Young Complexity Researchers’ Lunch (YCRL) #24: Quantifying spatial phenotypes of points with statistical models including rando
The monthly Young Complexity Research Lunch (YCRL) is organised by the open group for Young Complexity Researchers Utrecht (YCRU), consisting of PhD candidates and postdocs at UU. This community building lunch event is designed specifically for young complexity researchers to share their complex systems science related work in a relaxing and informal settings, and to provide the opportunity to discuss challenges in Complex Systems Studies.
Hereby, we cordially invite you to the Young Complexity Researchers’ Lunch (YCRL) #24 on Tuesday January 28 (12:30-13:00) by Kyriacos Nicolaou at the Centre for Complex Systems Studies (CCSS) where you can:
Get a free gourmet lunch with the best sandwiches you can get in the Utrecht Science Park;
Know one young complexity researchers' work over just 30 mins;
Contribute your professional knowledge and experiences in a relaxing and informal setting;
Develop potential collaboration.
Before the invited talk, the YCRU members come to together to go over the following agenda:
- Introduction of new members
- Catch-up round
- Upcoming events
- Scientific discussion (e.g. on topics like coding, career, literature, conference recap, poster presentation, new insights, feedback on own research)
Programme:
12:00-12:30 YCRU monthly meeting (all young complexity researchers are welcome, just walk in before 12:00).
12:30-13:00 YCRL #24 (everyone is welcome, please sign up below)
YCRL #24: Quantifying spatial phenotypes of points with statistical models including random fields
Leading young complexity researcher: Kyriacos Nicolaou (one of the current YCRU chairs), Biodynamics and Biocomplexity (UU)
Abstract:
Point patterns in biological systems often arise from complex interactions between observed structures and unobserved processes. We introduce a Bayesian statistical framework that uses a hidden Gaussian random field to capture these latent effects. Applying our method to a simple biophysical model of diffusing particles in an environment with hidden crowders, we show how it detects the crowders’ presence and quantifies the induced spatial heterogeneity. We then demonstrate its utility on biological cell images, revealing how vesicular organelles organize relative to the ER, mitochondria, and the nucleus, while isolating additional spatial variation through the hidden field. This approach enables more comprehensive quantification of emergent spatial phenotypes driven by both known and hidden factors.
Everyone is welcome, and please feel free to invite your colleagues/friends/classmates/students to join us.
If you would like to have the lunch arrangement, please sign up before 15:00 Monday January 27.
- Start date and time
- End date and time
- Location
- Physical Meeting >> CCSS Living Room, Room 4.16, Minnaertgebouw