Postdoc Neurotoxicology (0.8 – 1.0 FTE)

Hours per week: 
32 to 40
Faculty: 
Faculty of Veterinary Medicine
Department: 
Departement Population Health Sciences
Application deadline: 

Job description

At the Toxicology Division we aim to improve the scientific basis of chemical risk assessment through fundamental and applied innovative research and teaching in mechanistic toxicology and exposure assessment. We are looking for an enthusiastic, ambitious and creative postdoc to achieve these goals and strengthen our Toxicology Division.

You will be working in the Neurotoxicology Research Group. This research group is focused on investigating the cellular and molecular mechanisms of action of toxic substances on the (developing) nervous system using in vitro approaches. You will work mainly on the MOMENTUM project that aims to determine the effects of micro- and nanoplastic particles on human health. Specifically, you will investigate if micro- and nanoplastic particles can cross the blood-brain barrier and if these particles exert adverse effects on neuronal function and development. To that aim, you will cultivate and improve various in vitro models (cell lines, primary cultures, induced pluripotent stem cells) and you will use various techniques, ranging from biochemical assays to immunohistochemistry, cellular imaging (fluorescence microscopy) and microelectrode array (MEA) recordings to investigate neurotoxicity in vitro. In addition, part of your work will focus on developing (software) improvements for data analysis. We expect that teaching will also be part of the function in due course.

These activities will be closely aligned with parallel multi-disciplinary research efforts, such as the Virtual Human Platform for Safety Assessment, which is aimed at improving the prediction of the potential harmful effects of chemicals and pharmaceuticals by innovative animal-free safety assessment.

Qualifications

Candidates should have a PhD in the field of life and/or biomedical sciences, with a strong interest in cellular (neuro)toxicology and data-analysis. As our new colleague you are a motivated and collaborative team member with excellent verbal and written communication skills. You are able to work independently and have open mind for collaboration across scientific fields. Furthermore, you have experience with (neuronal) cell culture techniques, cellular imaging and/or electrophysiological techniques and data analyses. Experience with teaching and/or supervision of MSc-students/technicians is considered a plus.

Offer

We offer a temporary position (0.8 - 1.0 FTE) for one year. In case of a good performance an extension of 1 year is possible. The gross salary - depending on previous qualifications and experience  - ranges between €3,270 and €4,474 (scale 10 according to the Collective Labour Agreement Dutch Universities) per month for a full-time employment. Salaries are supplemented with a holiday bonus of 8% and a year-end bonus of 8.3% per year. In addition, Utrecht University offers excellent secondary conditions, including an attractive retirement scheme, (partly paid) parental leave and flexible employment conditions (multiple choice model). More information about working at Utrecht University can be found here.

About the organisation

A better future for everyone. This ambition motivates our scientists in executing their leading research and inspiring teaching. At Utrecht University, the various disciplines collaborate intensively towards major societal themes. Our focus is on Dynamics of Youth, Institutions for Open Societies, Life Sciences and Sustainability.

The Faculty of Veterinary Medicine has a unique position in the Netherlands. Not only is this the only institution where veterinarians are trained, researchers are also working together on innovative scientific research. In the coming years, the faculty will focus on three themes: One Health, One Medicine and Veterinary Biomedicine. In addition, the faculty provides specialist clinical care in the largest academic veterinary hospital in Europe. A focus on disease, health and well-being of animals and their environments underpins the faculty’s three main pillars: education, research, and veterinary health care. The faculty counts 1,500 students and 900 employees.

MOMENTUM is a project that aims to determine the effects of micro- and nanoplastic particles on human health. The tasks will be closely aligned with parallel multi-disciplinary research efforts, such as the Virtual Human Platform for Safety Assessment, which is aimed at improving the prediction of the potential harmful effects of chemicals and pharmaceuticals by innovative animal-free safety assessment.

Additional information

Would you like to know more about this position? Then please contact: Dr. Remco Westerink (Associate Professor), via r.westerink@uu.nl.

Apply

Everyone deserves to feel at home at our university. We welcome employees with a wide variety of backgrounds and perspectives.

Are you interested in applying? Send your motivation letter and CV using the application button below.

The application deadline is 21 January 2022.