Publicaties
2021
Wetenschappelijke publicaties
Molenaar, M. R., Yadav, K. K., Toulmay, A., Wassenaar, T. A., Mari, M. C., Caillon, L., Chorlay, A., Lukmantara, I. E., Haaker, M. W., Wubbolts, R. W., Houweling, M., Vaandrager, A. B., Prieur, X., Reggiori, F., Choudhary, V., Yang, H., Schneiter, R., Thiam, A. R., Prinz, W. A., & Helms, J. B. (2021). Retinyl esters form lipid droplets independently of triacylglycerol and seipin. Journal of Cell Biology, 220(10), 1-14. [e202011071]. https://doi.org/10.1083/jcb.202011071
2020
Wetenschappelijke publicaties
Haaker, M. W., Vaandrager, A. B., & Helms, J. B. (2020). Retinoids in health and disease: A role for hepatic stellate cells in affecting retinoid levels. Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 1865(6), [158674]. https://doi.org/10.1016/j.bbalip.2020.158674
Haaker, M. W., Kruitwagen, H. S., Vaandrager, A. B., Houweling, M., Penning, L. C., Molenaar, M. R., van Wolferen, M. E., Oosterhoff, L. A., Spee, B., & Helms, J. B. (2020). Identification of potential drugs for treatment of hepatic lipidosis in cats using an in vitro feline liver organoid system. Journal of Veterinary Internal Medicine, 34(1), 132-138. https://doi.org/10.1111/jvim.15670
2017
Wetenschappelijke publicaties
Valtolina, C., Vaandrager, A. B., Favier, R. P., Tuohetahuntila, M., Kummeling, A., Jeusette, I., Rothuizen, J., & Robben, J. H. (2017). Sex specific differences in hepatic and plasma lipid profiles in healthy cats pre and post spaying and neutering: relationship with feline hepatic lipidosis. BMC Veterinary Research, 13(1), [231]. https://doi.org/10.1186/s12917-017-1152-y
Molenaar, M. R., Vaandrager, A. B., & Helms, J. B. (2017). Some Lipid Droplets Are More Equal Than Others: Different Metabolic Lipid Droplet Pools in Hepatic Stellate Cells. Lipid Insights, 10, 1-3. https://doi.org/10.1177/1178635317747281
Tuohetahuntila, M., Molenaar, M. R., Spee, B., Brouwers, J. F., Wubbolts, R., Houweling, M., Yan, C., Du, H., VanderVen, B. C., Vaandrager, A. B., & Helms, J. B. (2017). Lysosome-mediated degradation of a distinct pool of lipid droplets during hepatic stellate cell activation. Journal of Biological Chemistry, 292(30), 12436-12448. https://doi.org/10.1074/jbc.M117.778472
Ajat, M., Molenaar, M., Brouwers, J. F. H. M., Vaandrager, A. B., Houweling, M., & Helms, J. B. (2017). Hepatic stellate cells retain the capacity to synthesize retinyl esters and to store neutral lipids in small lipid droplets in the absence of LRAT. Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 1862(2), 176-187. https://doi.org/10.1016/j.bbalip.2016.10.013
2016
Wetenschappelijke publicaties
Maidina, T., Molenaar, M. R., Spee, B., Brouwers, J. F., Houweling, M., Vaandrager, A. B., & Helms, J. B. (2016). ATGL and DGAT1 are involved in the turnover of newly synthesized triacylglycerols in hepatic stellate cells. Journal of Lipid Research, 57, 1162-1174. https://doi.org/10.1194/jlr.M066415
2015
Wetenschappelijke publicaties
Corbee, R. J., Vaandrager, A. B., Kik, M. J. L., Molenaar, M. R., & Hazewinkel, H. A. W. (2015). Cutaneous Vitamin D Synthesis in Carnivorous Species. Journal of veterinary medicine and research, 2(4), 1-4. [1031].
