Publications

Arunkumar, G.A., D. Bhavsar, T. Li, S. Strohmeier, V. Chromikova, F. Amanat, M. Bunyatov, P.C. Wilson, A.H. Ellebedy, G.J. Boons, V. Simon, R.P. de Vries, and F. Krammer. 2021. Functionality of the putative surface glycoproteins of the Wuhan spiny eel influenza virus. Nat. Commun. 12(1): 6161 (DOI: 10.1038/s41467-021-26409-2).

Asadpoor, M., Ithakisiou, G., Henricks, P.A.J., Pieters, R.J., Folkerts, G., Braber, S. 2021. Non-Digestible Oligosaccharides and Short Chain Fatty Acids as Therapeutic Targets against Enterotoxin-Producing Bacteria and Their Toxins. Toxins. 13: 175

Asadpoor, M., Ithakisiou, G.N., van Putten, J., Pieters, R.J., Folkerts, G., Braber, S. 2021. Antimicrobial Activities of Alginate and Chitosan Oligosaccharides Against Staphylococcus aureus and Group B Streptococcus. Front. Microbiol. 12: 700605

Asadpoor, M., Varasteh, S., Pieters, R.J., Folkerts, G., Braber, S. 2021. Differential Effects of Oligosaccharides on the Effectiveness of Ampicillin against Escherichia Coli in Vitro. PharmaNutrition. 16: 100264

Balsollier, C., Pieters, R.J., Anderluh, M. 2021. Overview of the Assays to Probe O-Linked β-N-Acetylglucosamine Transferase Binding and Activity. Molecules. 26: 1037.

Bosman, G.P., Oliveira, S., Simons, P.J., Sastre Torano, J., Somsen, G.W., Knippels, L., Haselberg, R., Pieters, R.J., Garssen, J., Knipping, K. 2021. Limited Lactosylation of Beta-Lactoglobulin from Cow's Milk Exerts Strong Influence on Antigenicity and Degranulation of Mast Cells. Nutrients. 13: 2041

Bravi F., Di Maso M., Eussen S.R.B.M., Agostoni C., Salvatori G., Profeti C., Tonetto P., Quitadamo P. A., Kazmierska I., Vacca E., Decarli A., Stahl B., Bertino E., Moro G.E., Ferraroni M. 2021. Dietary Patterns of Breastfeeding Mothers and Human Milk Composition: Data from the Italian MEDIDIET Study. On Behalf Of The Medidiet Working Group. Nutrients. 13(5): 1722 (DOI: 10.3390/nu13051722).

Bouwman, K.M., I. Tomris, H.L. Turner, R. van der Woude, T.M Shamorkina, G.P. Bosman, S. Herfst, B. Rockx, J. Snijder, B.L. Haagmans, A.B. Ward, G.J. Boons, and R.P. de Vries. 2021. Multimerization- and glycosylation-dependent receptor binding of SARS-CoV-2 spike proteins. PLoS Pathog. 17(2): e1009282 (DOI:10.1371/journal.ppat.1009282).

Chia L.W., Mank M., Blijenberg B., Bongers R.S., van Limpt K., Wopereis H., Tims S., Stahl B., Belzer C., Knol J. 2021. Cross-feeding between Bifidobacterium infantis and Anaerostipes caccae on lactose and human milk oligosaccharides. Benef Microbes. 12(1): 69-83 (DOI: 10.3920/BM2020.0005).

Chopra, P., A. Joshi, J. Wu,W. Lu,T. Yadavalli, M.A. Wolfert,D. Shukla,J. Zaia, and G.J. Boons. 2021. 3-O-Sulfation of heparan sulfate modulates protein binding and lyase degradation. Proc. Natl. Acad. Sci. U. S. A. 118(3): e2012935118 (DOI: 10.1073/pnas.2012935118).

Dai, M., W. Du, C. Martínez-Romero, T. Leenders, T. Wennekes, G. F. Rimmelzwaan, F. J. M. van Kuppeveld, R. A. M. Fouchier, A. Garcia-Sastre, E. de Vries, C. A. M. de Haan. 2021. Analysis of the Evolution of Pandemic Influenza A (H1N1) Virus Neuraminidase Reveals Entanglement of Different Phenotypic Characteristics. Mbio. 12(3), e00287-21 2 (DOI: 10.1128/mBio.00287-21).

Di Maso M., Eussen S.R.B.M., Bravi F., Moro G.E., Agostoni C., Tonetto P., Quitadamo P.A., Salvatori G., Profeti C., Kazmierska I., Vacca E., Decarli A., Stahl B., Bertino E., Ferraroni M.J. 2021. Dietary Intake of Breastfeeding Mothers in Developed Countries: A Systematic Review and Results of the MEDIDIET Study. Nutr. 151(11): 3459-3482 (DOI: 10.1093/jn/nxab258).

Dingess K.A., van Dam P., Zhu J., Mank M., Knipping K., Heck A.J.R., Stahl B. 2021. Optimization of a human milk-directed quantitative sIgA ELISA method substantiated by mass spectrometry. Anal. Bioanal. Chem. 413(20): 5037-5049 (DOI: 10.1007/s00216-021-03468-4).

Dingess K.A., Gazi I., van den Toorn H.W.P., Mank M., Stahl B., Reiding K.R., Heck A.J.R. 2021. Monitoring Human Milk beta-Casein Phosphorylation and O-Glycosylation Over Lactation Reveals Distinct Differences between the Proteome and Endogenous Peptidome. Int J Mol Sci. 22(15): 8140 (DOI: 10.3390/ijms22158140).

Eussen S.R.B.M., Mank M., Kottler R., Hoffmann X.K., Behne A., Rapp E., Stahl B., Mearin M.L., Koletzko B. 2021. Presence and Levels of Galactosyllactoses and Other Oligosaccharides in Human Milk and Their Variation during Lactation and According to Maternal Phenotype. Nutrients. 13(7): 2324 (DOI: 10.3390/nu13072324).

Gaide, N., M.N. Lucas, M. Delpont, G. Croville, K.M. Bouwman, A. Papanikolaou, R. van der Woude, I. Gagarinov, G.J. Boons, R.P. de Vries, R. Volmer, A. Teillaud, T. Vergne, C. Bleuart, G, Le Loc'h, M, Delverdier, and J.L. Guérin. 2021. Pathobiology of highly pathogenic H5 avian influenza viruses in naturally infected Galliformes and Anseriformes in France during winter 2015-2016. Vet. Res. Accepted for publication.

Haksar, D., Asadpoor, M., Heise, T., Shi, J., Braber, S., Folkerts, G., Ballell, L., Rodrigues, J., Pieters, R. J. 2021. Fighting Shigella by Blocking Its Disease-Causing Toxin. J. Med. Chem. 64: 6059-6069

Heesterbeek, D. A. C., R. M. Muts,V. P. van Hensbergen,P. de Saint Aulaire,T. Wennekes,B. W. Bardoel,N. M. van Sorge, S. H. M. Rooijakkers. 2021. Outer membrane permeabilization by the membrane attack complex sensitizes Gram-negative bacteria to antimicrobial proteins in serum and phagocytes. PLoS pathogens. 17(1), e1009227 8 (DOI: 10.1371/journal.ppat.1009227).

Heesters B.A., van Megesen K., Tomris I., de Vries R.P., Magri G., Spits H. 2021. Characterization of human FDCs reveals regulation of T cells and antigen presentation to B cells. J Exp Med. 218(10) (DOI: 10.1084/jem.20210790).

Hu R., Eussen S.R.B.M., Sijtsma F.P.C., Papi B., Stahl B., Jin Y., Mank M., Li J., Wang Z. 2021. Maternal dietary patterns are associated with human milk composition in Chinese lactating women. Nutrition. 91-92: 111392 (DOI: 10.1016/j.nut.2021.111392).

Huang, J., P. Chopra, L. Liu, T. Nagy, J. Murray, R.A. Tripp, G.J. Boons, and J.J. Mousa. 2021. Structure, immunogenicity, and conformation-dependent receptor binding of the postfusion human metapneumovirus F protein. J. Virol. 95(18): e00593-21 (DOI: 10.1128/JVI.00593-21).

Jong H., M.M.S.M. Wösten, T. Wennekes. 2021. Sweet impersonators: Molecular mimicry of host glycans by bacteria. Glycobiology (DOI 10.1093/glycob/cwab104).

Karlsson, R., P. Chopra, A. Joshi, Z. Yang, S.Y. Vakhrushev, T. Mandel Clausen, C.D. Painter, G.P. Szekeres, Y.-H. Chen, D.R. Sandoval, L. Hansen, J.D. Esko, K. Pagel, D.P. Dyer, J.E. Turnbull, H. Clausen*, G.J. Boons*, and R.L. Miller*. 2021. Dissecting structure-function of 3-O-sulfated heparin and engineered heparan sulfates. Sci. Adv. Sci. Adv. 7(52): eabl6026 (DOI: 10.1126/sciadv.abl6026).

Kontopodi E., Arslanoglu S., Bernatowicz-Lojko U., Bertino E., Bettinelli M.E., Buffin R., Cassidy T., van Elburg R.M., Gebauer C., Grovslien A., Hettinga K., Ioannou I., Klotz D., Mileusnić-Milenović R., Moro G.E., Picaud J.C., Stahl B., Weaver G., van Goudoever J.B., Wesolowska A. 2021. "Donor milk banking: Improving the future". A survey on the operation of the European donor human milk banks. PLoS One. 16(8):e0256435 (DOI: 10.1371/journal.pone.0256435).

Kontopodi E., Hettinga K., Stahl B., van Goudoever J.B., M van Elburg R. 2021. Testing the effects of processing on donor human Milk: Analytical methods. Food Chem. 373(Pt. A):131413 (DOI: 10.1016/j.foodchem.2021.131413).

Li, Z., Y. Lang, L. Liu, M.I. Bunyatov, A. Isaza Sarmiento, R.J. de Groot, and G.J. Boons. 2021. Synthetic O-acetylated sialosides facilitate functional receptor identification for human respiratory viruses. Nat. Chem. 13(5): 496-503 (DOI: 10.1038/s41557-021-00655-9).

