Advanced Course "From Data to Structures"

Advanced Course

"From Data to Structures"
June 10-21 2002, Utrecht Nijmegen

 

The Bijvoet-NSR Research Alliance (BNRA) organizes from June 10th to June 21st 2002 a course dealing with the structure determination of proteins and DNA from nuclear magnetic resonance spectroscopy data.

The course is given partly in Utrecht (first week) and in Nijmegen (second week). Participation is free for members of the groups of the Bijvoet-NSR Research Alliance. The registration fee for participants from other universities amounts to Euro 350.- and for others to Euro 1000.-. The number of participants is limited to 16.

Course contents 

The courses consists of lectures (in the morning) and practical sessions (in the afternoon). Topics such as data processing and analysis and structure determination and validation of biomolecules will be discussed. The acquired knowledge will be directly applied in the practical sessions. During those, the structure of a small protein based on NMR data will be calculated following various protocols for data conversions and structure calculations. The results will be presented the last day. 

Lecturers:

  • Prof. Dr. Rolf Boelens Utrecht University
  • Dr. Alexandre M.J.J. Bonvin Utrecht University
  • Dr. Martin Blackledge IBS Grenoble
  • Dr. Hans A. Heus University of Nijmegen
  • Dr. Michael Nilges EMBL Heidelberg
  • Prof. Dr. Cees W. Hilbers University of Nijmegen
  • Dr. Chris A.E.M Spronk CMBI Nijmegen
  • Dr. Geerten W. Vuister University of Nijmegen


Language: English


Prerequisite knowledge: 

The course is intended for Ph.D. students and advanced undergraduate students who already have a thorough knowledge of NMR spectroscopy. Experience with NMR structure determination methods is strongly recommended.


Registration 

For registration contact

Ms. S. Tayler,
Bijvoet Center for Biomolecular Research
Padualaan 8, 3584 CH Utrecht
Phone: 030-2532652 Fax: 030-2537623
Email: secr@nmr.chem.uu.nl


Applicants will receive an acceptance notice as soon as possible.

Course topics

  • Prof. Dr. R. Boelens: NOEs and data processing
  • Dr. A.M.J.J. Bonvin: Molecular dynamics, force fields
  • Dr. M. Blackledge: Dipolar couplings and orientational restraints
  • Dr. H.A. Heus: Nucleic Acids
  • Dr. M. Nilges: ARIA, automated NOE assignment and structure calculations; structure prediction
  • Dr. C.A.E.M. Spronk: Structure validation
  • Dr. M. Tessari: Relaxation and dynamics
  • Dr. G.W. Vuister: J-coupling and chemical shifts