"Predicting, modelling and understanding biomolecular interactions in the post-genomic era"

Research within the computational structural biology group focuses on the development of reliable bioinformatics and computational approaches to predict, model and dissect biomolecular interactions at atomic level. For this, bioinformatics data, structural information and available biochemical or biophysical experimental data are combined to drive the modelling process. This is implemented and further developed in the widely used HADDOCK software for the modelling of biomolecular complexes.
By following a holistic approach integrating various experimental information sources with computational structural biology methods we aim at obtaining a comprehensive description of the structural and dynamic landscape of complex biomolecular machines, adding the structural dimension to interaction networks and opening the route to systematic and genome-wide studies of biomolecular interactions.

Major research interests

Biomolecular interactions; docking; structure and dynamics; biomolecular modelling; NMR spectroscopy; computational structural biology.

Short CV
List of publications
VICI 2006 laureate
Research highlights

For more information please go to the website of the Bonvin lab