Publications

A part of our Pubmed indexed publications can be found here

You can also visit http://www.uu.nl/staff/Search and find individual staff members.

Below we list our peer-reviewed publications of 2021:

  1. Abbring S, Engen PA, Naqib A, Green SJ, Garssen J, Keshavarzian A, van Esch ECAM. Raw Milk-Induced Protection against Food Allergic Symptoms in Mice is Accompanied by Shifts in Microbial Community Structure. International Journal of Molecular Sciences (2021) 22: 3417
  2. Abdel-Aziz MI, Neerincx AH, Vijverberg SJH, Hashimoto S, Brinkman P, Gorenjak M, Toncheva, AA, Harner S, Brandstetter S, Wolff C, Perez-Garcia J, Hedman AM, Almqvist C, Corcuera-Elosegui P, Korta-Murua J, Sardón-Prado O, Pino-Yanes M, Potočnik U, Kabesch M, Kraneveld AD, Maitland-van der Zee AH. On Behalf of the SysPharmPediA Consortium. A System Pharmacology Multi-Omics Approach toward Uncontrolled Pediatric Asthma. Journal of Personalized Medicine (2021) 11: 484
  3. Abdel-Aziz MI, Kermani NZ, Neerincx AH, Vijverberg SJH, Guo Y, Howarth P, Dahlen SE, Djukanovic R, Sterk PJ, Kraneveld AD, Maitland-van der Zee AH, Chung KF, Adcock IM; On behalf the U-BIOPRED Consortium. Association of endopeptidases, involved in SARS-CoV-2 infection, with microbial aggravation in sputum of severe asthma. Allergy (2021) 76: 1917-1921.
  4. Abdel-Aziz MI, Brinkman P, Vijverberg SJH, Neerincx AH, Riley JH, Bates S, Hashimoto S, Kermani NZ, Chung KF, Djukanovic R, Dahlén SE, Adcock IM, Howarth PH, Sterk PJ, Kraneveld AD, Maitland-van der Zee AH. Sputum microbiome profiles identify severe asthma phenotypes of relative stability at 12 to 18 months. Journal of Allergy and Clinical Immunology (2021) 147, 123-134.
  5. Acevedo N, Alashkar Alhamwe B, Caraballo L, Ding M, Ferrante A, Garn H, Garssen J, Hii CS, Irvine J, Llinás-Caballero K, López JF, Miethe S, Perveen K, Pogge von Strandmann E, Sokolowska M, Potaczek DP, van Esch BCAM. Perinatal and Early-Life Nutrition, Epigenetics, and Allergy. Nutrients (2021) 13:724
  6. Aguilera-Lizarraga, J, Florens MV, Viola MF, Jain P, Decraecker L, Appeltans I, Cuende-Estevez M, Fabre N, Van Beek K, Perna E, Balemans D, Stakenborg N, Theofanous S, Bosmans G, Mondelaers SU, Matteoli G, Ibiza Martínez S, Lopez-Lopez C, Jaramillo-Polanco J, Talavera K, Alpizar YA, Feyerabend TB, Rodewald HR, Farre R, Redegeld FA, Si J, Raes J, Breynaert C, Schrijvers R, Bosteels C, Lambrecht N, Boyd SD, Hoh RA, Cabooter D, Nelis M, Augustijns P, Hendrix S, Strid J, Bisschops R, Reed DE, Vanner SJ, Denadai-Souza A, Wouters MM, Boeckxstaens GE. Local immune response to food antigens drives meal-induced abdominal pain. Nature (2021) 590: 151-156.
  7. Alipoor SD,Mortaz E, Varahram M, Garssen J, Adcock IM. The immunopathogenesis of neuroinvasive lesions of SARS- CoV-2 infection in COVID-19 patients. Frontiers in Neurology (2021) 12: 697079
  8. Asadpoor M, Ithakisiou GN, Henricks PAJ, Pieters R, Folkerts G, Braber S. Non-Digestible Oligosaccharides and Short Chain Fatty Acids as Therapeutic Targets against Enterotoxin-Producing Bacteria and Their Toxins. Toxins (2021) 13: 175
  9. Asadpoor M, Varasteh S, Pieters RJ, Folkerts G, Braber S. Differential effects of oligosaccharides on the effectiveness of ampicillin against Escherichia coli in vitro. PharmaNutrition (2021) 17: 100263
10. Asadpoor M, Ithakisiou GN, van Putten JPM, Pieters RJ, Folkerts G, Braber, S. Antimicrobial Activities of Alginate and Chitosan Oligosaccharides Against Staphylococcus aureus and Group B Streptococcus. Frontiers in Microbiology (2021)          12: 700605.
