Publicaties
2023
Wetenschappelijke publicaties
Beckerson, W. C., Krider, C., Mohammad, U. A., & de Bekker, C. (2023). 28 minutes later: investigating the role of aflatrem-like compounds in Ophiocordyceps parasite manipulation of zombie ants. Animal Behaviour, 203, 225-240. https://doi.org/10.1016/j.anbehav.2023.06.011
Will, I., Beckerson, W. C., & de Bekker, C. (2023). Using machine learning to predict protein-protein interactions between a zombie ant fungus and its carpenter ant host. Scientific Reports, 13(1), 1-16. Article 13821. https://doi.org/10.1038/s41598-023-40764-8
Will, I., Attardo, G. M., & de Bekker, C. (2023). Multiomic interpretation of fungus-infected ant metabolomes during manipulated summit disease. Scientific Reports, 13(1), 1-19. Article 14363. https://doi.org/10.1038/s41598-023-40065-0
Will, I., Linehan, S., Jenkins, D. G., & De bekker, C. (2023). Natural history and ecological effects on the establishment and fate of Florida carpenter ant cadavers infected by the parasitic manipulator Ophiocordyceps camponoti‐floridani. Functional Ecology, 37(4), 886-899. https://doi.org/10.1111/1365-2435.14224
2022
Wetenschappelijke publicaties
Araújo, J. P. M., Lebert, B. M., Vermeulen, S., Brachmann, A., Ohm, R. A., Evans, H. C., & De bekker, C. (2022). Masters of the manipulator: two new hypocrealean genera, Niveomyces (Cordycipitaceae) and Torrubiellomyces (Ophiocordycipitaceae), parasitic on the zombie ant fungus Ophiocordyceps camponoti-floridani. Persoonia: Molecular Phylogeny and Evolution of Fungi, 171-194. https://doi.org/10.3767/persoonia.2022.49.05
de Bekker, C., & Das, B. (2022). Hijacking time: How Ophiocordyceps fungi could be using ant host clocks to manipulate behavior. Parasite Immunology, 44(3), 1-10. Article e12909. https://doi.org/10.1111/pim.12909
Das, B., & de Bekker, C. (2022). Time-course RNASeq of Camponotus floridanus forager and nurse ant brains indicate links between plasticity in the biological clock and behavioral division of labor. BMC Genomics, 23(1), 1-23. Article 57. https://doi.org/10.1186/s12864-021-08282-x
2021
Wetenschappelijke publicaties
Trinh, T., Ouellette, R., & de Bekker, C. (2021). Getting lost: the fungal hijacking of ant foraging behaviour in space and time. Animal Behaviour, 181, 165-184. https://doi.org/10.1016/j.anbehav.2021.09.003
de Bekker, C., Beckerson, W. C., & Elya, C. (2021). Mechanisms behind the Madness: How Do Zombie-Making Fungal Entomopathogens Affect Host Behavior To Increase Transmission? mBio, 12(5), 1-15. Article e0187221. https://doi.org/10.1128/mBio.01872-21
Andriolli, F. S., Ishikawa, N. K., Vargas-Isla, R., Cabral, T. S., De Bekker, C., & Baccaro, F. B. (2021). Corrigendum to: “Do zombie ant fungi turn their hosts into light seekers?”. Behavioral Ecology, 32(1), 199-199. https://doi.org/10.1093/beheco/araa133
2020
Wetenschappelijke publicaties
Will, I., Das, B., Trinh, T., Brachmann, A., Ohm, R. A., & de Bekker, C. (2020). Genetic underpinnings of host manipulation by ophiocordyceps as revealed by comparative transcriptomics. G3: Genes, Genomes, Genetics, 10(7), 2275-2296. https://doi.org/10.1534/g3.120.401290
2019
Wetenschappelijke publicaties
de Bekker, C. (2019). Ophiocordyceps-ant interactions as an integrative model to understand the molecular basis of parasitic behavioral manipulation. Current Opinion in Insect Science, 33, 19-24. https://doi.org/10.1016/j.cois.2019.01.005
Westwood, M. L., O’Donnell, A. J., de Bekker, C., Lively, C. M., Zuk, M., & Reece, S. E. (2019). The evolutionary ecology of circadian rhythms in infection. Nature Ecology and Evolution, 3(4), 552-560. https://doi.org/10.1038/s41559-019-0831-4
2018
Wetenschappelijke publicaties
De Bekker, C., Will, I., Das, B., & Adams, R. M. M. (2018). The ants (Hymenoptera: Formicidae) and their parasites: Effects of parasitic manipulations and host responses on ant behavioral ecology. Myrmecological News, 28, 1-24. https://doi.org/10.25849/myrmecol.news_028:001