Li, Z., L. Unione, L. Liu, Y. Lang, R.P. de Vries, R.J. de Groot, and G.J. Boons. 2021. Synthetic O-acetylated sialosides and their acetamido-deoxy analogs as probes for coronaviral hemagglutinin-esterase recognition. J. Am. Chem. Soc. In press (DOI: 10.1021/jacs.1c10329).

Liu, L., P. Chopra, X. Li, K.M. Bouwman, S.M Tompkins,M.A. Wolfert, R.P. de Vries, and G.J. Boons. 2021. Heparan sulfate proteoglycans as attachment factor for SARS-CoV-2. ACS Cent. Sci. 7(6): 1009-1018 (DOI: 10.1021/acscentsci.1c00010).

Luijkx, Y.M.C.A., S. Jongkees, K. Strijbis, T. Wennekes. 2021. Development of a 1, 2-difluorofucoside activity-based probe for profiling GH29 fucosidases. Organic & Biomolecular Chemistry. 19(13):2968-2977 (DOI: 10.1039/D1OB00054C).

Martínez-Alarcón, D., Balloy, V., Bouchara, J. P., Pieters, R. J., Varrot, A. 2021. Biochemical and structural studies of target lectin SapL1 from the emerging opportunistic microfungus Scedosporium apiospermum. Sci. Rep. 11: 16109

Meng, X., M.M.S.M. Wösten, G.J. Boons, and T. Wennekes. 2021. Metabolic labeling of legionaminic acid in flagellin glycosylation of Campylobacter jejuni identifies Maf4 as a putative legionaminyl transferase. Angew. Chem. Int. Ed. 60(47): 24811-24816 (DOI: 10.1002/anie.202107181).

Montez de Sousa Í.R., Wang Z., Hu R., Stahl B., Jin Y., Eussen S.R.B.M., Li J. 2021. Dietary Intake of Chinese Lactating Women Is Associated with the Fatty Acid Profile of Their Milk. Ann. Nutr. Metab. Dec 2: 1-13 (DOI: 10.1159/000520515).

Moure, M.J., A. Gimeno, S. Delgado, T. Diercks, G.J. Boons, J. Jimenez-Barbero, and A. Arda. 2021. Selective 13C-labels on repeating glycan oligomers to reveal protein binding epitopes through NMR: polylactosamine binding to galectins. Angew. Chem. Int. Ed. 60(34): 18777-18782 (DOI: 10.1002/anie.202106056).

Nemanichvili N., Berends A.J., Tomris I., Barnard K.N., Parrish C.R., Grone A., Rijks J.M., Verheije M.H., de Vries R.P. 2021. Influenza D binding properties vary amongst the two major virus clades and wildlife species. Vet Microbiol. 264: 109298 (DOI: 10.1016/j.vetmic.2021.10929).

Nemanichvili N., Berends A.J., Wubbolts R.W., Grone A., Rijks J.M., de Vries R.P., Verheije M.H. 2021. Tissue Microarrays to visualize influenza D attachment to host receptors in the respiratory tract of farm animals. Viruses. 13(4) (DOI: 10.3390/v13040586).

Nguyen, L., K.A. McCord, D.T. Bui, K.M. Bouwman, E.N. Kitova, M. Elaish, D. Kumawat, G.C. Daskhan, I. Tomris, L. Han, P. Chopra, T.-J. Yang, S.D. Willows, A.L. Mason, L.K. Mahal, T.L. Lowary, L.J. West, S.D. Hsu, T. Hobman, S.M. Tompkins, G.J. Boons, R.P. de Vries, M.S. Macauley, and J.S. Klassen. 2022. Sialic acid-dependent binding and viral entry of SARS-CoV-2. Nat. Chem. Biol. 18(1): 81-90 (DOI: 10.1038/s41589-021-00924-1).

Sadelhoff van J.H.J., Siziba L.P., Buchenauer L., Mank M., Wiertsema S.P., Hogenkamp A., Stahl B., Garssen J., Rothenbacher D., Genuneit J. 2021. Free and Total Amino Acids in Human Milk in Relation to Maternal and Infant Characteristics and Infant Health Outcomes: The Ulm SPATZ Health Study. Nutrients. 13(6):2009 (DOI: 10.3390/nu13062009).

Sastre Toraño, J., O. Aizpurua-Olaizola, N. Wei, T. Li, L. Unione, G. Jiménez-Osés, F. Corzana, V.J. Somovilla, J.M. Falcon-Perez, and G.J. Boons. 2021. Identification of isomeric N-glycans by conformer distribution fingerprinting using ion mobility-mass spectrometry. Chem. Eur. J. 26(6): 2149-2154 (DOI: 10.1002/chem.202004522).

Schuurmans, C.C.L., A.J. Brouwer, J.A.W. Jong, G.J.P.H. Boons, W.E. Hennink, and T. Vermonden. 2021. Hydrolytic (in)stability of methacrylate esters in covalently cross-linked hydrogels based on chondroitin sulfate and hyaluronic acid methacrylate. ACS Omega 6(40): 26302-26310 (DOI: 10.1021/acsomega.1c03395).

Sewgobind, N.V., Albers, S., Pieters, R.J. 2021. Functions and Inhibition of Galectin-7, an Emerging Target in Cellular Pathophysiology. Biomolecules. 11:1720

Shi, J., Sharif,  S., Balsollier, C., Ruijtenbeek, R., Pieters, R. J., Jongkees, S. A. K. 2021. C‐terminal tag location hampers in vitro profiling of OGT peptide substrates by mRNA display. ChemBioChem. 22:666-671

Siziba L.P., Lorenz L., Brenner H., Carr P., Stahl B., Mank M., Marosvölgyi T., Decsi T., Szabó É., Rothenbacher D., Genuneit J. 2021. Changes in human milk fatty acid composition and maternal lifestyle-related factors over a decade: a comparison between the two Ulm Birth Cohort Studies. Br J Nutr. 126(2): 228-235 (DOI: 10.1017/S0007114520004006).

Siziba L.P., Mank M., Stahl B., Kurz D., Gonsalves J., Blijenberg B., Rothenbacher D., Genuneit J. 2021. Associations of Human Milk Oligosaccharides With Otitis Media and Lower and Upper Respiratory Tract Infections up to 2 Years: The Ulm SPATZ Health Study. Front Nutr. 8: 761129 (DOI: 10.3389/fnut.2021.761129).

Siziba L.P, Mank M., Stahl B., Gonsalves J., Blijenberg B., Rothenbacher D., Genuneit J. 2021. Human Milk Oligosaccharide Profiles over 12 Months of Lactation: The Ulm SPATZ Health Study. Nutrients. 13(6): 1973 (DOI: 10.3390/nu13061973).

Spruit, C.M., N. Nemanichvili, M. Okamatsu, H. Takematsu, H., G.J. Boons, and R.P. de Vries. 2021. N-glycolylneuraminic acid in animal models for human influenza A virus. Viruses 15(5): 815 (DOI: 10.3390/v13050815).

Spruit, C.M., X. Zhu, I. Tomris, M. Rios Carrasco, A.X. Han, F. Broszeit, R. van der Woude, K.M. Bouwman, M.M.T. Luu, K. Matsuno, Y. Sakoda, C.A. Russell, I.A. Wilson, G.J. Boons, and R.P. de Vries. 2021. N-glycolylneuraminic acid binding of avian and equine H7 influenza A viruses. J. Vir. Accepted for publication.

Srivastava, A.D., L. Unione, M. Bunyatov, I.A. Gagarinov, S. Delgado, N.G.A. Abrescia, A. Ardá, and G.J. Boons. 2021. Chemoenzymatic synthesis of complex N-glycans of the parasite S. mansoni to examine the importance of epitope presentation on DC-SIGN recognition. Angew. Chem. Int. Ed. 60(35): 19287-19296 (DOI: 10.1002/anie.202105647).

Su, X., Ramírez-Escudero, M., Sun, F., van den Dikkenberg, J.B., van Steenbergen, M.J., Pieters, R.J., Janssen, B.J.C., van Hasselt, P.M., Hennink, W.E., van Nostrum, C.F. 2021. Internalization and Transport of PEGylated Lipid-Based Mixed Micelles across Caco-2 Cells Mediated by Scavenger Receptor B1. Pharmaceutics. 13: 2022

Tas R.P., V. Sampaio‐Pinto, T. Wennekes, L.W. van Laake, I.K. Voets. 2021. From the freezer to the clinic: Antifreeze proteins in the preservation of cells, tissues, and organs. EMBO reports. 22(3), e52162 2 (DOI: 10.15252/embr.202052162).

Toutounchi N.S., Braber S., Hogenkamp A., Varasteh S., Cai Y., Wehkamp T., Tims S., Leusink-Muis T., van Ark I., Wiertsema S., Stahl B., Kraneveld A.D., Garssen J., Folkerts G., Van't Land B. 2021. Human Milk Oligosaccharide 3'-GL Improves Influenza-Specific Vaccination Responsiveness and Immunity after Deoxynivalenol Exposure in Preclinical Models. Nutrients. 13(9): 3190 (DOI: 10.3390/nu13093190).

Verheyen S, J. Blatterer J, M.R. Speicher, G.S. Bhavani, G.J. Boons, M.B. Ilse, D. Andrae, J. Sproß, F.M. Vaz, S.G. Kircher, L. Posch-Pertl, D. Baumgartner, T. Lübke, H. Shah, A. Al Kaissi, K.M. Girisha, and B. Plecko. 2021. Novel subtype of mucopolysaccharidosis caused by arylsulfatase K (ARSK) deficiency. J. Med. Gen. In press (DOI: 10.1136/jmedgenet-2021-108061).

