Cardiovascular Tissue Regeneration

ESR project

2.5

Title of project

Vascularized organs on a chip

We offer

A 4-year PhD student position in the interdisciplinary area of regenerative medicine. Your project will focus on creating and testing microfluidic systems to mimic blood vessels and vacularized organs on a chip.

We ask

You hold a Master’s degree in biology, medical biology or tissue engineering or in a related area. You have affinity with tissue engineering and molecular techniques and thrive in a multidisciplinary research environment. Experience with cardiovascular research are of benefit.

Department

The Department of nephrology and hypertension at UMCU, group located at the regenerative medicine institute Utrecht

Description

The Cheng research group aims to develop new microfluidic systems that combines organ cells with complex vascular support to create ex vivo vascularized grafts. Current ongoing projects include blood brain barrier recreation for development of an organ on a chip –drug screening device and vascularization of the complex re-absorption and filtration units of the kidney. The group offers a PhD student position for young investigators who are interested in vascular biology and complex tissue engineering.

In this COFUND project, the selected PhD student will:

  • Optimize the current vascular microfluidic system in the lab for the support of flow of circulating cells
  • Complete the challenge of creating a functional renal re-absorption unit
  • Complete the challenge of creating a functional filtration unit
  • Optimize and explore the use of the blood brain barrier device in drug screening    

Requirements

  • You have a Master in medical biology or biology or tissue engineering
  • You have affinity with molecular techniques and microfluidics
  • Experience with tissue engineering and related techniques are of benefit

Contact person & more information

Dr. Caroline Cheng, UMC Utrecht
K.L.Cheng-2@umcutrecht.nl

RESCUE

This project is part of RESCUE, a multidisciplinary, intersectoral and interdisciplinary PhD training programme in Regenerative Medicine and Stem Cells organised by UMC Utrecht (coordinator) and Utrecht University. RESCUE is partly funded by the European Commission under Horizon 2020's Marie Skłodowska-Curie Actions COFUND scheme. There are specific requirements with regards to English language and mobility for candidates who would like to take part in this programme. More information