Biology Imaging Center

Visualising cells, subcellular structures, biological molecules and their interactions


The Biology Imaging Center (BIC) of Utrecht University provides access, support and training in advanced light and fluorescent microscopy techniques. The experts at the Center have unique expertise in fast multicolour imaging of intracellular dynamics in different types of mammalian cells, including neurons and cancer cells cultured in 2D and 3D. The combination of single molecule biophysics and strong cellular expertise, which makes it possible to perform analysis of the same molecules in vitro and in vivo, is unique. The center also has excellent expertise in laser microsurgery of cells in application to mammalian cell biology and neurobiology research.


The Biology Imaging Center incorporates equipment and expertise on Phase Contrast microscopy, VE-DIC microscopy, regular Wide-Field Epifluorescence microscopy, Total Internal Reflection Fluorescence (TIRF) microscopy and Laser Scanning and Spinning Disk Confocal microscopy. The advanced techniques in which the Center currently specializes include multicolor live cell imaging with a high spatial and temporal resolution, 3D live imaging of thick samples using Spinning Disk and Two-Photon microscopy, Fluorescence Recovery after Photobleaching (FRAP), photoactivation, photoablation, super-resolution localisation microscopy (PALM/STORM) and Stimulated Emission Depletion (STED) microscopy.


Ilya Grigoriev
Biology Imaging Center
Division of Cell Biology 
Department of Biology / Faculty of Science
Padualaan 8
3584 CH Utrecht

Phone: +31 30 253 3297