Wei, X., Pieters, R. J. 2021. Multivalency Effects in Neuraminidase Inhibitor Design for Influenza Virus. Arkivoc. 4:297-312

Weiss, M., Loi, E. M., Sterle, M., Balsollier, C., Tomašič, T., Pieters, R. J., Gobec, M., Anderluh, M. 2021. New Quinolinone O-GlcNAc Transferase Inhibitors Based on Fragment Growth. Front. Chem. 9:666122

Wu, J., P. Chopra, G.J. Boons, and J. Zaia.^. 2021. Influence of saccharide modifications on heparin lyase III substrate specificities. Glycobiology. In press (DOI: 10.1093/ glycob/cwab023).

Zaree P., Sastre Torano, J., de Haan, C. A. M., Scheltema, R. A., Barendregt, A., Thijssen, V., Yu, G., Flesch, F., Pieters, R. J. 2021. The assessment of Pseudomonas aeruginosa lectin LecA binding characteristics of divalent galactosides using multiple techniques. Glycobiology. 31:1490-1499

Zhu J., Dingess K.A., Mank M., Stahl B., Heck A.J.R. 2021. Personalized Profiling Reveals Donor- and Lactation-Specific Trends in the Human Milk Proteome and Peptidome. J. Nutr. 151(4):826-839 (DOI: 10.1093/jn/nxaa445).

Chopra, P., A. Joshi, J. Wu, W. Lu, T. Yadavalli, M.A. Wolfert, D. Shukla, J. Zaia, G.J. Boons. 2020. 2020. 3-O-Sulfation of heparan sulfate modulates protein binding and lyase degradation. Proc. Natl. Acad. Sci. U. S. A. Accepted for publication

Liu, M., V. Thijssen, S.A.K. Jongkees. 2020. Suppression of formylation provides an alternative approach to vacant codon creation in bacterial in vitro translation. Angew. Chem. Int. Ed.: In press (DOI: 10.1002/anie.202003779).  [PMID: 32840944]

Li, T., M.A. Wolfert, N. Wei, R. Huizinga, B.C. Jacobs, G.J. Boons. 2020. Chemoenzymatic synthesis of Campylobacter jejuni lipo-oligosaccharide core domains to examine Guillain-Barré syndrome serum antibody specificities. J. Am. Chem. Soc. 142(46): 19611-19621.  [PMID: 33164488]

Horn, V., S.A.K. Jongkees, H. van Ingen. 2020. Mimicking the nucleosomal context in peptide-based binders of a H3K36me reader increases binding affinity while altering the binding mode. Molecules 25(21): 4951.  [PMID: 33114657]

Williams, C.R., L. Chen, E.S. Sheppard, P. Chopra, J. Locklin, G.J. Boons, D.C. Krause. 2020. Distinct Mycoplasma pneumoniae interactions with sulfated and sialylated receptors. Infect. Immun. 88(11): e00392-00320.  [PMID: 32839185]

Sun, L., P. Chopra, G.J. Boons. 2020. Modular synthesis of heparan sulfate oligosaccharides having N-acetyl and N-sulfate moieties. J. Org. Chem. In press (DOI: 10.1021/acs.joc.0c01881).

Sastre Toraño, J., O. Aizpurua-Olaizola, N. Wei, T. Li, L. Unione, G. Jiménez-Osés, F. Corzana, V.J. Somovilla, J.M. Falcon-Perez, G.J. Boons. 2020. Identification of isomeric N-glycans by conformer distribution fingerprinting using ion mobility-mass spectrometry. Chem. Eur. J. In press (DOI: 10.1002/chem.202004522).  [PMID: 33047840]

Lang, Y., W. Li, Z. Li, D. Koerhuis, A.C.S. van den Burg, E. Rozemuller, B.J. Bosch, F.J.M. van Kuppeveld, G.J. Boons, E.G. Huizinga, H.M. van der Schaar, R.J. de Groot. 2020. Coronavirus hemagglutinin-esterase and spike proteins coevolve for functional balance and optimal virion avidity. Proc. Natl. Acad. Sci. U. S. A. 117(41): 25759-25770.  [PMID: 32994342]

Shi, J., S. Sharif, C. Balsollier, R. Ruijtenbeek, R.J. Pieters, S.A.K. Jongkees. 2020. C-terminal tag location hampers in vitro profiling of OGT peptide substrates by mRNA display. ChemBioChem In press (DOI: 10.1002/cbic.202000624).  [PMID: 33022805]

Verpalen, E.C.J.M., A.J. Brouwer, G.J. Boons. 2020. Synthesis of monophosphoryl lipid A using 2-naphtylmethyl ethers as permanent protecting groups. Carbohydr. Res. 498 In press (DOI: 10.1016/j.carres.2020.108152).

Boruah, B.M., R. Kadirvelraj, L. Liu, A. Ramiah, C. Li, G. Zong, G.P. Bosman, J.Y. Yang, L.X. Wang, G.J. Boons, Z.A. Wood, K.W. Moremen. 2020. Characterizing human alpha-1,6-fucosyltransferase (FUT8) substrate specificity and structural similarities with related fucosyltransferases. J. Biol. Chem. In press (DOI: 10.1074/jbc.RA1120.014625).  [PMID: 33004438]

Steigenberger, B., H.W.P. van den Toorn, E. Bijl, J.F. Greisch, O. Rather, M. Lubeck, R.J. Pieters, A.J.R. Heck, R.A. Scheltema. 2020. Benefits of collisional cross section assisted precursor selection (caps-PASEF) for cross-linking mass spectrometry. Mol. Cell. Proteomics 19(10): 1677-1687.  [PMID: 32694122]

Gungor, E., P. Brouwer, L.W. Dijkhuizen, D.C. Shaffar, K.G.J. Nierop, R.C.H. de Vos, J. Sastre Torano, I.M. van der Meer, H. Schluepmann. 2020. Azolla ferns testify: seed plants and ferns share a common ancestor for leucoanthocyanidin reductase enzymes. New Phytol. In press (DOI: 10.1111/nph.16896).  [PMID: 32858769]

van Haren, M.J., Y. Zhang, N. Buijs, V. Thijssen, D. Sartini, M. Emanuelli, S. Jongkees, N. Martin. 2020. Macrocyclic peptides as allosteric inhibitors of nicotinamide N-methyltransferase (NNMT). ChemRxiv Preprint (DOI: 10.26434/chemrxiv.12973130.v12973131).

Trabszo, C., B. Ramms, P. Chopra, R. Lullmann-Rauch, S. Stroobants, J. Spross, A. Jeschke, T. Schinke, G.J. Boons, J.D. Esko, T. Lubke, T. Dierks. 2020. Arylsulfatase K inactivation causes mucopolysaccharidosis due to deficient glucuronate desulfation of heparan and chondroitin sulfate. Biochem. J. 477(17): 3433-3451.  [PMID: 32856704]

Bouwman, K.M., I. Tomris, H.L. Turner, R. van der Woude, G.P. Bosman, B. Rockx, S. Herfst, B.L. Haagmans, A. Ward, B., G.J. Boons, R.P. de Vries. 2020. Multimerization- and glycosylation-dependent receptor binding of SARS CoV-2 spike proteins. bioRxiv Preprint (DOI: 0.1101/2020.1109.1104.282558).

Du, W., M.A. Wolfert, B. Peeters, F.J.M. van Kuppeveld, G.J. Boons, E. de Vries, C.A.M. de Haan. 2020. Mutation of the second sialic acid-binding site of influenza A virus neuraminidase drives compensatory mutations in hemagglutinin. PLoS Pathog. 16(8): e1008816.  [PMID: 32853241]

Luijkx, Y.M.C.A., N.M.C. Bleumink, J. Jiang, H.S. Overkleeft, M.M.S.M. Wosten, K. Strijbis, T. Wennekes. 2020. Bacteroides fragilis fucosidases facilitate growth and invasion of Campylobacter jejuni in the presence of mucins. Cell. Microbiol.: e13252.  [PMID: 32827216]

Lettow, M., M. Grabarics, K. Greis, E. Mucha, D.A. Thomas, P. Chopra, G.J. Boons, R. Karlsson, J.E. Turnbull, G. Meijer, R.L. Miller, G. von Helden, K. Pagel. 2020. Cryogenic infrared spectroscopy reveals structural modularity in the vibrational fingerprints of heparan sulfate diastereomers. Anal. Chem. 92(15): 10228-10232.  [PMID: 32658472]

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Jansen, A.J.G., T. Spaan, H.Z. Low, D. Di Iorio, J. van den Brand, M. Tieke, A. Barendrecht, K. Rohn, G. van Amerongen, K. Stittelaar, W. Baumgartner, A. Osterhaus, T. Kuiken, G.J. Boons, J. Huskens, M. Boes, C. Maas, E. van der Vries. 2020. Influenza-induced thrombocytopenia is dependent on the subtype and sialoglycan receptor and increases with virus pathogenicity. Blood Adv. 4(13): 2967-2978.  [PMID: 32609845]

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Asadpoor, M., C. Peeters, P.A.J. Henricks, S. Varasteh, R.J. Pieters, G. Folkerts, S. Braber. 2020. Anti-pathogenic functions of non-digestible oligosaccharides in vitro. Nutrients 12(6): 1789.  [PMID: 32560186]

Johansen-Leete, J., T. Passioura, S.R. Foster, R.P. Bhusal, D.J. Ford, M. Liu, S.A.K. Jongkees, H. Suga, M.J. Stone, R.J. Payne. 2020. Discovery of potent cyclic sulfopeptide chemokine inhibitors via reprogrammed genetic code mRNA display. J. Am. Chem. Soc. 142(20): 9141-9146.  [PMID: 32330017]

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Figueroa, T., P. Bessière, A. Coggon, K.M. Bouwman, R. van der Woude, M. Delverdier, M.H. Verheije, R.P. de Vries, R. Volmer. 2020. The microbiota contributes to the control of highly pathogenic H5N9 influenza virus replication in ducks. J. Virol. 94(10).  [PMID: 32102887]

Talsma, D.T., F. Poppelaars, W. Dam, A.H. Meter-Arkema, R.R. Vives, P. Gal, G.J. Boons, P. Chopra, A. Naggi, M.A. Seelen, S.P. Berger, M.R. Daha, C.A. Stegeman, J. van den Born, C. Consortium. 2020. MASP-2 is a heparin-binding protease; Identification of blocking oligosaccharides. Front. Immunol. 11: 732.  [PMID: 32425936]