Gracia, E. S., De Bekker, C., Hanks, E. M., & Hughes, D. P. (2018). Within the fortress: A specialized parasite is not discriminated against in a social insect society. PLoS One, 13(2), Article e0193536. https://doi.org/10.1371/journal.pone.0193536
2017
Wetenschappelijke publicaties
de Bekker, C., Will, I., Hughes, D. P., Brachmann, A., & Merrow, M. (2017). Daily rhythms and enrichment patterns in the transcriptome of the behavior-manipulating parasite Ophiocordyceps kimflemingiae. PLoS One, 12(11), e0187170. https://doi.org/10.1371/journal.pone.0187170
Hughes, M. E., Abruzzi, K. C., Allada, R., Anafi, R., Arpat, A. B., Asher, G., Baldi, P., de Bekker, C., Bell-Pedersen, D., Blau, J., Brown, S., Ceriani, M. F., Chen, Z., Chiu, J. C., Cox, J., Crowell, A. M., DeBruyne, J. P., Dijk, D-J., DiTacchio, L., ... Hogenesch, J. B. (2017). Guidelines for Genome-Scale Analysis of Biological Rhythms. Journal of Biological Rhythms, 32(5), 380-393. https://doi.org/10.1177/0748730417728663
De Bekker, C., Ohm, R. A., Evans, H. C., Brachmann, A., & Hughes, D. P. (2017). Ant-infecting Ophiocordyceps genomes reveal a high diversity of potential behavioral manipulation genes and a possible major role for enterotoxins. Scientific Reports, 7(1), Article 12508. https://doi.org/10.1038/s41598-017-12863-w
2016
Wetenschappelijke publicaties
Hughes, D. P., Araújo, J. P. M., Loreto, R. G., Quevillon, L., de Bekker, C., & Evans, H. C. (2016). From So Simple a Beginning: The Evolution of Behavioral Manipulation by Fungi. Advances in Genetics, 94, 437-69. https://doi.org/10.1016/bs.adgen.2016.01.004
2015
Wetenschappelijke publicaties
Chetouhi, C., Panek, J., Bonhomme, L., ElAlaoui, H., Texier, C., Langin, T., de Bekker, C., Urbach, S., Demettre, E., Missé, D., Holzmuller, P., Hughes, D. P., Zanzoni, A., Brun, C., & Biron, D. G. (2015). Cross-talk in host-parasite associations: What do past and recent proteomics approaches tell us? Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases, 33, 84-94. https://doi.org/10.1016/j.meegid.2015.04.015
de Bekker, C., Ohm, R. A., Loreto, R. G., Sebastian, A., Albert, I., Merrow, M., Brachmann, A., & Hughes, D. P. (2015). Gene expression during zombie ant biting behavior reflects the complexity underlying fungal parasitic behavioral manipulation. BMC Genomics, 16(1), 620. https://doi.org/10.1186/s12864-015-1812-x
Wang, F., Krijgsheld, P., Hulsman, M., de Bekker, C., Müller, W. H., Reinders, M., de Vries, R. P., & Wosten, H. (2015). FluG affects secretion in colonies of Aspergillus niger. Antonie van Leeuwenhoek International Journal of General and Molecular Microbiology, 107(1), 225-240. https://doi.org/10.1007/s10482-014-0321-2
2014
Wetenschappelijke publicaties
De Bekker, C., Quevillon, L. E., Smith, P. B., Fleming, K. R., Ghosh, D., Patterson, A. D., & Hughes, D. P. (2014). Species-specific ant brain manipulation by a specialized fungal parasite. BMC Evolutionary Biology, 14(1), Article 166. https://doi.org/10.1186/s12862-014-0166-3
De Bekker, C., Merrow, M., & Hughes, D. P. (2014). From behavior to mechanisms: An integrative approach to the manipulation by a parasitic fungus (Ophiocordyceps unilateralis s.l.) of its host ants (Camponotus spp.). Integrative and Comparative Biology, 54(2), 166-176. https://doi.org/10.1093/icb/icu063
2013
Wetenschappelijke publicaties
de Bekker, C., Smith, P. B., Patterson, A. D., & Hughes, D. P. (2013). Metabolomics Reveals the Heterogeneous Secretome of Two Entomopathogenic Fungi to Ex Vivo Cultured Insect Tissues. PLoS One, 8(8), Article e70609. https://doi.org/10.1371/journal.pone.0070609
Wösten, H. A. B., van Veluw, G. J., de Bekker, C., & Krijgsheld, P. (2013). Heterogeneity in the mycelium: Implications for the use of fungi as cell factories. Biotechnology Letters, 35(8), 1155-1164. https://doi.org/10.1007/s10529-013-1210-x
van Veluw, G. J., Teertstra, W. R., de Bekker, A. M., Vinck, A., van der Beek, N., Muller, W. H., Arentshorst, M., van der Mei, H. C., Ram, A. F., Dijksterhuis, J., & Wösten, H. A. B. (2013). Heterogeneity in liquid shaken cultures of Aspergillus niger inoculated with melanised conidia or conidia of pigmentation mutants. Studies in Mycology, 74(1), 47-57.