11. Ayechu-Muruzabal V, Xiao L, Wehkamp T, van Ark I, Hoogendoorn EJ, Leusink-Muis T, Folkerts G, Garssen J, Willemsen LEM, Van ’t Land B. A fermented milk matrix containing postbiotics supports th1-and th17-type immunity in vitro and modulates the influenza-specific vaccination response in vivo in association with altered serum galectin ratios. Vaccines (2021) 9: 254
12. Ayre E, Scholey A, White D, Devilly G, Kaufman J, Verster JC, Allen C, Benson S. The relationship between alcohol hangover severity, sleep and cognitive performance; a naturalistic study. Journal of Clinical Medicine (2021) 10: 5691
13. Baars T, Wold A, Vuitton DA; Garssen J, Berge AC. Raw Cow Milk Consumption and the Atopic March. Frontiers in Pediatrics (2021) 9: 613906
14. Balikji J, Hoogbergen MM, Garssen J, Verster JC. The Association of Irritable Bowel Complaints and Perceived Immune Fitness among Individuals That Report Impaired Wound Healing: Supportive Evidence for the Gut–Brain–Skin Axis. Gastroenterology Insights (2021) 12: 423-432
15. Benner M, Lopez-Rincon A, Thijssen S, Garssen J, Ferwerda G, Joosten I, van der Molen RG, Hogenkamp A. Antibiotic Intervention Affects Maternal Immunity During Gestation in Mice. Frontiers in Immunology (2021) 12: 685742
16. Benson S, Johnson SJ, Alford C, Scholey A, Verster JC. A Cross-Cultural Comparison of the Effects of Alcohol Mixed with Energy Drink (AMED) Consumption on Overall Alcohol Consumption and Related Consequences. International Journal of Environmental Research and Public Health (2021) 18: 7579
17. Benson S, Scholey A, Verster JC. L-cysteine and the Treatment of Alcohol Hangover: A Commentary on Eriksson et al. (2020). Alcohol and Alcoholism (2021), 56: 628-629
18. Bezemer GFG, Garssen J. TLR9 and COVID-19: A Multidisciplinary Theory of a Multifaceted Therapeutic Target. Frontiers in Pharmacology (2021) 11: 601685
19. Bosman G, Oliviera S, Simons P, Sastre Torano J, Somsen GW, Knippels L, Haselberg R, Pieters RJ, Garssen J, Knipping K. Limited Lactosylation of Beta-Lactoglobulin from Cow’s Milk Exerts Strong Influence on Antigenicity and Degranulation of Mast Cells. Nutrients (2021) 13: 1-13
20. Cai Y, Gilbert MS, Gerrits WJJ, Folkerts G, Braber S. Galacto-oligosaccharides alleviate lung inflammation by inhibiting NLRP3 inflammasome activation in vivo and in vitro. Journal of Advanced Research (2021) article in press: https://doi.org/10.1016/j.jare.2021.10.013
21. Chatchatee P, Nowak-Wegrzyn A, Lange L, Benjaponpitak S, Chong KW, Sangsupawanich P, Van Ampting M, Oude Nijhuis M, Harthoorn L, Langford J, Knol J, Knipping K, Garssen J, Trendelenburg V, Pesek R, Davis CM, Muraro A, Erlewyn-Lajeunesse M, Fox AT, Michaelis LJ, Beyer K. On behalf of the PRESTO study team. Tolerance development in cow’s-milk-allergic infants receiving amino-acid-based formula- a randomized controlled trial. Journal of Allergy and Clinical Immunology (2021) 149: 650-658
22. Chen J, Garssen J, Redegeld F. The efficacy of bortezomib in human multiple myeloma cells is enhanced by combination with omega-3 fatty acids DHA and EPA: Timing is essential. Clinical Nutrition (2021) 40: 1942-1953
23. Chen J, Zaal EA, Berkers C, Ruijtenbeek R, Garssen Jo, Redegeld FA. Omega-3 Fatty Acids DHA and EPA Reduce Bortezomib Resistance in Multiple Myeloma Cells by Promoting Glutathione Degradation Cells (2021) 10: 2287
24. Corrêa RR, Juncosa EM, Masereeuw R. Lindoso RS. Extracellular Vesicles as a Therapeutic Tool for Kidney Disease: Current Advances and Perspectives. International Journal of Molecular Sciences (2021) 22: 5787
25. da Silva Ferreira AR, van der Aa SAJ, Wehkamp T, Wardill HR, Ten Klooster JP, Garssen J, Harthoorn LF, Hartog A, Harmsen HJM, Tissing WJE, van Bergenhenegouwen J. Development of a self-limiting model of methotrexate-induced mucositis reinforces butyrate as a potential therapy. Scientific Reports (2021) 11: 22911
26. Dalil Roofchayee N, Adcock IM, Marjani M, Dezfuli NK, Varahram M, Garssen J, Mortaz E. T Helper Cell Subsets in the Pleural Fluid of Tuberculous Patients Differentiate Patients With Non-Tuberculous Pleural Effusions. Frontiers in Immunology (2021) 12: 780453
27. Faria J, Gerritsen KGF, Nguyen TQ, Mihaila SM, Masereeuw R. Diabetic proximal tubulopathy: Can we mimic the disease for in vitro screening of SGLT inhibitors? European Journal of Pharmacology (2021) 908: 174378
28. Giordano, L, Mihaila SM, Eslami Amirabadi H, Masereeuw R. Microphysiological Systems to Recapitulate the Gut–Kidney Axis. Trends in Biotechnology (2021) 39: 811-823
29. Groesen E, Slingerland CJ, Innocenti P, Mihajlovic M, Masereeuw R, Martin NI. Vancomyxins: Vancomycin-Polymyxin Nonapeptide Conjugates That Retain Anti-Gram-Positive Activity with Enhanced Potency against Gram-Negative Strains. ACS Infectious Diseases (2021) 7: 2746-2754.
