What are organoids


Organoids are cultures of human or animal tissue that have been established using protocols that allow long-term expansion of the tissue while maintaining the genetic and phenotypic stability, and the functional cellular diversity of the tissue over time. Culture-induced artefacts such as ‘crisis’ and genomic rearrangements, which are commonly observed when using standard culturing protocols, are prevented when using organoid culturing protocols. Organoid protocols have been established for many different tissues and tumour types and can be widely applied in areas such as cancer biology, toxicity screening, regenerative medicine, host-microbiome interactions, etc.