Research on hypertrophic cardiomyopathy
Hypertrophic cardiomyopathy (HCM) is the most common heart disease in cats. The condition is characterized by thickening of the heart muscle, especially in the wall of the left ventricle. This makes it harder for the heart to relax and fill with blood. This leads to shortness of breath, fluid accumulation, and sometimes cardiac arrhythmias or blood clots (thrombosis). In severe cases, HCM can lead to sudden death.
These cat breeds are at increased risk of hypertrophic cardiomyopathy:
The British Shorthair
The Maine Coon
The Ragdoll
The Sphynx
What are we researching?
Approximately 15% of all cats develop HCM. Within some breeds, this percentage is even higher. The disease is thought to be hereditary, possibly via a dominant genetic predisposition – just like in humans. However, it is not yet clear why some cats develop symptoms and others do not. Through screening and genetic research, we hope to gain a better understanding of the disease and ultimately be able to detect it earlier.
How do we do that?
A heart murmur or arrhythmia may be detected during a physical examination, but a definitive diagnosis of HCM requires an echocardiogram. This is performed by our experienced cardiologists. Owners of participating animals receive a detailed echocardiogram report.
During the screening, blood may also be taken for DNA storage, with owner consent. This DNA is used for genetic research into the hereditary causes of HCM.