Molecular Biophysics group
We are fascinated by how biological macromolecules adopt their 3D shapes
We are fascinated by how biological macromolecules (DNA, RNA, and proteins) adopt their three-dimensional shapes, make specific interactions, can deform under external forces and torques, and undergo conformational transitions to carry out the biological functions they have evolved to do. We use a range of biophysical tools, in particular single-molecule magnetic tweezers and solution X-ray scattering, to provide insights into the structure and mechanisms of these biological machines.