Valtolina, C., Vaandrager, A. B., Favier, R. P., Robben, J. H., Tuohetahuntila, M., Kummeling, A., Jeusette, I., & Rothuizen, J. (2015). No up-regulation of the phosphatidylethanolamine N-methyltransferase pathway and choline production by sex hormones in cats. BMC Veterinary Research, 11(1), [280]. https://doi.org/10.1186/s12917-015-0591-6
Tuohetahuntila, M., Spee, B., Kruitwagen, H. S., Wubbolts, R., Brouwers, J. F., van de Lest, C. H., Molenaar, M. R., Houweling, M., Helms, J. B., & Vaandrager, A. B. (2015). Role of long-chain acyl-CoA synthetase 4 in formation of polyunsaturated lipid species in hepatic stellate cells. Biochimica et Biophysica Acta, 1851(2), 220-30. https://doi.org/10.1016/j.bbalip.2014.12.003
2014
Wetenschappelijke publicaties
Corbee, R. J., Tryfonidou, M. A., Grinwis, G. C. M., Schotanus, B., Molenaar, M. R., Voorhout, G., Vaandrager, A. B., Heuven, H. C. M., & Hazewinkel, H. A. W. (2014). Skeletal and hepatic changes induced by chronic vitamin A supplementation in cats. Veterinary Journal, 202(3), 503–509. https://doi.org/10.1016/j.tvjl.2014.09.029
2013
Wetenschappelijke publicaties
Aardema, H., Lolicato, F., van de Lest, C. H. A., Brouwers, J. F., Vaandrager, A. B., van Tol, H. T. A., Roelen, B. A. J., Vos, P. L. A. M., Helms, J. B., & Gadella, B. M. (2013). Bovine cumulus cells protect maturing oocytes from increased fatty acid levels by massive intracellular lipid storage. Biology of Reproduction, 88(6), 1-15. https://doi.org/10.1095/biolreprod.112.106062
2012
Wetenschappelijke publicaties
Testerink, N., Md Ajat, M. M., Houweling, M., Brouwers, J. F. H. M., Pully, V. V., van Manen, H. W. J., Otto, C., Helms, J. B., & Vaandrager, A. B. (2012). Replacement of Retinyl Esters by Polyunsaturated Triacylglycerol Species in Lipid Droplets of HepaticStellate Cells during Activation. PLoS One, 7(4), 10.1371/journal.pone.0034945. https://doi.org/10.1371/journal.pone.0034945
2011
Wetenschappelijke publicaties
Aardema, H., Vos, P. L. A. M., Lolicato, F., Roelen, B. A. J., Knijn, H. M., Vaandrager, A. B., Helms, J. B., & Gadella, B. M. (2011). Oleic Acid Prevents Detrimental Effects of Saturated Fatty Acids on Bovine Oocyte. Biology of Reproduction, 85(1), 62-69.
2009
Wetenschappelijke publicaties
Testerink, N., van der Sanden, M. H. M., Houweling, M., Helms, J. B., & Vaandrager, A. B. (2009). Depletion of phosphatidylcholine affects ER morphology and protein traffic at the Golgi complex. Journal of Lipid Research, 50, 2182-2206.
2007
Wetenschappelijke publicaties
van de Lest, C. H. A., & Vaandrager, A. B. (2007). Mechanism of cell-mediated mineralization. Current Orthopaedics, 18, 434-443.
Westermann, C. M., de Sain-van der Velden, M. G. M., van der Kolk, J. H., Berger, R., Wijnberg, I. D., Koeman, J. P., Wanders, R. J. A., Lenstra, J. A., Testerink, N., Vaandrager, A. B., Vianey-Saban, C., Acquaviva-Bourdain, C., & Dorland, L. (2007). Equine biochemical multiple acyl-CoA dehydrogenase deficiency (MADD) as a cause of rhabdomyolysis. Molecular Genetics and Metabolism, 91(4), 362-369. https://doi.org/10.1016/j.ymgme.2007.04.010
Huitema, L. F. A., & Vaandrager, A. B. (2007). What triggers cell-mediated mineralization? Frontiers in Bioscience-Landmark, 12, 2631-2645.
Bleijerveld, O. B., Brouwers, J. F. H. M., Vaandrager, A. B., Helms, J. B., & Houweling, M. (2007). The CDP-ethanolamine pathway and phosphatidylserine decarboxylation generate different phosphatidylethanolamine molecular species. Journal of Biological Chemistry, 282, 28362-28372.
https://dspace.library.uu.nl/bitstream/handle/1874/26169/43_CDP_Bleijerveld.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/26169/43_CDP_Bleijerveld.pdf?sequence=1
Huitema, L. F. A., van Weeren, R., van Balkom, B. W. M., Visser, T., van de Lest, C. H. A., Barneveld, A., Helms, J. B., & Vaandrager, A. B. (2007). Soluble factors released by ATDC5 cells affect the formation of calcium phosphate crystals. Biochimica et Biophysica Acta-Proteins Proteomics, 1774, 1108-1117.
