorhabditis elegans embryo. Molecular Biology of the Cell, 24 (14), (pp. 2201-2215) (15 p.).
Kapitein, L.C., van Bergeijk, P.M., Lipka, J.E., Keijzer, N., Wulf, P.S., Katrukha, Y., Akhmanova, A.S. & Hoogenraad, C.C. (2013). Myosin-V opposes microtuble-based cargo transport and drives directional motility on cortical actin. Current Biology, 23 (9), (pp. 828-834) (7 p.).
Kapitein, Lukas C, van Bergeijk, Petra, Lipka, Joanna, Keijzer, Nanda, Wulf, Phebe S, Katrukha, Eugene A, Akhmanova, Anna & Hoogenraad, Casper C (2013). Myosin-V opposes microtubule-based cargo transport and drives directional motility on cortical actin. Current Biology, 23 (9), (pp. 828-34) (7 p.). Copyright © 2013 Elsevier Ltd. All rights reserved..
Akhmanova, A.S. (30-09-2013) Invited speaker Dutch meeting on Molecular and Cellular Biophysics 2013 Veldhoven, The Netherlands, NH Hoteles (21-09-2013 - 24-09-2013) Non-centrosomal microtubules are stabilized by minus-end growth dependent CAMSAP deposition
Kuijpers, M., Yu, K.L., Teuling, E., Akhmanova, A.S., Jaarsma, D. & Hoogenraad, C.C. (2013). The ALS8 protein VAPB interacts with the ER-Gogi recycling protein YIF1A and regulates membrane delivery into dendrites. EMBO Journal, 32 (14), (pp. 2056-2072) (17 p.).
van Spronsen, Myrrhe, Mikhaylova, Marina, Lipka, Joanna, Schlager, Max A, van den Heuvel, Dave J, Kuijpers, Marijn, Wulf, Phebe S, Keijzer, Nanda, Demmers, Jeroen, Kapitein, Lukas C, Jaarsma, Dick, Gerritsen, Hans, Akhmanova, Anna & Hoogenraad, Casper C (06-02-2013). TRAK/Milton motor-adaptor proteins steer mitochondrial trafficking to axons and dendrites. Neuron, 77 (3), (pp. 485-502) (18 p.). Copyright © 2013 Elsevier Inc. All rights reserved..
  2013 - Populariserende publicaties
Akhmanova, A.S. (01-04-2013) Invited speaker Medical University Innsbruck, Austria (Innsbruck, Austria) (01-01-2013) "Friends at the ends: a dynamic protein network controls the fate of microtubule tips"
Akhmanova, A.S. (01-02-2013) Invited speaker University of Turku (Turku, Finland) (01-01-2013) "Friends at the ends: a dynamic protein network controls the fate of microtubule tips".
Akhmanova, A.S. (2013) Invited speaker Gordon Research on Motile & Contractile systems (New London, USA) (01-01-2013) "Functional analysis of microtubule end-binding proteins".
Akhmanova, A.S. (2013) Invited speaker ICTS-TIFR Advanced School on Axonal Transport and Neurodegenerative Disorders (IIT-Bombay, India) (01-01-2013) "Regulation of microtubule dynamics".
Akhmanova, A.S. (01-06-2013) Invited speaker Barcelona, Spain (CRG-Center for Genomic Regulation) (01-01-2013) "Tips at the edge: regulation of microtubule dynamics at the cell coretex".
Akhmanova, A.S. (01-03-2013) Invited speaker Department of Genetics, University of Cambridge (Cambridge, U.K.) (01-01-2013) "Tips at the edge: regulation of microtubule dynamics at the cell cortex".
Akhmanova, A.S. (2013) Invited speaker 3rd Symposium on Physiology and Dynamics of Cellular Microcompartments. (Utrecht, The Netherlands.) (01-01-2013) Control of cell architecture by microtubule end-binding protiens.
Akhmanova, A.S. (2013) Invited speaker A physics of Soft & Biological Matter (Amsterdam, VU University) (01-01-2013) Molecular insights into filaments guidance
  2012 - Wetenschappelijke publicaties
Jiang, K., Toedt, G., Montenegro Gouveia, S., Davey, N.E., Hua, S., van der Vaart, B., Grigoriev, I., Larsen, J., Pedersen, L.B., Bezstarosti, K., Lince-Faria, M., Demmers, J., Steinmetz, M.O., Gibson, T.J. & Akhmanova, A.S. (2012). A proteome-wide screen for mammalian SxIP motif-containing microtubule plus-end tracking proteins. Current Biology, 22 (19), (pp. 1800-1807) (10 p.).