Dumas, E.K., H. Demiraslan, R.J. Ingram, R.M. Sparks, E. Muns, A. Zamora, J. Larabee, L. Garman, J.D. Ballard, G.J. Boons, J.A. James, U. Kayabas, M. Doganay, A.D. Farris. 2020. Toxin-neutralizing antibodies elicited by naturally acquired cutaneous anthrax are elevated following severe disease and appear to target conformational epitopes. PLoS ONE 15(4): e0230782.  [PMID: 32294093]

Liu, Y., L. Scrivano, J.D. Peterson, M. Fens, I.B. Hernandez, B. Mesquita, J. Sastre Toraño, W.E. Hennink, C.F. van Nostrum, S. Oliveira. 2020. EGFR-targeted nanobody functionalized polymeric micelles loaded with mTHPC for selective photodynamic therapy. Mol. Pharm. 17(4): 1276-1292.  [PMID: 32142290]

Kikutani, Y., M. Okamatsu, S. Nishihara, S. Takase-Yoden, T. Hiono, R.P. de Vries, R. McBride, K. Matsuno, H. Kida, Y. Sakoda. 2020. E190V substitution of H6 hemagglutinin is one of key factors for binding to sulfated sialylated glycan receptor and infection to chickens. Microbiol. Immunol. 64(4): 304-312.  [PMID: 31943329]

Miller, R.L., S.E. Guimond, R. Schworer, O.V. Zubkova, P.C. Tyler, Y. Xu, J. Liu, P. Chopra, G.J. Boons, M. Grabarics, C. Manz, J. Hofmann, N.G. Karlsson, J.E. Turnbull, W.B. Struwe, K. Pagel. 2020. Shotgun ion mobility mass spectrometry sequencing of heparan sulfate saccharides. Nat. Commun. 11(1): 1481.  [PMID: 32198425]

Parsons, L.M., Y. An, L. Qi, M. White, R. van der Woude, K. Hartshorn, J.K. Taubenberger, R.P. de Vries, J.F. Cipollo. 2020. Influenza viurs hemagglutinins H2, H5, H6, and H11 are not targets of pulmonary surfactant protein D: N-glycan subtypes in host-pathogen interactions. J. Virol. 94(5): In press.  [PMID: 31826991]

Haksar, D., L. Quarles van Ufford, R.J. Pieters. 2020. A hybrid polymer to target blood group dependence of cholera toxin. Org. Biomol. Chem. 18(1): 52-55.  [PMID: 31802094]

Bouwman, K.M., L.M. Parsons, A.J. Berends, R.P. de Vries, J.F. Cipollo, M.H. Verheije. 2020. Three amino acid changes in avian coronavirus spike protein allow binding to kidney tissue. J. Virol. 94(2).  [PMID: 31694947]

Singh, J., C. Her, N. Supekar, G.J. Boons, V.V. Krishnan, C.L. Brooks. 2020. Role of glycosylation on the ensemble of conformations in the MUC1 immunodominant epitope. J. Pept. Sc.: e3229.  [PMID: 31729101]

Sastre Toraño, J., I.A. Gagarinov, G.M. Vos, F. Broszeit, A.D. Srivastava, M. Palmer, J.I. Langridge, O. Aizpurua-Olaizola, V.J. Somovilla, G.J. Boons. 2019. Ion-mobility spectrometry can assign exact fucosyl positions in glycans and prevent misinterpretation of mass spectrometry data after gas-phase rearrangement. Angew. Chem. Int. Ed. 58(49): 17616-17620.  [PMID: 31544998]

Hoeksma, J., T. Misset, C. Wever, J. Kemmink, J. Kruijtzer, K. Versluis, R.M.J. Liskamp, G.J. Boons, A.J.R. Heck, T. Boekhout, J. den Hertog. 2019. A new perspective on fungal metabolites: identification of bioactive compounds from fungi using zebrafish embryogenesis as read-out. Sc. Rep. 9(1): 17546.  [PMID: 31772307]

Liu, H., A. Joshi, P. Chopra, L. Liu, G.J. Boons, J.S. Sharp. 2019. Salt-free fractionation of complex isomeric mixtures of glycosaminoglycan oligosaccharides compatible with ESI-MS and microarray analysis. Sc. Rep. 9(1): 16566.  [PMID: 31719635]

van der Made, T.K., M. Fedecostante, D. Scotcher, A. Rostami-Hodjegan, J. Sastre Toraño, I. Middel, A.S. Koster, K.G. Gerritsen, V. Jankowski, J. Jankowski, J.G.J. Hoenderop, R. Masereeuw, A. Galetin. 2019. Quantitative translation of microfluidic transporter in vitro data to in vivo reveals impaired albumin-facilitated indoxyl sulfate secretion in chronic kidney disease. Mol. Pharm. 16(11): 4551-4562.  [PMID: 31525064]

Steigenberger, B., H.B. Schiller, R.J. Pieters, R.A. Scheltema. 2019. Finding and using diagnostic ions in collision induced crosslinked peptide fragmentation spectra. Int. J. Mass Spectrom. 444: 116184.

Steigenberger, B., R.J. Pieters, A.J.R. Heck, R.A. Scheltema. 2019. PhoX: an IMAC-enrichable cross-linking reagent. ACS Cent. Sci. 5(9): 1514-1522.  [PMID: 31572778]

Chopra, P., M.T. Logun, E.M. White, W. Lu, J. Locklin, L. Karumbaiah, G.J. Boons. 2019. Fully synthetic heparan sulfate-based neural tissue construct that maintains the undifferentiated state of neural stem cells. ACS Chem. Biol. 14(9): 1921-1929.  [PMID: 31389687]

Gray, C.J., L.G. Migas, P.E. Barran, K. Pagel, P.H. Seeberger, C.E. Eyers, G.J. Boons, N.L.B. Pohl, I. Compagnon, G. Widmalm, S.L. Flitsch. 2019. Advancing solutions to the carbohydrate sequencing challenge. J. Am. Chem. Soc. 141(37): 14463-14479.  [PMID: 31403778]

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Chao, L., S. Jongkees. 2019. High-throughput approaches in carbohydrate-active enzymology: Glycosidase and glycosyl transferase inhibitors, evolution, and discovery. Angew. Chem. Int. Ed. 58(37): 12750-12760.  [PMID: 30913359]

Yu, G., A.C. Vicini, R.J. Pieters. 2019. Assembly of divalent ligands and their effect on divalent binding to Pseudomonas aeruginosa lectin LecA. J. Org. Chem. 84(5): 2470-2488.  [PMID: 30681333]

Zhang, H., H. Ippel, M.C. Miller, T.J. Wong, A.W. Griffioen, K.H. Mayo, R.J. Pieters. 2019. Hybrid ligands with calixarene and thiodigalactoside groups: galectin binding and cytotoxicity. Org. Chem. Front. 6(16): 2981-2990.

Goldbach, L., B.J.A. Vermeulen, S. Caner, M. Liu, C. Tysoe, L. van Gijzel, R. Yoshisada, M. Trellet, H. van Ingen, G.D. Brayer, A. Bonvin, S.A.K. Jongkees. 2019. Folding then binding vs folding through binding in macrocyclic peptide inhibitors of human pancreatic alpha-amylase. ACS Chem. Biol. 14(8): 1751-1759.  [PMID: 31241898]

t’ Hart, I.M.E., T. Li, M.A. Wolfert, S. Wang, K.W. Moremen, G.J. Boons. 2019. Chemoenzymatic synthesis of the oligosaccharide moiety of the tumor-associated antigen disialosyl globopentaosylceramide. Org. Biomol. Chem. 17(31): 7304-7308.  [PMID: 31339142]

Jansen, J., K. Jansen, E. Neven, R. Poesen, A. Othman, A. van Mil, J. Sluijter, J. Sastre Toraño, E.A. Zaal, C.R. Berkers, D. Esser, H.J. Wichers, K. van Ede, M. van Duursen, S. Burtey, M.C. Verhaar, B. Meijers, R. Masereeuw. 2019. Remote sensing and signaling in kidney proximal tubules stimulates gut microbiome-derived organic anion secretion. Proc. Natl. Acad. Sci. U. S. A. 116(32): 16105-16110.  [PMID: 31341083]

Gagarinov, I.A., T. Li, N. Wei, J. Sastre Toraño, R.P. de Vries, M.A. Wolfert, G.J. Boons. 2019. Protecting-group-controlled enzymatic glycosylation of oligo-N-acetyllactosamine derivatives. Angew. Chem. Int. Ed. 58(31): 10547-10552.  [PMID: 31108002]

Gao, Y., M.J. van Haren, E.E. Moret, J.J.M. Rood, D. Sartini, A. Salvucci, M. Emanuelli, P. Craveur, N. Babault, J. Jin, N.I. Martin. 2019. Bisubstrate inhibitors of nicotinamide N-methyltransferase (NNMT) with enhanced activity. J. Med. Chem. 62(14): 6597-6614.  [PMID: 31265285]

Mahon, C.S., G.C. Wildsmith, D. Haksar, E. de Poel, J.M. Beekman, R.J. Pieters, M.E. Webb, W.B. Turnbull. 2019. A 'catch-and-release' receptor for the cholera toxin. Faraday Discuss.: 112-127.  [PMID: 31313796]

Lu, W., W. Du, V.J. Somovilla, G. Yu, D. Haksar, E. de Vries, G.J. Boons, R.P. de Vries, C.A.M. de Haan, R.J. Pieters. 2019. Enhanced inhibition of influenza A virus adhesion by di- and trivalent hemagglutinin inhibitors. J. Med. Chem. 62(13): 6398-6404.  [PMID: 31251606]