2006
Wetenschappelijke publicaties
Huitema, L. F. A., Vaandrager, A. B., van Weeren, P. R., Barneveld, A., Helms, J. B., & van de Lest, C. H. A. (2006). The nitric oxide donor sodium nitroprusside inhibits mineralization in ATDC5 cells. Calcified Tissue International, 78(3), 171-177.
Huitema, L. F. A., van Weeren, P. R., Barneveld, A., van de Lest, C. H. A., Helms, J. B., & Vaandrager, A. B. (2006). Iron ions derived from the nitric oxide donor sodium nitroprusside inhibit mineralization. European Journal of Pharmacology, 542, 48-53.
Slot, K. A., de Boer-Brouwer, M., Houweling, M., Vaandrager, A. B., Dorrington, J., & Teerds, K. J. (2006). Luteinizing hormone inhibits Fas-induced apoptosis in ovarian surface epithelial cell lines. Journal of Endocrinology, 188(2), 227-239.
2005
Wetenschappelijke publicaties
Mete, A., van Zeeland, Y. R. A., Vaandrager, A. B., van Dijk, J. E., Marx, J. J. M., & Dorrestein, G. M. (2005). Partial purification and characterization of ferritin from the liver and intestinal mucosa of chickens, turtledoves and mynahs. Avian Pathology, 34(5), 430-434.
Vaandrager, A. B., Hogema, B. M., & de Jonge, H. R. (2005). Molecular properties and biological functions of cGMP-dependent protein kinase II. Frontiers in Bioscience-Landmark, 10, 2150-2164.
2004
Wetenschappelijke publicaties
van de Wetering, J. K., Coenjaerts, F. E. J., Vaandrager, A. B., van Golde, L. M. G., & Batenburg, J. J. (2004). Aggregation of Cryptococcus neoformans by surfactant protein D is inhibited by its capsular component glucuronoxylomannan. Infection and Immunity, 72, 145-153.
Duijsings, D. M. J. M., Houweling, M., Vaandrager, A. B., Mol, J. A., & Teerds, K. J. (2004). Hexadecylphosphocholine causes rapid cell death in canine mammary tumour cells. European Journal of Pharmacology, 502, 185-193.
van de Wetering, J. K., van Remoortere, A., Vaandrager, A. B., Batenburg, J. J., van Golde, L. M. G., Hokke, C. H., & van Hellemond, J. J. (2004). Surfactant protein D binding to terminal alpha1-3-linked fucose residues and to Schistosoma mansoni. American Journal of Respiratory Cell and Molecular Biology, 31, 565-572.
van Eijk, M., White, M. R., Batenburg, J. J., Vaandrager, A. B., van Golde, L. M. G., Haagsman, H. P., & Hartshorn, K. L. (2004). Interactions of influenza A virus with sialic acids present on porcine surfactant protein D. American Journal of Respiratory Cell and Molecular Biology, 30, 871-879.
van der Sanden, M. H. M., Houweling, M., Duijsings, D. M. J. M., Vaandrager, A. B., & van Golde, L. M. G. (2004). Inhibition of phosphatidylcholine synthesis induces expression of the endoplasmic reticulum stress and apoptosis-related protein CCAAT/enhancer-binding protein-homologous protein (CHOP/GADD153). Biochimica et Biophysica Acta-Molecular and Cell Biology of Lipids, 1636, 99-107.
van der Sanden, M. H. M., Meems, M. H., Houweling, M., Helms, J. B., & Vaandrager, A. B. (2004). Induction of CCAAT/Enhancer-binding protein (C/EBP)-homologous protein/growth arrest and DNA damage-inducible protein 153 expression during inhibition of phosphatidylcholine synthesis is mediated via activation of a C/EBP-activating transcription factor-responsive element. Journal of Biological Chemistry, 279(50), 52007-52015.
Bleijerveld, O. B., Klein, W., Vaandrager, A. B., Helms, J. B., & Houweling, M. (2004). Control of the CDPethanolamine pathway in mammalian cells: effect of CTP:phosphoethanolamine cytidylyltransferase overexpression and the amount of intracellular diacylglycerol. Biochemical Journal, 379(3), 711-719.