30. Gunn C, Fairchild G, Verster JC, Adams Sally. The Effects of Alcohol Hangover on Response Inhibition and Attentional Bias towards Alcohol-Related Stimuli. Healthcare (Basel, Switzerland) (2021) 9: 373.
31. Gunn C, Fairchild G, Verster JC, Adams S. Does alcohol hangover affect emotion regulation capacity? Evidence from a naturalistic cross-over study design. Alcohol & Alcoholism (2021) 56: 425-432.
32. Haksar D, Asadpoo, M, Heise T, Shi J, Braber S, Folkerts G, Ballell L, Rodrigues J, Pieters RJ. Fighting Shigella by Blocking Its Disease-Causing Toxin. Journal of Medicinal Chemistry (2021) 64: 6059-6069.
33. Hameete BC, Fernández Calleja JMS, de Groot MWGDM, Oppewal TR, Tiemessen MM, Hogenkamp A, de Vries BM, Groenink L. The poly(I:C)-induced maternal immune activation model; a systematic review and meta-analysis of cytokine levels in the offspring. Brain, Behavior, and Immunity (2021), 11: 100192
34. Hayen SM, Knulst AC, Garssen J,Otten HG, Willemsen LEM. Fructo-Oligosaccharides Modify Human DC Maturation and Peanut-Induced Autologous T-Cell Response of Allergic Patients In Vitro. Frontiers in Immunology (2021) 11: 600125
35. Hendriksen PA, Garssen J, Bijlsma EY, Engels F, Bruce G, Verster JC. COVID-19 Lockdown-Related Changes in Mood, Health and Academic Functioning. European Journal of Investigation in Health, Psychology and Education (2021) 11: 1440-1461
36. Hendriksen PA, Merlo A, Garssen J, Bijlsma EY, Engels F, Bruce G, Verster JC. The impact of COVID-19 lockdown on academic functioning and mood: Data from Dutch pharmacy students, PhD candidates and post-docs. MDPI Data (2021) 6: 120. Eur J Investig Health Psychol Educ 2021 Nov 18;11(4): 1440-1461. Doi: 10.3390/ejihpe11040103.
37. Hendriksen PA, Kiani P, Garssen J, Bruce G, Verster JC. Living Alone or Together During Lockdown: Association with Mood, Immune Fitness and Experiencing COVID-19 Symptoms. Psychology Research and Behavior Management (2021) 14: 1947-1957
38. Homberg R, Adan RAH, Alenina N, Asiminas A, Bader M, Beckers T, Begg DP, Blokland A, Burger ME, van Dijk G, Eisel ULM, Elgersma Y, Englitz B, Fernandez-Ruiz A, Fitzsimons CP, van Dam A-M, Gass P, Grandjean J, Havekes R, Henckens MJAG, Herden C, Hut RA Jarrett W, Jeffrey K, Jezova D, Kalsbeek A, Kamermans M, Kas MJ, Kasri NN, Kiliaan AJ, Kolk SM, Korosi A, Kort, SM, Kozicz T, Kushne, SA, Leech K, Lesch KP, Lesscher H, Lucassen PJ, Luthi A, Ma L, Mallien AS, Meerlo P, Mejias JF, Meye FJ, Mitchell AS, Mul JD, Olcese U, González AO, Olivier JDA Pasqualetti M, Pennartz CMA, Popik P, Prickaerts J, de la Prida LM, Ribeiro S, Roozendaal B, Rossato JI, Salari A-A, Schoemaker RG, Smit AB, Vanderschuren LJMJ, Takeuchi T, van der Veen R, Smidt MP, Vyazovskiy V, Wiesmann M, Wierenga CJ, Williams B, Willuhn I, Wöhr M, Wolvekamp M, van der Zee EA, Genzel L. The continued need for animals to advance brain research. Neuron (2021) 109: 2374-2379.
39. Hufnagel K, Kromp L, Bianchini R, Afify SM, Wiederstein M, Redegeld FA, Zuvalova I, Dvorak Z, Hofstetter G, Roth-Walter F, Pacios LF, Jensen-Jarolim E. Bet v 1 from birch pollen is a hypoallergen with vitamin D3 in the pocket. Allergy (2021) 76: 3801-3804
40. Irvine AR, van Berlo D, Shekhani R, Masereeuw R. A systematic review of in vitro models of drug-induced kidney injury. In: Current Opinion in Toxicology (2021) 27: 18-26.
