Bijvoet Seminars

The Bijvoet Center organizes regular Bijvoet Seminars. An external scientist is invited to present his research to the students, postdocs and staff of the Center. All seminars are announced via the mailinglist of the Bijvoet Center. You can join the general Bijvoet mailinglist here

Previous speakers include:

Seminars in 2018

  • Francesca Mattiroli - Evolution and assembly of eukaryotic chromatin (17 Apr, 2018)
  • Cédric Govaerts - Conformational dynamics of CFTR revealed by stabilizing nanobodies (20 Jun, 2018)

Seminars in 2017

  • Ming-Daw Tsai – How DNA polymerases catalyze replication and repair with contrasting fidelity (26 Sep, 2017)
  • Frans Mulder – Protein unfolding under pressure (19 Oct, 2017)
  • Modesto Orozco – On the predictive power of MD simulations on DNA (31 Oct, 2017)
  • Radu Aricescu – Structural Insights into GABAA Receptor Gating Mechanisms (9 Nov, 2017)

Seminars in 2016

  • Teresa Carlomagno – RNA-protein complexes in RNA metabolism: an integrative structural biology approach (10 Mar, 2016)
  • Philipp Selenko – Looking at proteins in live cells with atomic-resolution: From Science Fiction to Science Reality (24 Mar, 2016)
  • Manuel Etzkorn – Conventional and non-conventional methods for the NMR characterization of (membrane-) protein structure, folding and function (12 Apr, 2016)
  • Björn Burmann – Membrane-protein–chaperone complexes: Elucidating the functional detailsby NMR and AFM (12 Apr, 2016)
  • Hugo van Ingen – Unpinning chromatin: casting shadows of nucleosomes by NMR (22 Apr, 2016)
  • Jana Broecker – Advances in membrane-protein crystallization: From detergent-free crystallization to in situ approaches (22 Apr, 2016)

Seminars in 2015

  • Nicki Packer – Glycomics: the new -omics (13 Mar, 2015)
  • Alan Mark – Activation of cytokine receptors and transport proteins: Turning on micromachines (31 Mar, 2015)
  • Juliane Liepe – Computational models as microscopes: rate-limiting steps in proteasomes (19 May, 2015)
  • Friedrich Förster – Cotranslational protein translocation and membrane insertion in situ (19 May, 2015)
  • Niels de Jonge – Electron microscopy of labeled membrane proteins in whole eukaryotic cells in liquid (20 May, 2015)
  • Chris Abell – Fragment-based approaches in drug discovery and chemical biology (28 Aug, 2015)
  • Katja Petzold – Characterizing Transient Structures of RNA using NMR (10 Sep, 2015)
  • John Briggs – Structure in situ: (cryo-)electron microscopy of viruses and vesicles (1 Oct, 2015)
  • Sandro Keller – Electrostatics trumps hydrophobicity: how to fold a hydrophilic membrane protein (19 Nov, 2015)

Seminars in 2014

  • Daniel Southworth – Architecture and control mechanisms of nitric oxide synthases: essential regulators of mammalian physio (11 Mar, 2014)
  • Henry van den Bedem – Characterizing Biomolecular Ensembles with Molecular-Scale Kinematics (2 Jul, 2014)
  • Remco Sprangers – Detection and analysis of motions in large molecular complexes using novel methods in NMR spectroscopy (22 Sep, 2014)
  • Eduardo Perozo – Structural basis of voltage-dependent gating in ion channels and enzymes (28 Oct, 2014)
  • Yvonne Jones – Norrin and Notum: some new structural insights for the Wnt signalling system (12 Nov, 2014)
  • Kevin H. Mayo – “Galectins: Their Interactions with Polysaccharides and Structure-Based Design of Antagonists for the Clinic (10 Dec, 2014)

Seminars in 2013

  • David Schriemer – Structural Mass Spectrometry of Complex Protein Systems (28 Jan, 2013)
  • Juan Fernández-Recio – Protein-protein docking challenges in the interactomics era (5 Feb, 2013)
  • Dirk Görlich – Transport through nuclear pores: the jelly path (Sep 9, 2013)
  • Lyndon Emsley – Surface enhanced NMR spectroscopy (Oct 3, 2013)
  • Fraydoon Rastinejad – Nuclear hormone receptors and metabolic pathways (Nov 22, 2013)

Seminars in 2012

  • Tim Cross – The Influence of Membrane Mimetic Environments on Membrane Protein Structures: M2 Protein and Others (27 Mar, 2012)
  • Wim Hol – Towards understanding the sophisticated two-membrane-spanning Type II Secretion System (13 Apr, 2012)
  • Imre Berger – Towards Eukaryotic Structural Complexomics (8 May, 2012)
  • Katie Henzler-Wildman – Conformational Exchange and the Mechanism of Multidrug Resistant Transport by EmrE (14 May, 2012)
  • Erik Zuiderweg – Non-canonical ligand-binding events as detected by NMR (22 May, 2012)
  • Changlin Tian – Structural Studies of Outer Membrane “Channel” proteins of Mycobactrium tuberculosis (16 Aug, 2012)
  • Debora Marks – Evolutionary co-variation from genomic sequencing reveals 3D protein structure and function (11 Sep, 2012)
  • Andrew Baldwin – Probing the structure, dynamics, and function of complex systems with NMR, ion mobility mass spectromety, electron microscopy and Rosetta: application to the human chaperone alphaB-crystallin (23 Nov, 2012)
  • Leonard Foster – Measuring the response of the interactome and phosphoproteome to bacterial infection (27 Nov, 2012)
  • Alfred Vertegaal – Cracking the SUMO signalling code (27 Nov, 2012)