2003
Wetenschappelijke publicaties
van der Sanden, M. H. M., Houweling, M., Duijsings, D. M. J. M., Vaandrager, A. B., & van Golde, L. M. G. (2003). Inhibition of phosphatidylchloline synthesis is not the primary pathway in hexadecylphosphocholine-induced apoptosis. Biochemical Journal, 369, 643-650.
van der Sanden, M. H. M., Houweling, M., van Golde, L. M. G., & Vaandrager, A. B. (2003). Inhibition of phosphatidylcholine synthesis induces expression of the endoplasmic reticulum stress and apoptosis-related protein CCAAT/enhancer-binding protein-homologous protein (CHOP/GADD153). Biochemical Journal, 369, 643-650.
Vaandrager, A. B., Hogema, B. M., Edixhoven, M., Burg, C. M., Bot, A. G. M., Klatt, P., Ruth, P., Hofmann, F., van Damme, J. M. M., Vandekerckhove, J., & de Jonge, H. R. (2003). Autophosphorylation of cGMP-dependent protein kinase type II. Journal of Biological Chemistry, 278, 28651-28658.
van Eijk, M., White, M. R., Crouch, E. C., Batenburg, J. J., Vaandrager, A. B., van Golde, L. M. G., Haagsman, H. P., & Hartshorn, K. L. (2003). Porcine pulmonary collectins show distinct interactions with influenza A viruses; role of the N-linked oligosaccharides in the carbohydrate recognition domain. Journal of Immunology, 171, 1431-1440.
ten Brinke, A. J., Posthuma, G., Batenburg, J. J., Haagsman, H. P., Ridder, A. N. J. A., van Golde, L. M. G., & Vaandrager, A. B. (2003). The transmembrane domain of surfactant protein C precursor determines the morphology of the induced membrane compartment in CHO cells. European Journal of Cell Biology, 82(6), 285-294.
2002
Wetenschappelijke publicaties
ten Brinke, A., Vaandrager, A. B., Haagsman, H. P., Ridder, A. N. J. A., van Golde, L. M. G., & Batenburg, J. J. (2002). Structural requirements for palmitoylation of surfactant protein C precursor. Biochemical Journal, 351, 663-671.
https://dspace.library.uu.nl/bitstream/handle/1874/14947/TenBrinke-Structural%2520requirements.pdf?sequence=1
https://dspace.library.uu.nl/bitstream/handle/1874/14947/TenBrinke-Structural%2520requirements.pdf?sequence=1
ten Brinke, A. J., Batenburg, J. J., Haagsman, H. P., van Golde, L. M. G., & Vaandrager, A. B. (2002). Differential effect of Brefeldin A on the palmitoylation of surfactant protein C proprotein mutants. Biochemical and Biophysical Research Communications, 290, 532-538.
Vaandrager, A. B. (2002). Structure and function of the heat-stable enterotoxin receptor/guanylyl cyclase C. Molecular and Cellular Biochemistry, 230(1-2), 73-83.
van Eijk, M., van de Lest, C. H. A., Batenburg, J. J., Vaandrager, A. B., Meschi, J., Hartshorn, K. L., van Golde, L. M. G., & Haagsman, H. P. (2002). Porcine surfactant protein D is N-glycosylated in its carbohydrate recognition domain and is assembled into differently charged oligomers. American Journal of Respiratory Cell and Molecular Biology, 26, 739-747.
Vaandrager, A. B., & Houweling, M. (2002). Effect of ceramides on phospholipid biosynthesis and its implications for apoptosis. In P. J. Quinn, & V. E. Kagan (Eds.), Subcellular Biochemistry, Vol. 36, Phospholipid metabolism in Apotosis. (pp. 207-227). Kluwer Academic/Plenum Publishers.
2001
Wetenschappelijke publicaties
ten Brinke, A. J., Batenburg, J. J., Gadella, B. M., Haagsman, H. P., Vaandrager, A. B., & van Golde, L. M. G. (2001). The juxtamembrane lysine and arginine residues of surfactant protein C precursor influence palmitoylation via effects on trafficking. American Journal of Respiratory Cell and Molecular Biology, 25, 156-163.