Akhmanova, A.S. (2012) Invited speaker Invited seminar at Charité, Universitätsmedizin Berlin, Germany (01-01-2012) A zoo at the tip: a dynamic protein network controls the fate of microtubule plus ends
Akhmanova, A.S. (2012) Member Academy of Finland (External organisation) Member
Akhmanova, A.S. (2012) Member Academy of Finland (External organisation) Grant Panel member
Akhmanova, A.S. (2012) Invited speaker Lecture at invitation at European Microscopy Congress Manchester, UK (01-01-2012) Analysis of constitutive exocytosis by high-resolution fluorescence microscopy
Splinter, D., Razafsky, D.S., Schlager, M.A., Serra-Marques, A., Grigoriev, I.S., Demmers, J., Keijzer, N., Jiang, K., Poser, I., Hyman, A.A., Hoogenraad, C.C., King, S.J. & Akhmanova, A.S. (2012). BICD2, dynactin, and LIS1 cooperate in reulating dynein recruitment to cellular structures. Molecular and Cellular Biology, 23 (21), (pp. 4226-4241) (16 p.).
Akhmanova, A.S. (2012) Editorial board member Bioarchitecture (Journal)
Akhmanova, A.S. (2012) Editorial board member BMC Cell Biology (Journal)
Louwen, R., Nieuwenhuis, E.E.S., van Marrewijk, L., Horst, D., de Ruiter, L., Heikema, A.P., van Wamel, W.J., Wagenaar, J.A., Endtz, H.P., Samsom, J.N., van Baarlen, P., Akhmanova, A.S. & van Belkum, A. (2012). Campylobacter jejuni translocation across intestinal epithelial cells is facilitated by ganglioside-like lipooligosaccharide structures. Infection and Immunity, 80 (9), (pp. 3307-3318) (12 p.).
Ratheesh, A., Gomez, G.A., Priya, R., Verma, S., Kovacs, E.M., Jiang, K., Brown, N.H., Akhmanova, A.S., Stehbens, S.J. & Yap, A.S. (2012). Centralspindlin and α-catenin regulate Rho signalling at the epithelial zonula adherens. Nature Cell Biology, 14 (8), (pp. 818-828) (11 p.).
Akhmanova, A.S. (2012) Editorial board member Current Biology (Journal)
Akhmanova, A.S. (2012) Editorial board member Current Opinion in Cell Biology (Journal)
Akhmanova, A.S. (2012) Editorial board member Cytoskeleton (Journal)
Akhmanova, A.S. (2012) Editorial board member Developmental Cell (Journal)
Akhmanova, A.S. (2012) Editorial board member EMBO Journal (Journal)
Akhmanova, A.S. (2012) Member EMBO Long Term Fellowship (External organisation) Member
Akhmanova, A.S. (2012) Editorial board member EMBO Reports (Journal)
Akhmanova, A.S. (2012) Member ERC starting grant (External organisation) Grant Panel member
Akhmanova, A.S. (2012) Editorial board member FASEB Journal (Journal)
Akhmanova, A.S. (2012) Invited speaker Invited seminar at University of Antwerp Àntwerp, Belgium (01-01-2012) Friends at the ends: a dynamic protein network controls the fate of microtubule plus tips
Akhmanova, A.S. (2012) Invited speaker Invited seminar at Warwick Medical School Warwick, UK (01-01-2012) Friends at the ends: a dynamic protein network controls the fate of microtubule plus tips
Akhmanova, A.S. (2012) Invited speaker Invited seminar at Temasek Life Sciences Laboratory (TLL) Singapore (01-01-2012) Friends at the ends: a dynamic protein network controls the fate of microtubule plus tips
Akhmanova, A.S. (2012) Invited speaker Invited seminar at University of Liverpool Liverpool, UK (01-01-2012) Friends at the ends: a dynamic protein network controls the fate of microtubule plus tips
Akhmanova, A.S. (2012) Editorial board member Journal of Cell Biology (Journal)
Akhmanova, A.S. (2012) Editorial board member Journal of Cell Science (Journal)
van der Vaart, B., Franker, M.A., Kuijpers, M., Hua, S., Bouchet, B.P.J., Jiang, Kai, Grigoriev, I.S., Hoogenraad, C.C. & Akhmanova, A.S. (2012). Microtubule plus-end tracking proteins SLAIN1/2 and ch-TOG promote axonal development. Journal of Neuroscience, 32 (42), (pp. 14722-14728) (7 p.).
