Searching for 3Rs methods: a needle in a haystack?
According to the European Directive 2010/63/EU on the protection of animals used for scientific purposes, animal testing is not allowed unless there is no possible alternative. To ensure this, the principle of the 3Rs (Replacement, Reduction and Refinement) should be considered at all times (article 4). In order to implement the 3Rs, scientists have to be aware of the 3Rs methods available.
Scientists are familiar with searching for literature on their subject of interest. Searching specifically for 3Rs methods, however, is something which may require specific search skills. There is a lot of information available, so how to make sure you find everything you are looking for? With this article we hope to provide you with some tools that facilitate the search for 3Rs methods. This article is based on the EURL ECVAM Search Guide, which provides a search strategy for 3Rs methods and might be of great help.