2000
Wetenschappelijke publicaties
Vaandrager, A. B., Bot, A. G., Ruth, P., Pfeifer, A., Hofmann, F., & De Jonge, H. R. (2000). Differential role of cyclic GMP-dependent protein kinase II in ion transport in murine small intestine and colon. Gastroenterology, 118(1), 108-14.
Vaandrager, A. B., & van Golde, L. M. G. (2000). Lung surfactant proteins A and D in innate immune defense. Biology of the Neonate, 77SI, 9-13.
1999
Wetenschappelijke publicaties
Hoenderop, J. G., Vaandrager, A. B., Dijkink, L., Smolenski, A., Gambaryan, S., Lohmann, S. M., de Jonge, H. R., Willems, P. H., & Bindels, R. J. (1999). Atrial natriuretic peptide-stimulated Ca2+ reabsorption in rabbit kidney requires membrane-targeted, cGMP-dependent protein kinase type II. Proceedings of the National Academy of Sciences of the United States of America, 96(11), 6084-9.
Gudi, T., Hong, G. K., Vaandrager, A. B., Lohmann, S. M., & Pilz, R. B. (1999). Nitric oxide and cGMP regulate gene expression in neuronal and glial cells by activating type II cGMP-dependent protein kinase. FASEB Journal, 13(15), 2143-52.
1998
Wetenschappelijke publicaties
Vaandrager, A. B., Smolenski, A., Tilly, B. C., Houtsmuller, A. B., Ehlert, E. M., Bot, A. G., Edixhoven, M., Boomaars, W. E., Lohmann, S. M., & de Jonge, H. R. (1998). Membrane targeting of cGMP-dependent protein kinase is required for cystic fibrosis transmembrane conductance regulator Cl- channel activation. Proceedings of the National Academy of Sciences of the United States of America, 95(4), 1466-71.
1997
Wetenschappelijke publicaties
Vaandrager, A. B., Bot, A. G., & De Jonge, H. R. (1997). Guanosine 3',5'-cyclic monophosphate-dependent protein kinase II mediates heat-stable enterotoxin-provoked chloride secretion in rat intestine. Gastroenterology, 112(2), 437-43.
Vaandrager, A. B., Tilly, B. C., Smolenski, A., Schneider-Rasp, S., Bot, A. G., Edixhoven, M., Scholte, B. J., Jarchau, T., Walter, U., Lohmann, S. M., Poller, W. C., & de Jonge, H. R. (1997). cGMP stimulation of cystic fibrosis transmembrane conductance regulator Cl- channels co-expressed with cGMP-dependent protein kinase type II but not type Ibeta. Journal of Biological Chemistry, 272(7), 4195-200.
Vaandrager, A. B., Edixhoven, M., Bot, A. G., Kroos, M. A., Jarchau, T., Lohmann, S., Genieser, H. G., & de Jonge, H. R. (1997). Endogenous type II cGMP-dependent protein kinase exists as a dimer in membranes and can Be functionally distinguished from the type I isoforms. Journal of Biological Chemistry, 272(18), 11816-23.
Lohmann, S. M., Vaandrager, A. B., Smolenski, A., Walter, U., & De Jonge, H. R. (1997). Distinct and specific functions of cGMP-dependent protein kinases. Trends in Biochemical Sciences, 22(8), 307-12.
1996
Wetenschappelijke publicaties
Wilson, K. T., Vaandrager, A. B., De Vente, J., Musch, M. W., De Jonge, H. R., & Chang, E. B. (1996). Production and localization of cGMP and PGE2 in nitroprusside-stimulated rat colonic ion transport. American Journal of Physiology, 270(3 Pt 1), C832-40.
Vaandrager, A. B., Ehlert, E. M., Jarchau, T., Lohmann, S. M., & de Jonge, H. R. (1996). N-terminal myristoylation is required for membrane localization of cGMP-dependent protein kinase type II. Journal of Biological Chemistry, 271(12), 7025-9.
Vaandrager, A. B., & de Jonge, H. R. (1996). Signalling by cGMP-dependent protein kinases. Molecular and Cellular Biochemistry, 157(1-2), 23-30.