41. Jamalpoor A, van Gelder CAGH, Yousef Yengej FA, Zaal EA, Berlingerio SP, Veys KR, Pou Casellas C, Voskuil K, Essa K, Ammerlaan CME, Rega LR, van der Welle REN, Lilien MR, Rookmaaker MB, Clevers H, Klumperman J, Levtchenko E, Berkers CR, Verhaar MC, Altelaar M, Masereeuw R, Janssen MJ. Cysteamine–bicalutamide combination therapy corrects proximal tubule phenotype in cystinosis. EMBO Molecular Medicine (2021) 13: e13067
42. Jamalpoor A, Othman,A, Levtchenko EN, Masereeuw R, Janssen,MJ. Molecular Mechanisms and Treatment Options of Nephropathic Cystinosis. In: Trends in Molecular Medicine (2021) 27: 673-686.
43. Janbazacyabar H,van Bergenhenegouwen J, Garssen J, Leusink-Muis T, van Ark I, van Daal, MT, Folkerts G, Braber S. Prenatal and Postnatal Cigarette Smoke Exposure Is Associated With Increased Risk of Exacerbated Allergic Airway Immune Responses: A Preclinical Mouse Model. Frontiers in Immunology (2021) 12: 797376
44. Janbazacyabar H, van Daal M,Leusink-Muis T, van Ark I, Garssen J, Folkerts G, van Bergenhenegouwen J, Braber S. The Effects of Maternal Smoking on Pregnancy and Offspring : Possible Role for EGF? Frontiers in Cell and Developmental Biology (2021) 9: 797376
45. Johnson SJ, Benson S, Scholey A, Alford C, Verster JC. Risk-Taking Behavior and the Consumption of Alcohol Mixed with Energy Drink among Australian, Dutch and UK Students. International Journal of Environmental Research and Public Health (2021) 18: 5315.
46. Kamphorst K, Vlieger AM, Oosterloo BC, Waarloo S, Van Elburg RM. Higher risk of allergies at 4-6 years of age aftersystemic antibiotics in the first week of life. European Journal of Investigation in Health, Psychology (2021) 11: 1440-1461
47. Kiani P, Merlo A, Saeed HM, Benson S, Bruce G, Hoorn R, Kraneveld AD, van de Loo AJAE, Severeijns NR, Sips ASM, Scholey A, Garssen J, Verster JC. Immune fitness and the psychosocial and health consequences of the covid-19 pandemic lockdown in the Netherlands: Methodology and design of the CLOFIT study. European Journal of Investigation in Health, Psychology and Education (2021) 11: 199-218.
48. Kiani P, Scholey A, Dahl TA, McMann L, Iversen JM, Verster JC. In Vitro Assessment of the Antiviral Activity of Ketotifen, Indomethacin and Naproxen, Alone and in Combination, against SARS-CoV-2. Viruses (2021) 13: 558.
49. King J, Mihaila SM, Ahmed S, Truckenmüller R, Giselbrecht S, Masereeuw R, Carlier A. The Influence of OAT1 Density and Functionality on Indoxyl Sulfate Transport in the Human Proximal Tubule: An Integrated Computational and In Vitro Study. Toxins (2021) 13: 674
50. King J, Swapnasrita S, Truckenmüller R, Giselbrecht S, Masereeuw R, Carlier A. Modeling Indoxyl Sulfate Transport in a Bioartificial Kidney: Two-Step Binding Kinetics or Lumped Parameters Model for Uremic Toxin Clearance? Computers in Biology and Medicine (2021) 138
51. Li M, van Esch BCAM, Henricks PAJ, Garssen J, Folkerts G. IL-33 Is Involved in the Anti-Inflammatory Effects of Butyrate and Propionate on TNFα-Activated Endothelial Cells. International Journal of Molecular Sciences (2021) 22: 2447
52. Li W, Sparidans RW, Martins MLF, El-Lari M, Lebre MC, van Tellingen O, Beijnen JH, Schinkel AH. ABCB1 and ABCG2 restrict brain and testis accumulation and, alongside CYP3A, limit oral availability of the novel TRK inhibitor selitrectinib. Molecular Cancer Therapeutics 20 (2021) 1173.