Akhmanova, A.S. (2012) Editorial board member Molecular Biology of the Cell (Journal)
Akhmanova, A.S. (2012) Editorial board member Nature (Journal)
Akhmanova, A.S. (2012) Editorial board member Nature Cell Biology (Journal)
Akhmanova, A.S. (2012) Member Nederlandse Oganisatie voor Wetenschappelijk Onderzoek (NWO) (External organisation) Member
Akhmanova, A.S. (2012) Member Nederlandse Vereniging voor Microscopie (External organisation) Voorzitter
Akhmanova, A.S. (2012) Editorial board member PLoS One (Journal)
Akhmanova, A.S. (2012) Editorial board member Proceedings of the National Academy of Sciences of the United States of America (Journal)
Akhmanova, A.S. (2012) Invited speaker Invited lecture at Hunter Cellular Biology meeting Pokolbin, Hunter Valley, Australia (01-01-2012) Regulation of microtubule dynamics at the cell cortex
Buey, R.M., Sen, I., Kortt, O., Mohan, R., Gfeller, D., Veprintsev, D., Kretzschmar, I., Scheurmann, J., Neri, D., Zoete, V., Michielin, O., de Pereda, J.M., Akhmanova, A.S., Volkmer, R. & Steinmetz, M.O. (2012). Sequence determinants of a microtubule tip localization signal (MtLS). Journal of Biological Chemistry, 287 (34), (pp. 28227-28242) (16 p.).
Akhmanova, A.S. (2012) Member Stichting voor Fundamenteel Onderzoek der Materie (FOM) (External organisation) Co-organizer Dutch meeting on Molecular and Cellular Biophysics
Akhmanova, A.S. (2012) Invited speaker Invited seminar at Paul Scherrer Institut Villigen, Switzerland (01-01-2012) Tips at the edge: Regulation of microtubule dynamics at the cell cortex
Akhmanova, A.S. (2012) Editorial board member Traffic (Journal)
Huveneers, S., Oldenburg, J., Spanjaard, E., van der Krogt, G., Grigoriev, I., Akhmanova, A.S., Rehmann, H. & de Rooij, J. (2012). Vinculin associates with endothelial VE-cadherin junctions to control force-dependent remodeling. Journal of Cell Biology, 196 (5), (pp. 641-652) (12 p.).
  2012 - Populariserende publicaties
Akhmanova, A.S. (2012) Invited speaker Tata institute of Fundamental Research (Mumbai, India) (01-01-2012) "A zoo at the tip: a dynamic protein network controls the fate of microtubule ends".
  2012 - Overige resultaten
Akhmanova, A.S. (01-02-2012). Cellulaire dynamica – beweging van begin tot het eind. (11 p.). Utrecht: Universiteit Utrecht, Aanvaarding van het ambt van hoogleraar in de ‘Cellulaire Dynamica'.
  2011 - Wetenschappelijke publicaties
Tanenbaum, M.E., Macurek, L., van der Vaart, B., Galli, M., Akhmanova, A.S. & Medema, R.H. (2011). A complex of Kif18b and MCAK promotes microtubule depolymerization and is negatively regulated by Aurora kinases. Current Biology, 21 (16), (pp. 1356-1365) (10 p.).
Tanenbaum, M.E., Akhmanova, A.S. & Medema, R.H. (2011). Bi-directional transport of the nucleus by dynein and kinesin-1. Communicative and Integrative Biology, 4 (1), (pp. 21-25) (5 p.).
Akhmanova, A.S. (2011) Editorial board member BMC Cell Biology (Journal)
Akhmanova, A.S. (2011) Editorial board member Current Biology (Journal)
Akhmanova, A.S. (2011) Editorial board member Cytoskeleton (Journal)
Akhmanova, A.S. (2011) Editorial board member Developmental Cell (Journal)
Spangler, S.A., Jaarsma, D., de Graaff, E., Wulf, P.S., Akhmanova, A.S. & Hoogenraad, C.C. (2011). Differential expression of liprin-alpha proteins in the brain suggests functional diversification. Journal of Comparative Neurology, 519 (15), (pp. 3040-3060) (21 p.).
Schroder, J.M., Larsen, J., Komarova, Y., Akhmanova, A.S., Thorsteinsson, R.I., Grigoriev, I.S., Manguso, R., Christensen, S.T., Pedersen, S.F., Geimer, S. & Pedersen, L.B. (2011). EB1 and EB3 promote cilia biogenesis by several centrosome-related mechanisms. Journal of Cell Science, 124 (Pt 15), (pp. 2539-2551) (13 p.).