De Groof, T.W.M., V. Mashayekhi, T.S. Fan, N.D. Bergkamp, J. Sastre Toraño, J.R. van Senten, R. Heukers, M.J. Smit, S. Oliveira. 2019. Nanobody-targeted photodynamic therapy selectively kills viral GPCR-expressing glioblastoma cells. Mol. Pharm. 16(7): 3145-3156.  [PMID: 31244224]

Sastre Toraño, J., R. Ramautar, G. de Jong. 2019. Advances in capillary electrophoresis for the life sciences. J. Chrom. B 1118-1119: 116-136.  [PMID: 31035134]

Broszeit, F., N. Tzarum, X. Zhu, N. Nemanichvili, D. Eggink, T. Leenders, Z. Li, L. Liu, M.A. Wolfert, A. Papanikolaou, C. Martinez-Romero, I.A. Gagarinov, W. Yu, A. Garcia-Sastre, T. Wennekes, M. Okamatsu, M.H. Verheije, I.A. Wilson, G.J. Boons, R.P. de Vries. 2019. N-Glycolylneuraminic acid as a receptor for influenza A viruses. Cell Rep. 27(11): 3284-3294 e3286.  [PMID: 31189111]

Du, W., H. Guo, V.S. Nijman, J. Doedt, E. van der Vries, J. van der Lee, Z. Li, G.J. Boons, F.J.M. van Kuppeveld, E. de Vries, M. Matrosovich, C.A.M. de Haan. 2019. The 2nd sialic acid-binding site of influenza A virus neuraminidase is an important determinant of the hemagglutinin-neuraminidase-receptor balance. PLoS Pathog. 15(6): e1007860.  [PMID: 31181126]

Tortorici, M.A., A.C. Walls, Y. Lang, C. Wang, Z. Li, D. Koerhuis, G.J. Boons, B.J. Bosch, F.A. Rey, R.J. de Groot, D. Veesler. 2019. Structural basis for human coronavirus attachment to sialic acid receptors. Nat. Struct. Mol. Biol. 26(6): 481-489.  [PMID: 31160783]

Parsons, L.M., K.M. Bouwman, H. Azurmendi, R.P. de Vries, J.F. Cipollo, M.H. Verheije. 2019. Glycosylation of the viral attachment protein of avian coronavirus is essential for host cell and receptor binding. J. Biol. Chem. 294(19): 7797-7809.  [PMID: 30902814]

Hu, Y., X. Cao, X. Li, Y. Wang, G.J. Boons, J. Deng, H. Jiang. 2019. The three-dimensional structure and recognition mechanism of Manduca sexta peptidoglycan recognition protein-1. Insect Biochem. Mol. Biol. 108: 44-52.  [PMID: 30905759]

Bouwman, K.M., M. Delpont, F. Broszeit, R. Berger, E.A.W.S. Weerts, M.N. Lucas, M. Delverdier, S. Belkasmi, A. Papanikolaou, G.J. Boons, J.L. Guerin, R.P. de Vries, M.F. Ducatez, M.H. Verheije. 2019. Guinea fowl coronavirus diversity has phenotypic consequences for glycan and tissue binding. J. Virol. 93(10): e00067-00019.  [PMID: 30842318]

van der Beek, S.L., A. Zorzoli, E. Canak, R.N. Chapman, K. Lucas, B.H. Meyer, D. Evangelopoulos, L.P.S. de Carvalho, G.J. Boons, H.C. Dorfmueller, N.M. van Sorge. 2019. Streptococcal dTDP-L-rhamnose biosynthesis enzymes: functional characterization and lead compound identification. Mol. Microbiol. 111(4): 951-964.  [PMID: 30600561]

Sharif, S., J. Shi, R. Ruijtenbeek, R.J. Pieters. 2019. Study of cross talk between phosphatases and OGA on a ZO-3-derived peptide. Amino Acids 51(4): 739-743.  [PMID: 30725225]

Lu, W., R.J. Pieters. 2019. Carbohydrate-protein interactions and multivalency: implications for the inhibition of influenza A virus infections. Expert Opin. Drug Discov. 14(4): 387-395.  [PMID: 30722704]

Aldosari, M.H., R.P. de Vries, L.R. Rodriguez, N.A. Hesen, N. Beztsinna, A.B.P. van Kuilenburg, C.E.M. Hollak, H. Schellekens, E. Mastrobattista. 2019. Liposome-targeted recombinant human acid sphingomyelinase: Production, formulation, and in vitro evaluation. Eur. J. Pharm. Biopharm. 137: 185-195.  [PMID: 30818011]

Haksar, D., E. de Poel, L.C. Quarles van Ufford, S. Bhatia, R. Haag, J. Beekman, R.J. Pieters. 2019. Strong inhibition of cholera toxin B subunit by affordable, polymer-based multivalent inhibitors. Bioconjug. Chem. 30(3): 785-792.  [PMID: 30629410]

Yu, G., D.M.E. Thies‐Weesie, R.J. Pieters. 2019. Tetravalent Pseudomonas aeruginosa adhesion lectin LecA inhibitor for enhanced biofilm inhibition. Helv. Chim. Acta 102(3): e1900014.

Li, T., L. Liu, N. Wei, J.Y. Yang, D.G. Chapla, K.W. Moremen, G.J. Boons. 2019. An automated platform for the enzyme-mediated assembly of complex oligosaccharides. Nat. Chem. 11(3): 229-236.  [PMID: 30792508]

Nemanichvili, N., I. Tomris, H.L. Turner, R. McBride, O.C. Grant, R. van der Woude, M.H. Aldosari, R.J. Pieters, R.J. Woods, J.C. Paulson, G.J. Boons, A.B. Ward, M.H. Verheije, R.P. de Vries. 2019. Fluorescent trimeric hemagglutinins reveal multivalent receptor binding properties. J. Mol. Biol. 431(4): 842-856.  [PMID: 30597163]

Hulswit, R.J.G., Y.F. Lang, M.J.G. Bakkers, W.T. Li, Z.S. Li, A. Schouten, B. Ophorst, F.J.M. van Kuppeveld, G.J. Boons, B.J. Bosch, E.G. Huizinga, R.J. de Groot. 2019. Human coronaviruses OC43 and HKU1 bind to 9-O-acetylated sialic acids via a conserved receptor-binding site in spike protein domain A. Proc. Natl. Acad. Sci. U. S. A. 116(7): 2681-2690.  [PMID: 30679277]

Thompson, A.J., R.P. de Vries, J.C. Paulson. 2019. Virus recognition of glycan receptors. Curr. Opin. Virol. 34: 117-129.  [PMID: 30849709]

Liu, L., A.R. Prudden, C.J. Capicciotti, G.P. Bosman, J.Y. Yang, D.G. Chapla, K.W. Moremen, G.J. Boons. 2019. Streamlining the chemoenzymatic synthesis of complex N-glycans by a stop and go strategy. Nat. Chem. 11(2): 161-169.  [PMID: 30532014]

Marcelo, F., N. Supekar, F. Corzana, J.C. van der Horst, I.M. Vuist, D. Live, G.P.H. Boons, D.F. Smith, S.J. van Vliet. 2019. Identification of a secondary binding site in human macrophage galactose-type lectin by microarray studies: Implications for the molecular recognition of its ligands. J. Biol. Chem. 294(4): 1300-1311.  [PMID: 30504228]

Mukherjee, R., M. van de Kaa, J. Garssen, R.J. Pieters, A.D. Kraneveld, L.E.M. Willemsen. 2019. Lactulose synergizes with CpG-ODN to modulate epithelial and immune cells cross talk. Food Funct 10(1): 33-37.  [PMID: 30632580]

Shi, H., W.N. Leonhard, N.J. Sijbrandi, M.J. van Steenbergen, M. Fens, J.B. van de Dikkenberg, J.S. Torano, D.J.M. Peters, W.E. Hennink, R.J. Kok. 2019. Folate-dactolisib conjugates for targeting tubular cells in polycystic kidneys. J. Control Release 293: 113-125.  [PMID: 30472374]

Chapman, R.N., L. Liu, G.J. Boons. 2018. 4,6- O-Pyruvyl ketal modified N-acetylmannosamine of the secondary cell wall polysaccharide of Bacillus anthracis is the anchoring residue for its surface layer proteins. J. Am. Chem. Soc. 140(49): 17079–17085.  [PMID: 30452253]

Shi, J., R. Ruijtenbeek, R.J. Pieters. 2018. Demystifying O-GlcNAcylation: hints from peptide substrates. Glycobiology 28(11): 814-824.  [PMID: 29635275]

Du, W., M. Dai, Z. Li, G.J. Boons, B. Peeters, F.J.M. van Kuppeveld, E. de Vries, C.A.M. de Haan. 2018. Substrate binding by the second sialic acid-binding site of influenza A virus N1 neuraminidase contributes to enzymatic activity. J. Virol. 92(20): e01243-01218.  [PMID: 30089692]

Moure, M.J., A. Eletsky, Q. Gao, L.C. Morris, J.Y. Yang, D. Chapla, Y. Zhao, C. Zong, I.J. Amster, K.W. Moremen, G.J. Boons, J.H. Prestegard. 2018. Paramagnetic tag for glycosylation sites in glycoproteins: Structural constraints on heparan sulfate binding to Robo1. ACS Chem. Biol. 13(9): 2560-2567.  [PMID: 30063822]

Yu, S.H., P. Zhao, P.K. Prabhakar, T. Sun, A. Beedle, G.J. Boons, K.W. Moremen, L. Wells, R. Steet. 2018. Defective mucin-type glycosylation on alpha-dystroglycan in COG-deficient cells increases its susceptibility to bacterial proteases. J. Biol. Chem. 293(37): 14534-14544.  [PMID: 30049793]

Yi, F., X. Hong, A.B. Kumar, C. Zong, G.J. Boons, C.R. Scott, F. Turecek, B.H. Robinson, M.H. Gelb. 2018. Detection of mucopolysaccharidosis III-A (Sanfilippo Syndrome-A) in dried blood spots (DBS) by tandem mass spectrometry. Mol. Genet. Metab. 125(1-2): 59-63.  [PMID: 30006231]