53. Li W, Sparidans RW, Lebre MC, Beijnen JH, Schinkel AH. Abcb1 and abcg2 control brain accumulation and intestinal disposition of the novel ros1/trk/alk inhibitor repotrectinib, while oatp1a/1b, abcg2, and cyp3a limit its oral availability. Pharmaceutics (2021) 13: 1-17
54. Lian P, Braber S, Varasteh S, Wichers HJ, Folkerts G. Hypoxia and heat stress affect epithelial integrity in a Caco-2/HT-29 co-culture. Scientific Reports (2021) 11: 13186
55. Liu M, Thijssen S, van Nostrum CF, Hennink WE, Garssen J, Willemsen LEM. Inhibition of cow’s milk allergy development in mice by oral delivery of β-lactoglobulin-derived peptides loaded PLGA nanoparticles is associated with systemic whey-specific immune silencing. Clinical and Experimental Allergy (2021) 52: 137-148
56. Lopez-Rincon A, Tonda A, Mendoza-Maldonado Lucero, Mulders DGJC, Molenkamp R, Perez-Romero CA Claassen E, Garssen J, Kraneveld AD. Classification and specific primer design for accurate detection of SARS-CoV-2 using deep learning. Scientific Reports (2021) 11: 947
57. Mackus M, van de Loo AJAE, van den Bogaard WJM, Korte-Bouws GAH, Garssen J, Verster JC. The 5HTOL/5HIAA Ratio as a Biomarker of Alcohol Hangover. Journal of Clinical Medicine (2021) 10: 4241
58. Mantas, I, Millan MJ, Di Cara B, Groenink L, Veiga S, Cistarelli L, Brocco M, Bertrand M, Svenningsson P, Zhang X. Trace amine-associated receptor 1 contributes to diverse functional actions of o-phenyl-iodotyramine in mice but not to the effects of monoamine-based antidepressants. In: International Journal of Molecular Sciences (2021) 22: 8907
59. Merlo A, Hendriksen PA, Garssen J, Bijlsma EY, Engels F, Bruce G, Verster JC. Transition to Online Education during the COVID-19 Pandemic: Impact of Changes in Alcohol Consumption and Experiencing Hangovers on Academic Functioning. Journal of Clinical Medicine (2021) 10: 5332
60. Merlo A, Hendriksen PA, Severeijns NR, Garssen J, Bruce G, Verster JC. Alcohol Consumption Patterns during COVID-19 Lockdown and Their Relationship with Perceived Immune Fitness and Reported COVID-19 Symptoms. Healthcare (2021) 9: 1039
61. Merlo A, Severeijns NR, Benson S, Scholey A, Garssen J, Bruce G, Verster JC. Mood and Changes in Alcohol Consumption in Young Adults during COVID-19 Lockdown: A Model Explaining Associations with Perceived Immune Fitness and Experiencing COVID-19 Symptoms. International Journal of Environmental Research and Public Health (2021) 8: 10028
62. Metselaar PI, Hos C, Welting O, Bosch JA, Kraneveld AD, de Jonge WJ, Te Velde AA. Ambiguity about Splicing Factor 3b Subunit 3 (SF3B3) and Sin3A Associated Protein 130 (SAP130). Cells (2021) 10: 1-8.
63. Metselaar PI, Mendoza-Maldonado L, Li Yim AYF, Abarkan I, Henneman P, te Velde AA, Schönhuth A, Bosch JA, Kraneveld AD, Lopez-Rincon A. Recursive ensemble feature selection provides a robust mRNA expression signature for myalgic encephalomyelitis/chronic fatigue syndrome. Scientific Reports (2021) 11: 4541
64. Mihajlovic M, Krebber MM, Yang Y, Ahmed S, Lozovanu V, Andreeva D, Verhaar MC, Masereeuw R. Protein-Bound Uremic Toxins Induce Reactive Oxygen Species-Dependent and Inflammasome-Mediated IL-1β Production in Kidney Proximal Tubule Cells. Biomedicines (2021) 9: 1326
65. Moerings BGJ, de Graaff P, Furber M, Witkamp RF, Debets R, Mes JJ, van Bergenhenegouwen J, Govers C. Continuous Exposure to Non-Soluble β-Glucans Induces Trained Immunity in M-CSF-Differentiated Macrophages. Frontiers in Immunology (2021) 12: 672796
66. Morales-Ferré C, Azagra-Boronat I, Massot-Cladera M, Tims S, Knipping K, Garssen J, Knol J, Franch À, Castell M, Rodríguez-Lagunas MJ, Pérez-Cano FJ. Effects of a Postbiotic and Prebiotic Mixture on Suckling Rats' Microbiota and Immunity. Nutrients (2021) 13: 2975
67. Mortaz E, Bezemer G, Alipoor SD, Varahram M, Mumby S, Folkerts G, Garssen, J, Adcock IM. Nutritional Impact and Its Potential Consequences on COVID-19 Severity. Frontiers in Nutrition (2021) 8: 698617
68. Mortaz E,Tabarsi P, Jamaati H, Dalil Roofchayee N, Dezfuli NK, Hashemian SM, Moniri A, Marjani M, Malekmohammad M, Mansouri D, Varahram M, Folkerts G, Adcock IM. Increased Serum Levels of Soluble TNF-α Receptor Is Associated with ICU Mortality in COVID-19 Patients. In: Frontiers in Immunology (2021) 12: 592727
69. Oost MJ, Velkers FC, Kraneveld AD, Venema K. Development of the in vitro Cecal Chicken ALIMEntary tRact mOdel-2 to Study Microbiota Composition and Function. In: Frontiers in Microbiology (2021) 12: 1-12
70. Opitz A, Ghin F, Hubert J, Verster JC, Beste C, Stock AK. Alcohol intoxication, but not hangover, differentially impairs learning and automatization of complex motor response sequences. In: Scientific Reports (2021) 11: 12539.