Akhmanova, A.S. (2011) Editorial board member EMBO Journal (Journal)
Akhmanova, A.S. (2011) Editorial board member EMBO Reports (Journal)
Akhmanova, A.S. (2011) Editorial board member FASEB Journal (Journal)
Akhmanova, A.S. (2011) Editorial board member FEBS Letters (Journal)
Buey, R.M., Mohan, R., Leslie, K., Waltzoeni, T., Missimer, J.H., Menzel, A., Bjelic, S., Bargsten, K., Grigoriev, I.S., Smal, I., Meijering, E., Aebersold, R., Akhmanova, A.S. & Steinmetz, M.O. (2011). Insights into EB structure and the role of its C-terminal domain in discriminating microtubule tips from lattice. Molecular and Cellular Biology, 22 (16), (pp. 2912-2923) (12 p.).
Yu, K.L., Keijzer, N., Hoogenraad, C.C. & Akhmanova, A.S. (2011). Isolation of novel +TIPs and their binding partners using affinity purification techniques. Methods in Molecular Biology (pp. 293-316) (24 p.).
Akhmanova, A.S. (2011) Editorial board member Journal of Cell Biology (Journal)
Akhmanova, A.S. (2011) Editorial board member Journal of Cell Science (Journal)
Akhmanova, A.S. & Dogterom, M. (2011). Kinesins lead aging microtubules to catastrophe. Cell, 147, (pp. 966-968) (3 p.).
Akhmanova, A.S. & Steinmetz, M.O. (2011). Microtubule end binding: EBs sense the guanine nucleotide state. Current Biology, 21, (pp. R283-R285) (3 p.).
Jiang, K. & Akhmanova, A.S. (2011). Microtubule tip-interacting proteins: a view from both ends. Current Opinion in Cell Biology, 23 (1), (pp. 94-101) (8 p.).
Akhmanova, A.S. (2011) Editorial board member Molecular Biology of the Cell (Journal)
Akhmanova, A.S. (2011) Editorial board member Molecular Biology of the Cell (Journal)
Akhmanova, A.S. (2011) Editorial board member Nature Cell Biology (Journal)
Akhmanova, A.S. (2011) Editorial board member Nature Reviews Molecular Cell Biology (Journal)
Kapitein, L.C., Yau, K.W., Gouveia, S.M., van der Zwan, W.A., Wulf, P.S., Keijzer, N., Demmers, J., Jaworski, J., Akhmanova, A.S. & Hoogenraad, C.C. (2011). NMDA receptor activation suppresses microtubule growth and spine entry. Journal of Neuroscience, 31 (22), (pp. 8194-8209) (16 p.).
Kovacs, E.M., Verma, S., Ali, R.G., Ratheesh, A., Hamilton, N.A., Akhmanova, A.S. & Yap, A.S. (2011). N-WASP regulates the epithelial junctional actin cytoskeleton through a non-canonical post-nucleation pathway. Nature Cell Biology, July 24 (PMID:21785420).
Akhmanova, A.S. (2011) Editorial board member Proceedings of the National Academy of Sciences of the United States of America (Journal)
Grigoriev, I., Yu, K.L., Martinez Sanchez, E., Serra-Marquez, A., Smal, I., Meijering, E., Peränen, J., Pasterkamp, R.J., van der Sluijs, P., Hoogenraad, C.C. & Akhmanova, A.S. (2011). Rab6, Rab8, and MICAL3 cooperate in controlling docking and fusion of exocytotic carriers. Current Biology, 21 (11), (pp. 967-974) (8 p.).
Tanenbaum, M.E., Medema, R.H. & Akhmanova, A.S. (2011). Regulation of localization and activity of the microtubule depolymerase MCAK. Bioarchitecture, 1 (2), (pp. 80-87) (8 p.).
van der Vaart, B., Manatschal, C., Grigoriev, I.S., Olieric, V., Gouveia, S.M., Bjelic, S., Demmers, J., Vorobjev, I., Hoogenraad, C.C., Steinmetz, M.O. & Akhmanova, A.S. (2011). SLAIN2 links microtubule plus end-tracking proteins and controls microtubule growth in interphase. Current Biology, 21 (11), (pp. 967-974) (8 p.).
