NPC Proteins at Work Proteomics

Large scale analysis of proteins and their interactions in relation to biological functions

The Proteins At Work facilities of the Netherlands Proteomics Center (NPC) provides access to state-of-the-art proteomics technology, equipment and expertise to researchers in the Life Sciences from academia and industry. The core facility at Utrecht University is an expert center for state-of-the-art proteomics analysis that develops and implements innovative mass spectrometric methods for efficient and detailed characterization of biomolecules in relation to their biological function. The facility offers mass spectrometry based proteomics technology for applications ranging from single protein identifications to the analysis of complex, whole-cell lysate, samples and determination of post - translational modifications.

Equipment and access

The instrumentation of the facility consists of a wide range of HPLC-coupled high-end mass spectrometers, including state-of-the-art technologies such as high-resolution Orbitrap mass spectrometers with CID, HCD and ETD fragmentation capability. For data storage and analysis, the facility has dedicated computational clusters. The facility offers its services through research collaborations with scientists in the Netherlands, Europe and worldwide.

NPC Out-station

The proteomics facility at the UMC Utrecht is an outstation of the Proteins at Work initiative of NPC. The location of the facility within the Department Molecular Cancer Research, part of the Center for Molecular Medicine, ensures a strong background in biochemistry and molecular biology. Together with the high-end equipment, this allows for tailor made innovative approaches to aid fundamental, translational and clinical research into proteins and their modifications relevant for health and disease. Questions that are addressed range from single protein identification to proteome quantification. 
The facility offers its services primarily to researchers from the UMC Utrecht and its partners.


Proteins At Work Project Office
Utrecht University
Padualaan 8 (Room O611)
3584 CH Utrecht

Phone: +31 30 253 4564 

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