Understanding & Targeting

The basic science of the Hubrecht Institute, Utrecht University-Science and Veterinary Faculty, UMC Utrecht (Center for Molecular Medicine) and Princess Máxima Center, supported by excellent high-end equipment including high throughput screening, single cell (epi)genomics, microscopy and bioinformatics, serves to increase our knowledge of how cancer arises. Together with expertise from pharmaceutical sciences, it contributes to the development of novel molecular targeted therapies and nanotechnology.

Complementary expertise and research facilities in the areas of molecular, (stem)cell, and tissue biology, biochemistry, glycobiology, immunology, bioinformatics and nanotechnology are key to understand how the (pre)cancer cell develops and behaves. 


Single cell sequencing approaches have been instrumental in revealing the extent and level of tumor heterogeneity and cancer clonal evolution as well as in exposing the diversity in immune cell composition of the tumor (micro)environment. Systemic anti-cancer therapies have evolved from one-size fits all chemotherapeutic regimens to cancer cell targeted agents that profit from the increasing knowledge on the specific drivers of solid cancer and blood-based malignancies.  

Next generation experts

Our responsibility includes educating and training the next generation of researchers to create a dynamic environment in which innovative science will continue contributing to an ever-improving outcome for our patients.

PhD programmes

Within the Graduate School of Life Sciences offer the following PhD programmes tailored to this goal.

Students can also visit our other PhD programmes or Master's programmes.