71. O'Reilly D, Dorodnykh D, Avdeenko NV, Nekliudov NA, Garssen J, Elolimy AA, Petrou L, Simpson MR, Yeruva L, Munblit D. Perspective: The Role of Human Breast-Milk Extracellular Vesicles in Child Health and Disease. In: Frontiers in Nutrition (2021) 12: 59-70
72. Pelgrim CE, van den Heuvel JM, Folkerts G, Garssen J, Maitland-van der Zee AH, Kraneveld AD. Higher prescription of antidepressants and/or anxiolytics among chronic obstructive pulmonary disease patients. In: Therapeutic Advances in Respiratory Disease (2021) 15: 1-9
73. Peralta-Marzal LN, Prince N, Bajic D, Roussin L, Naudon L, Rabot S, Garssen J, Kraneveld AD, Perez-Pardo Paula. The impact of gut microbiota-derived metabolites in autism spectrum disorders. In: International Journal of Molecular Sciences (2021) 22: 10052
74. Perez-Pardo P, Grobben Y, Willemsen-Seegers N, Hartog M, Tutone M, Muller M, Adolfs Y, Pasterkamp RJ, Vu-Pham D, van Doornmalen AM, van Cauter F, de Wit J, Gerard Sterrenburg J, Uitdehaag JCM, de Man J, Buijsman RC, Zaman GJR, Kraneveld AD. Pharmacological validation of TDO as a target for Parkinson’s disease. FEBS Journal (2021) 288: 4311-4331
75. Pou Casellas C, Jansen K, Rookmaaker MB, Clevers H, Verhaar MC, Masereeuw R. Regulation of Solute Carriers OCT2 and OAT1/3 in the Kidney : A Phylogenetic, Ontogenetic and Cell Dynamic Perspective. In: Physiological Reviews (2021) 103: 933-1024
76. Retmana IA, Loos NHC Schinkel AH, Beijnen JH, Sparidans RW. Quantification of KRAS inhibitor sotorasib in mouse plasma and tissue homogenates using liquid chromatography-tandem mass spectrometry. In: Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences (2021) 1174: 122718
77. Retmana A, Beijnen JH, Sparidan RW. Chromatographic bioanalytical assays for targeted covalent kinase inhibitors and their metabolites. In: Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences (2021) 1162, 122466
78. Richards LB, Li M, Folkerts G, Henricks PAJ, Garssen J, Van Esch BCAM. Butyrate and Propionate Restore the Cytokine and House Dust Mite Compromised Barrier Function of Human Bronchial Airway Epithelial Cells. International Journal of Molecular Sciences (2021) 22: 65
79. Rood JJM, Jamalpoor A, van Hoppe S, van Haren MJ, Wasmann RE, Janssen MJ, Schinkel AH, Masereeuw R, Beijnen JH, Sparidans RW. Extrahepatic metabolism of ibrutinib. In: Investigational New Drugs (2021) 39: 1-14.
80. Rood JJM, Sastre Toraño J, Somovilla VJ, Beijnen JH, Sparidans RW. Bioanalysis of erlotinib, its O-demethylated metabolites OSI-413 and OSI-420, and other metabolites by liquid chromatography-tandem mass spectrometry with additional ion mobility identification. In: Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences (2021) 1166, 122554.
81. Roth-Walter F, Adcock, IM, Benito-Villalvilla C, Bianchini R, Bjermer L, Boyman O, Caramori G, Cari L, Chung KF, Diamant Z, Eguiluz-Gracia I, Knol EF, Kolios Aga, Levi-Schaffer F, Nocentini G, Palomares O, Redegeld F, Van Esch B, Stellato C. Immune modulation via T regulatory cell enhancement : disease-modifying therapies for autoimmunity and their potential for chronic allergic and inflammatory diseases - An EAACI position paper of the Task Force on Immunopharmacology (TIPCO). In: Allergy (2021) 76: 90-113.
82. Roth-Walter F, Afify SM, Pacios Luis F, Blokhuis BR, Redegeld F, Regner A, Petje LM, Fiocchi, Untersmayr E, Dvorak Z, Hufnagl K, Pali-Schöll I, Jensen-Jarolim E. Cow's milk protein β-lactoglobulin confers resilience against allergy by targeting complexed iron into immune cells. In: Journal of Allergy and Clinical Immunology (2021) 147: 321-344.
83. Saeed HM, Sips ASM, Owen LJ, Verster JC. The Relationship between Pain Sensitivity, Pain Catastrophizing and Hangover Severity. In: International Journal of Environmental Research and Public Health (2021) 18: 2047.