Guardiola, S., R. Prades, L. Mendieta, A.J. Brouwer, J. Streefkerk, L. Nevola, T. Tarrago, R.M.J. Liskamp, E. Giralt. 2018. Targeted covalent inhibition of prolyl oligopeptidase (POP): Discovery of sulfonylfluoride peptidomimetics. Cell Chem. Biol. 25(8): 1031-1037.  [PMID: 29779956]

Liang, Q., P. Chopra, G.J. Boons, J.S. Sharp. 2018. Improved de novo sequencing of heparin/heparan sulfate oligosaccharides by propionylation of sites of sulfation. Carbohydr. Res. 465: 16-21.  [PMID: 29920400]

Martínez-Jothar, L., S. Doulkeridou, R.M. Schiffelers, J. Sastre Toraño, S. Oliveira, C.F. van Nostrum, W.E. Hennink. 2018. Insights into maleimide-thiol conjugation chemistry: Conditions for efficient surface functionalization of nanoparticles for receptor targeting. J. Control. Release 282: 101-109.  [PMID: 29526739]

Hogan, J.D., J.A. Klein, J. Wu, P. Chopra, G.J. Boons, L. Carvalho, C. Lin, J. Zaia. 2018. Software for peak finding and elemental composition assignment for glycosaminoglycan tandem mass spectra. Mol. Cell. Proteomics 17(7): 1448-1456.  [PMID: 29615495]

Chevtchik, N.V., M. Mihajlovic, M. Fedecostante, L. Bolhuis-Versteeg, J. Sastre Toraño, R. Masereeuw, D. Stamatialis. 2018. A bioartificial kidney device with polarized secretion of immune modulators. J. Tissue Eng. Regen. Med. 12(7): 1670-1678.  [PMID: 29764003]

Artschwager, R., D.J. Ward, S. Gannon, A.J. Brouwer, H. van de Langemheen, H. Kowalski, R.M.J. Liskamp. 2018. Potent and highly selective inhibitors of the proteasome trypsin-like site by incorporation of basic side chain containing amino acid derived sulfonyl fluorides. J. Med. Chem. 61(12): 5395-5411.  [PMID: 29782167]

Chinoy, Z.S., F. Friscourt, C.J. Capicciotti, P. Chiu, G.J. Boons. 2018. Chemoenzymatic synthesis of asymmetrical multi-antennary N-glycans to dissect glycan-mediated interactions between human sperm and oocytes. Chem. Eur. J. 24(31): 7970-7975.  [PMID: 29603480]

Zhao, Y., J.Y. Yang, D.F. Thieker, Y. Xu, C. Zong, G.J. Boons, J. Liu, R.J. Woods, K.W. Moremen, I.J. Amster. 2018. A traveling wave ion mobility spectrometry (TWIMS) study of the Robo1-heparan sulfate interaction. J. Am. Soc. Mass Spectrom. 29(6): 1153-1165.  [PMID: 29520710]

Wu, J., J. Wei, J.D. Hogan, P. Chopra, A. Joshi, W. Lu, J. Klein, G.J. Boons, C. Lin, J. Zaia. 2018. Negative electron transfer dissociation sequencing of 3-O-sulfation-containing heparan sulfate oligosaccharides. J. Am. Soc. Mass Spectrom. 29(6): 1262-1272.  [PMID: 29564812]

van Heugten, A.J.P., W. de Boer, W.S. de Vries, R.J. Pieters, H. Vromans. 2018. Topically used corticosteroids: What is the big picture of drug product degradation? Eur. J. Pharm. Sci. 117: 1-7.  [PMID: 29407556]

Peng, W., K.M. Bouwman, R. McBride, O.C. Grant, R.J. Woods, M.H. Verheije, J.C. Paulson, R.P. de Vries. 2018. Enhanced human-type receptor binding by ferret-transmissible H5N1 with a K193T mutation. J. Virol. 92(10): pii: JVI.02016-02017.  [PMID: 29491160]

Kordalivand, N., D.D. Li, N. Beztsinna, J. Sastre Toraño, E. Mastrobattista, C.F. van Nostrum, W.E. Hennink, T. Vermonden. 2018. Polyethyleneimine coated nanogels for the intracellular delivery of RNase A for cancer therapy. Chem. Eng. J. 340: 32-41.

Lu, W., C. Zong, P. Chopra, L.E. Pepi, Y. Xu, I.J. Amster, J. Liu, G.J. Boons. 2018. Controlled chemoenzymatic synthesis of heparan sulfate oligosaccharides. Angew. Chem. Int. Ed. 57(19): 5340-5344.  [PMID: 29512241]

Zhang, H., T. Tomasic, J. Shi, M. Weiss, R. Ruijtenbeek, M. Anderluh, R.J. Pieters. 2018. Inhibition of O-GlcNAc transferase (OGT) by peptidic hybrids. MedChemComm 9(5): 883-887.  [PMID: 30108977]

Kadirvelraj, R., J.Y. Yang, J.H. Sanders, L. Liu, A. Ramiah, P.K. Prabhakar, G.J. Boons, Z.A. Wood, K.W. Moremen. 2018. Human N-acetylglucosaminyltransferase II substrate recognition uses a modular architecture that includes a convergent exosite. Proc. Natl. Acad. Sci. U. S. A. 115(18): 4637-4642.  [PMID: 29666272]

Zhang, H., D. Laaf, L. Elling, R.J. Pieters. 2018. Thiodigalactoside-bovine serum albumin conjugates as high-potency inhibitors of Galectin-3: An outstanding example of multivalent presentation of small molecule inhibitors. Bioconjug. Chem. 29(4): 1266-1275.  [PMID: 29474087]

Sychantha, D., R.N. Chapman, N.C. Bamford, G.J. Boons, P.L. Howell, A.J. Clarke. 2018. Molecular basis for the attachment of S-layer proteins to the cell wall of Bacillus anthracis. Biochemistry 57(13): 1949-1953.  [PMID: 29522326]

van Heugten, A.J.P., W.S. de Vries, M.M.A. Markesteijn, R.J. Pieters, H. Vromans. 2018. The role of excipients in the stability of triamcinolone acetonide in ointments. AAPS PharmSciTech 19(3): 1448-1453.  [PMID: 29450828]

Mena-Barragán, T., M.I. García-Moreno, A. Sevšek, T. Okazaki, E. Nanba, K. Higaki, N.I. Martin, R.J. Pieters, J.M.G. Fernández, C.O. Mellet. 2018. Probing the Inhibitor versus chaperone properties of sp(2)-Iminosugars towards human beta-glucocerebrosidase: A picomolar chaperone for Gaucher disease. Molecules 23(4).  [PMID: 29673163]

Williams, C., F. Royo, O. Aizpurua-Olaizola, R. Pazos, G.J. Boons, N.C. Reichardt, J.M. Falcon-Perez. 2018. Glycosylation of extracellular vesicles: current knowledge, tools and clinical perspectives. J. Extracell. Vesicles 7(1).  [PMID: 29535851]

Aizpurua-Olaizola, O., J. Sastre Toraño, J.M. Falcon-Perez, C. Williams, N. Reichardt, G.J. Boons. 2018. Mass spectrometry for glycan biomarker discovery. Trends Anal. Chem. 100: 7-14.

Haataja, S., P. Verma, O. Fu, A.C. Papageorgiou, S. Poysti, R.J. Pieters, U.J. Nilsson, J. Finne. 2018. Rationally designed chemically modified glycodendrimer inhibits Streptococcus suis adhesin SadP at picomolar concentrations. Chem. Eur. J. 24(8): 1905-1912.  [PMID: 29094420]

Brittoli, A., S. Fallarini, H. Zhang, R.J. Pieters, G. Lombardi. 2018. "In vitro" studies on galectin-3 in human natural killer cells. Immunol. Lett. 194: 4-12.  [PMID: 29248489]

Supekar, N.T., V. Lakshminarayanan, C.J. Capicciotti, A. Sirohiwal, C.S. Madsen, M.A. Wolfert, P.A. Cohen, S.J. Gendler, G.J. Boons. 2018. Synthesis and immunological evaluation of a multicomponent cancer vaccine candidate containing a long MUC1 glycopeptide. ChemBioChem 19(2): 121-125.  [PMID: 29120508]

Stel, M.H., R.J. Pieters. Blocking disease linked lectins with multivalent carbohydrates. In: Huskens J, Prins LJ, Haag R, Ravoo BJ, editors. Multivalency - Concepts, Research & Applications. Hoboken, New Jersey: Wiley, Inc.; 2018. p. 345-380.

Sychantha, D., D.J. Little, R.N. Chapman, G.J. Boons, H. Robinson, P.L. Howell, A.J. Clarke. 2018. PatB1 is an O-acetyltransferase that decorates secondary cell wall polysaccharides. Nat. Chem. Biol. 14(1): 79-85.  [PMID: 29083419]

Aizpurua-Olaizola, O., J. Sastre Toraño, A. Pukin, O. Fu, G.J. Boons, G.J. de Jong, R.J. Pieters. 2018. Affinity capillary electrophoresis for the assessment of binding affinity of carbohydrate-based cholera toxin inhibitors. Electrophoresis 39(2): 344-347.  [PMID: 28905402]

Kleijn, L.H.J., H.C. Vlieg, T.M. Wood, J. Sastre Toraño, B.J.C. Janssen, N.I. Martin. 2017. A high-resolution crystal structure that reveals molecular details of target recognition by the calcium-dependent lipopeptide antibiotic Laspartomycin C. Angew. Chem. Int. Ed. 56(52): 16546-16549.  [PMID: 29108098]

Yoshisada, R., L. van Gijzel, S.A.K. Jongkees. 2017. Towards tuneable retaining glycosidase-inhibiting peptides by mimicry of a plant flavonol warhead. ChemBioChem 18(23): 2333-2339.  [PMID: 28984404]

Yang, X., L.P. Beroske, J. Kemmink, D.T.S. Rijkers, R.M.J. Liskamp. 2017. Synthesis of bicyclic tripeptides inspired by the ABC-ring system of vancomycin through ruthenium-based cyclization chemistries. Tetrahedron Lett. 58(48): 4542-4546.

