Biomolecular Research

Diebolder CA, Beurskens FJ, de Jong RN, Koning RI, Strumane K, Lindorfer MA, Voorhorst M, Ugurlar D, Rosati S, Heck AJ, van de Winkel JG, Wilson IA, Koster, AJ, Taylor RP, Saphire EO, Burton DR, Schuurman J, Gros P, Parren PW.
Complement is activated by IgG hexamers assembled at the cell surface.
Science. 2014 Mar 14;343(6176):1260-3. doi: 10.1126/science.1248943. PubMed PMID: 24626930; PubMed Central PMCID: PMC4250092.
Karagöz GE, Duarte AM, Akoury E, Ippel H, Biernat J, Morán Luengo T, Radli M, Didenko T, Nordhues BA, Veprintsev DB, Dickey CA, Mandelkow E, Zweckstetter M, Boelens R, Madl T, Rüdiger SG.
Hsp90-Tau complex reveals molecular basis for specificity in chaperone action.
Cell. 2014 Feb 27;156(5):963-74. doi:10.1016/j.cell.2014.01.037. PubMed PMID: 24581495; PubMed Central PMCID:PMC4263503.
​van der Cruijsen EA, Nand D, Weingarth M, Prokofyev A, Hornig S, Cukkemane AA, Bonvin AM, Becker S, Hulse RE, Perozo E, Pongs O, Baldus M.
Importance of lipid-pore loop interface for potassium channel structure and function.
Proc Natl Acad Sci U S A. 2013 Aug 6;110(32):13008-13. doi: 10.1073/pnas.1305563110. Epub 2013 Jul 23. PubMed PMID: 23882077; PubMed Central PMCID: PMC3740848.
Dörr JM, Koorengevel MC, Schäfer M, Prokofyev AV, Scheidelaar S, van der Cruijsen EA, Dafforn TR, Baldus M, Killian JA.
Detergent-free isolation,characterization, and functional reconstitution of a tetrameric K+ channel: The power of native nanodiscs.
Proc Natl Acad Sci U S A. 2014 Dec 30;111(52):18607-12. doi: 10.1073/pnas.1416205112. Epub 2014 Dec 15. PubMed PMID: 25512535; PubMed Central PMCID: PMC4284610.
van der Zand A, Gent J, Braakman I, Tabak HF.
Biochemically distinct vesicles from the endoplasmic reticulum fuse to form peroxisomes.
Cell. 2012 Apr 13;149(2):397-409. doi: 10.1016/j.cell.2012.01.054. PubMed PMID: 22500805.
Kleizen B, Braakman I. Cell biology.
A sweet send-off.
Science. 2013 May 24;340(6135):930-1. doi: 10.1126/science.1239294. PubMed PMID: 23704559.
Benevento M, Tonge PD, Puri MC, Hussein SM, Cloonan N, Wood DL, Grimmond SM, Nagy A, Munoz J, Heck AJ.
Proteome adaptation in cell reprogramming proceeds via distinct transcriptional networks.
Nat Commun. 2014 Dec 10;5:5613. doi: 10.1038/ncomms6613. PubMed PMID: 25494451.
Peng WC, de Lau W, Forneris F, Granneman JC, Huch M, Clevers H, Gros P.
Structure of stem cell growth factor R-spondin 1 in complex with the ectodomain of its receptor LGR5.
Cell Rep. 2013 Jun 27;3(6):1885-92. doi:10.1016/j.celrep.2013.06.009. PubMed PMID: 23809763.

Environmental Biology

Oome, S., Raaymakers, T.M., Cabral, A., Samwel, S., Böhm, H., Albert, I., Nürnberger, T. and Van den Ackerveken, G. (2014).
Nep1-like proteins from three kingdoms of life act as a microbe-associated molecular pattern in Arabidopsis.
Proceedings of the National Academy of Science USA 111: 16955–16960
Luna, E., Van Hulten, M., Zhang, Y., Berkowitz, O., López, A., Pétriacq, P., Sellwood, M.A., Chen, B., Burrell, M., Van de Meene, A., Pieterse, C.M.J., Flors, V., and Ton, J. (2014).
Plant perception of β-aminobutyric acid is mediated by an aspartyl-tRNA synthetase.
Nature Chemical Biology 10: 450-456
De Wit, M., Kegge, W., Evers, J.B., Vergeer-van Eijk, M.H., Gankema, P., Voesenek, L.A.C.J. and Pierik, R. (2012).
Plant neighbor detection through touching leaf tips precedes phytochrome signals.
Proceedings of the National Academy of Science USA 109: 14705-147106.
Voesenek, L.A.C.J. and Bailey-Serres, J. (2013).
Flooding tolereance: O2 sensing and survival strategies.
Current Opinion in Plant Biology 16: 647-653.
Brouwer, P., Bräutigam, A., Külahoglu, C., Tazelaar, A.O.E., Kurz, S., Nierop, K.G.J., Van der Werf, A., Weber, A.P.M., Schluepmann, H. (2014).
Azolla domestication towards a biobased economy? New Phytologist 202: 1069–1082.
Proveniers, M.C.G. (2013). Sugars speed up the circle of life eLife 2:00625.
Li, P., Zhou, H., Shi, X., Yu, B., Zhou, Y., Chen, S., Wang, Y., Peng, Y., Meyer, R.C., Smeekens, S.C., Teng, S. (2014).
The ABI4-induced Arabidopsis ANAC060 transcription factor attenuates ABA signalling and renders seedlings sugar insensitive when present in the nucleus.
PLoS Genetics 10: e1004213

Biodynamics and Biocomplexity

van Bergeijk P, Adrian M, Hoogenraad CC, Kapitein LC.
Optogenetic control of organelle transport and positioning.
Nature 2015
The I, Ruijtenberg S, Bouchet BP, Cristobal A, Prinsen MB, van Mourik T, Koreth J, Xu H, Heck AJ, Akhmanova A, Cuppen E, Boxem M, Muñoz J, van den Heuvel S.
Rb and FZR1/Cdh1 determine CDK4/6-cyclin D requirement in C. elegans and human cancer cells.
Nature Commun. 2015
Mahonen A.P., Ten Tusscher K., Siligato R., Smetana O., Diaz-Trivino S., Salojarvi J., Wachsman G., Prasad K., Heidstra R. & Scheres B.  
PLETHORA gradient formation mechanism separates auxin responses. (2014).
Nature, 515: 125-129.
Jiang K, Hua S, Mohan R, Grigoriev I, Yau KW, Liu Q, Katrukha EA, Altelaar AF, Heck AJ, Hoogenraad CC, Akhmanova A.
Microtubule minus-end stabilization by polymerization-driven CAMSAP deposition.
Dev Cell. 2014 Feb 10;28(3):295-309.
Schneider A, Seidl MF, Snel B. 
Shared protein complex subunits contribute to explaining disrupted co-occurrence.
PLoS Comput Biol. 2013;9(7):e1003124.