84. Schot WD, Hegeman MA, Ten Broeke T, Valentijn FA, Meijerman I, Prins FJ, Dictus WJAG, Bovenschen N. A novel undergraduate biomedical laboratory course concept in synergy with ongoing faculty research. Biochemistry and Molecular Biology Education (2021) 49: 758-767
85. Seyed Toutounchi N, Braber S, van’t Land B, Thijssen S, Garssen J, Kraneveld AD, Folkerts G, Hogenkamp A. Exposure to Deoxynivalenol During Pregnancy and Lactation Enhances Food Allergy and Reduces Vaccine Responsiveness in the Offspring in a Mouse Model. In: Frontiers in Immunology (2021) 12: 797152
86. Seyed Toutounchi N, Braber S, Hogenkamp A, Varasteh S, Cai Y, Wehkamp T, Tims S, Leusink-Muis T, van Ark I, Wiertsema S, Stahl B, Kraneveld AD, Garssen J, Folkerts G, Van’t Land, B. Human milk oligosaccharide 3′-gl improves influenza-specific vaccination responsiveness and immunity after deoxynivalenol exposure in preclinical models. Nutrients (2021) 13: 3190 87.
Slob EMA, Brew BK, Vijverberg SJH, Dijs T, van Beijsterveldt CEM, Koppelman GH, Bartels M, Dolan CV, Larsson H, Lundström S, Lichtenstein P, Gong T, Maitland-van der Zee AH, Kraneveld AD, Almqvist C, Boomsma DI. Early-life antibiotic use and risk of attention-deficit hyperactivity disorder and autism spectrum disorder: results of a discordant twin study. Int J Epidemiol (2021) 50: 475-484.
88. Smits M, Nooijen I, Redegeld F, de Jong A, Le TM, Knulst A, Houben G, Verhoeckx K. Digestion and Transport across the Intestinal Epithelium Affects the Allergenicity of Ara h 1 and 3 but Not of Ara h 2 and 6. In: Molecular Nutrition & Food Research (2021) 65: e2000712
89. Szklany K, Engen P, Naqib A, Green SJ, Keshavarzian A, Lopez Rincon A, Siebrand C, Diks MAP, van de Kaa M, Garssen J, Knippels LMJ, Kraneveld AD. Dietary supplementation throughout life with prebiotics and/or n-3 poly-unsaturated fatty acids in healthy mice modulates gut-immune system-brain axis. Nutrients (2021) 14: 173.
90. Taranta A, Elmonem MA, Bellomo F, Leo E De, Boenzi S, Janssen MJ, Jamalpoor A, Cairoli S, Pastore A, Stefanis C De, Colucci M, Rega LR, Giovannoni I, Francalanci P, van den Heuvel LP, Dionisi-Vici C, Goffredo BM, Masereeuw R, Levtchenko E, Emma F. Benefits and Toxicity of Disulfiram in Preclinical Models of Nephropathic Cystinosis. Cells (2021) 10: 1-16
91. van Berlo D, van de Steeg E, Amirabadi HE, Masereeuw R. The potential of multi-organ-on-chip models for assessment of drug disposition as alternative to animal testing. Current Opinion in Toxicology (2021) 27: 8-17
92. van Daal MT, Folkerts G, Garssen J, Braber S. Pharmacological Modulation of Immune Responses by Nutritional Components. Pharmacological Reviews (2021) 73: 198-232.