Moure, M.J., Y. Zhuo, G.J. Boons, J.H. Prestegard. 2017. Perdeuterated and (13)C-enriched myo-inositol for DNP assisted monitoring of enzymatic phosphorylation by inositol-3-kinase. Chem. Commun. 53(92): 12398-12401.  [PMID: 29067365]

Liu, L., A.R. Prudden, G.P. Bosman, G.J. Boons. 2017. Improved isolation and characterization procedure of sialylglycopeptide from egg yolk powder. Carbohydr. Res. 452: 122-128.  [PMID: 29096185]

Klamer, Z., B. Staal, A.R. Prudden, L. Liu, D.F. Smith, G.J. Boons, B. Haab. 2017. Mining high-complexity motifs in glycans: a new language to uncover the fine specificities of lectins and glycosidases. Anal. Chem. 89(22): 12342-12350.  [PMID: 29058413]

Benedetti, E., M. Pucic-Bakovic, T. Keser, A. Wahl, A. Hassinen, J.Y. Yang, L. Liu, I. Trbojevic-Akmacic, G. Razdorov, J. Stambuk, L. Klaric, I. Ugrina, M.H.J. Selman, M. Wuhrer, I. Rudan, O. Polasek, C. Hayward, H. Grallert, K. Strauch, A. Peters, T. Meitinger, C. Gieger, M. Vilaj, G.J. Boons, K.W. Moremen, T. Ovchinnikova, N. Bovin, S. Kellokumpu, F.J. Theis, G. Lauc, J. Krumsiek. 2017. Network inference from glycoproteomics data reveals new reactions in the IgG glycosylation pathway. Nat. Commun. 8(1): 1483.  [PMID: 29133956]

Sevšek, A., J. Sastre Toraño, L.C. Quarles van Ufford, E.E. Moret, R.J. Pieters, N.I. Martin. 2017. Orthoester functionalized N-guanidino derivatives of 1,5-dideoxy-1,5-imino-d-xylitol as pH-responsive inhibitors of beta-glucocerebrosidase. MedChemComm 8(11): 2050-2054.  [PMID: 30108721]

Lahav, D., B. Liu, R. van den Berg, A. van den Nieuwendijk, T. Wennekes, A.T. Ghisaidoobe, I. Breen, M.J. Ferraz, C.L. Kuo, L. Wu, P.P. Geurink, H. Ovaa, G.A. van der Marel, M. van der Stelt, R.G. Boot, G.J. Davies, J. Aerts, H.S. Overkleeft. 2017. A fluorescence polarization activity-based protein profiling assay in the discovery of potent, selective inhibitors for human nonlysosomal glucosylceramidase. J. Am. Chem. Soc. 139(40): 14192-14197.  [PMID: 28937220]

Fiers, M., J. Hoogenboom, A. Brunazzi, T. Wennekes, G.C. Angenent, R.G.H. Immink. 2017. A plant-based chemical genomics screen for the identification of flowering inducers. Plant Methods 13: 78.  [PMID: 29026434]

Capicciotti, C.J., C. Zong, M.O. Sheikh, T. Sun, L. Wells, G.J. Boons. 2017. Cell-surface glyco-engineering by exogenous enzymatic transfer using a bifunctional CMP-Neu5Ac derivative. J. Am. Chem. Soc. 139(38): 13342-13348.  [PMID: 28858492]

Gagarinov, I.A., A.D. Srivastava, G.J. Boons, Z. Wang. A multigram synthesis of phenyl 2-azido-3-O-benzyl-2-deoxy-4,6-O-benzylidene-1-thio-α-D-mannopyranoside. In: Vogel C, Murphy P, editors. Carbohydrate Chemistry: Proven Synthetic Methods. Boca Raton, FL: CRC Press, Taylor & Francis Group; 2017. p. Chapter 21.

Gagarinov, I.A., A.D. Srivastava, G.J. Boons, S. Visansirikul. Simplifying access to 3,4-di-O-acetyl-D-fucal. In: Vogel C, Murphy P, editors. Carbohydrate Chemistry: Proven Synthetic Methods. Boca Raton, FL: CRC Press, Taylor & Francis Group; 2017. p. Chapter 24.

Sharif, S., J. Shi, M. Bourakba, R. Ruijtenbeek, R.J. Pieters. 2017. Measuring O-GlcNAc cleavage by OGA and cell lysates on a peptide microarray. Anal. Biochem. 532: 12-18.  [PMID: 28571750]

Mackus, M., A.J.A.E. van de Loo, S.J. Raasveld, A. Hogewoning, J. Sastre Toraño, F.M. Flesch, G.A.H. Korte-Bouws, R.H.P. van Neer, X. Wang, T.T. Nguyen, K.A. Brookhuis, A.D. Kraneveld, J. Garssen, J.C. Verster. 2017. Biomarkers of the alcohol hangover state: Ethyl glucuronide (EtG) and ethyl sulfate (EtS). Hum. Psychopharmacol. 32(5).  [PMID: 28685869]

de Vries, R.P., N. Tzarum, W. Peng, A.J. Thompson, I.N. Ambepitiya Wickramasinghe, A.T.T. de la Pena, M.J. van Breemen, K.M. Bouwman, X. Zhu, R. McBride, W. Yu, R.W. Sanders, M.H. Verheije, I.A. Wilson, J.C. Paulson. 2017. A single mutation in Taiwanese H6N1 influenza hemagglutinin switches binding to human-type receptors. EMBO Mol. Med. 9(9): 1314-1325.  [PMID: 28694323]

Agyekum, I., C. Zong, G.J. Boons, I.J. Amster. 2017. Single stage tandem mass spectrometry assignment of the C-5 uronic acid stereochemistry in heparan sulfate tetrasaccharides using electron detachment dissociation. J. Am. Soc. Mass Spectrom. 28(9): 1741-1750.  [PMID: 28389983]

Gahtory, D., M. Murtola, M.M.J. Smulders, T. Wennekes, H. Zuilhof, R. Stromberg, B. Albada. 2017. Facile functionalization of peptide nucleic acids (PNAs) for antisense and single nucleotide polymorphism detection. Org. Biomol. Chem. 15(32): 6710-6714.  [PMID: 28766647]

van de Wakker, S.I., M.J.E. Fischer, R.S. Oosting. 2017. New drug-strategies to tackle viral-host interactions for the treatment of influenza virus infections. Eur. J. Pharmacol. 809: 178-190.  [PMID: 28533172]

van Haren, M.J., R. Taig, J. Kuppens, J. Sastre Toraño, E.E. Moret, R.B. Parsons, D. Sartini, M. Emanuelli, N.I. Martin. 2017. Inhibitors of nicotinamide N-methyltransferase designed to mimic the methylation reaction transition state. Org. Biomol. Chem. 15(31): 6656-6667.  [PMID: 28758655]

Ding, N., X. Li, Z.S. Chinoy, G.J. Boons. 2017. Synthesis of a glycosylphosphatidylinositol anchor derived from Leishmania donovani that can be functionalized by Cu-catalyzed azide-alkyne cycloadditions. Org. Lett. 19(14): 3827-3830.  [PMID: 28696125]

Zong, C., A. Venot, X. Li, W. Lu, W. Xiao, J.L. Wilkes, C.L. Salanga, T.M. Handel, L. Wang, M.A. Wolfert, G.J. Boons. 2017. Heparan sulfate microarray reveals that heparan sulfate-protein binding exhibits different ligand requirements. J. Am. Chem. Soc. 139(28): 9534-9543.  [PMID: 28651046]

Lin, A.E., C.A. Autran, A. Szyszka, T. Escajadillo, M. Huang, K. Godula, A.R. Prudden, G.J. Boons, A.L. Lewis, K.S. Doran, V. Nizet, L. Bode. 2017. Human milk oligosaccharides inhibit growth of group B Streptococcus. J. Biol. Chem. 292(27): 11243-11249.  [PMID: 28416607]

Prudden, A.R., L. Liu, C.J. Capicciotti, M.A. Wolfert, S. Wang, Z. Gao, L. Meng, K.W. Moremen, G.J. Boons. 2017. Synthesis of asymmetrical multiantennary human milk oligosaccharides. Proc. Natl. Acad. Sci. U. S. A. 114(27): 6954-6959.  [PMID: 28630345]

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Movahedin, M., T.M. Brooks, N.T. Supekar, N. Gokanapudi, G.J. Boons, C.L. Brooks. 2017. Glycosylation of MUC1 influences the binding of a therapeutic antibody by altering the conformational equilibrium of the antigen. Glycobiology 27(7): 677-687.  [PMID: 28025250]

de Vries, R.P., W. Peng, O.C. Grant, A.J. Thompson, X. Zhu, K.M. Bouwman, A.T.T. de la Pena, M.J. van Breemen, I.N. Ambepitiya Wickramasinghe, C.A.M. de Haan, W. Yu, R. McBride, R.W. Sanders, R.J. Woods, M.H. Verheije, I.A. Wilson, J.C. Paulson. 2017. Three mutations switch H7N9 influenza to human-type receptor specificity. PLoS Pathog. 13(6): e1006390.  [PMID: 28617868]

Tzarum, N., R.P. de Vries, W. Peng, A.J. Thompson, K.M. Bouwman, R. McBride, W. Yu, X. Zhu, M.H. Verheije, J.C. Paulson, I.A. Wilson. 2017. The 150-loop restricts the host specificity of human H10N8 influenza virus. Cell Rep. 19(2): 235-245.  [PMID: 28402848]

Sevšek, A., L. Srot, J. Rihter, M. Celan, L.C. Quarles van Ufford, E.E. Moret, N.I. Martin, R.J. Pieters. 2017. N-guanidino derivatives of 1,5-dideoxy-1,5-imino-d-xylitol are potent, selective, and stable inhibitors of beta-glucocerebrosidase. ChemMedChem 12(7): 483-486.  [PMID: 28328014]

