Micro-organisms are a constant challenge to human and animal health. There’s a delicate balance between bacteria, viruses, and parasites, and the immune system of animals and people. The increase in resistance to antibiotics poses one of the world’s major health care problems. The same applies to the emergence of novel (zoonotic) infectious viruses, such as influenza and coronaviruses, that can cause diseases. In Utrecht, we use a One Health approach to better understand the principles underlying infection and immunity in humans and animals. This knowledge could help to develop new drugs and vaccines to protect or cure patients from (fatal) infections, and may help to find answers to the global challenges of food safety and food security. . Read more...
28 February 2017
The Netherlands Antibiotic Development Platform (NADP) brings companies and research groups together to develop new antibiotics and alternatives.
Fungicidal Mechanisms of Cathelicidins LL-37 and CATH-2 Revealed by Live-Cell Imaging
Antifungal mechanisms of action of two cathelicidins, chicken CATH-2 and human LL-37, were studied and compared with the mode of action of the salivary peptide histatin 5 (Hst5). Read the full article.