Advanced chemistry sci 322, university college utrecht

this course offers first of all an advanced treatment of a number of important subjects in chemistry related to chemical structure and chemical processes. X-ray crystallography and NMR spectroscopy are widely used to determine the structure of molecules up to the level of complex biological macromolecules such as proteins. Synthesis routes used to produce chemicals (especially in industry) are extremely dependent on catalysis as an all-important way to enable or facilitate the synthetic process of producing chemical compounds. the occurrence of electronic and photonic processes is a key ingredient for the application of chemical substances in materials science. In the second part of the course a literature study and research project will be executed within a specific research group.



Dr. G.J. Vroege

  • Dr. A.M.J.J. Bonvin NMR Spectroscopy
  • Dr. C. de Mello Donega (electronic and photonic processes)
  • Dr. R.J.M. Klein Gebbink (catalysis)

esides the specific knowledge offered in this course, students will acquire a feeling for and an operational knowledge of the qualitative and quantitative approach in chemistry and will be able to address actual problems in this field in a creative way. After this course they will be able to read papers in basic scientific journals and more advanced textbooks and solve problems in practical situations.B


The course will cover 200 hours. During weeks 1-8 a lecture/meeting of 2 hours will be held twice a week, during and outside which there is opportunity for (guided) self-study, exercises and demonstrations. At least 4 additional hours are needed to prepare for each lecture/meeting. The 3 different topics (NMR spectroscopy, catalysis, electronic and photonic processes) will each be treated by an expert in the field.

In weeks 10-14 each student participates in a research project on a subject chosen (forming groups of at least 2 students). The research topic will be studied within one of the research groups at De Uithof, both theoretically (leading to an essay) and experimentally (leading to a research report). THIS REQUIRES ONE FULL WEDNESDAY EACH WEEK (instead of the usual meetings). In week 15 the course will be concluded with a symposium at which each student presents his project to the others.


During the first part of the course taught assigned problems must be handed in and will be graded (with a weight of 5 % for the final grade); for the NMR part, this will be replaced by one minute papers (see the description of the NMR course for more details). Each topic will be concluded with a written examination (15 % each). The project in the second part will be judged (individually) on the basis of the practical work, essay and experimental report (30 %) as well as the symposium presentation (10 %).


The NMR part of the course will be given on the basis of the following book:

  • NMR spectroscopy (obligatory!): P.J. Hore. Nuclear Magnetic Resonance. Oxford Chemistry Primers. Oxford, Oxford University Press 1995, ISBN: 0-19-855682-9) and reader
  • Catalysis: R.A. van Santen et al. Catalysis: An Integrated Approach. 2nd, revised, and enlarged edition (Amsterdam [etc.], Elsevier, 1999, ISBN: 0-444-50593-8)
  • Electronic and photonic processes: D. F. Shriver and P. W. Atkins. Inorganic chemistry 3rd ed. (Oxford, Oxford U.P., 1999, ISBN: 0-19-850330-x) and McQuarrie and Simon Physical Chemistry

Additional material will be handed out during the course as well as references to other literature.