Jongkees, S.A.K., S. Caner, C. Tysoe, G.D. Brayer, S.G. Withers, H. Suga. 2017. Rapid discovery of potent and selective glycosidase-inhibiting de novo peptides. Cell Chem. Biol. 24(3): 381-390.  [PMID: 28262556]

Dhamale, O.P., R. Lawrence, E.M. Wiegmann, B.A. Shah, K. Al-Mafraji, W.C. Lamanna, T. Lubke, T. Dierks, G.J. Boons, J.D. Esko. 2017. Arylsulfatase K is the lysosomal 2-sulfoglucuronate sulfatase. ACS Chem. Biol. 12(2): 367-373.  [PMID: 28055182]

Halmo, S.M., D. Singh, S. Patel, S. Wang, M. Edlin, G.J. Boons, K.W. Moremen, D. Live, L. Wells. 2017. Protein O-linked mannose beta-1,4-N-acetylglucosaminyltransferase 2 (POMGNT2) is a gatekeeper enzyme for functional glycosylation of alpha-dystroglycan. J. Biol. Chem. 292(6): 2101-2109.  [PMID: 27932460]

Parsons, L.M., Y. An, R.P. de Vries, C.A. de Haan, J.F. Cipollo. 2017. Glycosylation characterization of an influenza H5N7 hemagglutinin series with engineered glycosylation patterns: Implications for structure-function relationships. J. Proteome Res. 16(2): 398-412.  [PMID: 28060516]

Jongkees, S.A.K., S. Umemoto, H. Suga. 2017. Linker-free incorporation of carbohydrates into in vitro displayed macrocyclic peptides. Chem. Sci. 8(2): 1474-1481.  [PMID: 28572907]

Gagarinov, I.A., T. Li, J.S. Torano, T. Caval, A.D. Srivastava, J.A. Kruijtzer, A.J. Heck, G.J. Boons. 2017. Chemoenzymatic approach for the preparation of asymmetric bi-, tri-, and tetra-antennary N-glycans from a common precursor. J. Am. Chem. Soc. 139(2): 1011-1018.  [PMID: 28002670]

Peng, W., R.P. de Vries, O.C. Grant, A.J. Thompson, R. McBride, B. Tsogtbaatar, P.S. Lee, N. Razi, I.A. Wilson, R.J. Woods, J.C. Paulson. 2017. Recent H3N2 viruses have evolved specificity for extended, branched human-type receptors, conferring potential for increased avidity. Cell Host Microbe 21(1): 23-34.  [PMID: 28017661]

Zhao, Y., A. Singh, Y. Xu, C. Zong, F. Zhang, G.J. Boons, J. Liu, R.J. Linhardt, R.J. Woods, I.J. Amster. 2017. Gas-phase analysis of the complex of fibroblast growthfactor 1 with heparan sulfate: A traveling wave ion mobility spectrometry (TWIMS) and molecular modeling study. J. Am. Soc. Mass Spectrom. 28(1): 96-109.  [PMID: 27663556]

Li, T., M. Huang, L. Liu, S. Wang, K.W. Moremen, G.J. Boons. 2016. Divergent chemoenzymatic synthesis of asymmetrical-core-fucosylated and core-unmodified N-glycans. Chem. Eur. J. 22(52): 18742-18746.  [PMID: 27798819]

Dymek, K., V. Panarese, E. Herremans, D. Cantre, R. Schoo, J.S. Torano, H. Schluepmann, L. Wadso, P. Verboven, B.M. Nicolai, P. Dejmek, F. Gomez Galindo. 2016. Investigation of the metabolic consequences of impregnating spinach leaves with trehalose and applying a pulsed electric field. Bioelectrochemistry 112: 153-157.  [PMID: 26936113]

Sminia, T.J., H. Zuilhof, T. Wennekes. 2016. Getting a grip on glycans: A current overview of the metabolic oligosaccharide engineering toolbox. Carbohydr. Res. 435: 121-141.  [PMID: 27750120]

Gao, Q., C.Y. Chen, C. Zong, S. Wang, A. Ramiah, P. Prabhakar, L.C. Morris, G.J. Boons, K.W. Moremen, J.H. Prestegard. 2016. Structural aspects of heparan sulfate binding to Robo1-Ig1-2. ACS Chem. Biol. 11(11): 3106-3113.  [PMID: 27653286]

Card, D.J., R. Huisjes, K. Deuchande, P. Clarke, F.M. Flesch, D.J. Harrington. 2016. Measurement of vitamin K metabolites in neonatal faecal matter by HPLC with electrochemical detection. Curr. Chromatogr. 3(1): 24-33.

Singh, A., M.B. Tessier, K. Pederson, X.C. Wang, A.P. Venot, G.J. Boons, J.H. Prestegard, R.J. Woods. 2016. Extension and validation of the GLYCAM force field parameters for modeling glycosaminoglycans. Can. J. Chem. 94(11): 927-935.  [PMID: 28603292]

Hoogenboom, J., N. Berghuis, D. Cramer, R. Geurts, H. Zuilhof, T. Wennekes. 2016. Direct imaging of glycans in Arabidopsis roots via click labeling of metabolically incorporated azido-monosaccharides. BMC Plant Biol. 16(1): 220.  [PMID: 27724898]

Sevšek, A., M. Čelan, B. Erjavec, L.C. Quarles van Ufford, J. Sastre Toraño, E.E. Moret, R.J. Pieters, N.I. Martin. 2016. Bicyclic isoureas derived from 1-deoxynojirimycin are potent inhibitors of beta-glucocerebrosidase. Org. Biomol. Chem. 14(37): 8670-8673.  [PMID: 27604065]

Hoogenboom, J., M. Lutz, H. Zuilhof, T. Wennekes. 2016. Exploring the chemistry of bicyclic isoxazolidines for the multicomponent synthesis of glycomimetic building blocks. J. Org. Chem. 81(19): 8826-8836.  [PMID: 27583805]

Zong, C., R. Huang, E. Condac, Y. Chiu, W. Xiao, X. Li, W. Lu, M. Ishihara, S. Wang, A. Ramiah, M. Stickney, P. Azadi, I.J. Amster, K.W. Moremen, L. Wang, J.S. Sharp, G.J. Boons. 2016. Integrated approach to identify heparan sulfate ligand requirements of Robo1. J. Am. Chem. Soc. 138(39): 13059-13067.  [PMID: 27611601]

Boltje, T.J., L. Liu, G.J. Boons. Controlling anomeric selectivity, reactivity, and regioselectivity in glycosylations using protecting groups. In: Hung S-C, Zulueta MML, editors. Glycochemical Synthesis: Strategies and Applications: Wiley, Inc.; 2016. p. Chapter 4, 97-129.

Bode, L., N. Contractor, D. Barile, N. Pohl, A.R. Prudden, G.J. Boons, Y.S. Jin, S. Jennewein. 2016. Overcoming the limited availability of human milk oligosaccharides: challenges and opportunities for research and application. Nutr. Rev. 74(10): 635-644.  [PMID: 27634978]

van Haren, M.J., J. Sastre Toraño, D. Sartini, M. Emanuelli, R.B. Parsons, N.I. Martin. 2016. A rapid and efficient assay for the characterization of substrates and inhibitors of nicotinamide n-methyltransferase. Biochemistry 55(37): 5307-5315.  [PMID: 27570878]

Delaine, T., P. Collins, A. MacKinnon, G. Sharma, J. Stegmayr, V.K. Rajput, S. Mandal, I. Cumpstey, A. Larumbe, B.A. Salameh, B. Kahl-Knutsson, H. van Hattum, M. van Scherpenzeel, R.J. Pieters, T. Sethi, H. Schambye, S. Oredsson, H. Leffler, H. Blanchard, U.J. Nilsson. 2016. Galectin-3-binding glycomimetics that strongly reduce bleomycin-induced lung fibrosis and modulate intracellular glycan recognition. ChemBioChem 17(18): 1759-1770.  [PMID: 27356186]

Sun, T., S.H. Yu, P. Zhao, L. Meng, K.W. Moremen, L. Wells, R. Steet, G.J. Boons. 2016. One-step selective exoenzymatic labeling (SEEL) strategy for the biotinylation and identification of glycoproteins of living cells. J. Am. Chem. Soc. 138(36): 11575-11582.  [PMID: 27541995]

Prior, A., L. Sánchez-Hernández, J. Sastre-Toraño, M.L. Marina, G.J. de Jong, G.W. Somsen. 2016. Enantioselective analysis of proteinogenic amino acids in cerebrospinal fluid by capillary electrophoresis-mass spectrometry. Electrophoresis 37(17-18): 2410-2419.  [PMID: 27465690]

Brouwer, A.J., N. Herrero Alvarez, A. Ciaffoni, H. van de Langemheen, R.M. Liskamp. 2016. Proteasome inhibition by new dual warhead containing peptido vinyl sulfonyl fluorides. Bioorg. Med. Chem. 24(16): 3429-3435.  [PMID: 27316540]

Li, X., S.J. Martin, Z.S. Chinoy, L. Liu, B. Rittgers, R.A. Dluhy, G.J. Boons. 2016. Label-free detection of glycan-protein interactions for array development by surface enhanced Raman spectroscopy (SERS). Chem. Eur. J. 22(32): 11180-11185.  [PMID: 27304194]

Zomer-van Ommen, D.D., A.V. Pukin, O. Fu, L.C. Quarles van Ufford, H.M. Janssens, J.M. Beekman, R.J. Pieters. 2016. Functional characterization of cholera toxin inhibitors using human intestinal organoids. J. Med. Chem. 59(14): 6968-6972.  [PMID: 27347611]

Alaarg, A., K.H. Zheng, F.M. van der Valk, A.E. da Silva, M. Versloot, L.C. Quarles van Ufford, D.M. Schulte, G. Storm, J.M. Metselaar, E.S. Stroes, A.A. Hamers. 2016. Multiple pathway assessment to predict anti-atherogenic efficacy of drugs targeting macrophages in atherosclerotic plaques. Vascul. Pharmacol. 82: 51-59.  [PMID: 27189780]

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