Frank Miedema studied biochemistry at the University of Groningen, specializing in immunology. As Divisional Manager at the Central Laboratory of the Blood Transfusion Service (CLB) he was responsible for such things as education and research, before going on to become Director of Sanquin Research. Miedema was affiliated with the University of Amsterdam as professor of Immunology of AIDS. In 2004 he became head of the Immunology department at UMC Utrecht. Miedema is a member of various national and international scientific organizations and advisory committees. He has published hundreds of articles in medical journals, including Nature, Science and Lancet, and is one of the initiators of www.scienceintransition.com. The initiators of Science in Transition believe that the scientific system is in need of fundamental reform. Science should be appreciated for the added value it contributes to society and stakeholders in society must participate in decisions regarding the production of knowledge.