Lomakin, A.J., Kraikivski, I., Semenova, S., Ikeda, K., Zaliapin, I., tirnauer, J.S., Akhmanova, A.S. & Rodionov, V.P. (2011). Stiulation of teh CLIP-170-dependent capture of membrane organelles by microtubules through fine tuning of microtubule assembly dynamics. Molecular Biology of the Cell, 22, (pp. 4029-4037) (9 p.).
Akhmanova, A.S. (2011) Editorial board member Traffic (Journal)
  2010 - Wetenschappelijke publicaties
Splinter, D., Tanenbaum, M.E., Lindqvist, A., Jaarsma, D., Flotho, A., Yu, K.L., Grigoriev, I., Engelsma, D., Haasdijk, E.D., Keijzer, N., Demmers, J., Fornerod, M., Melchior, F., Hoogenraad, C.C., Medema, R.H. & Akhmanova, A.S. (2010). Bicaudal D2, dynein, and kinesin-1 associate with nuclear pore complexes and regulate centrosome and nuclear positioning during mitotic entry. PLoS Biology, 8 (4), (pp. e1000350) (1 p.).
Tanenbaum, M.E., Akhmanova, A.S. & Medema, R.H. (2010). Dynein at the nuclear envelope. EMBO Reports, 11 (9), (pp. 649-649) (1 p.).
  2009 - Wetenschappelijke publicaties
Jaworski, Jacek, Kapitein, Lukas C, Gouveia, Susana Montenegro, Dortland, Bjorn R, Wulf, Phebe S, Grigoriev, Ilya, Camera, Paola, Spangler, Samantha A, Di Stefano, Paola, Demmers, Jeroen, Krugers, Harm, Defilippi, Paola, Akhmanova, Anna & Hoogenraad, Casper C (15-01-2009). Dynamic microtubules regulate dendritic spine morphology and synaptic plasticity. Neuron, 61 (1), (pp. 85-100) (16 p.).
  2005 - Wetenschappelijke publicaties
Akhmanova, Anna & Hoogenraad, Casper C (2005). Microtubule plus-end-tracking proteins - mechanisms and functions. Current Opinion in Cell Biology, 17 (1), (pp. 47-54) (8 p.).
Akhmanova, A.S., Mausset-Bonnefont, A.L., van Cappellen, W., Keijzer, N., Hoogenraad, C.C., Stepanova, T., Drabek, K., van Wees, J.D., Mommaas, M., Onderwater, J., van der Meulen, H., Tanenbaum, M.E., Medema, R.H., Hoogerbrugge, J.W., Vreeburg, J., Uringa, E.J., Grootegoed, J.A., Grosveld, F. & Galjart, N. (2005). The microtubule plus-end-tracking protein CLIP-170 associates with the spermatid manchette and is essential for spermatogenesis. Genes and Development, 19 (20), (pp. 2501-15) (15 p.).
  2004 - Wetenschappelijke publicaties
Lansbergen, Gideon, Komarova, Yulia, Modesti, Mauro, Wyman, Claire, Hoogenraad, Casper C, Goodson, Holly V, Lemaitre, Régis P, Drechsel, David N, van Munster, Erik, Gadella, Theodorus W J, Grosveld, Frank, Galjart, Niels, Borisy, Gary G & Akhmanova, Anna (27-09-2004). Conformational changes in CLIP-170 regulate its binding to microtubules and dynactin localization. Journal of Cell Biology, 166 (7), (pp. 1003-14) (12 p.).
Hoogenraad, Casper C, Akhmanova, Anna, Galjart, Niels & De Zeeuw, Chris I (2004). LIMK1 and CLIP-115 - linking cytoskeletal defects to Williams syndrome. BioEssays, 26 (2), (pp. 141-50) (10 p.). Copyright 2004 Wiley Periodicals, Inc..
Boxma, B., Voncken, F., Jannink, S., van Alen, T., Akhmanova, A.S., van Weelden, S.W.H., van Hellemond, J.J., Ricard, G., Huynen, M., Tielens, A.G.M. & Hackstein, JHP (2004). The anaerobic chytridiomycete fungus Piromyces sp. E2 produces ethanol via pyruvate:formate lyase and an alcohol dehydrogenase E. Molecular Microbiology, 51, (pp. 1389-1399) (11 p.).
  2003 - Wetenschappelijke publicaties
Hoogenraad, Casper C, Wulf, Phebe, Schiefermeier, Natalia, Stepanova, Tatiana, Galjart, Niels, Small, J Victor, Grosveld, Frank, de Zeeuw, Chris I & Akhmanova, Anna (17-11-2003). Bicaudal D induces selective dynein-mediated microtubule minus end-directed transport. EMBO Journal, 22 (22), (pp. 6004-15) (12 p.).
