Immunology

Besides the host’s perspective in the struggle with microbial invaders, immunology grasps the tolerance for the bodily constituents

Our research may contribute to solving problems of increasing global food demands, antibiotic resistance and increasing threats and burden caused by infectious and chronic inflammatory diseases. Applied aspects of the work relate to animal tuberculosis, avian influenza, canine atopic dermatitis, human autoimmune diseases, vaccine development and vaccine consistency testing.

Immunity to Microbes within the Cell
How does the immune system react to microbes within the cell? We explore the cellular mechanisms responsible for immune recognition of viruses and bacteria (pathogens) within the cell for the development of vaccines against microbes. Read more

Chronic Inflammatory Diseases
Our research focuses on immuno-modulation of chronic inflammatory diseases such as atopic dermatitis and ocular inflammation (uveitis) in dogs, rheumatoid arthritis and allergies in humans. Read more 

Avian Vaccine Strategies
How does the chicken immune system fight pathogens? Can we improve the development of the early immune system to get healthy chickens? How can knowledge on the chicken immune system contribute to vaccine development? Read more

Bovine Immunology
Cattle as production animal species suffer from several economically relevant infectious diseases, which may even have a zoonotic impact. Three of these, Staphylococcus aureus mastitis and the mycobacterial diseases Paratuberculosis (M. avium, subsp paratuberculosis) and Tuberculosis (M. bovis) have been subject of research for the last decade(s). Read more

Canine Immunology
Since several decades focus of research in this field, collaboration with the dermatologists of the Companion Animal Clinics, is on the immunopathogenesis of atopic dermatitis (AD) in dogs. Read more

Porcine immunology
What do we know about the immune system in pigs? How does it develop? Can we improve the pig immune system via a special diet? Are pigs a good model to study certain human diseases? Read more

Wildlife Immunology
Wildlife species, both free roaming and captive, at the human – livestock – wildlife interphase are amongst others prone to infection with mycobacteria of the Mycobacterium Tuberculosis Complex (MTBC) due to which they may develop tuberculosis. Read more