93. van de Loo AJAE, Raasveld SJ, Hogewoning A, Zeeuw R de, Bosma ER, Bouwmeester NH, Lukkes M, Knipping K, Mackus M, Kraneveld AD, Brookhuis KA. Garssen J, Scholey A, Verster JC. Immune Responses after Heavy Alcohol Consumption : Cytokine Concentrations in Hangover-Sensitive and Hangover-Resistant Drinkers. Healthcare (2021) 9: 35
94. van der Sluiszen NNJJM, Vermeeren A, van Dijken JH, van de Loo, AJAE, Veldstra JL, de Waard D, Verster JC, Brookhui, KA, Ramaekers JG. Driving performance and neurocognitive skills of long-term users of sedating antidepressants. Human PsychopharmacologyClinical and Experimental (2021) 36: 1-12
95. van Genderen AM, Jansen K, Kristen M, van Duijn JH, Li Y, Schuurmans CCL, Malda J, Vermonden T, Jansen J, Masereeuw R, Castilho M. Topographic Guidance in Melt-Electrowritten Tubular Scaffolds Enhances Engineered Kidney Tubule Performance. Frontiers in Bioengineering and Biotechnology (2021) 8: 617364
96. van Houwelingen A, Kusurkar RA, Engels Ferdi. Evaluation of a Multidisciplinary Bachelor Course on Pain with Autonomy-Supportive Teaching Strategies through the Lens of Self-Determination Theory. Pharmacy (2021) 9: 66
97. van Sadelhoff JHJ, Siziba LP, Buchenauer L, Mank M, Wiertsema SP, Hogenkamp A, Stahl B, Garssen J, Rothenbacher D, Genuneit J. Free and total amino acids in human milk in relation to maternal and infant characteristics and infant health outcomes: The ulm spatz health study. In: Nutrients (2021) 13: 2009
98. Verstegen REM, Kostadinova AI, Merenciana Z, Garssen J, Folkerts G, Hendriks RW, Willemsen LEM. Dietary Fibers: Effects, Underlying Mechanisms and Possible Role in Allergic Asthma Management. Nutrients (2021) 13:4153
99. Verster JC, Sandalova E, Garssen J, Bruce G. The Use of Single-Item Ratings Versus Traditional Multiple-Item Questionnaires to Assess Mood and Health. European Journal of Investigation in Health, Psychology and Education (2021) 11:183-198
100. Verster JC, Scholey A, Dahl TA, Iversen JM. A Comparison of the Antinociceptive Properties of SJP-005 and Morphine in Rats. In: Pharmaceutics (2021) 13: 243
101. Verster JC, Scholey A, Dahl TA, Iversen JM. Functional observation after morphine withdrawal: effects of SJP-005. Psychopharmacology (2021), 238: 1449-1460
102. Verster JC, Severeijns NR, Sips ASM, Saeed HM, Benson S, Scholey A, Bruce G. Corrigendum to: Alcohol Hangover Across the Lifespan: Impact of Sex and Age. Alcohol and Alcoholism (2021) 56: 633
103. Verster JC, van Rossum CJI, Scholey A. Unknown safety and efficacy of alcohol hangover treatments puts consumers at risk. Addictive Behaviors (2021) 122: 107029
104. Verster JC, Arnoldy L, van de Loo AJAE, Kraneveld AD, Garssen J, Scholey A. The impact of having a holiday or work in Fiji on perceived immune fitness. Tourism and Hospitality (2021) 2: 95–112
105. Verster JC, Severeijns NR, Sips ASM, Saeed HM, Benson S, Scholey A, Bruce G. Alcohol hangover across the lifespan: impact of sex and age. Alcohol and Alcoholism (2021) 56: 589-598
106. Ververs FA; Engelen SE; Nuboer R; Vastert B; van der Ent CK; Van't Land B; Garssen J; Monaco C; Boes M; Schipper HS. Immunometabolic factors in adolescent chronic disease are associated with Th1 skewing of invariant Natural Killer T cells. Scientific Reports (2021) 11:20082
107. Vinckenbosch FRJ, Vermeeren A, Vuurman EFPM, van der Sluiszen NNJJM, Verster JC, van de Loo AJAE, van Dijken JH, Veldstra JL, Brookhuis KA, De Waard D, Ramaekers JoG. An explorative approach to understanding individual differences in driving performance and neurocognition in long-term benzodiazepine users. Human Psychopharmacology-Clinical and Experimental (2021) 36: e2778.
108. Vinken M, Benfenati E, Busquet F, Castell J, Clevert D-A, de Kok T, Dirven H, Fritsche E, Geris L, Gozalbes R, Hartung T, Jennen D, Jover R, Kandarova H, Kramer N, Krul C, Luechtefeld T, Masereeuw R, Roggen E, Schaller S, Vanhaecke T, Yang C, Piersma AH. Safer chemicals using less animals: kick-off of the European ONTOX project. Toxicology (2021) 458: 1-7
109. Vlahou A, Hallina, D, Apweiler R, Argiles A, Beige J, Benigni A, Bischoff R, Black PC, Boehm F, Céraline J, Chrousos GP, Delles C, Evenepoel P, Fridolin I, Glorieux G, van Gool AJ, Heidegger I, Ioannidis JPA, Jankowski J, Jankowski V, Jeronimo C, KAM, Masereeuw R, Mayer G, Mischak H, Ortiz A, Remuzzi G, Rossing P, Schanstra JP, Schmitz-Dräger BJ, Spasovski G, Staessen JA, Stamatialis D, Stenvinkel P, Wanner C, Williams SB, Zannad F, Zoccali C, Vanholder R. Data Sharing Under the General Data Protection Regulation : Time to Harmonize Law and Research Ethics?. Hypertension. (2021) 77: 1029-1035
110. Vormann MK, Vriend J, Lanz HL, Gijzen L, van den Heuvel A, Hutter S, Joore J, Trietsch SJ, Stuut C, Nieskens TTG, Peters JGP, Ramp D, Caj M, Russel FGM, Jacobsen B, Roth A, Lu S, Polli JW, Naidoo AA, Vulto P, Masereeuw R, Wilmer MJ, Suter-Dick L. Implementation of a Human Renal Proximal Tubule on a Chip for Nephrotoxicity and Drug Interaction Studies. In: Journal of Pharmaceutical Sciences (2021) 110: 1601-161.