1995
Wetenschappelijke publicaties
Markert, T., Vaandrager, A. B., Gambaryan, S., Pöhler, D., Häusler, C., Walter, U., De Jonge, H. R., Jarchau, T., & Lohmann, S. M. (1995). Endogenous expression of type II cGMP-dependent protein kinase mRNA and protein in rat intestine. Implications for cystic fibrosis transmembrane conductance regulator. Journal of Clinical Investigation, 96(2), 822-30. https://doi.org/10.1172/JCI118128
Draijer, R., Vaandrager, A. B., Nolte, C., de Jonge, H. R., Walter, U., & van Hinsbergh, V. W. (1995). Expression of cGMP-dependent protein kinase I and phosphorylation of its substrate, vasodilator-stimulated phosphoprotein, in human endothelial cells of different origin. Circulation Research, 77(5), 897-905.
French, P. J., Bijman, J., Edixhoven, M., Vaandrager, A. B., Scholte, B. J., Lohmann, S. M., Nairn, A. C., & de Jonge, H. R. (1995). Isotype-specific activation of cystic fibrosis transmembrane conductance regulator-chloride channels by cGMP-dependent protein kinase II. Journal of Biological Chemistry, 270(44), 26626-31.
1994
Wetenschappelijke publicaties
Vaandrager, A. B., & De Jonge, H. R. (1994). Effect of cyclic GMP on intestinal transport. Advances in Pharmacology, 26, 253-83.
Vaandrager, A. B., van der Wiel, E., Hom, M. L., Luthjens, L. H., & de Jonge, H. R. (1994). Heat-stable enterotoxin receptor/guanylyl cyclase C is an oligomer consisting of functionally distinct subunits, which are non-covalently linked in the intestine. Journal of Biological Chemistry, 269(23), 16409-15.
1993
Wetenschappelijke publicaties
Vaandrager, A. B., Schulz, S., De Jonge, H. R., & Garbers, D. L. (1993). Guanylyl cyclase C is an N-linked glycoprotein receptor that accounts for multiple heat-stable enterotoxin-binding proteins in the intestine. Journal of Biological Chemistry, 268(3), 2174-9.
Vaandrager, A. B., van der Wiel, E., & de Jonge, H. R. (1993). Heat-stable enterotoxin activation of immunopurified guanylyl cyclase C. Modulation by adenine nucleotides. Journal of Biological Chemistry, 268(26), 19598-603.
1992
Wetenschappelijke publicaties
Vaandrager, A. B., van den Berghe, N., Bot, A. G., & de Jonge, H. R. (1992). Phorbol esters stimulate and inhibit Cl- secretion by different mechanisms in a colonic cell line. American Journal of Physiology, 262(2 Pt 1), G249-56.
Vaandrager, A. B., Bot, A. G., De Vente, J., & De Jonge, H. R. (1992). Atriopeptins and Escherichia coli enterotoxin STa have different sites of action in mammalian intestine. Gastroenterology, 102(4 Pt 1), 1161-9.
Bajnath, R. B., Dekker, K., Vaandrager, A. B., de Jonge, H. R., & Groot, J. A. (1992). Biphasic increase of apical Cl- conductance by muscarinic stimulation of HT-29cl.19A human colon carcinoma cell line: evidence for activation of different Cl- conductances by carbachol and forskolin. Journal of Membrane Biology, 127(2), 81-94.
Kansen, M., Keulemans, J., Hoogeveen, A. T., Scholte, B., Vaandrager, A. B., van der Kamp, A. W., Sinaasappel, M., Bot, A. G., de Jonge, H. R., & Bijman, J. (1992). Regulation of chloride transport in cultured normal and cystic fibrosis keratinocytes. Biochimica et Biophysica Acta, 1139(1-2), 49-56.
van den Berghe, N., Vaandrager, A. B., Bot, A. G., Parker, P. J., & de Jonge, H. R. (1992). Dual role for protein kinase C alpha as a regulator of ion secretion in the HT29cl.19A human colonic cell line. Biochemical Journal, 285 ( Pt 2), 673-9.
1991
Wetenschappelijke publicaties
van den Berghe, N., Nieuwkoop, N. J., Vaandrager, A. B., & de Jonge, H. R. (1991). Asymmetrical distribution of G-proteins among the apical and basolateral membranes of rat enterocytes. Biochemical Journal, 278 ( Pt 2), 565-71.
Vaandrager, A. B., Bajnath, R., Groot, J. A., Bot, A. G., & De Jonge, H. R. (1991). Ca2+ and cAMP activate different chloride efflux pathways in HT-29.cl19A colonic epithelial cell line. American Journal of Physiology, 261(6 Pt 1), G958-65.