Wösten, H. A. B., van Veluw, G. J., de Bekker, A. M., & Krijgsheld, P. (2013). Heterogeneity in the mycelium: implications for the use of fungi as cell factors. Biotechnology Letters, 35(8), 1155-1164.
2011
Wetenschappelijke publicaties
Vinck, A., de Bekker, C., Ossin, A., Ohm, R. A., de Vries, R. P., & Woesten, H. A. B. (2011). Heterogenic expression of genes encoding secreted proteins at the periphery of Aspergillus niger colonies. Environmental Microbiology, 13(1), 216-225. https://doi.org/10.1111/j.1462-2920.2010.02322.x
de Bekker, A. M., van Veluw, G. J., Vinck, A., & Wösten, H. A. B. (2011). Heterogeneity of Aspergillus niger microcolonies in liquid shaken cultures. Applied and Environmental Microbiology, 77(4), 1263-1267.
de Bekker, A. M., Bruning, O., Jonker, M. J., Breit, T. M., & Wösten, H. A. B. (2011). Single cell transcriptomics of neighboring hyphae of Aspergillus niger. Genome Biology, 12(8), R71.
Ohm, R. A., de Jong, J. F., de Bekker, A. M., Wösten, H. A. B., & Lugones, L. G. (2011). Transcription factor genes of Schizophyllum commune involved in regulation of mushroom formation. Molecular Microbiology, 81(6), 1433-1445. https://doi.org/10.1111/j.1365-2958
Vinck, A., de Bekker, A. M., Ossin, A., Ohm, R. A., de Vries, R. P., & Wösten, H. A. B. (2011). Heterogenic expression of genes encoding secreted proteins at the periphery of Aspergillus niger colones. Environmental Microbiology, 13(1), 216-225.
de Bekker, A. M. (2011). Hyphal heterogeneity in Aspergillus niger. [Doctoral thesis 1 (Research UU / Graduation UU), Utrecht University]. Utrecht University.
https://dspace.library.uu.nl/bitstream/handle/1874/192045/bekker.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/192045/bekker.pdf?sequence=1
2010
Wetenschappelijke publicaties
de Jong, J. F., Ohm, R. A., de Bekker, A. M., Wösten, H. A. B., & Lugones, L. G. (2010). Inactivation of ku80 in the mushroom-forming fungus Schizophyllum commune increases the relative incidence of homologous recombination. FEMS Microbiology Letters, 310(1), 91-95.
2009
Wetenschappelijke publicaties
Van Peer, A. F., De Bekker, C., Vinck, A., Wösten, H. A. B., & Lugones, L. G. (2009). Phleomycin increases transformation efficiency and promotes single integrations in schizophyllum commune. Applied and Environmental Microbiology, 75(5), 1243-1247. https://doi.org/10.1128/AEM.02162-08
de Bekker, C., Wiebenga, A., Aguilar, G., & Wösten, H. A. B. (2009). An enzyme cocktail for efficient protoplast formation in Aspergillus niger. Journal of Microbiological Methods, 76(3), 305-306. https://doi.org/10.1016/j.mimet.2008.11.001
van Peer, A. F., de Bekker, A. M., Vinck, A., Wösten, H. A. B., & Lugones, L. G. (2009). Pleomycin increases transformation efficiency and promotes single integrations in Schizophyllum commune. Applied Environmental Microbiology, 75(5), 1243-1247.
de Bekker, A. M., Wiebenga, L. A., Aguilar Osorio, J. G. D. J., & Wösten, H. A. B. (2009). An enzyme cocktail for efficent protoplast formation in Aspergillus niger. Journal of Microbiological Methods, 76(3), 305-306.
2007
Wetenschappelijke publicaties
Levin Chucrel, A. M., de Vries, R. P., Conesa, A., de Bekker, A. M., Talon, M., Menke, H. H., van Peij, N. N., & Wösten, H. A. B. (2007). Spatial differentiation in the vegetative mycelium of Aspergillus niger. Eukaryotic Cell, 6(12), 2311-2322. https://doi.org/10.1128/EC.00244-07
2006
Wetenschappelijke publicaties
Sivanathan, V., Allen, M. D., De Bekker, C., Baker, R., Arciszewska, L. K., Freund, S. M., Bycroft, M., Löwe, J., & Sherratt, D. J. (2006). The FtsK γ domain directs oriented DNA translocation by interacting with KOPS. Nature Structural and Molecular Biology, 13(11), 965-972. https://doi.org/10.1038/nsmb1158