Stepanova, Tatiana, Slemmer, Jenny, Hoogenraad, Casper C, Lansbergen, Gideon, Dortland, Bjorn, De Zeeuw, Chris I, Grosveld, Frank, van Cappellen, Gert, Akhmanova, Anna & Galjart, Niels (01-04-2003). Visualization of microtubule growth in cultured neurons via the use of EB3-GFP (end-binding protein 3-green fluorescent protein). Journal of Neuroscience, 23 (7), (pp. 2655-64) (10 p.).
  2002 - Wetenschappelijke publicaties
Matanis, Theodoros, Akhmanova, Anna, Wulf, Phebe, Del Nery, Elaine, Weide, Thomas, Stepanova, Tatiana, Galjart, Niels, Grosveld, Frank, Goud, Bruno, De Zeeuw, Chris I, Barnekow, Angelika & Hoogenraad, Casper C (2002). Bicaudal-D regulates COPI-independent Golgi-ER transport by recruiting the dynein-dynactin motor complex. Nature Cell Biology, 4 (12), (pp. 986-92) (7 p.).
Coquelle, Frédéric M, Caspi, Michal, Cordelières, Fabrice P, Dompierre, Jim P, Dujardin, Denis L, Koifman, Cynthia, Martin, Patrick, Hoogenraad, Casper C, Akhmanova, Anna, Galjart, Niels, De Mey, Jan R & Reiner, Orly (2002). LIS1, CLIP-170's key to the dynein/dynactin pathway. Molecular and Cellular Biology, 22 (9), (pp. 3089-102) (14 p.).
Voncken, F., Boxma, B., Tjaden, J., Akhmanova, A.S., Huynen, M., Verbeek, F., Tielens, A.G.M., Haferkamp, I., Ekkehard Neuhaus, H., Vogels, G., Veenhuis, M. & Hackstein, JHP (2002). Multiple origins of hydrogenosomes: functional and phylogenetic evidence from the ADP/ATP carrier of the anaerobic chytrid Neocallimastix sp. Molecular Microbiology, 44, (pp. 1441-1454) (14 p.).
Hoogenraad, Casper C, Koekkoek, Bas, Akhmanova, Anna, Krugers, Harm, Dortland, Bjorn, Miedema, Marja, van Alphen, Arjan, Kistler, Werner M, Jaegle, Martine, Koutsourakis, Manoussos, Van Camp, Nadja, Verhoye, Marleen, van der Linden, Annemie, Kaverina, Irina, Grosveld, Frank, De Zeeuw, Chris I & Galjart, Niels (2002). Targeted mutation of Cyln2 in the Williams syndrome critical region links CLIP-115 haploinsufficiency to neurodevelopmental abnormalities in mice. Nature Genetics, 32 (1), (pp. 116-27) (12 p.).
  2001 - Wetenschappelijke publicaties
Akhmanova, A.S., Hoogenraad, C.C., Drabek, K., Stepanova, T., Dortland, B., Verkerk, T., Vermeulen, W., Burgering, B.M.T., de Zeeuw, C.I., Grosveld, F. & Galjart, N. (2001). CLASPs are CLIP-115 and -170 associating proteins involved in the regional regulation of microtubule dynamics in motile fribroblasts. Cell, 104, (pp. 923-935) (13 p.).
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Gegenereerd op 2017-11-18 18:41:22
Nevenfuncties
  • Chair of the Board of the Dutch Microscopy Society (Nederlandse Vereniging voor Microscopie, NVvM, http://www.microscopie.nl) 
  • Faculty Member of the “FACULTY OF 1000 BIOLOGY” Cell Biology section.
  • Elife, Senior Editor
  • PLoS Biology, Editorial Board Member
  • Journal of Cell Science, Advisory Board Member
  • Traffic, Editorial Board Member
  • BioArchitecture, Editorial Board Member
  • Membership in national and international grant panels
Gegenereerd op 2017-11-18 18:41:22
Volledige naam
prof. dr. A.S. Akhmanova Contactgegevens
Hugo R. Kruytgebouw

Padualaan 8
Kamer O503
3584 CH  UTRECHT

Telefoonnummer direct 030 253 2328
Fax 030 253 2837
Postadres
Postbus 80.124
3508 TC    UTRECHT
Gegenereerd op 2017-11-18 18:41:22
Laatst bijgewerkt op 12-09-2016