1990
Wetenschappelijke publicaties
Vaandrager, A. B., Ploemacher, M. C., & De Jonge, H. R. (1990). Phosphoinositide metabolism in intestinal brush borders: stimulation of IP3 formation by guanine nucleotides and Ca2+. American Journal of Physiology, 259(3 Pt 1), G410-9.
1988
Wetenschappelijke publicaties
O'Grady, S. M., DeJonge, H. R., Vaandrager, A. B., & Field, M. (1988). Cyclic nucleotide-dependent protein kinase inhibition by H-8: effects on ion transport. American Journal of Physiology, 254(1 Pt 1), C115-21.
Vaandrager, A. B., & De Jonge, H. R. (1988). A sensitive technique for the determination of anion exchange activities in brush-border membrane vesicles. Evidence for two exchangers with different affinities for HCO3- and SITS in rat intestinal epithelium. Biochimica et Biophysica Acta, 939(2), 305-14.
1986
Wetenschappelijke publicaties
Vaandrager, A. B., Ploemacher, M. C., & de Jonge, H. R. (1986). Modulation of salt permeabilities of intestinal brush-border membrane vesicles by micromolar levels of internal calcium. Biochimica et Biophysica Acta, 856(2), 325-36.
Publications before 2000 on regulation of ion transport by cyclic nucleotides
Vaandrager, A.B., Bot, A.G., Ruth, P., Pfeifer, A., Hofmann, F., and De Jonge, H.R. Differential role of cyclic GMP-dependent protein kinase II in ion transport in murine small intestine and colon. (2000) Gastroenterology 118, 108-114.
Gudi, T., Hong, G.K., Vaandrager, A.B., Lohmann, S.M., and Pilz, R.B. Nitric oxide and cGMP regulate gene expression in neuronal and glial cells by activating type II cGMP-dependent protein kinase. (1999) FASEB J. 13, 2143-2152.
Hoenderop, J.G., Vaandrager, A.B., Dijkink, L., Smolenski, A., Gambaryan, S., Lohmann, S.M., De Jonge, H.R., Willems, P.H., and Bindels, R.J. Atrial natriuretic peptide-stimulated Ca2+ reabsorption in rabbit kidney requires membrane-targeted, cGMP-dependent protein kinase type II. (1999) Proc. Natl. Acad. Sci. U. S. A 96, 6084-6089.
Vaandrager, A.B., Smolenski, A., Tilly, B.C., Houtsmuller, A.B., Ehlert, E.M., Bot, A.G.M., Edixhoven, M., Boomaars, W.E., Lohmann, S.M., and De Jonge, H.R. Membrane targeting of cGMP-dependent protein kinase is required for cystic fibrosis transmembrane conductance regulator Cl- channel activation. (1998) Proc. Natl. Acad. Sci. U. S. A 95, 1466-1471.
Vaandrager, A.B., Edixhoven, M., Bot, A.G.M., Kroos,M.A., Jarchau,T., Lohmann, S.M., Genieser, H.G., and De Jonge, H.R. Endogenous type II cGMP-dependent protein kinase exists as a dimer in membranes and can Be functionally distinguished from the type I isoforms. (1997) J. Biol. Chem. 272, 11816-11823.
Vaandrager, A.B., Bot, A.G.M., and De Jonge, H.R. Guanosine 3',5'-cyclic monophosphate-dependent protein kinase II mediates heat-stable enterotoxin-provoked chloride secretion in rat intestine. (1997) Gastroenterology 112, 437-443.
Vaandrager, A.B., Tilly, B.C., Smolenski, A., Schneider-Rasp, S., Bot,A.G.M., Edixhoven, M., Scholte, B.J., Jarchau, T., Walter, U., Lohmann, S.M., Poller, W.C., and De Jonge, H.R. cGMP stimulation of cystic fibrosis transmembrane conductance regulator Cl- channels co-expressed with cGMP-dependent protein kinase type II but not type Ibeta. (1997) J. Biol. Chem. 272, 4195-4200.
Lohmann, S.M., Vaandrager, A.B., Smolenski, A., Walter, U., and De Jonge, H.R. Distinct and specific functions of cGMP-dependent protein kinases. (1997) Trends Biochem. Sci. 22, 307-312.
