Ineke Braakman

Folded wrongly
Ineke Braakman
Ineke Braakman was appointed as Professor of Cellular Protein Chemistry at Utrecht University in 2000. In her research, she focuses on the underlying mechanisms of cystic fibrosis and familial hypercholesterolemia.

Nearly all processes in our body are regulated by proteins. As the three-dimensional structure of such proteins is vital for their functioning, and one mistake can ruin the structure of the protein, that little mistake may have fatal consequences. Ineke Braakman is conducting research into the folding process of several protein models and into the consequences of erroneous folding processes.

Braakman: "In the past few years, we discovered that proteins fold differently than previously assumed. We have actually broken a dogma." 

In February 2016, Braakman received 53,000 Euros from the Muco & Friends Foundation for her research on Cystic Fibrosis. She will use the grant to investigate whether so-called helper proteins in the cell can be used as medicine for Cystic Fibrosis. Read more (in Dutch)

Ineke Braakman - Proteins (YouTube subtitles available)