Seminars in 2011

  • Liesbeth Veenhoff – Transport of membrane proteins through the nuclear pore complex requires long fl­exible linker (10 Feb, 2011)
  • Peter Tieleman – Watching lipids move: computer simulations of defects, flip-flop, and fusion (4 Apr, 2011)
  • Trevor Douglas – Viruses: Natural Supramolecular Architectures and Synthetic Building Blocks (8 Apr, 2011)
  • Henk Stunnenberg –  ‘systems biology’ to gain molecular insight into differentiation and transformation pathways (14 Apr, 2011)
  • Rob Russell – Predicting structure and mechanism in biological interaction networks (17 May, 2011)
  • Alain Milon – Structure and dynamics of membrane components (sterols, peptides and proteins) by liquid and solid state NMR (23 May, 2011)
  • Randy Read – Structures of a redox switch modulating blood pressure: angiotensinogen and renin (23 May, 2011)
  • Alan E. Mark – Atomistic models of biomolecular systems: The search for certainty in an uncertain world (15 Sep, 2011)
  • Ljiljana Pasa-Tolic – Towards Quantitative Intact Protein Mass Spectrometry (14 Oct, 2011)
  • Walter Chazin – Structural architecture and remodeling of modular multi-domain proteins in DNA processing machinery (19 Oct, 2011)
  • Anne S. Ulrich – Structure-function analysis of short antimicrobial peptides in membranes (7 Nov, 2011)
  • Tom Woolf – Molecular Dynamics Calculations of Conformational Changes in the Sarcoplasmic Reticulum Ca-ATPAse pump (SERCA) (1 Dec, 2011)
  • Vitali Tugarinov – Methyl-based NMR Evidence for Symmetry in Functionally or  Crystallographically Asymmetric Homodimers (12 Dec, 2011)

Seminars in 2010

  • Venki Ramakrishnan – What ribosome structures reveal about tRNA selection during decoding of mRNA (22 Jan, 2010)
  • Holger Stark – Ribosome dynamics and tRNA movement as visualized by time-resolved electron cryomicroscopy (5 Feb, 2010)
  • Peter Peters – Towards Visualization of Nanomachines in their Native Cellular Environment (12 Feb, 2010)
  • Sheena Radford – Molecular insights into protein self-assembly mechanisms in amyloid disease (26 Mar, 2010)
  • Martin Engelhard – Biophysics: Tools to answer biological questions in cellular signal transfer and Prion disease (16 Apr, 2010)
  • Maarten Merkx – Engineering protein switches for intracellular imaging and diagnostics (26 Apr, 2010)
  • Marloes Groot – Imaging the brain & Enzyme dynamics (31 May, 2010)
  • Beat Meier – Characterization of Fibrils and Prions by Solid-State NMR (29 June, 2010)
  • Ming Tan – Structural Basis of Norovirus-Host Interaction and Implications in Disease Control and Prevention (1 Oct, 2010)
  • Blake Wiedenheft – Biochemical and structural characterization of the CRISPR-cas immune system (RNAi-like) in prokaryotes (19 Oct, 2010)
  • Robert G. Griffin – MAS NMR Determination of the Structure of an Amyloid Fibril (26 Oct, 2010)

Seminars in 2008

  • Dino Moras – Nuclear Hormone Receptors: Structural basis for some functional features (8 Feb, 2008)
  • Patric Fuchs – Molecular insights into transmembrane peptides and surfactants dynamics from computer simulations (21 Feb, 2008)
  • Ariel Fernandez – Curbing drug side effects by exploiting integrative ideas in molecular biophysics (4 Mar, 2008)

Seminars in 2007

  • Hans Gerritsen – Non-linear excitation and spectroscopy in fluorescence microscopy (16 Feb, 2007)
  • Michael Zasloff – Antimicrobial peptides in human health and disease (8 Mar, 2007)
  • Dmitri Svergun – Analysis of Biomacromolecular Solutions with Small-Angle Scattering (1 Jun, 2007)
  • Thomas Kiefhaber – Fast Folding and Assembly of a Small Trimerization Domain from Phage T4 Fibritin (7 Dec, 2007)
  • Zihe Rao – Structural proteomics of the SARS coronavirus: structure, function and interaction of the replicase proteins (13 Dec, 2007)

Seminars in 2006

  • Gijs Wuite – A singular view of DNA transactions (31 Mar, 2006)
  • Petra Schwille – Probing the Local Micro-environment in Model and Cell Membranes on a Single Molecule Scale (12 May, 2006)
  • Jens Andersen – Organellar proteomics: turning inventories into insights. (29 Sep, 2006)
  • Steven O. Smith – Transmembrane Helix Interactions in Membrane Protein Structure, Function and Disease (20 Dec, 2006)

Seminars in 2005

  • Anthony Lee – Membranes: a game of two halves (16 Dec, 2005)
  • Geert-Jan Boons – Glycosidase inhibitors as novel cancer therapeutics (12 Oct, 2005)
  • Randy Hampton – Cellular Regulation by Protein Quality Control (27 Apr, 2005)

Seminars in 2004

  • Michael Sattler – NMR studies of molecular recognition and dynamics during spliceosome assembly and RNA interference (24 Sep, 2004)
  • Frank Sobott – Making elephants fly: Nano-ESI and tandem-MS for the characterisation of noncovalent protein complexes in the gas phase (24 Sep, 2004)
  • Colin Stirling – Co-ordination of Molecular Chaperones: many hands make light work! (2 Nov, 2004)
  • Catherine Etchebest – Escherichia coli mechanosensitive channel: Conformational changes and membrane environment (16 Dec, 2004)