Wilson, K.T., Vaandrager, A.B., De Vente, J., Musch, M.W., De Jonge, H.R., and Chang, E.B. Production and localization of cGMP and PGE2 in nitroprusside-stimulated rat colonic ion transport. (1996) Am. J. Physiol 270, C832-C840.
Vaandrager, A.B., Ehlert, E.M., Jarchau, T., Lohmann, S.M., and De Jonge, H.R. N-terminal myristoylation is required for membrane localization of cGMP-dependent protein kinase type II. (1996) J. Biol. Chem. 271, 7025-7029.
Vaandrager, A.B. and De Jonge, H.R. Signalling by cGMP-dependent protein kinases. (1996) Mol. Cell Biochem. 157, 23-30.
Draijer, R., Vaandrager, A.B., Nolte, C., De Jonge, H.R., Walter, U., and van Hinsbergh, V.W. Expression of cGMP-dependent protein kinase I and phosphorylation of its substrate, vasodilator-stimulated phosphoprotein, in human endothelial cells of different origin. (1995) Circ. Res. 77, 897-905.
French, P.J., Bijman, J., Edixhoven, M., Vaandrager, A.B., Scholte, B.J., Lohmann, S.M., Nairn, A.C., and De Jonge, H.R. Isotype-specific activation of cystic fibrosis transmembrane conductance regulator-chloride channels by cGMP-dependent protein kinase II. (1995) J. Biol. Chem. 270, 26626-26631.
Markert, T., Vaandrager, A.B., Gambaryan, S., Pohler, D., Hausler, C., Walter, U., De Jonge, H.R., Jarchau, T., and Lohmann, S.M. Endogenous expression of type II cGMP-dependent protein kinase mRNA and protein in rat intestine. Implications for cystic fibrosis transmembrane conductance regulator. (1995) J. Clin. Invest. 96, 822-830.
Vaandrager, A.B. and De Jonge, H.R. Effect of cyclic GMP on intestinal transport. (1994) Adv. Pharmacol. 26, 253-283.
Vaandrager, A.B., van der Wiel, E., Hom, M.L., Luthjens, L.H., and De Jonge, H.R. Heat-stable enterotoxin receptor/guanylyl cyclase C is an oligomer consisting of functionally distinct subunits, which are non-covalently linked in the intestine. (1994) J. Biol. Chem. 269, 16409-16415.
Vaandrager, A.B., van der Wiel, E., and De Jonge, H.R. Heat-stable enterotoxin activation of immunopurified guanylyl cyclase C. Modulation by adenine nucleotides. (1993) J. Biol. Chem. 268, 19598-19603.
Vaandrager, A.B., Schulz, S., De Jonge, H.R., and Garbers, D.L. Guanylyl cyclase C is an N-linked glycoprotein receptor that accounts for multiple heat-stable enterotoxin-binding proteins in the intestine. (1993) J. Biol. Chem. 268, 2174-2179.
Vaandrager, A.B., Bot, A.G.M., De Vente, J., and De Jonge, H.R. Atriopeptins and Escherichia coli enterotoxin STa have different sites of action in mammalian intestine. (1992) Gastroenterology 102, 1161-1169.
van den Berghe, N., Vaandrager, A.B., Bot, A.G.M, Parker, P.J., and De Jonge, H.R. Dual role for protein kinase C alpha as a regulator of ion secretion in the HT29cl.19A human colonic cell line. (1992) Biochem. J. 285 ( Pt 2), 673-679.
Vaandrager, A.B., Bajnath, R., Groot, J.A., Bot, A.G.M., and De Jonge, H.R. Ca2+ and cAMP activate different chloride efflux pathways in HT-29.cl19A colonic epithelial cell line. (1991) Am. J. Physiol 261, G958-G965.
van den Berghe, N., Nieuwkoop, N.J., Vaandrager, A.B., and De Jonge, H.R. Asymmetrical distribution of G-proteins among the apical and basolateral membranes of rat enterocytes. (1991) Biochem. J. 278, 565-571.
Vaandrager, A.B., Ploemacher,M.C., and De Jonge, H.R. Phosphoinositide metabolism in intestinal brush borders: stimulation of IP3 formation by guanine nucleotides and Ca2+. (1990) Am. J. Physiol. 259, G410-G419.