Research on patent ductus arteriosus
A patent ductus arteriosus (PDA) is a congenital anomaly in which a blood vessel that is essential before birth remains open after birth. Normally, this embryonic vessel—the ductus arteriosus—closes immediately after birth. If it does not, too much blood flows to the lungs, leading to strain on the heart. Without treatment, more than 60% of affected dogs die within the first year of life.
These dog breeds have an increased risk of patent ductus arteriosus:
The Frisian Stabyhoun
The Schapendoes
What are we researching?
When the ductus arteriosus does not close after birth, there is excessive volume strain on the left side of the heart, resulting in enlargement and a risk of left heart failure. Dogs may experience shortness of breath, fatigue, or fluid accumulation in the lungs.
With early screening, including a heart examination with ultrasound, a PDA can be diagnosed and treated in a timely manner. In addition, we conduct genetic research to better understand the hereditary background of this condition.
How do we do that?
A heart murmur heard during physical examination may be the first sign of a PDA. If one is detected, we recommend a heart ultrasound. This can be performed by one of our experienced cardiologists. In that case, we have some fur from the chest to get a clear image. With owner consent, a small amount of blood may also be taken during the screening for DNA storage. We use this material for genetic research into patent ductus arteriosus.